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*  The current density of TTX-S and TTX-R Na+ channels fun | Open-i
Persistent tetrodotoxin-resistant (TTX-R) Na(+) (Na(v)1.9/SCN11A) currents are not normally recorded in vagal afferent neurons ... Persistent tetrodotoxin-resistant (TTX-R) Na(+) (Na(v)1.9/SCN11A) currents are not normally recorded in vagal afferent neurons ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2667275_ijbsv05p0293g02&req=4
*  Search of: Tetrodotoxin - List Results - ClinicalTrials.gov
The Purpose of This Study is to Determine if Tetrodotoxin (TTX) is Effective in the Treatment of Pain Resulting From ... Efficacy: long-term efficacy of tetrodotoxin (TTX) in reducing pain and improving quality of life. Safety: long-term safety and ... Safety & Efficacy Study of Subcutaneous Tetrodotoxin for Moderate to Severe Inadequately Controlled Cancer-related Pain. *Pain ... Comparison Study of Liquid and Lyophilized Formulations of Subcutaneous Tetrodotoxin (TTX) in Healthy Volunteers. *Healthy ...
  https://clinicaltrials.gov/ct2/results?term=Tetrodotoxin+&Search=Search
*  Tetrodotoxin | definition of tetrodotoxin by Medical dictionary
... tetrodotoxin explanation free. What is tetrodotoxin? Meaning of tetrodotoxin medical term. What does tetrodotoxin mean? ... Looking for online definition of tetrodotoxin in the Medical Dictionary? ... tetrodotoxin. Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia, Wikipedia. tetrodotoxin. [tet´ro-do-tok″sin] a ... Tetrodotoxin blocks voltage-gated Na+ channels in excitable tissues.. tetrodotoxin. /tet·ro·do·tox·in/ (tet´ro-do-tok″sin) a ...
  https://medical-dictionary.thefreedictionary.com/tetrodotoxin
*  Global Tetrodotoxin Citrate Market Research Report 2017 : ReportsnReports
Notes: Production, means the output of Tetrodotoxin Citrate Revenue, means... ... 112 Pages Report] Check for Discount on Global Tetrodotoxin Citrate Market Research Report 2017 report by QYResearch Group. ... 1 Tetrodotoxin Citrate Market Overview. 1.1 Product Overview and Scope of Tetrodotoxin Citrate. 1.2 Tetrodotoxin Citrate ... Global Tetrodotoxin Citrate Market Research Report 2017 Table of Contents. Global Tetrodotoxin Citrate Market Research Report ...
  http://www.reportsnreports.com/reports/1001470-global-tetrodotoxin-citrate-market-research-report-2017.html
*  Tetrodotoxin Open-label Efficacy and Safety Continuation Study - Full Text View - ClinicalTrials.gov
Experimental: Tetrodotoxin There is only one arm; active treatment with TTX. Biological: Tetrodotoxin 30 µg twice daily for 4 ... Tetrodotoxin Open-label Efficacy and Safety Continuation Study (TEC-006OL). The safety and scientific validity of this study is ... both tetrodotoxin and placebo-treated) to receive or continue to receive tetrodotoxin treatment. ... Tetrodotoxin (TTX) is a selective blocker of Na+ channels and causes analgesia either by decreasing the propagation of action ...
  https://clinicaltrials.gov/ct2/show/study/NCT00726011?show_desc=Y
*  Traumatic Axonal Injury Induces Calcium Influx Modulated by Tetrodotoxin-Sensitive Sodium Channels | Journal of Neuroscience
Injuries with no treatment were performed using CSS with no modifications (n = 9 wells at 25°C; n = 3 at 37°C). Tetrodotoxin ( ... In axons that were pretreated with the Na+channel blocker tetrodotoxin (TTX; 1 μm) and then injured, we found a complete ... Traumatic Axonal Injury Induces Calcium Influx Modulated by Tetrodotoxin-Sensitive Sodium Channels. John A. Wolf, Peter K. Stys ... 1999) Effects of the sodium channel blocker tetrodotoxin on acute white matter pathology after experimental contusive spinal ...
  http://www.jneurosci.org/content/21/6/1923
*  Tetrodotoxin - Wikipedia
Tetrodotoxin has been used clinically to relieve the headache associated with heroin withdrawal. In the U.S., tetrodotoxin ... "Tetrodotoxin". Guide to Pharmacology. IUPHAR/BPS. Kao, C.Y. (1966). "Tetrodotoxin, saxitoxin and their significance in the ... Tetrodotoxin at the US National Library of Medicine Medical Subject Headings (MeSH) Tetrodotoxin: essential data (1999) ... This is the first reported case in which tetrodotoxin has been found to occur in a venom. "Tetrodotoxin". PubChem. National ...
  https://en.wikipedia.org/wiki/Tetrodotoxin
*  Effect of diltiazem and tetrodotoxin on development of anoxic contracture of the guinea pig myocardium | SpringerLink
papillary muscle anoxic contracture diltiazem tetrodotoxin Z. Januškevič Research Institute of Physiology and Pathology of the ... Effect of diltiazem and tetrodotoxin on development of anoxic contracture of the guinea pig myocardium. ...
  https://link.springer.com/article/10.1007/BF00842138
*  Tetrodotoxin-Bupivacaine-Epinephrine Combinations for Prolonged Local Anesthesia - Semantic Scholar
Previous studies showed that in rats, combinations of tetrodotoxin (TTX) with bupivacaine had supra-additive effects on sciatic ... Tetrodotoxin for prolonged local anesthesia with minimal myotoxicity.. *Robert F Padera, Julie Y Tse, Evangelia Bellas, Daniel ... Tetrodotoxin poisoning: a clinical analysis, role of neostigmine and short-term outcome of 53 cases.. *Fazle Rabbi Chowdhury, H ... Tetrodotoxin for moderate to severe cancer pain: a randomized, double blind, parallel design multicenter study.. *Neil A Hagen ...
  https://www.semanticscholar.org/paper/Tetrodotoxin-Bupivacaine-Epinephrine-Combinations-Berde-Athiraman/aa1fd0421fbe3e8180b1683e3befa294a9a79851
*  Binding of tetrodotoxin to squid nerve fibers. Two kinds of receptors? | JGP
The effect of tetrodotoxin on the sodium currents of the squid (Doryteuthis plei and Sepioteuthis sepiodea) giant axons was ... Binding of tetrodotoxin to squid nerve fibers. Two kinds of receptors?. C Sevcik ...
  http://jgp.rupress.org/content/68/1/95
*  Pharmacologic Actions of Tetrodotoxin Studied by Direct Perfusion of the Sinus Node | Circulation Research
The effects of tetrodotoxin on sinus node activity were studied by direct perfusion through its nutrient artery. Tetrodotoxin ... Pharmacologic Actions of Tetrodotoxin Studied by Direct Perfusion of the Sinus Node. JOHN C. TOMLINSON, THOMAS N. JAMES ... Tetrodotoxin also produced complete blockade of sinus node response to vagal stimulation. Blockade of sinus node responses to ... In the open-chest anesthetized dog, direct perfusion of the sinus node artery with tetrodotoxin, 1.0 µg/ml, caused immediate ...
  http://circres.ahajournals.org/content/23/4/501
*  Marine Drugs | Free Full-Text | Tetrodotoxin Blockade on Canine Cardiac L-Type Ca2+ Channels Depends on pH and Redox Potential
Tetrodotoxin (TTX) is believed to be one of the most selective inhibitors of voltage-gated fast Na+ channels in excitable ... Keywords: tetrodotoxin; calcium current; dog heart; pH dependence; redox potential tetrodotoxin; calcium current; dog heart; pH ... Tetrodotoxin Blockade on Canine Cardiac L-Type Ca2+ Channels Depends on pH and Redox Potential. Bence Hegyi 1. ... "Tetrodotoxin Blockade on Canine Cardiac L-Type Ca2+ Channels Depends on pH and Redox Potential." Mar. Drugs 11, no. 6: 2140- ...
  http://www.mdpi.com/1660-3397/11/6/2140/xml
*  Effects of the Sodium Channel Blocker Tetrodotoxin on Acute White Matter Pathology After Experimental Contusive Spinal Cord...
1993) Noninactivating, tetrodotoxin-sensitive Na+ conductance in rat optic nerve axons. Proc Natl Acad Sci USA 90:6976-6980. ... Focal microinjection of tetrodotoxin (TTX), a potent voltage-gated sodium channel blocker, reduces neurological deficits and ... 1997) Local blockade of sodium channels by tetrodotoxin ameliorates tissue loss and long-term functional deficits resulting ... Effects of the Sodium Channel Blocker Tetrodotoxin on Acute White Matter Pathology After Experimental Contusive Spinal Cord ...
  http://www.jneurosci.org/content/19/14/6122
*  Characterization, identification, and screening for tetrodotoxin production by bacteria associated with the ribbon worm ...
... composition of bacteria associated with the proboscis worm Cephalothrix simulawas studied and screening of the tetrodotoxin ( ... Kanoh, S., Distribution of tetrodotoxin in vertebrates, in Recent Advances in Tetrodotoxin Research, Hashimoto, K., Ed., Tokyo ... Yu, V.C-H., Yu, P.H-F., Ho, K-C., and Lee F.W.-F., Isolation and identification of a new tetrodotoxin-producing bacterial ... A Bacillus species was found to be responsible for tetrodotoxin production in proboscis worm C. simula. Vibrio spp. dominated ...
  https://link.springer.com/article/10.1134%2FS0026261714030059
*  An Investigation into Tetrodotoxin (TTX) Levels Associated with the Red Dorsal Spots in Eastern Newt (Notophthalmus viridescens...
An Investigation into Tetrodotoxin (TTX) Levels Associated with the Red Dorsal Spots in Eastern Newt (Notophthalmus viridescens ... C. Y. Kao, "Tetrodotoxin, saxitoxin and their significance in the study of excitation phenomena.," Pharmacological Reviews, vol ... K. Miyazawa and T. Noguchi, "Distribution and origin of tetrodotoxin," Journal of Toxicology - Toxin Reviews, vol. 20, no. 1, ... C. T. Hanifin, E. D. Brodie III, and E. D. Brodie Jr., "A predictive model to estimate total skin tetrodotoxin in the newt ...
  https://www.hindawi.com/journals/jt/2018/9196865/
*  The reaction between tetrodotoxin and membrane sites at the node of Ranvier: its kinetics and dependence on pH | Philosophical...
The reaction between tetrodotoxin and membrane sites at the node of Ranvier: its kinetics and dependence on pH. W. Ulbricht, H ... The reaction between tetrodotoxin and membrane sites at the node of Ranvier: its kinetics and dependence on pH ... The reaction between tetrodotoxin and membrane sites at the node of Ranvier: its kinetics and dependence on pH. ... The reaction between tetrodotoxin and membrane sites at the node of Ranvier: its kinetics and dependence on pH ...
  http://rstb.royalsocietypublishing.org/content/270/908/353
*  EFFECTS OF ATROPINE, TETRODOTOXIN AND LIDOCAINE ON REBOUND EXCITATION OF GUINEA-PIG SMALL INTESTINE | Journal of Pharmacology...
... tetrodotoxin and lidocaine. Procaine, tetrodotoxin and lidocaine increased the latent period of the poststimulus response, ... EFFECTS OF ATROPINE, TETRODOTOXIN AND LIDOCAINE ON REBOUND EXCITATION OF GUINEA-PIG SMALL INTESTINE. J. D. WOOD and D. R. MARSH ... EFFECTS OF ATROPINE, TETRODOTOXIN AND LIDOCAINE ON REBOUND EXCITATION OF GUINEA-PIG SMALL INTESTINE. J. D. WOOD and D. R. MARSH ... EFFECTS OF ATROPINE, TETRODOTOXIN AND LIDOCAINE ON REBOUND EXCITATION OF GUINEA-PIG SMALL INTESTINE. J. D. WOOD and D. R. MARSH ...
  http://jpet.aspetjournals.org/content/184/3/590
*  Tetrodotoxin Promotion | Alomone Labs
Tetrodotoxin (citrate free). A Classic Blocker of a Subset of Nav Channels ... Tetrodotoxin (citrate). A Classic Blocker of a Subset of NaV Channels ...
  https://www.alomone.com/c/tetrodotoxin-promotion-promos-discounts
*  T-Type and Tetrodotoxin-Sensitive Ca2+ Currents Coexist in Guinea Pig Ventricular Myocytes and Are Both Blocked by Mibefradil |...
Well-characterized currents include the T-type Ca2+ current (ICa(T))1 2 and the tetrodotoxin (TTX)-sensitive Na+ current (INa). ... T-Type and Tetrodotoxin-Sensitive Ca2+ Currents Coexist in Guinea Pig Ventricular Myocytes and Are Both Blocked by Mibefradil. ... T-Type and Tetrodotoxin-Sensitive Ca2+ Currents Coexist in Guinea Pig Ventricular Myocytes and Are Both Blocked by Mibefradil ... T-Type and Tetrodotoxin-Sensitive Ca2+ Currents Coexist in Guinea Pig Ventricular Myocytes and Are Both Blocked by Mibefradil ...
  http://circres.ahajournals.org/content/86/6/628
*  Separation of the action potential into a Na-channel spike and a K-channel spike by tetrodotoxin and by tetraethylammonium ion...
The effects of tetrodotoxin (TTX) and of tetraethylammonium ion (TEA+) on such action potentials were studied. The results are ... Separation of the action potential into a Na-channel spike and a K-channel spike by tetrodotoxin and by tetraethylammonium ion ... Separation of the action potential into a Na-channel spike and a K-channel spike by tetrodotoxin and by tetraethylammonium ion ...
  http://jgp.rupress.org/content/76/3/337
*  Tetrodotoxin-sensitive and -resistant Na+ channel currents in subsets of small sensory neurons of rats. - Semantic Scholar
In this study, we determined the possible difference in tetrodotoxin-sensitive (TTX-S) and -resistant (TTX-R) Na+ channel ... Tetrodotoxin-sensitive and -resistant Na+ channel currents in subsets of small sensory neurons of rats.. @article{ ... In this study, we determined the possible difference in tetrodotoxin-sensitive (TTX-S) and -resistant (TTX-R) Na+ channel ... Wu2004TetrodotoxinsensitiveA, title={Tetrodotoxin-sensitive and -resistant Na+ channel currents in subsets of small sensory ...
  https://www.semanticscholar.org/paper/Tetrodotoxin-sensitive-and-resistant-Na%2B-channel-in-Wu-Pan/57fe5911c79e4fb72d1e1c166b74dd0403cf31e2
*  Binding of monoclonal antibodies to cytoplasmic tetrodotoxin-sensitive brain protein with human lymphocytes - Semantic Scholar
... can form tetrodotoxin-sensitive sodium channels, were first described in 1979 [5]. It is claimed that these proteins are ... Recently a cytoplasmic tetrodotoxin-sensitive protein (CTSP), possessing these properties, has been isolated from bovine brain ... Binding of monoclonal antibodies to cytoplasmic tetrodotoxin-sensitive brain protein with human lymphocytes. @article{ ... can form tetrodotoxin-sensitive sodium channels, were first described in 1979 [5]. It is claimed that these proteins are ...
  https://www.semanticscholar.org/paper/Binding-of-monoclonal-antibodies-to-cytoplasmic-Pinchuk-Pinchuk/f65ab307337ba92b2d29974da2b933baad8ca896
*  Short Hairpin RNA-mediated Selective Knockdown of NaV1.8 Tetrodotoxin-resistant Voltage-gated Sodium Channel in Dorsal Root...
Pharmacologically, VGSCs can be broadly classified into those that are blocked by tetrodotoxin (tetrodotoxin sensitive) and ... In the presence of tetrodotoxin, the resulting family of currents represents tetrodotoxin-resistant current flowing mostly ... lentivirus only expressing the EGFP reporter or the pan-tetrodotoxin-sensitive shRNA designed to knock down the tetrodotoxin- ... Pan-TTXs = pan-tetrodotoxin sensitive. ( C ) HEK293-NaV1.8 cell line infected with lentivirus expressing NaV1.8 (6033)-short ...
  http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1923738
*  Kinetic basis for insensitivity to tetrodotoxin and saxitoxin in sodium channels of canine heart and denervated rat skeletal...
The single-channel blocking kinetics of tetrodotoxin (TTX), saxitoxin (STX), and several STX derivatives were measured for ... Concentration-Dependent Effects of Tetrodotoxin in Function of Adult Rat and Rabbit Heart. *Yusheng Qu, BaoXi Gao, Mei Fang, ... The Tetrodotoxin Binding Site Is within the Outer Vestibule of the Sodium Channel. *Harry A. Fozzard, Gregory M. Lipkind ... Use-dependent block of the voltage-gated Na+ channel by tetrodotoxin and saxitoxin: Effect of pore mutations that change ionic ...
  https://www.semanticscholar.org/paper/Kinetic-basis-for-insensitivity-to-tetrodotoxin-and-Guo-Uehara/f9fdbd043f0ebd0e756fa229611cd7f6134fc9fe
*  "Biosynthetic studies of tetrodotoxin and its anticancer activities ass" by Zhe Xiao
Xiao, Zhe, "Biosynthetic studies of tetrodotoxin and its anticancer activities assessment in vitro" (2014). Open Access Theses ... Keywords: Tetrodotoxin (TTX), Bacterial synthesis, Anticancer, VGSCs ...
  https://repository.hkbu.edu.hk/etd_oa/56/