Randomised controlled trial protocol for the PROTECT-CS Study: PROTein to Enhance outComes of (pre)frail paTients undergoing...
51 A sample size of 150 patients (75 in each group) will allow for an overall drop-out rate of 15% (n=22) while maintaining a ... By using patient collaboration, we were able to design a study supported by patients for patients. The patient collaborative ... Study intervention. Study participants. All patients consenting to the study will be randomly allocated to either a protein or ... The PROTECT-CS Study is a patient/researcher collaborative study, involving two Canadian centres. The study is a double-blinded ...
Investigating efficacy of "microbiota modulation of the gut-lung Axis" combined with chemotherapy in patients with advanced...
Recent studies have shown a significant relationship between the gut-lung axis microecology and malignant tumors. Intestinal ... especially in patients with NSCLC without EGFR, ALK, and ROS gene mutations. The prognosis of lung cancer is poor, and the ... considering the drop-out rate of 20%, it was planned to require 90 cases per group. The sample is 180 cases. ... Men should agree to patients who must use contraception during the study period and within 6 months after the end of the study ...
Effect of dexamethasone in patients with ARDS and COVID-19 (REMED trial)-study protocol for a prospective, multi-centre, open...
The study will be conducted in the intensive care units (ICUs) of ten university hospitals in the Czech Republic. We aim to ... Patients will be randomised in a 1:1 ratio into one of the two treatment arms. The following stratification factors will be ... In patients with COVID-19 pneumonia in need of oxygen therapy or mechanical ventilation, dexamethasone 6 mg per day is ... The long-term outcomes of this study are to assess long-term consequences on mortality and quality of life at 180 and 360 days ...
Growth and recurrence of colorectal polyps: a double-blind 3-year intervention with calcium and antioxidants
The study did not find an overall effect on polyp growth. Our data, however, may support a protective role of calcium and ... Patient Compliance * Patient Dropouts * Prospective Studies * Time Factors * Vitamin A / administration & dosage ... Results: 87-91% of the patients attended the annual endoscopic follow-up investigations, and 19% of the patients dropped out of ... This has been supported by animal experimental studies, case control and cohort studies. ...
Comparison of naproxen and acetaminophen in a two-year study of treatment of osteoarthritis of the knee
Sixty-two patients completed the 2-year study. Among these patients, radiographic progression was similar in the 2 treatment ... Comparison of naproxen and acetaminophen in a two-year study of treatment of osteoarthritis of the knee Arthritis Rheum. 1993 ... Withdrawal from the trial due to lack of drug efficacy was slightly more frequent among patients in the ACT group (22% versus ... Methods: One hundred seventy-eight patients with OA of the knee were enrolled in a 2-year prospective, controlled, double-blind ...
December 2002 - The CenterWatch Monthly : Volume 9, Issue 12, December 2002
... career and training opportunities for patients and professionals. ... Dropout rates are highest in phase II/III and lowest in post- ... approval studies. Given its impact on delaying development cycle time and increasing project costs, biopharmaceutical companies ... Minimizing Volunteer Dropout. A CenterWatch analysis of completion records provided by IRBs reveals that an estimated 26% of ... Recently, several major SMOs have diversified their operations to include patient recruitment, pharmacogenomic and traditional ...
Self-Rated Physical Health and Unmet Healthcare Needs among Swedish Patients in Opioid Substitution Treatment
... has been sparsely studied.,i, Aim,/i,. To assess OST patients’ self-rated physical health and healthcare seeking ... Patients’ frequent visits to the OST clinics offer a unique opportunity to build a base for easily accessible on-site ... However, this field is still unexplored, with only a few studies focusing on general health within this population. The first ... Barriers surrounding the healthcare system seem to hinder patients to seek help through conventional healthcare, even after ...
Seeing People Succeed Too Well Might Discourage You From Trying Too Hard
A recent study suggests that being convinced your peers are especially talented may worsen your own performance. ... Over 20% Of COVID Patients Treated With Paxlovid Suffer Virologic Rebound: Study. Over 20% of patients taking Nirmatrelvir- ... the duo found people who evaluated excellent essays were more likely to drop out afterwards than those who simply looked over ... Gene Silencing Technology Offers Fresh Hope For Alzheimers Patients. The genetic study showed promising results in "silencing ...
Novel Intervention Markedly Slows Cognitive Decline in MCI
Goal setting and action plans help prevent memory and functional decline in African American patients with mild cognitive ... However, men were more likely to drop out.. In light of this new study, clinicians might want to consider getting patients to ... Petersen said he found the study "intriguing" and suggested that a larger study should be carried out in this population. ... The study was published online September 10 in JAMA Neurology.. Higher Rate of Dementia African Americans have double the rate ...
Heart Disease | The Asian Age
People with mental illness likely to drop out of cardiac rehab. Researchers find one in five cardiac rehab patients suffers ... Studies reveal that strong link found between level of depression and heart disease, stroke. ... Omega-3 protects heart against diseases without elevating prostate cancer risk, finds study. ...
Handle with Care: The Impact of Using Java Applets in Web-Based Studies on Dropout and Sample Composition - WebSM
Patient preference: a comparison of electronic patient-completed questionnaires with paper among cancer...; 2016; Martin, P.; ... Title Handle with Care: The Impact of Using Java Applets in Web-Based Studies on Dropout and Sample Composition ... we analyzed whether using a Java applet produces dropout and distortion of demographics in the final sample. Dropout was ... In web-based studies, web browsers are used to display online questionnaires. If an online questionnaire relies on non-standard ...
Pretreatment Out-of-Pocket Expenses for Presumptive Multidrug-Resistant Tuberculosis Patients, India, 2016-2017 - Volume 26,...
In our study, no patients reported school dropouts or separation in families. None of the patients reported selling assets such ... The median total pretreatment out-of-pocket expense incurred by patients in our study is similar to that found in a study in ... We included 40 of the 63 registered patients in the study. Median (IQR) age of participants was 39 (29-50) years. Most patients ... school dropouts, loans, and money borrowed) (Appendix). Of the 40 MDR TB patients, the 16 who were admitted during the study ...
Psychotherapy discontinuation - Wikipedia
But the same patients might be considered non-completes in another study. Patient dropout is associated with numerous problems ... Further, socioeconomic status has been linked to client dropout, where poorer patients drop out more frequently. Environmental ... Psychotherapy discontinuation, also known as unilateral termination, patient dropout, and premature termination, is a patients ... there are different factors associated with patient dropout that are worth identifying. There are several meta-analysis studies ...
Randomised controlled trial of graded exercise in patients with the chronic fatigue syndrome | The BMJ
... drop out.. In all, 167 outpatients were screened for the study. All had been referred to a chronic fatigue clinic in a general ... Only five patients declined the study and five were too ill to attend as outpatients. The same result in patients who crossed ... patients who completed exercise treatment were working or studying at least part time compared with 26 (39%) of all 66 patients ... Patients and methods. Patients met the Oxford criteria for the chronic fatigue syndrome.16 In addition, by using the structured ...
Olfactory shifts linked to postpartum depression | Scientific Reports
The present study addresses this research gap by assessing differences in olfactory abilities between 39 depressed mothers, who ... The present study is the first to assess olfactory abilities in patients with PPD. Findings from the study have two important ... The primary reason of dropouts given by the participants was lack of time to attend the experiments. ... To date, most sensory studies of MDD patients suggest that depressed patients perceive "unpleasant" odours to be significantly ...
Frontiers | Symptoms of anxiety and depression associated with steroid efficacy and clinical outcomes in patients with...
Future studies are needed to explore whether interventions for anxiety and depression will improve their response to ... Conclusion: IBD patients with anxiety/depression symptoms were at a higher risk of developing steroid resistance and IBD- ... Results: A total of 325 IBD patients were enrolled, 118 of whom were treated with corticosteroids, 88 with azathioprine/6- ... Method: This was a prospective longitudinal observational study. Hospital Anxiety and Depression Scale was used to assess ...
Esketamine-based opioid-free anaesthesia alleviates postoperative nausea and vomiting in patients who underwent laparoscopic...
The study was designed as a prospective, randomized, controlled, multicentre trial. A total of 278 patients were enrolled; ... The aim of this study was to investigate whether the application of OFA by using esketamine in intraoperative analgesia could ... participants were nonsmoking female patients aged 18-50 years and scheduled for laparoscopic appendectomy or cholecystectomy, ... Dropout criteria. The dropout criteria are as follows: (1) withdrawal of consent by the participants or their legal ...
Safinamide improves responder rates in fluctuating Parkinson's patients in Phase III study
... presented results from SETTLE Phase III study with safinamide at the 17th International Congress of Parkinsons disease and ... 484 patients completed the trial; the drop-out rate was similar in both treatment groups (approx. 12%). The most commonly ... Safinamide improves responder rates in fluctuating Parkinsons patients in Phase III study. *Download PDF Copy ... Patients who were experiencing a minimum of one and a half hours of OFF time during the day were randomized equally to ...
IJERPH | Free Full-Text | Is a Mask That Covers the Mouth and Nose Free from Undesirable Side Effects in Everyday Use and Free...
For a quantitative evaluation, 44 mostly experimental studies were referenced, and for a substantive evaluation, 65 ... In the dropouts of the study, dizziness (57%) and headaches were also often recorded. In the mask-tolerant COPD patients, ... Elderly, high-risk patients with lung disease, cardiac patients, pregnant women or stroke patients are advised to consult a ... Thirty-one of these studies were experimental (70%), and 13 studies were data collection studies in the sense of simple ...
Keyword: cannabis
The study involved testing 22 adult patients with severe Tourette symptoms. In the double-blind study,... ... Half of U.S. residents have tried marijuana, and 17% currently smoke weed - both new highs since the tune-in drop-out 1960s, a ... A Columbia University study has found that teens who use cannabis recreationally are two to four times as likely to develop ... Clinical study: Medicinal cannabis is a life-changing treatment for people with Tourette syndrome (Oral THC or CBD both ...
Childhood-Onset Schizophrenia Workup: Approach Considerations, MRI or CT scanning, EEG
Predictors of treatment response and drop out in the Treatment of Early-Onset Schizophrenia Spectrum Disorders (TEOSS) study. ... Vinokur D, Levine SZ, Roe D, Krivoy A, Fischel T. Age of onset group characteristics in forensic patients with schizophrenia. ... Prospective study of peer victimization in childhood and psychotic symptoms in a nonclinical population at age 12 years. Arch ... Longitudinal study of neurological soft signs in first-episode early-onset psychosis. J Child Psychol Psychiatry. 2012 Mar. 53 ...
Treatment of eating disorders in child and adolescent psychi... : Current Opinion in Psychiatry
... which is higher than that in most studies on adolescent CBT and FBT. The high drop-out rate was 30% in this study. ... In the well known study by Lock et al.[14], which compared AFT with FBT, significantly more patients in the FBT group achieved ... A systematic review by Madden [12] evaluated five studies, including three studies with adolescents. Two of the studies ... In a recent study by Schmidt and coworkers, significantly more patients treated faster at the specialist service had normalized ...
New ophthalmic dual-viscoelastic device in cataract surgery: a comparative study | BMJ Open Ophthalmology
All recruited patients completed the study after enrolment. There were no dropouts. Unexpected eye examination findings and ... Results The study enrolled 127 patients. Randomisation assigned 50 eyes of as many patients to each arm of the study. The ... The study included patients having cataract surgery and willing to adhere to the study protocol. All patients had a full ... One eye of each patient was evaluated in the study. A total of 127 patients (127 eyes) were assessed for study eligibility ...
Safety and patients' satisfaction of transcutaneous Supraorbital NeuroStimulation (tSNS) with the Cefaly® device in headache...
The objective of this study was to assess the satisfaction with the Cefaly® device in 2,313 headache sufferers who rented the ... tSNS with is a safe and well-tolerated treatment for migraine headaches that provides satisfaction to a majority of patients ... Moreover, there were no side effects or drop-outs due to device-related adverse events. ... 59 patients) and it was 3.24% (40 patients) in the subgroup of satisfied patients. Five patients reported more than one AE, one ...
The relationship between resting-state functional connectivity, antidepressant discontinuation and depression relapse |...
Patients were assessed a second time either before or after discontinuation of the antidepressant, and followed up for six ... 29 patients went on to relapse and 38 remained well. The seed-based analysis showed that discontinuation resulted in an ... 44 healthy controls (age: 33.8 (10.5), 73% female) and 84 patients (age: 34.23 (10.8), 80% female) were included in the ... Further seed-based analyses, however, failed to reveal differences in functional connectivity between patients and controls, ...
Frontiers | Probiotic Properties of Bifidobacterium longum KABP042 and Pediococcus pentosaceus KABP041 Show Potential to...
Finally, an exploratory, observational, pilot study involving 36 infants diagnosed with at least one FGID (infant colic and/or ... In this study, we have investigated the probiotic potential of the strains Bifidobacterium longum KABP042 and Pediococcus ... In this study, we have investigated the probiotic potential of the strains Bifidobacterium longum KABP042 and Pediococcus ... Forty-three patients were screened and 36 who satisfied inclusion and exclusion criteria were enrolled in the study. Infants ...
Full evidence summary | Orthostatic hypotension due to autonomic dysfunction: midodrine | Advice | NICE
Dropout from the study by Low et al. (1997) was higher in the midodrine arm (23/82, 28.0%) than in the placebo arm (9/89, 10.1 ... Patients who dropped out may have had less improvement in symptoms. Both of the key studies discussed in this evidence summary ... However, only 43/135 patients had orthostatic hypotension, and the observational nature of the study and the lack of a control ... One larger study (n=87) was published in German and could not be assessed. Also, because of differences between the studies in ...
Hepatocellular Adenoma (Hepatic Adenoma) Imaging: Practice Essentials, Computed Tomography, Magnetic Resonance Imaging
T1-weighted out-of-phase magnetic resonance image in a patient with von Gierke disease (same patient as in the following image ... In this study, CEUS allowed a correct diagnosis in more than 80% of focal liver lesions and led to a change in the diagnostic ... Lesions such as FNH drop out almost as much as healthy liver tissue; however, some hepatic adenomas and some well- ... T1-weighted out-of-phase magnetic resonance image in a patient with von Gierke disease (same patient as in the following image ...