*  T7 RNA polymerase from Chimerx
is a serine/threonine phosphatase isolated from human ... the heterodimer of 60kDa (A) and 36kDa ... dephosphorylate the a- ... subunit of phosphorylase kinase. With ... substrate specificity and may play a regulatory ... ... Transcripts can be used as hybridization probes, templates for in vitro translation, substrates in RNA processing systems, or ...
  http://www.bio-medicine.org/biology-products/T7-RNA-polymerase-from-Chimerx-863-1/
*  PROTEAN II xi 2-D Cell from Bio-Rad
is a serine/threonine phosphatase isolated from human ... the heterodimer of 60kDa (A) and 36kDa ... dephosphorylate the a- ... subunit of phosphorylase kinase. With ... substrate specificity and may play a regulatory ... ...
  http://www.bio-medicine.org/biology-products/PROTEAN-II-xi-2-D-Cell-from-Bio-Rad-2104-1/
*  Rabbit Anti-ABAT Polyclonal Antibody, Unconjugated from Proteintech Group, Inc.
is a serine/threonine phosphatase isolated from human ... the heterodimer of 60kDa (A) and 36kDa ... dephosphorylate the a- ... subunit of phosphorylase kinase. With ... substrate specificity and may play a regulatory ... ...
  http://www.bio-medicine.org/biology-products/Rabbit-Anti-ABAT-Polyclonal-Antibody--Unconjugated-from-Proteintech-Group--Inc--4657-1/
*  Fast skeletal muscle transcriptome of the Gilthead sea bream (Sparus aurata) determined by next generation sequencing | BMC...
Protein phosphatase 1 catalytic subunit; PHKG, Phosphorylase b kinase gamma; PHK1-B, Phosphorylase kinase alpha-beta subunit; ... Rac-beta serine/threonine protein kinase 2; AKT3, Rac-beta serine/threonine protein kinase 3; ATG1, Serine/threonine-protein ... and insulin receptor substrate (IRS) (2). The only PI3K/Akt/mTOR pathway component that was not represented in the ... Serine threonine-protein phosphatase. Essential for cell division, and participates in muscle contractility and protein ...
  https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-13-181
*  Phosphoprotein Phosphatases Serine Threonine | China-Mainland | Sigma-Aldrich
Type 1 protein phosphatases (PP1) dephosphorylate the β-subunit of phosphorylase kinase and are inhibited by phospho-inhibitor- ... Prior to the knowledge of their sequence, phosphoserine/threonine phosphatases were classified on the basis of their substrate ... PP2C: Phosphoprotein phosphatase 2C. PPM: Phosphoprotein phosphatase M family. PPP: Phosphoprotein phosphatase P family. RIPP: ... PP: Phosphoprotein phosphatase. PP1: Phosphoprotein phosphatase 1. PP2A: Phosphoprotein phosphatase 2A. PP2B: Phosphoprotein ...
  http://www.sigmaaldrich.com/china-mainland/zh/technical-documents/articles/biology/rbi-handbook/intracellular-signaling-enzymes-receptors/phosphoprotein-phosphatases-serine-threonine.html
*  GeneAmplimer HIV-1 Control Reagents from Applied Biosystems
is a serine/threonine phosphatase isolated from human ... the heterodimer of 60kDa (A) and 36kDa ... dephosphorylate the a- ... subunit of phosphorylase kinase. With ... substrate specificity and may play a regulatory ... ...
  http://www.bio-medicine.org/biology-products/GeneAmplimer--HIV-1-Control-Reagents-from-Applied-Biosystems-3928-1/
*  Cyclophilin residues that affect noncompetitive inhibition of the protein serine phosphatase activity of calcineurin by the...
... assay to measure inorganic phosphate production using the enzyme purine ribonucleoside phosphorylase and the substrate N7- ... Cyclophilin residues that affect noncompetitive inhibition of the protein serine phosphatase activity of calcineurin by the ... but altered its ability to inhibit the serine phosphatase activity of calcineurin (CN). R69E was 13-fold less effective (Ki = ... The phosphoserine phosphatase reaction catalyzed by CN using unlabeled phosphoserine RII19 peptide was coupled to a continuous ...
  https://www.ncbi.nlm.nih.gov/pubmed/8117697
*  HPr kinase/phosphorylase, C-terminal (IPR011104) | InterPro | EMBL-EBI
This entry represents the C-terminal kinase domain of Hpr Serine/threonine kinase (HprK/P). HprK/P is a bifunctional histidine- ... Structure of the full-length HPr kinase/phosphatase from Staphylococcus xylosus at 1.95 A resolution: Mimicking the product/ ... substrate of the phospho transfer reactions.. Proc. Natl. Acad. Sci. U.S.A. 99 3458-63 2002 ... HPr kinase/phosphorylase, C-terminal (IPR011104). Short name: Hpr_kin/Pase_C ...
  http://www.ebi.ac.uk/interpro/entry/IPR011104
*  anti-PPP1R3C antibody | Rabbit PPP1R3C Polyclonal Antibody-NP 005389.1
Molecular Function: protein binding; protein serine/threonine phosphatase activity; protein phosphatase binding. Biological ... By interacting with different regulatory subunits, PP1 is directed to different parts of the cell, to different substrates, or ... Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases ... Protein phosphatase 1 regulatory subunit 3C UniProt Synonym Protein Names Protein phosphatase 1 regulatory subunit 5; PP1 ...
  https://www.mybiosource.com/prods/Antibody/Polyclonal/PPP1R3C/datasheet.php?products_id=9413679
*  Protein phosphatase 1 - Wikipedia
Protein phosphatase 1 (PP1) belongs to a certain class of phosphatases known as protein serine/threonine phosphatases. This ... This binding to phosphorylase a prevents any phosphatase activity of PP1 and maintains the glycogen phosphorylase in its active ... Also, when other substrates become phosphorylated by protein kinase A, they can bind to the catalytic subunit of PP1 and ... Phosphorylase a serves as a glucose sensor in liver cells. When glucose levels are low, phosphorylase a in its active R state ...
  https://en.wikipedia.org/wiki/Protein_phosphatase_1
*  B for Biology: Signal Transduction Pathway - The cAMP Pathway
These phosphatases remove the phosphate group from tyrosine or serine or threonine residues in the substrate proteins thereby ... phosphorylase kinase. This kinase is phosphorylated on serine residue by PKA; which then activates glycogen phosphorylase. The ... Lets make it more clear by taking the example of protein kinase A. The serine residues of the target proteins (phosphorylase ... which are phosphorylated by PKA are usually dephosphorylated by phosphatase called as protein phosphatase 1. Thus, the levels ...
  http://namrataheda.blogspot.in/2013/02/signal-transduction-pathway-camp-pathway.html
*  KEGG SSDB Best Search Result: mcj:MCON 3086
bpsp:AH67_00360 maltodextrin phosphorylase K00688 817 103 ( -) 29 0.365 74 -, 1 ctae:BGI42_03790 serine phosphatase RsbU, ... cet:B8281_16485 ABC transporter substrate-binding prote K02027 457 117 ( -) 33 0.306 121 ,-, 1 bcm:Bcenmc03_4466 peptidase S8 ... sesp:BN6_61310 Protein serine/threonine phosphatase 461 104 ( -) 30 0.308 120 -, 1 vbr:A6E01_09525 thioredoxin-dependent thiol ... bstg:WT74_17445 sugar ABC transporter substrate-binding K02058 356 104 ( -) 30 0.375 40 ,-, 1 ceu:A7L45_19960 excinuclease ABC ...
  http://www.kegg.jp/ssdb-bin/ssdb_best?org_gene=mcj:MCON_3086
*  Dephosphorylation - Wikipedia
Phosphatase Phosphorylation FISCHER, EH; KREBS, EG (Sep 1955). "Conversion of phosphorylase b to phosphorylase a in muscle ... and substrate specificities of phosphoprotein phosphatase(s) from rabbit liver". The Journal of Biological Chemistry. 251 (16 ... Krebs and Edmond Fischer used radiolabeled ATP to determine that phosphate is added to the serine residue of phosphorylase to ... Tau dephosphorylation is catalysed by protein phosphatase-2A and phosphatase-2B. Deficiency or modification of one or both ...
  https://en.wikipedia.org/wiki/Dephosphorylation
*  Cells | Free Full-Text | The Challenge of Producing Ubiquitinated Proteins for Structural Studies | HTML
It has different effects on the target protein substrate, i.e., it can trigger the degradation of the protein in the proteasome ... used to explore the effect of ubiquitination on calmodulin-mediated regulation of phosphorylase kinase and protein phosphatase ... It has different effects on the target protein substrate, i.e., it can trigger the degradation of the protein in the proteasome ... The solvent-accessible C118 of Ras was mutated to serine to prevent unwanted modifications, while the other two cysteines in ...
  http://www.mdpi.com/2073-4409/3/2/639/htm
*  What Makes a Cancer Cell a Cancer Cell? - Holland-Frei Cancer Medicine - NCBI Bookshelf
Protein Phosphatases. Although it has been known for a long time that protein phosphatases play a regulatory role in certain ... The substrates of these kinases include transcription regulatory factors, such as those linked to mitogenic signaling pathways ... They contain O-linked glycans (serine- and threonine-linked) of various lengths and structures, depending on the tissue type in ... cellular metabolic functions, for example, in the activation-inactivation steps for glycogen synthase and phosphorylase, it has ...
  https://www.ncbi.nlm.nih.gov/books/NBK12516/
*  Propagating Differential Gene Expression in Protein Interaction Networks
Based on their substrate specificity, these phosphatases can be divided into several groups e.g. serine/threonine protein ... Serine Threonine protein phosphatases; F) glycogen phosphorylase; G) neuronal voltage-gated/dependent calcium channel neuronal ... Cluster B, E and F are related to protein phosphatases, which dephosphorylate their substrates thereby often abrogating the ... Protein phosphatase-2A is a target of epigallocatechin-3-gallate and modulates p53-Bak apoptotic pathway Jichao Qin, Hi-Ge Chen ...
  http://werner.yellowcouch.org/Papers/proteffect/index.html
*  Mammalian Receptor Proteins; Related Reagents and Methods - Patent application
For example, these receptors should mediate phosphatase or phosphorylase activities, which activities are easily measured by ... The substrates may be, e.g., solid resin beads or sheets of plastic. [0123]Protein fragments may be joined to other materials, ... serine, threonine; lysine, arginine; and phenylalanine, tyrosine. Homologous amino acid sequences are intended to include ... Substrates may be identified, or conditions for enzymatic activity may be assayed by standard methods, e.g., as described in ...
  http://www.patentsencyclopedia.com/app/20100261273
*  Protein phosphatase - Wikipedia
Many phosphatases are promiscuous with respect to substrate type, or can evolve quickly to change substrate. An alternative ... The major serine/threonine-specific folds are PPM (PP2C) and PPPL (PPP). The only known histidine phosphatases is in the PHP ... glycogen phosphorylase, and glycogen synthase. This leads to phosphorylase kinase and glycogen phosphorylase's becoming ... Phosphatases can be subdivided based upon their substrate specificity. Protein Ser/Thr phosphatases were originally classified ...
  https://en.wikipedia.org/wiki/Protein_phosphatase
*  Gene Report for G00001442 - Genes2Cognition Neuroscience Research Programme
The Tat-associated protein phosphatase (TAPP) is related to the serine/threonine, type 1, protein phosphatase (PP1) family. ... Using substrate screening in various tissues, we uncovered two major substrates, p130 and p85, for MRCKalpha-kinase. p130 is ... While GADD34 inhibited PP1-catalyzed dephosphorylation of phosphorylase a, the GADD34-bound PP1 was an active eIF-2alpha ... We observed that the protein HOX11 interacted with protein serine-threonine phosphatase 2A catalytic subunit (PP2AC), as well ...
  http://www.genes2cognition.org/db/Gene/G00001442
*  KEGG BRITE: KEGG Orthology (KO) - Pelodiscus sinensis (Chinese soft-shelled turtle)
... serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] K06269 PPP1C; serine/threonine-protein phosphatase PP1 ... 102463626 IRS1; insulin receptor substrate 1 102457842 IRS4; insulin receptor substrate 4 106731934 insulin receptor substrate ... 102451702 protein phosphatase 1 regulatory subunit 3C-B-like 102455436 PHKG1; phosphorylase kinase catalytic subunit gamma 1 ... serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] K06269 PPP1C; serine/threonine-protein phosphatase PP1 ...
  http://www.genome.jp/kegg-bin/get_htext?pss00001+102462946
*  Overview of Protein Phosphorylation - Current Protocols
Mutational analysis of a ser/thr phosphatase. Identification of residues important in phosphatase substrate binding and ... Protein (serine, threonine) phosphate phosphatases. Methods Enzymol. 107:102‐130. Shenolikar, S. and Nairn, A.C. 1991. Protein ... Enzymatic conversion of phosphorylase a to b. J. Biol. Chem. 158:321‐345. ... Protein serine/threonine phosphatases: New avenues for cell regulation. Annu. Rev. Cell Biol. 10:55‐86. ...
  http://www.currentprotocols.com/WileyCDA/CPUnit/refId-ps1301.html
*  2nym - Proteopedia, life in 3D
Hsu W, Zeng L, Costantini F. Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a ... PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B ... The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of ... Categories: Human , Phosphoprotein phosphatase , Chao, Y , Chen, Y , Jeffrey, P D , Lin, Z , Shi, Y , Xing, Y , Xu, Y , Heat ...
  http://proteopedia.org/wiki/index.php/2nym
*  Protein phosphorylation - Wikipedia
... glycogen phosphorylase by assisting in the transfer of the γ-phosphoryl group of ATP to a serine residue on phosphorylase b. ... Protein kinases and phosphatases work independently and in a balance to regulate the function of proteins. The amino acids most ... Holt LJ, Tuch BB, Villén J, Johnson AD, Gygi SP, Morgan DO (2009). "Global Analysis of Cdk1 Substrate Phosphorylation Sites ... The signaling capabilities of FGFR1 at the serine 777 site can be weakened by phosphorylation. Serine 1047 and serine 1048 have ...
  https://en.wikipedia.org/wiki/Protein_phosphorylation
*  KEGG SSDB Best Search Result: ptr:462413
llu:AKJ09_05697 Serine/threonine phosphatase PPP 1135 100 ( -) 29 0.312 64 -, 1 lpe:lp12_0062 multidrug resistance protein 392 ... glz:GLAREA_04696 MFS general substrate transporter 850 101 ( 0) 29 0.314 51 -, 2 gox:GOX1050 dTDP-4-dehydrorhamnose reductase ... fsc:FSU_2626 glycogen phosphorylase K00688 824 100 ( -) 29 0.321 81 -, 1 fsu:Fisuc_2097 glycogen/starch/alpha-glucan ... slau:SLA_2363 serine or threonine protein kinase K14949 693 114 ( -) 32 0.310 84 -, 1 sld:T261_5397 Serine/threonine-protein ...
  http://www.kegg.jp/ssdb-bin/ssdb_best?org_gene=ptr:462413
*  Phosphorylase kinase - Wikipedia
... to the substrate serine. Phosphorylase kinase is a 1.3 MDa hexadecameric holoenzyme, though its size can vary somewhat due to ... When the cell needs to stop glycogen breakdown, PhK is dephosphorylated by protein phosphatases 1 and 2, returning the α and β ... Phosphorylase kinase (PhK) is a serine/threonine-specific protein kinase which activates glycogen phosphorylase to release ... 1997). "The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition". EMBO J. 16 ( ...
  https://en.wikipedia.org/wiki/Phosphorylase_kinase