*  Publications [#243615] of Anita T. Layton
To accomplish that goal, we developed a detailed mathematical model of solute transport in the renal medulla of the rat kidney ... The model represents the radial organization of the renal tubules and vessels, which centers around the vascular bundles in the ... on sodium transport, osmolality, and medullary oxygenation cannot be gleaned by considering each solute's effect in isolation. ... Fry, BC; Edwards, A; Layton, AT, Impacts of nitric oxide and superoxide on renal medullary oxygen transport and urine ...
  https://fds.duke.edu/db/aas/math/alayton/publications/243615
*  Functional MRI of the kidney: tools for translational studies of pathophysiology of renal disease
... the anatomic arrangement of the tubules and the vasa recta within the medulla leads to diffusion of oxygen from the arterial to ... Oxygen is one of the key nutrients transported by blood to the tissue, and in most tissues regional PO2 closely follows the ... most of it is directed toward the cortex to optimize glomerular filtration and reabsorption of solute. By contrast, blood flow ... Maril N, Margalit R, Mispelter J, Degani H. Functional sodium magnetic resonance imaging of the intact rat kidney. Kidney Int. ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2919069/
*  MCAT - Biology Flashcards by Caitlin Rodeghier | Brainscape
... and other solutes takes place via secondary active transport proteins on the apical membrane of the tubules.. -> once these ... Dips into medulla. Function is to increase solute conc, and thus osmotic pressure, of medulla.. -> as filtrate descends into ... Causes the collecting ducts of the kidney to become permeable to water concentrating/reducing the amount of urine. Also ... transport proteins are completely saturated with a solute, any additional solute is washed into the urine.. Some solutes not ...
  https://www.brainscape.com/flashcards/mcat-biology-422004/packs/486133
*  Harold Layton, Professor
Ion TransportKidneyKidney Concentrating Ability • Kidney Diseases • Kidney Glomerulus • Kidney MedullaKidney Tubules ... Modeling Solute Transport and Urine Concentrating Mechanism in the Rat Kidney, National Institutes of Health, 2010/08-2016/07. ... Kidney Tubules, Collecting • Loop of Henle • Mathematics • Membrane Potentials • Mice • Models, Animal • Models, Biological • ... Countercurrent multiplication may not explain the axial osmolality gradient in the outer medulla of the rat kidney., American ...
  http://fds.duke.edu/db?dir-39-122-1761
*  Tubular Transport of NaCl and Water Flashcards by Jeffrey Lee | Brainscape
Study Tubular Transport of NaCl and Water flashcards from Jeffrey Lee ... Solutes and water are reabsorbed from the lumen (urinary space) back into the medulla. How does the water and solutes make it ... As solutes and water flow through tubules, they pass different reabsorptive mechanisms. If the flow is faster, there is less ... The _____ _____ establishes the osmotic gradient from the cortex to the medulla of the kidney and the _____ _____maintains the ...
  https://www.brainscape.com/flashcards/tubular-transport-of-nacl-and-water-5143061/packs/7604581
*  Processes involved in the human kidney Essay Example for Free
Very selective process with both passive and active transport of solutes. -Proximal, distal tubules, and loop of Henle ... Kidney consists of outer renal cortex and inner renal medulla. -Nephron is functional unit of vertebrate kidney ... Processes involved in the human kidney -Blood enters each kidney via renal artery and leaves each kidney via renal vein ... Processes involved in the human kidney Essay. Custom Student Mr. Teacher ENG 1001-04 20 July 2016 ...
  https://studymoose.com/processes-involved-in-the-human-kidney-essay
*  Urea and urine concentrating ability: new insights from studies in mice | Renal Physiology
This spatial dissociation of water and urea transport favors a more efficient accumulation of solutes in the inner medulla in ... BrayGA and Scott-Preston A. The role of urea in the concentration of non-urea solutes by the kidney. In: Urea and the Kidney, ... ForsterRP. Active cellular transport of urea by frog renal tubules. Am J Physiol179 : 372-377, 1954. ... KnepperMA and Roch-Ramel F. Pathways of urea transport in the mammalian kidney. Kidney Int31 : 629-633, 1987. ...
  http://ajprenal.physiology.org/content/288/5/F881.full
*  The Endurolytes Rationale | Hammer Nutrition
A NUMBER OF FACTORS CONTRIBUTE TO THE FORMATION OF THE MEDULLARY SOLUTE GRADIENT AND INCLUDE:. 1) Sodium and chloride transport ... They key to urine concentration is a solute gradient that is established in the tissues of the renal medulla. If we were to ... Polyuria (if normal kidney function) -Kidney Stones -Blood clots -Check for Homan's Sign -Arrhythmias -EKG changes ... of aldosterone by the adrenal cortex culminating in an action of this mineralocorticoid on the renal tubules to increase sodium ...
  http://www.hammernutrition.com/knowledge/advanced-knowledge/the-endurolytes-rationale/
*  Frontiers | Urea Transporter Physiology Studied in Knockout Mice | Physiology
In the kidney, deletion of UTA1/A3 results in polyuria and a severe urine concentrating defect, indicating that intrarenal ... In the kidney, deletion of UTA1/A3 results in polyuria and a severe urine concentrating defect, indicating that intrarenal ... while UT-B demonstrates a broader distribution in kidney, heart, brain, testis, urinary tract and other tissues. Over the past ... while UT-B demonstrates a broader distribution in kidney, heart, brain, testis, urinary tract and other tissues. Over the past ...
  https://www.frontiersin.org/articles/10.3389/fphys.2012.00217/full
*  Osmoregulation - Wikipedia
... in the medulla portion of the kidney. reabsorption - most of the viscous glomerular filtrate is returned to blood vessels that ... Sharks, having slightly higher solute concentration (i.e., above 1000 mOsm which is sea solute concentration), do not drink ... very large role in human osmoregulation by regulating the amount of water reabsorbed from glomerular filtrate in kidney tubules ... from the intracellular fluid by diffusion and active transport. As osmotic action pushes water from the environment into the ...
  https://en.wikipedia.org/wiki/Osmoregulation
*  Anita T. Layton, Robert R. & Katherine B. Penn Professor of Mathematics and Professor of Biomedical Engineering
Ion TransportKidneyKidney Concentrating Ability • Kidney Diseases • Kidney Glomerulus • Kidney MedullaKidney Tubules ... Modeling Solute Transport and Urine Concentrating Mechanism in the Rat Kidney, National Institutes of Health, 2010/08-2016/07. ... Kidney Tubules, Collecting • Kidney Tubules, Proximal • Kinetics • Loop of Henle • Male • Mathematics • Membrane Potentials • ... Modeling Solute Transport and Urine Concentrating Mechanism in the Rat Kidney, National Institutes of Health, 2010/08-2015/07. ...
  https://fds.duke.edu/db/aas/math/faculty/alayton
*  Free Medical Flashcards about A&P Ch 15 Urinary Sy
lies deep in the kidney & consists of many triangular regions with a striped appearance. renal medulla. ... types & amounts of solutes in the body. deficit of sodium ions in ECF results in. water loss from bloodstream into tissue ... active transport in ascending limb of the Loop of Henle _____ concentration of interstitium. increases. ... renal tubules to excrete basic/acid ions to maintain blood pH homeostasis. ...
  https://www.studystack.com/flashcard-311207
*  Essay on The Kidneys - 2927 Words
Very selective process with both passive and active transport of solutes -Proximal, distal tubules, and loop of Henle ... Kidney consists of outer renal cortex and inner renal medulla -Nephron is functional unit of vertebrate kidney -Consists of ... Kidney Essay ...The kidney as several roles as a homeostatic organ, one of the roles is the regulation of blood PH 'the kidney ... Blood enters each kidney via renal artery and leaves each kidney via renal vein -Urine exists the kidney through a duct called ...
  http://www.studymode.com/essays/The-Kidneys-1453776.html
*  PSL301: Water 3 Flashcards by Airi - | Brainscape
Polarized, so have different transport proteins on each side. Solutes must pass through different ones to get to other side. ... What signals do the tubules receive, and what do they do? - hormones. - nerves. - pH. - electrolyte concentrations. - pressure ... transport 2 things in the same direction. - movement of 1 thing down the gradient drives movement of other against the gradient ... transport 2 things in opposite directions. - movement of 1 thing down the gradient drives movement of other against the ...
  https://www.brainscape.com/flashcards/psl301-water-3-2120349/packs/3327077
*  Water Handling Flashcards by Carl Dernell | Brainscape
Assume 600 mOsm is the average daily solute load and your given Kidney's max is 300mOsm/kg water. • 600mOsm/300mOsm/kg water = ... Derives energy from active transport of Cl in the water impermeable thick ascending limb. ○ Na/K/2Cl cotransporter. • This ... Thus, cortex is least hypertonic, medulla is more, and the papilla is the most hypertonic. • Thus, vasopressin making ... Block ADH action on tubules. • Increase dilation of efferent and afferent arteriole (increases GFR, which increases flow rate ...
  https://www.brainscape.com/flashcards/water-handling-5156475/packs/7588852
*  CHAPTER 44
2. This active transport and other active transport systems in the kidney consume considerable ATP, requiring the kidney to ... These contain cilia that draw water and solutes from the interstitial fluid into the tubule system. The urine in the tubules ... J. Before leaving the kidney, the urine may obtain the osmolarity of the interstitial fluid in the inner medulla, which can be ... C. The mammalian kidney has two distinct regions, an outer renal cortex and an inner renal medulla. ...
  http://thelessonlocker.com/kvhs/biology/Osmoregulation_Excretion_Notes.html
*  Topic 11.3: The Kidney and Osmoregulation - AMAZING WORLD OF SCIENCE WITH MR. GREEN
The role of the loop of Henle is to create a solute concentration gradient in the medulla of the kidney.*The descending loop of ... Cells lining the tubules actively transport ions and uric acid from the hemolymph into the lumen of the tubules. This draws ... Kidney Transplant*A better long term treatment for a kidney that is not working properly is a kidney transplant ... co-transported out of filtrate and into fluid outside the tubule, by co-transporter proteins in outer membranes of tubules ...
  https://www.mrgscience.com/topic-113-the-kidney-and-osmoregulation.html
*  Nephron - Wikipedia
... allowing some of it to enter the medulla of the kidney, thus maintaining its high concentration (which is very important for ... The glomerular blood pressure provides the driving force for water and solutes to be filtered out of the blood plasma, and into ... Much of the ion transport taking place in the distal convoluted tubule is regulated by the endocrine system. In the presence of ... Reabsorption occurs in the renal tubules and is either passive, due to diffusion, or active, due to pumping against a ...
  https://en.wikipedia.org/wiki/Nephron
*  Carl W. Gottschalk | Biographical Memoirs: V.77 | The National Academies Press
A micropuncture study of the pressures in the proximal tubules and peritubular capillaries of the rat kidney and their relation ... diffusion of water out of the collecting ducts into the fluid surrounding them in the renal medulla and involved salt transport ... Also, by micropuncture they found that during hydropenia the concentration of solutes in distal tubular fluid at the surface of ... It had been known for many years that denervation of a kidney increases the rate of salt and water excretion by that kidney. ...
  https://www.nap.edu/read/9681/chapter/10
*  PPT - The Urinary System PowerPoint Presentation - ID:782228
Two distinct regions are found within the kidney: a renal medulla and a renal cortex. ... Active transport mechanisms move excess hydrogen ions into the renal tubule along with various organic compounds. ... Urine composition varies from time to time and reflects the amounts of water and solutes that the kidneys eliminate to maintain ... Kidney Structure*A medial depression in the kidney leads to a hollow renal sinus into which blood vessels, nerves, lymphatic ...
  https://www.slideserve.com/kostya/the-urinary-system
*  PPT - Urinary System PowerPoint Presentation - ID:2241524
Some urea also diffuses out of the duct to contribute to the high solute concentration of the inner medulla ... introduction and organization kidney structure and blood supply renal physiology urine transport, storage, and ... proximal and distal convoluted tubules, reabsorption of water, renal artery, renal cortex, renal medulla, renal pelvis, renal ... Most ions (Na+) actively transported back into blood, which causes transport of negative ions (Cl- ) by diffusion and water by ...
  https://www.slideserve.com/cynara/urinary-system
*  Chapter 27: Urinary System Flashcards - ANATOMY LECTURE | Brainscape
which type of nephron has only a small amount of its structure in the kidney medulla ... Which urinary organ is responsible for transporting urine from kidney to urinary bladder via peristalsis ... Extensions of the renal cortex is called ________ _______, which project into the renal medulla and subdivide the medulla into ... Which component of the urinary tract originates at the renal pelvis as it exits the hilum of the kidney then enters the ...
  https://www.brainscape.com/flashcards/chapter-27-urinary-system-5346855/packs/7916426
*  Free Medical Flashcards about Chapter 15 DRW
medulla. inner region of kidney. renal pyramids. triangular tissues in renal medulla contain loops and collecting tubules of ... fluid released by kidneys transported by ureters retained in bladder and eliminated through urethra consists of water and other ... solute. substance disolved in solution. specific gravity. weight of substance compared with equal volume of water. ... kidney transplantation. surgical implantation of a healthy human donor kidney into body of patient with irreversible kidney ...
  https://www.studystack.com/flashcard-568017
*  Countercurrent multiplication - Wikipedia
... but permeable to solutes, but here Na+, Cl−, and K+ are actively transported into the medullary space, making the filtrate ... The term derives from the form and function of the loop of Henle, which consists of two parallel limbs of renal tubules running ... the production of hyperosmotic urine by the mammalian kidney. The ability to concentrate urine is also present in birds. ... the vasa recta's counter current exchange to prevent the wash out of salts and maintain a high osmolarity at the inner medulla ...
  https://en.wikipedia.org/wiki/Countercurrent_multiplication
*  A gene expression resource generated by genome-wide lacZ profiling in the mouse | Disease Models & Mechanisms
For example, consistent with previous data indicating a role in the proximal convoluted tubules of the kidney (Vallon et al., ... SLC5A2 encodes the sodium-dependent glucose transport protein solute carrier family 5, member 2, dysfunction of which is ... L,M) Vascular staining on blood vessels (red arrow). (N) Heart and aorta (arrow). (O) Adrenal medulla. (P) Pancreas. (Q) Skin ... 2011) localised Slc5a2 expression to the brush border membrane of proximal convoluted tubules, located in the kidney cortex. We ...
  http://dmm.biologists.org/content/8/11/1467