*  KEGG PATHWAY: Synaptic vesicle cycle - Homo sapiens (human)
Synaptic vesicle cycle - Homo sapiens (human) [ Pathway menu , Organism menu , Pathway entry , Download KGML , Show description ... Communication between neurons is mediated by the release of neurotransmitter from synaptic vesicles (SVs). At the nerve ... After fusion, the vesicle is retrieved by endocytosis and reloaded for another round of exocytosis. ...
  http://www.genome.jp/kegg-bin/show_pathway?131081650219559/hsa04721.args
*  Involvement of Ca2+ Channel Synprint Site in Synaptic Vesicle Endocytosis | Journal of Neuroscience
Involvement of Ca2+ Channel Synprint Site in Synaptic Vesicle Endocytosis. Hiroyasu Watanabe, Takayuki Yamashita, Naoto Saitoh ... Involvement of Ca2+ Channel Synprint Site in Synaptic Vesicle Endocytosis. Hiroyasu Watanabe, Takayuki Yamashita, Naoto Saitoh ... In the nerve terminal, synaptic vesicles are docked on an active zone of 200-300 nm in diameter, in which VGCCs are thought to ... Involvement of Ca2+ Channel Synprint Site in Synaptic Vesicle Endocytosis Message Subject (Your Name) has forwarded a page to ...
  http://www.jneurosci.org/content/30/2/655
*  LIN7C - Protein lin-7 homolog C - Homo sapiens (Human) - LIN7C gene & protein
... to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta- ... The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic ... vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) ... CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper ...
  http://www.uniprot.org/uniprot/Q9NUP9
*  Frontiers | Live imaging of synaptic vesicle release and retrieval in dopaminergic neurons | Frontiers in Neural Circuits
Finally, our assay can also be used to investigate the effects of genetic and chemical modulation of the synaptic vesicle cycle ... These projections secrete dopamine from small clear synaptic vesicles (SVs) in axonal varicosities. DA signaling has unique ... Thus, limited vesicle depletion likely arises from a stimulus frequency-dependent acceleration of DA SV endocytosis or re- ... Thus, limited vesicle depletion likely arises from a stimulus frequency-dependent acceleration of DA SV... ...
  https://www.frontiersin.org/articles/10.3389/neuro.04.003.2009/full
*  The organization of synaptic vesicles at tonically transmitting connections of locust visual interneurons - ePrints - Newcastle...
The organization of synaptic vesicles at tonically transmitting connections of locust visual interneurons. *Lookup NU author(s) ...
  http://eprint.ncl.ac.uk/pub_details2.aspx?pub_id=82165
*  Properties of fast endocytosis at hippocampal synapses | Philosophical Transactions of the Royal Society B: Biological Sciences
Traditionally, experimental accessibility of the synaptic vesicle cycle in central neuronal synapses has been largely limited ... Regulation of synaptic transmission is a widespread means for dynamic alterations in nervous system function. In several cases ... been made possible by the introduction of styryl dyes such as FM1-43 as fluorescent markers for recycling synaptic vesicles. ... regulation targets vesicular recycling in presynaptic terminals and may result in substantial changes in efficiency of synaptic ...
  http://rstb.royalsocietypublishing.org/content/354/1381/337
*  Synaptic Vesicle Fusion Followed by Clathrin-Mediated Endocytosis - Docs.com
Many of the molecular components that are involved in synaptic vesicle priming, docking, fusion, and endocytosis are shown. ... Although the process in the animation describes synaptic vesicle cycling, similar cellular processes occur for most calcium- ... The animation shows calcium-stimulated exocytosis of synaptic vesicles followed by clathrin-mediated vesicle recycling. ... The animation shows calcium-stimulated exocytosis of synaptic vesicles followed by clathrin-mediated vesicle recycling. Many of ...
  https://docs.com/learning-registry/58215/synaptic-vesicle-fusion-followed-by
*  Glen Ernstrom | Middlebury
How neurons control the appropriate quantity of neurotransmitters loaded into synaptic vesicles is not known. Our lab uses a ... A range of neural disorders can result if synaptic vesicles are not adequately loaded with neurotransmitter. ... genetic approach to identify which genes control neurotransmitter loading into synaptic vesicles in the model organism, the ... Reliable nerve signaling requires the uniform, quantal release of neurotransmitters from synaptic vesicles. ...
  http://www.middlebury.edu/academics/bio/faculty/node/454427
*  Neurotransmitter Secretion along Growing Nerve Processes: Comparison with Synaptic Vesicle Exocytosis | JCB
... synaptic vesicles are likely to contain the basic complement of proteins required for synaptic vesicle docking, fusion, and ... 1996) The synaptic vesicle cycle: a single vesicle budding step involving clathrin and dynamin. J Cell Biol 133:1237-1250, pmid ... Synaptic Vesicle Recycling and Short-term Plasticity at the Nerve Terminal and along the Axon. Generation of carrier vesicles ... The vesicles associated with constitutive membrane recycling along the axon contain some of synaptic vesicle markers (Matteoli ...
  http://jcb.rupress.org/content/144/3/507
*  VAT1 - Wikipedia
Synaptic vesicle membrane protein VAT-1 homolog is a protein that in humans is encoded by the VAT1 gene. Synaptic vesicles are ... The protein encoded by this gene is an abundant integral membrane protein of cholinergic synaptic vesicles and is thought to be ... "Entrez Gene: VAT1 vesicle amine transport protein 1 homolog (T. californica)". Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008 ...
  https://en.wikipedia.org/wiki/VAT1
*  'synaptic vesicles' Protocols and Video...
... synaptic vesicles' include 'In vivo Visualization of Synaptic Vesicles Within Drosophila Larval Segmental Axons', 'Examination ... An Optical Assay for Synaptic Vesicle Recycling in Cultured Neurons Overexpressing Presynaptic Proteins', 'Use of Synaptic Zinc ... Fragmentation and Changes in Synaptic Protein Density Using Confocal Fluorescence Microscopy', 'Studying Synaptic Vesicle Pools ... of Synaptic Vesicle Recycling Using FM Dyes During Evoked, Spontaneous, and Miniature Synaptic Activities', 'FM Dye Cycling at ...
  https://www.jove.com/keyword/synaptic+vesicles
*  KEGG PATHWAY: Synaptic vesicle cycle
Synaptic vesicle cycle [ Pathway menu , Organism menu , Pathway entry , Download KGML , Show description , User data mapping ] ... Communication between neurons is mediated by the release of neurotransmitter from synaptic vesicles (SVs). At the nerve ... After fusion, the vesicle is retrieved by endocytosis and reloaded for another round of exocytosis. ...
  http://www.genome.jp/kegg-bin/show_pathway?ko04721+K15293
*  The Kinetics of Synaptic Vesicle Reacidification at Hippocampal Nerve Terminals | Journal of Neuroscience
... located in synaptic vesicle membranes (Miesenbock et al., 1998). In fully acidified (pH ∼ 5.5) synaptic vesicles of a resting ... allowing SpH to rapidly signal synaptic vesicle fusion with the plasma membrane or changes in synaptic vesicle pH. Gandhi and ... synaptic. Introduction. In newly endocytosed synaptic vesicles, a proton electrochemical gradient (Grabe and Oster, 2001) ... Fernandez-Alfonso T, Ryan TA (2004) The kinetics of synaptic vesicle pool depletion at CNS synaptic terminals. Neuron 41:943- ...
  http://www.jneurosci.org/content/26/8/2313
*  Colocalization of synapsin and actin during synaptic vesicle recycling | JCB
Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation. J. Cell Biol. 96:1374-1388. ... but synaptic vesicle clustering is almost completely abolished and the number of synaptic vesicles is drastically reduced (Li ... The majority of synaptic vesicles enmeshed in the cytomatrix were labeled for synapsin, as were the clustered synaptic vesicles ... 900 clustered synaptic vesicles, roughly equivalent to one half of an average reticulospinal synaptic vesicle cluster, and 40 ...
  http://jcb.rupress.org/content/161/4/737
*  LRRK2 Controls Synaptic Vesicle Storage and Mobilization within the Recycling Pool | Journal of Neuroscience
LRRK2 silencing alters synaptic vesicle distribution. Synaptic vesicles within the presynaptic compartment are distributed in ... 1999) Tetanus toxin blocks the exocytosis of synaptic vesicles clustered at synapses but not of synaptic vesicles in isolated ... 1993) Synaptic vesicle phosphoproteins and regulation of synaptic function. Science 259:780-785. ... LRRK2 Controls Synaptic Vesicle Storage and Mobilization within the Recycling Pool. Giovanni Piccoli, Steven B. Condliffe, ...
  http://www.jneurosci.org/content/31/6/2225
*  Vesicular Monoamine and Glutamate Transporters Select Distinct Synaptic Vesicle Recycling Pathways | Journal of Neuroscience
... of synaptic vesicles.. Reporters based on GFP can directly interrogate multiple aspects of the synaptic vesicle cycle. Fused to ... 2007) Synaptic vesicles recycling spontaneously and during activity belong to the same vesicle pool. Nat Neurosci 10:145-147. ... 2007) Single-vesicle imaging reveals that synaptic vesicle exocytosis and endocytosis are coupled by a single stochastic mode. ... short-term synaptic depression due to synaptic vesicle depletion (Dittman et al., 2000) would reduce the amount of dopamine ...
  http://www.jneurosci.org/content/30/23/7917
*  Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease | PNAS
1999) SV2C is a synaptic vesicle protein with an unusually restricted localization: Anatomy of a synaptic vesicle protein ... Members of the synaptic vesicle glycoprotein 2 (SV2) family of proteins are involved in synaptic function throughout the brain ... 2013) Alignment of synaptic vesicle macromolecules with the macromolecules in active zone material that direct vesicle docking ... 2006) The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves. FEBS Lett 580(8):2011- ...
  http://www.pnas.org/content/114/11/E2253
*  TURNOVER OF TRANSMITTER AND SYNAPTIC VESICLES AT THE FROG NEUROMUSCULAR JUNCTION | JCB
TURNOVER OF TRANSMITTER AND SYNAPTIC VESICLES AT THE FROG NEUROMUSCULAR JUNCTION. B. Ceccarelli, W. P. Hurlbut, A. Mauro ... These results suggest (a) that synaptic vesicles fuse with, and re-form from, the membrane of the nerve terminal during and ... During 4 h of stimulation at 2/s many new vesicles were formed from the axolemma and the quantity of transmitter secreted was ... Horseradish peroxidase or dextran was added to the bathing solution and used as a tracer to detect the formation of vesicles ...
  http://jcb.rupress.org/content/57/2/499
*  The Molecular Machinery for Synaptic Vesicle Endocytosis | Springer for Research & Development
Synaptic Vesicle Eps15 Homology Synaptic Vesicle Recycling Clathrin Coat Endocytic Machinery These keywords were added by ... Tandem MS analysis of brain clathrin-coated vesicles reveals their critical involvement in synaptic vesicle recycling. Proc. ... Delayed reentry of recycling vesicles into the fusion-competent synaptic vesicle pool in synaptojanin 1 knockout mice. Proc. ... a novel DENN domain-containing protein of neuronal clathrin-coated vesicles functioning in synaptic vesicle endocytosis. J. ...
  https://rd.springer.com/chapter/10.1007/978-0-387-77232-5_5
*  Synaptic Vesicle-Recycling Machinery Components as Potential Therapeutic Targets | Pharmacological Reviews
Synaptic Vesicle-Recycling Machinery Components as Potential Therapeutic Targets. Ying C. Li and Ege T. Kavalali ... Synaptic Vesicle-Recycling Machinery Components as Potential Therapeutic Targets Message Subject (Your Name) has forwarded a ... Key events during the synaptic vesicle cycle-such as exocytosis and endocytosis-require formation and disassembly of protein ... Therefore, it is not surprising that subtle alterations in synaptic vesicle cycle-associated proteins directly or indirectly ...
  http://pharmrev.aspetjournals.org/content/69/2/141
*  Product - Page 2 of 13, Research 'Synaptic vesicles' | Genetex Inc.
Browse over 121 Product, covering popular research areas including cancer, neuroscience, epigenetics, cell biology, apoptosis, autophagy, hypoxia, immunology and tested in human, mouse, rat, zebrafish et., al. by WB, ICC/IF, IHC, ChIP et., al.
  http://www.genetex.com/Web/search/Catalog/2?Research=0910
*  Dithiocarbamate Pesticides Affect Glutamate Transport in Brain Synaptic Vesicles | Journal of Pharmacology and Experimental...
Dithiocarbamate Pesticides Affect Glutamate Transport in Brain Synaptic Vesicles. Andrea Vaccari, Pierluigi Saba, Ignazia Mocci ... Dithiocarbamate Pesticides Affect Glutamate Transport in Brain Synaptic Vesicles. Andrea Vaccari, Pierluigi Saba, Ignazia Mocci ... Dithiocarbamate Pesticides Affect Glutamate Transport in Brain Synaptic Vesicles. Andrea Vaccari, Pierluigi Saba, Ignazia Mocci ... Dithiocarbamate Pesticides Affect Glutamate Transport in Brain Synaptic Vesicles Message Subject (Your Name) has forwarded a ...
  http://jpet.aspetjournals.org/content/288/1/1/tab-e-letters
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Coated Vesicles, Receptor, Epidermal Growth Factor, Actins, Fluorescence, Endocytosis, Microscopy, STORM, super-resolution ... astrocytic receptor signaling is affected by changes in neuronal activity has important implications for both normal synaptic ...
  https://www.jove.com/visualize/abstract/23300962/long-term-in-vivo-imaging-of-multiple-organs-at-the-single-cell-level
*  Apical targeting of syntaxin 3 is essential for epithelial cell polarity | JCB
The interaction of synaptic vesicle-associated membrane protein/synaptobrevin with botulinum neurotoxins D and F. FEBS Lett. ... In neurons, syntaxin 1 binds to SNAP-25 to form a functional t-SNARE that can interact with the v-SNARE on synaptic vesicles. ... A targeting signal in VAMP regulating transport to synaptic vesicles. Cell. 81:581-589. ... it was shown to be required for targeting to synaptic vesicles and endocytosis (Grote et al., 1995), although this coincidence ...
  http://jcb.rupress.org/content/173/6/937