*  British Library EThOS: Pharmacological studies of voltage-gated sodium channel expression in human breast cancer cells :...
The specific aims were threefold, as follows: 1) To test the effects of several types of voltage-gated sodium channel (VGSC) ... Pharmacological studies of voltage-gated sodium channel expression in human breast cancer cells : control of metastatic cell ...
  http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.539266
*  PLOS Computational Biology: Impact of Fast Sodium Channel Inactivation on Spike Threshold Dynamics and Synaptic Integration
Spikes are generated by sodium channels, which inactivate when the neuron is depolarized, raising the threshold for spike ... We found that inactivation properties of sodium channels could indeed cause substantial threshold variability in central ...
  http://journals.plos.org/ploscompbiol/article/comments?id=10.1371/journal.pcbi.1001129&imageURI=info:doi/10.1371/journal.pcbi.1001129.g007
*  Rare Genetic Disorder: Sodium channels
Sodium channels. Voltage-gated sodium channels play a critical role in the generation and conduction of action potentials - so ... that can modulate the kinetics and voltage dependence of channel gating. Till 2007, 9 isoforms of the sodium-channel α subunit ... 4 closely related sodium channels (Nav 1.1, -1.2, -1.3, and -1.7) are encoded by a set of 4 genes (SCN1A, SCN2A, SCN3A, and ... Sodium channels are integral membrane proteins and are comprised of a large α subunit, which forms the voltage-sensitive and ...
  http://raregeneticdisorder.blogspot.com/2012/08/sodium-channels.html
*  Omega Research
... tested their effects on the electrophysiology of rat hippocampal CA1 neurons and found that the sodium and calcium ion channels ... the ion channels penetrate the membrane bilayer in juxtaposition with the ion channels rather than directly on the channel ... The PUFAs act by stabilizing electrically every cardiac myocyte by modulating conductance of ion channels in the sarcolemma, ... These PUFAs then allosterically alter the conformation and conductance of the channels. Both potential benefits and possible ...
  http://omega-research.com/researchview.php?ID=2988&catid=8
*  Anti-epithelial Sodium Channel gamma抗体(ab3468)参考文献
引用Abcam's Anti-epithelial Sodium Channel gamma抗体(ab3468)的参考文献列表。为您列举引用本产 ... Sun X et al. Regulation of miR-101/miR-199a-3p by the epithelial sodium channel during embryo implantation: involvement of CREB ... Zhao R et al. Correlation of apical fluid-regulating channel proteins with lung function in human COPD lungs. PLoS One 9: ... Ohsawa M et al. Deletion of the angiotensin II type 1 receptor-associated protein enhances renal sodium reabsorption and
  http://www.abcam.cn/epithelial-sodium-channel-gamma-antibody-ab3468-references.html
*  Channelpedia
Structure and distribution of a broadly expressed atypical sodium channel. FEBS Lett., 1997 Jan 3 , 400 (183-7).. ... Assignment of a human voltage-dependent sodium channel alpha-subunit gene (SCN6A) to 2q21-q23. Genomics, 1994 Jan 15 , 19 (395- ... 1, but there are fewer basic residues in repeat domains 1, 3, and 4 than in other cloned sodium channels. [873] ... Molecular cloning of an atypical voltage-gated sodium channel expressed in human heart and uterus: evidence for a distinct gene ...
  http://channelpedia.epfl.ch/ionchannels/129
*  Epicardial Border Zone Overexpression of Skeletal Muscle Sodium Channel SkM1 Normalizes Activation, Preserves Conduction, and...
Epicardial Border Zone Overexpression of Skeletal Muscle Sodium Channel SkM1 Normalizes Activation, Preserves Conduction, and ... Epicardial Border Zone Overexpression of Skeletal Muscle Sodium Channel SkM1 Normalizes Activation, Preserves Conduction, and ... Epicardial Border Zone Overexpression of Skeletal Muscle Sodium Channel SkM1 Normalizes Activation, Preserves Conduction, and ... Epicardial Border Zone Overexpression of Skeletal Muscle Sodium Channel SkM1 Normalizes Activation, Preserves Conduction, and ...
  http://circ.ahajournals.org/content/early/2008/12/22/CIRCULATIONAHA.108.809301
*  "The Relationship Between Voltage-Gated Sodium Channel Inactivation Fir" by J. F. Atherton, A. J. Gillies et al.
The Relationship Between Voltage-Gated Sodium Channel Inactivation Firing Frequency in the Subthalamic Nucleus Projection ... The Relationship Between Voltage-Gated Sodium Channel Inactivation Firing Frequency in the Subthalamic Nucleus Projection ...
  https://corescholar.libraries.wright.edu/ncbp/637/
*  Sodium channels in cardiac Purkinje cells | SpringerLink
Sodium (Na+) currents are responsible for excitation and conduction in most cardiac cells, but their study has been hampered by ... Bean, B. P., Cohen, C. J., and Tsien, R. W., Block of cardiac sodium channels by tetrodotoxin and lidocaine: Sodium currents ... Aldrich, R. W., Corey, D. P., and Stevens, C. F., A reinterpretation of mammalian sodium channel gating based on single channel ... Colatsky, T. J., and Tsien, R. W., Sodium channels in rabbit cardiac Purkinje fibres. Nature278 (1979) 265-268.PubMedGoogle ...
  https://link.springer.com/article/10.1007/BF01945516
*  Species: Epithelial sodium channel (IPR001873) | InterPro | EMBL-EBI
Species: Epithelial sodium channel (IPR001873). Key Species. Key species. Number of proteins. FASTA. Protein IDs. ...
  http://www.ebi.ac.uk/interpro/entry/IPR001873/taxonomy
*  Voltage-Gated Sodium Channels
Noteflight is an online music writing application that lets you create, view, print and hear professional quality music notation right in your web browser.
  https://www.noteflight.com/scores/view/86502e9f2f0261a1da1ef92f2c0b8a9cefd2988a
*  Voltage gated sodium channel, alpha-11 subunit (IPR028821) | InterPro | EMBL-EBI
Nav1.9 (sodium channel protein type 11 subunit alpha) is a tetrodotoxin-resistant sodium channel isoform [PMID: 10580103, PMID ... Voltage gated sodium channel, alpha subunit (IPR001696) *Voltage gated sodium channel, alpha-11 subunit (IPR028821) ... Nine voltage-gated sodium channels (Navs) are expressed in complex patterns in mammalian nerve and muscle. These channels ... Voltage gated sodium channel, alpha-11 subunit (IPR028821). Short name: Na_channel_a11su ...
  http://www.ebi.ac.uk/interpro/entry/IPR028821
*  Frontiers | Propranolol Blocks Cardiac and Neuronal Voltage-Gated Sodium Channels | Pharmacology
Heterologous Expression of Sodium Channels. A recombinant human NaV1.5 sodium channel cDNA in a mammalian expression plasmid ( ... We established that cardiac sodium channels have greater affinity for propranolol than brain sodium channels, that block is not ... These data indicate that brain sodium channels exhibit less sensitivity to R-(+)-propranolol than NaV1.5 channels. Based upon ... Finally, we observed that brain sodium channels exhibited less sensitivity to R-(+)-propranolol than NaV1.5 channels. Our ...
  https://www.frontiersin.org/articles/10.3389/fphar.2010.00144/full
*  Voltage Gated Sodium Channels | Springer for Research & Development
Ion channel biophysicists have at their disposal a rich and ever-growi ... A number of techniques to study ion channels have been developed since the electrical basis of excitability was first ... These structures, along with those from other channels, give unprecedented insight into the structural basis of sodium channel ... Altered Sodium Channel Gating as Molecular Basis for Pain: Contribution of Activation, Inactivation, and Resurgent Currents ...
  https://rd.springer.com/book/10.1007/978-3-642-41588-3
*  Sodium channels amplify spine potentials - Academic Commons
We tested this by measuring the effect of the sodium channel blocker tetrodotoxin (TTX) on depolarizations generated by two- ... Spine sodium channels could boost synaptic potentials and facilitate action potential backpropagation. ... Past theoretical work and recent experimental evidence have suggested that spines could contain sodium channels. ... from neocortical pyramidal neurons are electrically isolated from the dendrite and indicate that they have sodium channels and ...
  https://academiccommons.columbia.edu/catalog/ac%3A150362
*  Marine Drugs | Free Full-Text | Shellfish Toxins Targeting Voltage-Gated Sodium Channels | Notes
Voltage-gated sodium channels (VGSCs) play a central role in the generation and propagation of action potentials in excitable ...
  http://www.mdpi.com/1660-3397/11/12/4698/notes
*  Frontiers | Regulation of Lung Epithelial Sodium Channels by Cytokines and Chemokines | Immunology
Reabsorption is a two-step process: first, sodium enters via sodium-permeable channels in the apical membranes of alveolar type ... Cytokines and chemokines affect alveolar amiloride-sensitive epithelial sodium channels (ENaC) which play a crucial role in ... via sodium-permeable channels in the apical membranes of alveolar type 1 and 2 cells followed by active extrusion of sodium ... inflammation can have a particularly profound effect on lung sodium transport since they can alter both ion channel and barrier ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2017.00766/full
*  New Insights into the Epithelial Sodium Channel Using Directed Mutagenesis | IntechOpen
New Insights into the Epithelial Sodium Channel Using Directed Mutagenesis , IntechOpen, Published on: 2013-02-05. Authors: ... 32 - S Kellenberger, L Schild, 2002Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a ... 26 - J. D Horisberger, A Chraibi, 2004Epithelial Sodium Channel: A Ligand-Gated Channel? Nephron Physiology 963741 ... 1999Epithelial sodium channel in human epidermal keratinocytes: expression of its subunits and relation to sodium transport and ...
  https://www.intechopen.com/books/genetic-manipulation-of-dna-and-protein-examples-from-current-research/new-insights-into-the-epithelial-sodium-channel-using-directed-mutagenesis/
*  Traumatic Axonal Injury Induces Calcium Influx Modulated by Tetrodotoxin-Sensitive Sodium Channels | Journal of Neuroscience
Traumatic Axonal Injury Induces Calcium Influx Modulated by Tetrodotoxin-Sensitive Sodium Channels. John A. Wolf, Peter K. Stys ... 1, Strain on the axonal membrane inducing an abnormal influx of Na+ through mechanosensitive sodium channels. 2, In response, ... 1999) Membrane stretch affects gating modes of a skeletal muscle sodium channel. Biophys J 77:758-774. ... 1999) Voltage-dependent sodium channel function is regulated through membrane mechanics. Biophys J 77:1945-1959. ...
  http://www.jneurosci.org/content/21/6/1923
*  The Genetic Architecture of Degenerin/Epithelial Sodium Channels in Drosophila
Evolution of the epithelial sodium channel and the sodium pump as limiting factors of aldosterone action on sodium transport. ... Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure. Physiol. Rev. 82: ... The Genetic Architecture of Degenerin/Epithelial Sodium Channels in Drosophila. Kathleen M. Zelle,1 Beika Lu,1,2 Sarah C. ... Sensory functions for degenerin/epithelial sodium channels (DEG/ENaC). Adv. Genet. 76: 1-26 [PMC free article] [PubMed] ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC3583452/?lang=en-ca
*  Stereoselective Block of Cardiac Sodium Channels by Bupivacaine in Guinea Pig Ventricular Myocytes | Circulation
To estimate the apparent rate constants for the drug-channel interactions, we used a state diagram for the sodium channel ... Stereoselective Block of Cardiac Sodium Channels by Bupivacaine in Guinea Pig Ventricular Myocytes. Carmen Valenzuela, Dirk J. ... If the R(+)-enantiomer is more potent in blocking cardiac sodium channels, then the S(−)-enantiomer could be used with less ... Clarkson C, Follmer C, Ten Eick R, Hondeghem L, Yeh J. Evidence for two components of sodium channel block by lidocaine in ...
  http://circ.ahajournals.org/content/92/10/3014
*  Efficacy Study of Sodium Channel Blocker in LQT3 Patients - Full Text View - ClinicalTrials.gov
Efficacy Study of Sodium Channel Blocker in LQT3 Patients. This study is currently recruiting participants. See Contacts and ... The purpose of this study is to determine whether late sodium channel blockade might be effective in shortening the QTc ... In vitro studies of specific mutation show no effect of ranolazine on late sodium current kinetics or show repolarization ... Ranolazine shortens repolarization in patients with sustained inward sodium current due to type-3 long-QT syndrome. J ...
  https://clinicaltrials.gov/ct2/show/NCT01648205?cond=%22Andersen-Tawil+syndrome%22+OR+%22Long+QT+Syndrome%22&rank=12
*  Altered sodium channel-protein associations in critical illness myopathy
... in sodium channel gating must be due to post-translational modification of sodium channels or an alteration in sodium channel ... Keywords: Skeletal muscle, NaV 1.4 sodium channel, NaV 1.5 sodium channel, Nitric oxide (NO), Neuronal nitric oxide synthase ( ... A major contributor to this sodium channel inactivation is a hyperpolarized shift in the voltage dependence of sodium channel ... Co-immunoprecipitation experiments carried out with a pan-sodium channel antibody confirmed that the sodium channel was ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC3441911/?lang=en-ca
*  Voltage-Gated Sodium Channel in Grasshopper Mice Defends Against Bark Scorpion Toxin | Science
Voltage-Gated Sodium Channel in Grasshopper Mice Defends Against Bark Scorpion Toxin ... Voltage-Gated Sodium Channel in Grasshopper Mice Defends Against Bark Scorpion Toxin ... Voltage-Gated Sodium Channel in Grasshopper Mice Defends Against Bark Scorpion Toxin ... Voltage-Gated Sodium Channel in Grasshopper Mice Defends Against Bark Scorpion Toxin ...
  http://science.sciencemag.org/content/342/6157/441.full
*  Sodium channel blocking agent legal definition of sodium channel blocking agent
What is sodium channel blocking agent? Meaning of sodium channel blocking agent as a legal term. What does sodium channel ... Definition of sodium channel blocking agent in the Legal Dictionary - by Free online English dictionary and encyclopedia. ... Sodium channel blocking agent legal definition of sodium channel blocking agent https://legal-dictionary.thefreedictionary.com/ ... redirected from sodium channel blocking agent). Also found in: Dictionary, Thesaurus, Medical, Financial, Encyclopedia. Agent. ...
  http://legal-dictionary.thefreedictionary.com/sodium+channel+blocking+agent