Anti-fibrotic effects of phenolic compounds on pancreatic stellate cells | BMC Complementary and Alternative Medicine | Full...
... curcumin and resveratrol significantly suppressed the mRNA and protein levels of several fibrotic mediators namely alpha-smooth ... As natural polyphenols had been largely applied in complementary therapies in the past decade, in this study, we aimed to ... The testing phenolic compounds of this study have been reported to be well absorbed by the human bowel; however, their ... a large amount of ECM proteins and various kinds of cytokines and/or growth factors . It is believed that the PSCs are ...https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-015-0789-y
Protocols and Video Articles Authored by Gaoqing Yang
In this study, the interactions between the HEV ORF3 protein and human proteins were investigated using a stringent, high- ... but there are not many detailed studies on the sex, age, subtypes and locations of large series. This study was a retrospective ... Heterotrimeric G Proteins Serve As a Converging Point in Plant Defense Signaling Activated by Multiple Receptor-like Kinases ... The data obtained in the study suggests that the decorin GAG chain has a small or a limited number of sequences. ...https://www.jove.com/author/Gaoqing_Yang
CREB-binding protein/p300 are transcriptional coactivators of p65. Proc Natl Acad Sci U S A 1997;94:2927-32. ... Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines. Oncogene 2001;20:7597-609. ... This is in line with the results of a previous study, in which deacetylation of lysine 310 of p65 led to Set9-mediated ... p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing ...http://mct.aacrjournals.org/content/10/9/1644
US5962415A - Compositions comprising a peptide inhibitor of nuclear protein translocation and an immunosuppressant and methods...
Novel compositions of immunosuppressants, such as cyclosporin, and polypeptide inhibitors of cytoplasmic protein nuclear ... Receptor protein for human B cell stimulatory factor-2 Bretscher et al. 1997. Ezrin: a protein requiring conformational ... NF-κB is composed of several different subunits including p65, p50, c-rel p52 and p105. Recent studies suggest that distinct NF ... and Human Retrovirus 11:885. Proviral DNA content (gag) was measured using polymerase chain reaction analysis as described in ...https://patents.google.com/patent/US5962415?oq=ascentive
Protocols and Video Articles Authored by Jing Huang (Translated to Portuguese)
... including the μ-opioid receptor, interact with G-proteins and other proteins via their intracellular face as required for ... B. Jun, 2016 , Pubmed ID: 27299801 We have studied the structure of (Ala)5, a model unfolded peptide, using a combination of 2D ... Human CD8+ T Cells Mediate Protective Immunity Induced by a Human Malaria Vaccine in Human Immune System Mice Vaccine. Aug, ... Several recent large-scale genome-wide association studies (GWAS) have identified HLA-I, HLA-II, CXCR5, ETS1, LPP and NCOA1 ...https://www.jove.com/author/Jing_Huang?language=Portuguese
Protocols and Video Articles Authored by Jing Huang
Quantitative Phase Imaging Study of Dormant and Active Human Cancer Cells' ... including the μ-opioid receptor, interact with G-proteins and other proteins via their intracellular face as required for ... B. Jun, 2016 , Pubmed ID: 27299801 We have studied the structure of (Ala)5, a model unfolded peptide, using a combination of 2D ... Human CD8+ T Cells Mediate Protective Immunity Induced by a Human Malaria Vaccine in Human Immune System Mice Vaccine. Aug, ...https://www.jove.com/author/Jing_Huang
Patente US6025194 - Nucleic acid sequence of senescence asssociated gene - Google Patentes
Isolated, purified, and recombinant nucleic acids and proteins corresponding to the human GC6 gene and its mRNA and protein ... products, as well as peptides and antibodies corresponding to the GC6 protein can be used to identify senescent cells, ... Human gene GC6 is expressed more abundantly in senescent cells than young cells. ... kinase H69011 211285 sno oncogene H66704 211864 TNF receptor II associated protein (TRAF2) H69474 212414 retinoic acid receptor ...http://www.google.es/patents/US6025194
Other | Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors
The proto-oncogene c-kit, localized to human chromosome 4, encodes a transmembrane receptor, CD117/c-kit, belonging to the ... However, our study revealed a large and well defined pool of APCs with positive staining for HAM 56, CD68, S-100 and CD1a ... 21 Myc protein take part in oncogenesis in a multitude of tumors by a genuine variety of different systems, including raising ... p65), RelB, NF-B1 (p50/p105), and NF-B2 (p52/p100).31 Currently, a couple of zero spontaneous animal choices for MCL, although ...http://researchreport-digital.com/category/other/
JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Proteomic analyses of human, rat, mouse, and chick eCSF have identified many proteins that may be necessary for CSF function. ... METHODS: Transgenic silkworm technology was applied for obtaining a large amount for recombinant soluble GM-CSF receptor alpha ... Studies applying this human surgical wound bioassay have found no correlations between wound and serum cytokine concentrations ... nuclear translocation of the p65 subunit of NF-κB (p65), and secretion of the hallmark proinflammatory cytokine, tumor necrosis ...https://www.jove.com/visualize/abstract/25062013/granulocyte-colony-stimulating-factor-attenuates-oligomeric-amyloid
Brain Infection by Neuroinvasive but Avirulent Murine Oncornaviruses - PDF
Human Immunodeficiency Virus type 1 (HIV-1) p24 / Capsid Protein p24 ELISA Pair Set Human Immunodeficiency Virus type 1 (HIV-1 ... Rabbit Polyclonal antibody to NFkB p65 (v-rel reticuloendotheliosis viral oncogene homolog A (avian)) Datasheet GeneTex, Inc : ... nonstructural proteins Why would you want to study proteins associated with viruses or virus infection? Receptors Mechanism of ... Despite the use of the same receptor by both viruses in vivo (6), the envelope proteins of FrCas E and FB29 have only 75% ...http://healthdocbox.com/Aids_and_Hiv/65517162-Brain-infection-by-neuroinvasive-but-avirulent-murine-oncornaviruses.html
Sensitivity of leukemic T-cell lines to arsenic trioxide cytotoxicity is dependent on the induction of phosphatase B220/CD45R...
T-cell lines for their marked differences in As2O3 sensitivity over a large range of doses (1 to 20 μM). Differences in redox ... We selected human (Jurkat, Jurkat variant J45.01, HPB-ALL) and mouse (EL-4, BW5147, L1210) ... In the present study, we determined the sensitivity to As2O3-induced cytotoxicity and growth inhibition of human (Jurkat and ... Takayama S, Reed JC, Homma S: Heat-shock proteins as regulators of apoptosis. Oncogene. 2003, 22: 9041-9047. 10.1038/sj.onc. ...https://molecular-cancer.biomedcentral.com/articles/10.1186/1476-4598-13-251
October 2016 - New β-secretase inhibitors for treatment of Alzheimer's disease
CD45 is a protein tyrosine phosphatase receptor that is critically important for T and B cell antigen receptor-mediated ... In this study we examined the function(s) of syndecan-4 in regulating. In this study we examined the function(s) of syndecan-4 ... Human T-cell leukemia computer virus type 1 (HTLV-1) causes adult T-cell. Human T-cell leukemia computer virus type 1 (HTLV-1) ... The lack of either Ku WZ4002 antigen or DNA-PK large catalytic subunit (DNA-PKcs) contributes to high radiosensitivity ...http://healthyguide.info/2016/10/