*  Myocardial infarction - Factbites
Myocardial bridging usually has a benign prognosis, but some cases associated with myocardial ischemia, infarction, and sudden ... tissue death due to oxygen starvation or ischemia). Acute myocardial infarction is usually characterized by varying degrees of ... Acute Myocardial Infarction. Myocardial infarction occurs when myocardial ischemia exceeds a critical threshold and overwhelms ... This is a case of acute myocardial infarction caused by coronary thrombosis in the setting of myocardial bridging. ...
  http://www.factbites.com/topics/Myocardial-infarction
*  Abstract 1712: Deep Myocardial Bridging is a Risk Factor for Sudden Death in Hypertrophic Cardiomyopathy | Circulation
Myocardial bridging (MB) of the left anterior descending (LAD) coronary artery segment has been linked with myocardial ischemia ... Abstract 1712: Deep Myocardial Bridging is a Risk Factor for Sudden Death in Hypertrophic Cardiomyopathy. Cristina Basso, Barry ... Abstract 1712: Deep Myocardial Bridging is a Risk Factor for Sudden Death in Hypertrophic Cardiomyopathy ... Abstract 1712: Deep Myocardial Bridging is a Risk Factor for Sudden Death in Hypertrophic Cardiomyopathy ...
  http://circ.ahajournals.org/content/114/Suppl_18/II_334.3
*  Epicardial Coronary Artery Compression Secondary to Pericardial Adhesions Demonstrated by Multi-Modality Imaging, and Treated...
Clinical relevance of myocardial bridging severity: single center experience. Eur J Clin Invest. 2009;39:110-115. ... A single chamber cardiac defibrillator was implanted for secondary prevention of sudden cardiac death before discharge. Our ... predominantly felt that she likely had a horizontal fibrous band compressing the coronary segments and causing acute ischemia, ... This presentation is not consistent with primary myocardial bridging, which involves left anterior descending artery in 93% of ...
  http://circ.ahajournals.org/content/130/15/e129
*  Exercise sub-cluster 88
Several previous studies suggest that myocardial bridging (MB) is associated with ischemia and rhythm disturbances. We sought ... There has been scrutiny of CEWs and their potential role in the occasional sudden death of subjects in custody. There is a ... The Brugada syndrome has been described as a genetic disorder involving aborted sudden cardiac death in patients with ... remains a serious problem and an important cause of death. Standard pulse oximetrie in low acuity settings is nowadays ...
  http://www.biomedsearch.com/cluster/75/Exercise/sub-88-p7.html
*  The pathophysiology of acute coronary syndromes | Heart
Mechanisms of myocardial ischaemia in non-occluding coronary thrombosis. * Distal embolisation of aggregates of platelets ... 1985) Unstable angina with fatal outcome: dynamic coronary thrombosis leading to infarction and/or sudden death. Circulation 71 ... and compression by myocardial bridges. Thrombosis is also the major initiating factor in unstable angina, particularly when ... Given the importance of thrombosis as the trigger for acute myocardial ischaemia, it is necessary to know something about the ...
  http://heart.bmj.com/content/83/3/361
*  Cardiovascular Journal of Africa: Vol 27, Issue 4, July/August 2016
Introduction: Myocardial bridging (MB) is a congenital variant of the coronary artery in which a portion of the epicardial ... exercise-induced dysrhythmias or even sudden death. MB may be related to increased inflammatory and atherosclerotic processes. ... Although it is considered a benign anomaly, it may lead to such complications as myocardial ischaemia, acute coronary syndrome ... Title: A rare cause of early repolarisation in an adolescent boy with chest pain: myocardial bridging. Authors: M Deveci, K ...
  http://cvja.co.za/archive/vol_28_issue_3_June.php
*  Chronic stable angina guidelines - is there an emerging international consensus? | The British Journal of Cardiology
... reduction in myocardial ischaemia, p=0.004). Indeed, the extent of myocardial ischaemia was a key determinant of the benefit ( ... sudden cardiac death, or all-cause mortality. Evidence from ACTION (A Coronary Disease Trial Investigating Outcome with ... cardioprotective properties can bridge the gap between nitrate use and effective management of stable angina and ischaemia. ... Data from COURAGE-PCI10 showed significantly greater reduction in myocardial ischaemia (where ischaemia is defined as ...
  https://bjcardio.co.uk/2012/08/chronic-stable-angina-guidelines-is-there-an-emerging-international-consensus/
*  Sports Participation and Sudden Cardiac Arrest - American College of Cardiology
Sudden cardiac death in the athlete: bridging the gaps between evidence, policy, and practice. Circulation 2012;125:2511-6. ... These triggers can include acute myocardial ischemia, abrupt hemodynamic changes, and increased sympathetic stimulation, all of ... Sudden deaths in young competitive athletes: analysis of 1866 deaths in the United States, 1980-2006. Circulation 2009;119:1085 ... Mortality and sudden death in pediatric left ventricular noncompaction in a tertiary referral center. Circulation 2013;127:2202 ...
  http://www.acc.org/latest-in-cardiology/articles/2016/06/28/07/06/sports-participation-and-sudden-cardiac-arrest
*  Cardiac Arrest | Circulation Research
... was the best predictor of early sudden death after myocardial infarction.47,48 Furthermore, the proposed benefit of N-3 fatty ... Calpain system and its involvement in myocardial ischemia and reperfusion injury. World J Cardiol. 2014;6:638-652. doi: 10.4330 ... but may be related to loss of optimum cross-bridge overlap (eg, starling forces) when the erectile effect of the vasculature is ... Roles in Sudden Cardiac Death. Finding the Rhythm of Sudden Cardiac Death: New Opportunities Using Induced Pluripotent Stem ...
  http://circres.ahajournals.org/content/116/12/2041.full
*  Obstructive hypertrophic cardiomyopathy - Explain Medicine
Sudden death [1],[4]. In hypertrophic cardiomyopathy there are extensive myocardial disarray in which numerous myocytes are ... myocardial bridging, decreased coronary perfusion pressure, obstruction to LV outflow, and decreased capillary myocardial fiber ... This can be occur due to myocardial ischemia. This may be due to small-vessel disease with decreased vasodilator capacity. ... MARON B. J., ROBERTS W. C., EPSTEIN S. E.. Sudden death in hypertrophic cardiomyopathy: a profile of 78 patients. Circulation [ ...
  http://www.explainmedicine.com/article/Cardiovascular/Obstructive-Hypertrophic-Cardiomyopathy
*  Heart failure post-myocardial infarction: a review of the issues | Heart
SCD-HeFT, sudden cardiac death in heart failure trial. *TACTICS TIMI 18, treat angina with Aggrastat and determine cost of ... involving the extent of myocardial damage at the time of the index event, recurrent ischaemia and the development of myocardial ... "bridge" to revascularisation by PCI, transplantation or even recovery. In some patients, LVADs will provide "destination" ... SCD-HeFT, sudden cardiac death in heart failure trial. *TACTICS TIMI 18, treat angina with Aggrastat and determine cost of ...
  http://heart.bmj.com/content/91/suppl_2/ii3
*  Ingela Schnittger, MD | Stanford Medicine Profiles
A myocardial bridge (MB) has been associated with ventricular arrhythmia and sudden death during exercise. QT dispersion (QTd) ... ULTRASONIC TISSUE CHARACTERIZATION - DETECTION OF ACUTE MYOCARDIAL ISCHEMIA IN DOGS CIRCULATION Schnittger, I., Vieli, A., ... Although it is general perception that myocardial bridges are normal variants, patients with myocardial bridges can present ... Stress testing identifies asymptomatic individuals at high risk for acute myocardial infarction or sudden cardiac death. ...
  https://med.stanford.edu/profiles/ingela-schnittger
*  Most recent papers in the journal Research in Cardiovascular Medicine | Read by QxMD
... myocardial infarction or sudden death. CASE PRESENTATION: A 32-year-old woman presented with edema of the upper and lower limbs ... ECMO was used as a bridge to lung transplantation. However, after prolonged resuscitation, he developed medullary ischemia and ... Myocardial Infarction Secondary to Inflammatory Myofibroblastic Tumor Obstruction of the Left Main: Treated With Primary PCI. ... have mentioned that coronary artery disease developing at early ages in patients with Turner syndrome causes sudden deaths. ...
  https://www.readbyqxmd.com/journal/49200
*  T-Wave Alternans and Human Ventricular Arrhythmias | JACC: Journal of the American College of Cardiology
2000) Electrophysiologic testing to identify patients with coronary artery disease who are at risk for sudden death. N Engl J ... 21) also suggest a transmural gradient in RPA, yet their recordings did not span the same myocardial region, so this needs ... In animals, spatially non-uniform RPA after premature beats, rapid pacing (20), or acute ischemia (18) might lead to discordant ... 21) provide important data to bridge this divide. In a small population of patients with ischemic and nonischemic ...
  http://www.onlinejacc.org/content/49/3/347
*  Spark-Induced Sparks As a Mechanism of Intracellular Calcium Alternans in Cardiac Myocytes | Circulation Research
RyR2 mutations linked to ventricular tachycardia and sudden death reduce the threshold for store-overload-induced Ca2+ release ... Spatial heterogeneity of calcium transient alternans during the early phase of myocardial ischemia in the blood-perfused rabbit ... Inoue M, Bridge JH. Ca2+ sparks in rabbit ventricular myocytes evoked by action potentials: involvement of clusters of L-type ... Pulsus alternans and T-wave alternans are associated with cardiac arrhythmias and sudden death, and calcium alternans has been ...
  http://circres.ahajournals.org/content/106/10/1582
*  Cardiac Literature, including Myocardial Infarction, arrthymias, tachycardia, and angina sub-cluster 63
BACKGROUND: Hypertrophic cardiomyopathy is considered to be the most common cause of exercise-related sudden death in young ... Concomitant idiopathic hypertrophic subaortic stenosis and disseminated myocardial bridging is an uncommon clinical entity with ... although its clinical manifestations are often similar to those of myocardial ischemia. This syndrome is possibly due to an ... Cardiovascular magnetic resonance (CMR) was performed for further assessment of myocardial function and presence of myocardial ...
  http://www.biomedsearch.com/cluster/1/Cardiac-Literature-including-Myocardial-Infarction-arrthymias-tachycardia-and-angina/sub-63-p9.html
*  Sulfonamide endothelin antagonists - Patent # 5965732 - PatentGenius
... and treatment of hepatoxicity and sudden death.. The compounds of this invention can also be formulated in combination with ... The term "alkylene" refers to a straight chain bridge of 1 to 5 carbon atoms connected by single bonds (e.g., --(CH.sub.2).sub. ... renal and cerebral ischemia and the like.. In addition, the compounds of this invention may also be useful as anti-arrhythmic ... agents; anti-anginal agents; anti-fibrillatory agents; anti-asthmatic agents; therapy for myocardial infarction; therapy for ...
  http://www.patentgenius.com/patent/5965732.html
*  Non-atherosclerotic coronary artery disease and sudden death in the young
Myocardial infarction associated with a myocardial bridge. Am Heart J. 1986 Apr;111(4):784-787. [PubMed] ... be suspected in young patients who have symptoms of ventricular arrhythmias without any overt signs and symptoms of ischaemia. ... Vasan RS, Bahl VK, Rajani M. Myocardial infarction associated with a myocardial bridge. Int J Cardiol. 1989 Nov;25(2):240-241. ... Myocardial bridges: morphological and functional aspects. Br Heart J. 1991 Nov;66(5):364-367. [PMC free article] [PubMed] ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC1025692/
*  Ventricular septal rupture caused by myocardial bridge, solved by interventional closure device.
Myocardial bridging is a common coronary anomaly, which is generally described as a benign phenomenon. However, a growing ... and sudden cardiac death (1). Research based on coronary angiography, a gold standard for diagnosing myocardial bridging, ... this wall segment showed characteristics typical of ischemia: hypokinesis, normal thickness, and delayed contrast ... pathologists find myocardial bridging in up to 80% of all examined hearts (1). The relevance of the limitation of myocardial ...
  http://www.biomedsearch.com/nih/Ventricular-septal-rupture-caused-by/23275329.html
*  GMS | GMS German Medical Science - an Interdisciplinary Journal | Electrocardiologic and related methods of non-invasive...
... and primarily focuses on His bundle recordings and detection of patients at high risk of sudden cardiac death after myocardial ... Different kinds of arrhythmias, particularly ischemia-associated ventricular arrhythmias could indicate myocardial ischemia and ... thereby altering heart rate variability and bridging autonomous nervous system and inflammation. Furthermore, a reduction of ... 14 from sudden arrhythmic death, 22 from sudden death and 34 from cardiac death. A combination of four HRV parameters from all ...
  http://www.egms.de/static/en/journals/gms/2010-8/000116.shtml
*  Clinical Applications of Stem Cells for the Heart | Circulation Research
... ischemia increases the risk of arrhythmias and sudden cardiac death. There is a clear need for new therapeutic strategies aimed ... and regional contractility in pigs with chronic myocardial ischemia9,72 The mechanisms how BMC injections enhance myocardial ... scarred myocardium in five patients with end-stage ischemic heart failure undergoing LV assist device implantation as a bridge ... Stem Cells for Myocardial Regeneration. Myocyte Death, Growth, and Regeneration in Cardiac Hypertrophy and Failure. Neural Stem ...
  http://circres.ahajournals.org/content/96/2/151
*  Screening for proximal coronary artery anomalies with 3-dimensional MR coronary angiography
Sudden deaths in young competitive athletes: analysis of 1866 deaths in the United States, 1980-2006. Circulation. 2009;119: ... Myocardial bridging of the LAD was observed in seven of our cases, which was only confirmed in one person by MDCTA as the other ... to detect local ischemia or arrhythmias [25]. If positive, a x-ray coronary angiography or scintigraphy can be performed. ... Participants with myocardial bridging were not offered MDCTA as it is a common incidental finding on CT and only very rarely ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2898111/
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
This approach is based on 90 min of myocardial ischemia, inducing large left ventricle infarction of the anterior, septal and ... sudden and unexpected death associated with epilepsy (SUDEP) 18. As with SE, the precise mechanisms mediating SUDEP are not ... He was successfully bridged to heart transplantation 5 months after receiving the device. This report highlights the TAH is ... with high efficacy and can protect patients from sudden cardiac death (SCD). However, inappropriate shocks may occur if ...
  https://www.jove.com/visualize/abstract/23675514/impact-shocks-on-mortality-patients-with-ischemic-or-dilated
*  An Overview of the Consequences of Distal Coronary Microembolization on Left Ventricular Function, Perfusion and Viability
M. J. Davies and A. C. Thomas, "Plaque Fissuring-The Cause of Acute Myocardial Infarction, Sudden Ischaemic Death, and ... and K. A. Reimer, "Myocardial Ischemia and Reperfusion," Monographs in Pathology, Vol. 37, 1995, pp. 47-80. ... J. L. Anderson, C. D. Adams, E. M. Antman, C. R. Bridges, R. M. Califf, D. E. Casey, Jr., W. E. Chavey, 2nd, F. M. Fesmire, J. ... "Sudden Coronary Death. Frequency of Active Coronary Lesions, Inactive Coronary Lesions, and Myocardial Infarction," Circulation ...
  http://www.scirp.org/journal/PaperInformation.aspx?paperID=3932
*  Amplified Transmural Dispersion of Repolarization as the Basis for Arrhythmogenesis in a Canine Ventricular-Wedge Model of...
Sudden death associated with short-QT syndrome linked to mutations in HERG. Circulation. 2004; 109: 30-35. ... Cardiac Repolarization: Bridging Basic and Clinical Sciences. Totowa, NJ: Humana Press; 2003: 497-506. ... Role of cardiac ATP-regulated potassium channels in differential responses of endocardial and epicardial cells to ischemia. ... Plasma adrenaline and noradrenaline in patients with acute myocardial infarction: relationship to ventricular arrhythmias of ...
  http://circ.ahajournals.org/content/110/24/3661