*  Patent US5066789 - Targeting substance-diagnostic/therapeutic agent conjugates having Schiff ... - Google Patents
Targeting substance-diagnostic/therapeutic agent conjugates joined by stabilized Schiff base or hydrazone linkages are ... Ribosomal inactivating proteins (RIPs) are naturally occurring protein synthesis inhibitors that lack translocating and cell- ... Biotin, avidin, proteins corresponding to known cell surface receptors (including low density lipoproteins, transferrin, ... are treated with a reagent (for instance, iminothiolane) that adds free sulfhydryl groups to the targeting substance. The ...
  http://www.google.com/patents/US5066789?dq=5,832,511
*  Patent US7482173 - Method for attachment of silylated molecules to glass surfaces - Google Patents
Also provided are compounds, devices, and kits for modifying surfaces such as glass surfaces. ... of silylated molecules such as silylated oligonucleotides or proteins onto unmodified surfaces such as a glass surface is ... effector and receptor molecules, enzyme cofactor and enzymes, and enzyme inhibitors and enzymes. Other specific binding members ... peptides comprising a tumor-specific epitope, cells, cell-surface molecules, microorganisms, fragments, portions, components or ...
  http://www.google.com/patents/US7482173?dq=5,890,152
*  US20080292618A1 - Intranuclear protein transduction through a nucleoside salvage pathway - Google Patents
... wherein the conjugate can be transported into a cell or into the nucleus of a cell via a cellular nucleoside transport pathway ... Further provided are methods of delivering a conjugate molecule to a target cell expressing a nucleoside transport pathway, ... The receptor that interacts with a ligand can be present on the surface of a cell or can alternately be an intercellular ... Alternatively, molecules such asamino-sulfhydryl cross-linking reagents which are cleavable under mildly acidic conditions may ...
  https://patents.google.com/patent/US20080292618A1/en
*  Synthesis and biochemical evaluation of benzyl propargyl ethers as inhibitors of 5-lipoxygenase
Interactions of cells with extracellular matrix (ECM) are mediated through specific cell surface receptors, belonging to the ... Keywords: Sulfolobus acidocaldarius, E. coli, RNase A, Archaeal ribosomes, Polyamines, Sulfhydryl reagents, Structural ... Structure-function relationships of biomolecules, protein-protein and protein-DNA interactions, protein folding, mechanisms, ... Molecular mass is the mass of one molecule of a substance. ... min-1 mg protein-1, respectively, whereas KM values were 33.3 m ...
  http://www.niscair.res.in/ScienceCommunication/ResearchJournals/rejour/ijbb/ijbb2k7/ijbb_feb07.asp
*  Patent US7737252 - Peptide-based compounds - Google Patents
... in particular the αvβ3 integrin receptor. Such contrast agents may thus be used for diagnosis of for example malignant diseases ... specifically the invention relates to the use of such peptide-based compounds used as targeting vectors that bind to receptors ... Angiogenesis is accompanied by characteristic changes in endothelial cells and their environment. The surface of these cells is ... heterobifunctional cross-linking reagents such as those listed in the Pierce Chemical Company Immunotechnology Catalog-Protein ...
  http://www.google.com/patents/US7737252?dq=7253017
*  Patent US9272074 - Surgical fasteners and methods for sealing wounds - Google Patents
... wherein upon contact of the reactive members on the surface of the surgical fastener with the complimentary reactive members on ... and providing tissue with a plurality of complementary reactive members of the specific binding pair, ... a wound in tissue is provided which includes providing a surgical fastener having a plurality of reactive members of a specific ... binding pair attached on a surface of the surgical fastener, ... protein inhibitors, protein antagonists, and protein agonists; ...
  http://www.google.ca/patents/US9272074
*  Patent WO1992021770A1 - Reagents and methods for performing two-step ion-capture binding assays - Google Patents
The use of a polycationic substance, having a nitrogen content of at least about two percent (excluding the counter ions), to ... In one embodiment a test sample suspected of containing the analyte of interest may be contacted with the capture reagent to ... The complex is then contacted to the oppositely charged solid phase to attract, attach, and immobilize the capture reagent/ ... and a solid phase material containing a reaction site comprising a polymeric cation substance having a nitrogen content of at ...
  http://www.google.ca/patents/WO1992021770A1?cl=en
*  Application # 2005/0002865. Diagnostic/therapeutic agents - Patents.com
... receptors Biotin biotin transport protein on cell surface Folate folate transport Tumours protein on cell surface Riboflavin ... may be considered as sulfhydryl reagents if linking occurs through the formation of disulphide bridges. Thus reagents which ... brain mitogen specific receptors Apolipoprotein, proteoglycans e.g. specific apolipoprotein B receptors (e.g., LDL receptor) ... 0148] Receptors Comprising Protease Inhibitors 19 Vector type Receptor Comments/areas of use Ref Peptidic or non- Cathepsin B ...
  http://www.patents.com/us-20050002865.html
*  Patent US5182107 - Transferrin receptor specific antibody-neuropharmaceutical or diagnostic ... - Google Patents
Other aspects of this invention include a delivery system comprising an antibody reactive with a transferrin receptor linked to ... of an antibody-neuropharmaceutical or diagnostic agent conjugate wherein the antibody is reactive with a transferrin receptor. ... These receptors are also on the cell surface of the endothelial cells which line brain capillaries. Among the receptor types ... Methods and reagents for activating heat shock protein 70. US20070269427 *. Feb 2, 2004. Nov 22, 2007. Irving Elaine A. ...
  http://www.google.com/patents/US5182107?dq=5,381,459
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
The HIV-1 gp120 protein, a glycoprotein envelope on the surface of HIV-1, plays an important role in viral entry into CD4 cells ... In order to actively target pancreatic cancer cell line, EGFR specific peptide was conjugated on the particle surface through a ... There is an active interest in peptides that readily cross cell membranes without the assistance of cell membrane receptors1. ... By thiolation of gelatin, the sulfhydryl groups could be introduced into the polymer and would form disulfide bond within ...
  https://www.jove.com/visualize/abstract/21998722/direct-translocation-as-major-cellular-uptake-for-cady-self
*  US5434052A - Complementation assay for drug screening - Google Patents
Compounds are evaluated for their binding to naturally occurring receptors, by employing the natural ligand conjugated to an ... Protease EFC cell surface fusion protein assay US20040146956A1 (en) * 2003-01-28. 2004-07-29. Pyare Khanna. Protease efc cell ... The following reagents are prepared:. Binding Protein Receptor Reagent consists of Porcine Intrinsic Factor (0.5 mg/ml, Scripps ... Specific binding assay with an enzyme modulator as a labeling substance EP0042673A1 (en) * 1980-06-20. 1981-12-30. The Regents ...
  https://patents.google.com/patent/US5434052?oq=flatulence
*  Patent US5095030 - Wavelength-specific cytotoxic agents - Google Patents
... to ligands specific for receptor or to specific immunoglobulins or fragments thereof to target specific tissues or cells for ... cells and tissues generally to destroy unwanted targets. The use of the Gp of the invention permits the irradiation to use ... The ligand specific for receptor, Re*, refers to a moiety which binds a receptor at cell surfaces, and thus contains contours ... but a substance complementary to it. It is well understood that a wide variety of cell types have specific receptors designed ...
  http://www.google.com/patents/US5095030?dq=6650327
*  Application # 2016/0194410. BINDING AGENT - Patents.com
0314] Biotinylated ss-L-DNA linkers were captured on the SA surface in the respective flow cells. Flow cell 1 was saturated ... present in a protein. For example, a specific cystein within a rare sequence context can be enzymatically converted in an ... dimer receptor complexes and thus blocking the downstream signal cascade that ultimately results in cell growth and division ( ... An "isolated" binding agent is one which has been identified and separated and/or recovered from e.g. the reagent mixture used ...
  http://patents.com/us-20160194410.html
*  Molecules | Free Full-Text | Radiolabeling Strategies for Tumor-Targeting Proteinaceous Drugs | HTML
As a consequence these drugs allow developing patient-specific therapies that provide the means to go beyond the possibilities ... is a specific HER2 targeting mAb which up-regulates the p27Kip1 protein, resulting in the inhibition of CDK2 and halting cell ... new reagents for radiometal chelate conjugation to antibody sulfhydryl groups undergo pH-dependent cleavage reactions. ... In tumor cells it is common for a particular receptor to be overexpressed and in abundance. For molecular imaging this ...
  http://www.mdpi.com/1420-3049/19/2/2135/htm
*  Book Photoshop Cs2 All In One Desk Reference For Dummies
2002 March-April; specific): 91. , 0 Comments/Trackbacks rates are therapeutic for the book Photoshop of protein, levels, and ... marked failure of various other patients and cell of sub-cellular diseases for receptor. subgroup in endoneurium acid rules in ... book Photoshop CS2 All in One Desk Reference of the sets associated with CHF will result within 5 inhibitors of their surface. ... 0 Comments/Trackbacks book Photoshop CS2 All in: This failure for peritoneum substance cells is all quantitative pathways of ...
  http://sonicboomsound.com/family/March2001/movie/pdf/book-Photoshop-CS2-All-in-One-Desk-Reference-For-Dummies/
*  Plus it
Schneewind O, Mihaylova-Petkov D, and Model P (1993) Cell wall sorting signals in surface protein of Gram-positive bacteria. ... These results suggest that it may be possible to identify inhibitors that discriminate between specific members of the sortase ... These findings not only implicated sulfhydryl (cysteine) as a catalyst for surface protein anchoring but also demonstrated that ... or function as receptors for phage binding. Class B enzymes, SrtB, anchor proteins to the cell wall envelope that are ...
  http://pharmrev.aspetjournals.org/content/60/1/128
*  Patent US6630358 - Arrays of proteins and methods of use thereof - Google Patents
... are immobilized on one or more organic thinfilms on the substrate surface. The protein arrays are particularly useful in drug ... Methods of using the protein arrays are also disclosed. On the arrays, a plurality of different proteins, such as different ... Protein arrays for the parallel, in vitro screening of biomolecular activity are provided. ... and a mixture of protease inhibitors. Cells are transferred to a microcentrifuge tube, allowed to swell for 5 minutes, and ...
  http://www.google.com/patents/US6630358?dq=5,912,661
*  Patent US7011940 - Quality control for cytochemical assays - Google Patents
The invention describes quality control devices for assays that measure analytes in cells and tissue samples, and methods of ... the reagent surface that is devoid of bound peptide, and (2) the test area with specific peptide. The test strip containing no ... Progesterone receptor. p53 protein. Ki-67 protein. Proliferating cell nuclear antigen (PCNA). ... Immunologically active substance-glass conjugates, process for producing the same and diagnostic reagents containing the same. ...
  http://www.google.com/patents/US7011940?dq=6317900
*  US Patent # 7,098,196. Regulators of the hedgehog pathway, compositions and uses related thereto - Patents.com
... methods and reagents for modulating smoothened-dependent pathway activation. In certain embodiments, the subject methods can be ... or it may be compared with the amount of transcription in a substantially identical cell that lacks the target receptor protein ... 1995) Cell 81:445 455). Interestingly, cell surface retention of the N-terminal peptide is dependent on autocleavage, as a ... under specific conditions, can produce daughter cells which terminally differentiate such as into neurons and glia. These cells ...
  http://patents.com/us-7098196.html
*  Patente US5811449 - Treatment for atherosclerosis and other cardiovascular and inflammatory diseases - Google Patentes
... or interferes with a complex formed between the oxidized signal and a protein or peptide that mediates the expression of the ... that includes administering an effective amount of a substance that prevents the oxidation of the oxidized signal, and ... interferes with a complex formed between a polyunsaturated fatty acid or an oxidized polyunsaturated fatty acid and a protein ... Cell surface expression was determined by primary binding with VCAM-1 specific (4B9) and ICAM-1 specific (84H10) mouse ...
  http://www.google.es/patents/US5811449?dq=flatulence
*  Patent US5135863 - Compositions and methods for determining the presence of amphetamines in a ... - Google Patents
Member of a specific binding pair ("sbp member")--one or two different molecules, having an area on the surface or in a cavity ... The chemical reagents can include substrates, coenzymes, enhancers, second enzymes, activators, cofactors, inhibitors, ... The members of the specific binding pair are referred to as ligand and receptor. These will usually be members of an ... The cell suspension was spun down at 800 rpm for 8 minutes and the supernatant poured off. The cells were resuspended in 2 ml/ ...
  http://www.google.com/patents/US5135863?dq=ininventor:oliver+ininventor:steele
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
Cellular Biology, Issue 34, Protein transduction, Cell penetrating peptide, Site-specific recombination, Stem cells, Protein ... In order to actively target pancreatic cancer cell line, EGFR specific peptide was conjugated on the particle surface through a ... Moreover, explants culture can be manipulated by addition of inhibitors, blocking antibodies, growth factors, or even cells or ... It effectively transduces naive mouse T cells if they express a transgenic Coxsackie adenovirus receptor (CAR). Importantly, ...
  https://www.jove.com/visualize/abstract/21698151/the-loss-p53-activator-hipk2-is-responsible-for-galectin-3
*  Protocols and Video Articles Authored by Daniel D. Von Hoff (Translated to Spanish)
We use cell line-specific models to rank the relative importance of protein-protein interactions in the epidermal growth factor ... 2013 , Pubmed ID: 24204627 New anticancer agents that target a single cell surface receptor, up-regulated or amplified gene ... Quiescin Sulfhydryl Oxidase 1 Promotes Invasion of Pancreatic Tumor Cells Mediated by Matrix Metalloproteinases Molecular ... These agents range from a gene-therapy approach to radiation enhancement to inhibitors of protein with increased expression in ...
  https://www.jove.com/author/Daniel++D._Von+Hoff?language=Spanish
*  Patente US8102176 - NMR device for detection of analytes - Google Patentes
... a viral protein (e.g., hemagglutinin), an extracellular matrix protein, a lectin, or an ectodomain of a cell surface protein. ... Hepatocyte-specific receptor-mediated endocytosis-type compositions. US5705628. 20 Sep 1994. 6 Ene 1998. Whitehead Institute ... mast cell inhibitors, adrenergic agonists, beta-blockers, carbonic anhydrase inhibitors/hyperosmotiics, cholinergics, miotics, ... substance abuse agents, deterrent substance abuse agents, and withdrawal substance abuse agents; minerals; and vitamins, such ...
  http://www.google.es/patents/US8102176
*  glutaminase: Topics by WorldWideScience.org
We identified brain-specific angiogenesis inhibitor 2 (BAI2), a member of the adhesion-G protein-coupled receptors (GPCRs), as ... Fas Cell surface death receptor; FDXR: Ferredoxin Reductase; FOXO3a: forkhead box O3; Gadd45a: growth arrest and DNA damage- ... Beef pancreatic asparagine synthetase was inactivated by treatment with the sulfhydryl reagent 5,5'-dithiobis(2-nitro ... The substance that is responsible for a sense of relaxation is theanine. Theanine (γ-glutamylethylamide is a unique non-protein ...
  https://worldwidescience.org/topicpages/g/glutaminase.html