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*  Disopyramide - Wikipedia
Another concern about disopyramide has been the hypothetical potential for inducing sudden death from its type 1 anti- ... This effect is particularly well suited in the treatment of ventricular tachycardia as it slows the action potential ... When used in patients resistant to beta-blockade, disopyramide is effective in 60% of cases, reducing symptoms and gradient to ... Disopyramide (INN, trade names Norpace and Rythmodan) is an antiarrhythmic medication used in the treatment of ventricular ...
  https://en.wikipedia.org/wiki/Disopyramide
*  Torsades de pointes: Treatment, symptoms, and causes
Torsades de pointes is an uncommon type of ventricular tachycardia that can be potentially life-threatening. Learn more about ... People without syncope, ventricular tachycardia, or a family history of the condition may only be monitored by a doctor rather ... Torsades de pointes is a serious arrhythmia that can lead to sudden cardiac death in some cases. However, the outlook for ... antiarrhythmic drugs, including quinidine, procainamide, and disopyramide. *antipsychotics or tricyclic antidepressants * ...
  https://www.medicalnewstoday.com/articles/320619.php?sr
*  Quinidine Gluconate Extended-Release Tablets (quinidine gluconate) dose, indications, adverse effects, interactions... from PDR...
Cases of QT prolongation, TdP, ventricular tachycardia, and sudden death have been reported during postmarketing use of ... Edrophonium may not terminate paroxysmal supraventricular tachycardias in patients receiving quinidine, disopyramide or ... Bleeding risk may be increased; monitor patients closely for signs and symptoms of bleeding. Betrixaban is a substrate of P-gp ... Ventricular tachycardia, including torsade de pointes and monomorphic ventricular tachycardia can occur with excessive ...
  http://www.pdr.net/drug-summary/Quinidine-Gluconate-Extended-Release-Tablets-quinidine-gluconate-789
*  Hypertrophic Cardiomyopathy: Management and Genetic Counseling - The Clinical Advisor
... assessment of risk of sudden cardiac death, and treatment of symptoms. ... Nonsustained ventricular tachycardia in the presence of other risk modifiers. Abnormal blood pressure in the presence of other ... "Multicenter study of the efficacy and safety of disopyramide in obstructive hypertrophic cardiomyopathy". J Am Coll Cardiol. ... Sudden cardiac death risk assessment. The overall incidence of sudden cardiac death among HCM patients is approximately 1% per ...
  https://www.clinicaladvisor.com/cardiology/hypertrophic-cardiomyopathy-management-and-genetic-counseling/article/583777/
*  Ventricular tachycardia - ONA
The goal of long-term therapy is to prevent sudden cardiac death and recurrence of ventricular arrhythmia. Multiple ICD trials ... therefore the presence of specific symptoms is not helpful in determining the tachycardia mechanism in a patient with a WCT of ... Antiarrhythmic drugs implicated include class IA agents (e.g., quinidine, procainamide, disopyramide), class IC agents (e.g., ... Ventricular tachycardia/Fibrillation, Wide complex tachycardias. *Ventricular Tachycardia with No Structural Heart Disease: ...
  http://www.oncologynurseadvisor.com/hospital-medicine/ventricular-tachycardia/article/599663/
*  Quinidine sulfate | definition of quinidine sulfate by Medical dictionary
... paradoxical tachycardia, ventricular tachycardia, ventricular fibrillation, ventricular flutter, ventricular ectopy, torsades ... Its use is associated with an increased risk, in some patients, of sudden death. ... Disopyramide: increased disopyramide or decreased quinidine blood level. Potassium, urinary alkalizers: increased blood level ... Watch for signs and symptoms of blood dyscrasias.. Closely monitor respiratory status. Stay alert for asthma attacks and ...
  https://medical-dictionary.thefreedictionary.com/quinidine+sulfate
*  Prognostic Value of Quantitative Contrast-Enhanced Cardiovascular Magnetic Resonance for the Evaluation of Sudden Death Risk in...
Non-sustained ventricular tachycardia in hypertrophic cardiomyopathy: an independent marker of sudden death risk in young ... Sudden death was defined as unexpected sudden collapse occurring within 1 hour from the onset of symptoms in patients with a ... disopyramide, or amiodarone) and those not taking these medications (P=0.37). In addition, 118 patients experienced adverse HCM ... is the most common cause of sudden death in the young, although not all patients eligible for sudden death prevention with an ...
  http://circ.ahajournals.org/content/130/6/484
*  Hypertrophic cardiomyopathy - Wikipedia
... spontaneous sustained ventricular tachycardia, family history of premature sudden death, unexplained syncope, LV thickness ... For people whose symptoms are not relieved by the above treatments, disopyramide can be considered for further symptom relief. ... For children with HCM, treatment strategies aim to reduce disease symptoms and lower the risk of sudden death. Due to the ... Mar 2009). "Sudden deaths in young competitive athletes: analysis of 1866 deaths in the United States, 1980-2006". Circulation ...
  https://en.wikipedia.org/wiki/Hypertrophic_cardiomyopathy
*  Outpatient Approach to Palpitations - - American Family Physician
Patients with supraventricular tachycardia, long QT syndrome, ventricular tachycardia, or palpitations associated with syncope ... Ventricular and atrial premature contractions are common cardiac causes of palpitations; prognostic significance is dictated by ... Discerning cardiac from noncardiac causes is important given the potential risk of sudden death in those with an underlying ... ESC 2006 guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. J ...
  https://www.aafp.org/afp/2011/0701/p63.html
*  Sodium Channel Blockers - The Group 1 of Antiarrhythmic Drugs | Lecturio
Antiarrhythmic drugs ✓, mechanism of action of sodium channel blockers ✓, disopyramide ✓, quinidine ✓. Read more now! ... Like disopyramide, it can also precipitate heart failure.. Bigeminy and premature ventricular tachycardia are characteristic ... As with other drugs in the class A group, quinidine is also proarrhythmogenic and has the potential to cause sudden death, thus ... The symptoms of a lupus-like syndrome occur in very few patients and, even in those patients, it is self-limiting after the ...
  https://www.lecturio.com/magazine/sodium-channel-blockers/
*  Increased GGT and Level of consciousness symptoms - Symptom Checker - check medical symptoms at RightDiagnosis
List of causes of Increased GGT and Level of consciousness symptoms, alternative diagnoses, rare causes, misdiagnoses, patient ... Ventricular tachycardia. 1432. Ventricular tachycardia, catecholaminergic polymorphic, 1. 1433. Ventricular tachycardia, ... Death Angel poisoning. 643. Death Camas poisoning. 644. Death, Sudden, Cardiac. 645. Decompression sickness. 646. Decreased ... Disopyramide toxicity. 669. Disulfiram toxicity. 670. Double outlet -- right ventricle II. 671. Double tachycardia induced by ...
  http://symptoms.rightdiagnosis.com/cosymptoms/increased-ggt/level-of-consciousness-symptoms-sall.htm
*  Safety of Outpatient Initiation of Disopyramide for Obstructive Hypertrophic Cardiomyopathy Patients | Journal of the American...
Conclusions Initiation of disopyramide in the outpatient setting is safe and the risk of subsequent sudden cardiac death is low ... After initiation of disopyramide and increase in dose to 600 mg daily, his symptoms resolved and gradients diminished to 15 mm ... Absolute contraindications for disopyramide include reduced left ventricular (LV) systolic function, congenital long QT ... Although Bazett's formula is the most commonly used, it is less accurate in relative tachycardia or bradycardia and therefore ...
  http://jaha.ahajournals.org/content/6/6/e005152
*  Basic Concepts
Sudden Death in athletes Treatment • β- blockers • Ca+ 2 channel blockers • Disopyramide • Echocardiography • Catheterization: ... Ventricular Arrhythmias Ventricular Tachycardia • Rate , 120 beats / min Ventricular Fibrillation • Significant electrical ... Residual - Previous episode but no prominent psychotic symptoms at evaluation, some negative symptoms. • Positive Symptoms: ... Pulmonary Thromboembolism: Sudden onset of dyspnea along with tachycardia ECG Right Axis Deviation h/o long term immobility ...
  http://spotidoc.com/doc/22634/basic-concepts
*  Caprelsa (Vandetanib): Side Effects, Interactions, Warning, Dosage & Uses
... ventricular tachycardia and sudden deaths have occurred in patients treated with CAPRELSA. ... Call your healthcare provider right away if you experience any of these symptoms. *Skin rash or acne ... Avoid administration of CAPRELSA with anti-arrhythmic drugs (including but not limited to amiodarone, disopyramide, ... AND SUDDEN DEATH. CAPRELSA can prolong the QT interval. Tors ades de pointes and s udden death have occurred in patients ...
  https://www.rxlist.com/caprelsa-drug.htm
*  Antiarrhythmic effects of azimilide in atrial fibrillation: efficacy and dose-response | JACC: Journal of the American College...
The other death in a patient receiving azimilide 50 mg QD was unobserved, presumed sudden death 35 days after randomization. ... 1988) Supraventricular tachycardia mimicking ventricular tachycardia during flecainide treatment. Am J Cardiol 62:1303-1306. ... normal sinus rhythm is punctuated by periods of abnormal rhythm that is recognized by patients as the sudden onset of symptoms ... The latter patient was also taking the antiarrhythmic drug disopyramide, a protocol violation; an explanation for the syncope ...
  http://www.onlinejacc.org/content/36/3/794
*  Clinical Phenotype and Outcome of Hypertrophic Cardiomyopathy Associated With Thin-Filament Gene Mutations | JACC: Journal of...
nonsustained ventricular tachycardia. NYHA. New York Heart Association. SCD. sudden cardiac death. TNNT2. cardiac troponin T ... leading to congestive symptoms, triphasic left ventricular filling, and more severe diastolic dysfunction, compared with thick- ... and disopyramide (Table 2). Predictably, they were more frequently treated with diuretics and angiotensin-converting enzyme ... 11%; p = 0.002); and 5) similar rates of malignant ventricular arrhythmias and sudden cardiac death (p = 0.593). ...
  http://www.onlinejacc.org/content/64/24/2589
*  Distribution and Prognostic Significance of Fragmented QRS in Patients With Brugada Syndrome | Circulation: Arrhythmia and...
sudden cardiac death. *ventricular fibrillation. Introduction. WHAT IS KNOWN. *. Fragmented QRS (fQRS) is known to be a marker ... Univariable and multivariable analyses of fragmented QRS (fQRS) for predicting ventricular tachycardia (VT)/ventricular ... or no symptoms (n=277). These mild symptoms were not associated with ventricular tachyarrhythmias, and we consider these 316 ... disopyramide, 6 patients; quinidine, 7 patients; cilostazol, 1 patient). ...
  http://circep.ahajournals.org/content/10/3/e004765
*  Hypertrophic cardiomyopathy - WikEM
Symptoms: Syncope or sudden death most common *Also exertional dyspnea, chest pain, syncope, dizziness, palpitations, or CHF ... Symptoms made worse by exertion *Increasing ventricular contractility further narrows outflow as volume is lost ... Avoid disopyramide alone with out BB or CCB. *Avoid positive inotropic vasopressors (dopamine, dobutamine, norepinephrine, epi) ... Limit tachycardia *Beta blockers. *Avoid vasodilators (no nitrates). *Maintain sinus rythm (i.e. cardiovert A. fib) ...
  https://www.wikem.org/wiki/Hypertrophic_cardiomyopathy
*  Pre-excitation syndrome (WPW) - Cancer Therapy Advisor
Dreifus, LS, Haiat, R, Watanabe, Y. "Ventricular fibrillation". A possible mechanism of sudden death in patients and Wolff- ... nodofascicular tachycardia, supraventricular tachycardia with aberrancy, and ventricular tachycardia.. D. Physical Examination ... Male gender or young age may predispose to the development of symptoms or sudden cardiac death (SCD). In patients with an ... Disopyramide should not be used in patients with asymptomatic, non-life-threatening ventricular arrhythmias and recent (,2 ...
  http://www.cancertherapyadvisor.com/hospital-medicine/pre-excitation-syndrome-wpw/article/599540/
*  Tambocor - FDA prescribing information, side effects and uses
documented ventricular arrhythmias, such as sustained ventricular tachycardia (sustained VT), that in the judgment of the ... In pediatric patients with structural heart disease, Tambocor has been associated with cardiac arrest and sudden death. ... reentrant tachycardia and other supraventricular tachycardias of unspecified mechanism associated with disabling symptoms. -. ... There has been little experience with the coadministration of Tambocor and either disopyramide or verapamil. Because both of ...
  https://www.drugs.com/pro/tambocor.html
*  Metoprolol (Professional Patient Advice) - Drugs.com
Prevention of reinfarction and sudden death after myocardial infarction; Ventricular arrhythmias; Thyrotoxicosis ... Supraventricular tachycardia (atrioventricular nodal reentrant tachycardia, atrioventricular reentrant tachycardia, atrial ... Disopyramide: May enhance the bradycardic effect of Beta-Blockers. Beta-Blockers may enhance the negative inotropic effect of ... When concurrent use is not avoidable, monitor patients closely for signs/symptoms of toxicity. Consider therapy modification ...
  https://www.drugs.com/ppa/metoprolol.html
*  Ventricular Tachycardia (VT) - AHealthyMe - Blue Cross Blue Shield of Massachusetts
Ventricular tachycardia is a fast, abnormal heart rate that begins in the lower chambers of the heart. It can become life- ... or no symptoms at all. But for others, VT can be very dangerous. It can lead to sudden cardiac arrest and death. ... Ventricular Tachycardia (VT). What is ventricular tachycardia (VT)?. Ventricular tachycardia (VT) is a fast, abnormal heart ... Disopyramide capsules * Disopyramide extended-release capsules * Mexiletine capsules * Moricizine tablets * Procainamide ...
  http://www.ahealthyme.com/Library/DiseasesConditions/Adult/Cardiovascular/134,231
*  Learn: Pharmacology - Block 2 - Part 1 (by davidwurbel7) - Memorize.com - Remember and Understand
Toxicity symptoms include anticholinergic effects (anti-DUMBELLS). Disopyramide. Class IB drug. Particularly useful in the Rx ... Used for long term therapy to decrease the rate of sudden death following MI. Have strong antifibrillary effects in ischemic ... Uses: ventricular arrhythmia following MI. Lidocaine. Toxicity symptoms include CNS effects: circum-oral numbness, drowsiness, ... Used to treat stable, narrow complex SVT and regular monomorphic wide-complex tachycardia. Adenosine. ...
  http://memorize.com/pharmacology-block-2-part-1/davidwurbel7
*  Augmented ST-Segment Elevation During Recovery From Exercise Predicts Cardiac Events in Patients With Brugada Syndrome | JACC:...
The clinical end point was defined as the occurrence of sudden cardiac death, ventricular fibrillation, or sustained ... polymorphic ventricular tachycardia, family history of SCD ,45 years of age, family history of BrS, inducibility of VF with ... The incidence of cardiac events during follow-up in the subgroups according to symptoms before exercise testing is shown in ... disopyramide 300 mg daily for 1 patient, and amiodarone 200 mg daily for another patient), 2 patients who had AF (quinidine 300 ...
  http://www.onlinejacc.org/content/56/19/1576