*  Hereditary leiomyomatosis and renal cell cancer syndrome - Wikipedia
... skin leiomyomata and papillary renal cell cancer". Nature Genetics. 30 (4): 406-410. doi:10.1038/ng849. PMID 11865300. Bayley, ... As the skin lesions are typically painful, it is also often necessary to exclude other painful tumors of the skin (including ... Reed, W. B.; Walker, R.; Horowitz, R. (1973). "Cutaneous leiomyomata with uterine leiomyomata". Acta dermato-venereologica. 53 ... "Combination of pulmonary lymphangioleiomyomatosis with skin leiomyomatosis and uterine leiomyoma". Arkhiv patologii. 63 (6): 39 ...
  https://en.wikipedia.org/wiki/Hereditary_leiomyomatosis_and_renal_cell_cancer_syndrome
*  Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal Cancer - Full Text...
... skin leiomyoma and uterine leiomyoma; multiple skin leiomyomas; kidney cancer and uterine leiomyomas, or kidney cancer ... Some people develop red bumps on their skin that can be painful at times. Some women with HLRCC can develop leiomyomas of the ... Skin biopsy (surgical removal of a small sample of skin tissue). *Cheek swab or mouth rinse to collect cells for genetic ... This includes people in families in which one or more members has skin leiomyoma and kidney cancer; ...
  https://clinicaltrials.gov/ct2/show/NCT00050752?cond=%22hereditary+leiomyomatosis+and+renal+cell+cancer%22&rank=3
*  A Phase II Study of Bevacizumab and Erlotinib in Subjects With Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC)...
Effect on HLRCC associated uterine and skin leiomyomas. [ Time Frame: 4-5 years ]. Correlation between therapy and skin ... Leiomyoma. Neoplasms, Muscle Tissue. Neoplasms, Connective and Soft Tissue. Skin Diseases. Genital Neoplasms, Female. Uterine ... Skin Neoplasms. Uterine Neoplasms. Adenocarcinoma. Carcinoma. Neoplasms, Glandular and Epithelial. Neoplasms by Histologic Type ... Evaluate modulation of HIF, VEGF and EGFR pathways in cutaneous leiomyomas (in patients with HLRCC) and in renal tumors ...
  https://clinicaltrials.gov/ct2/show/NCT01130519
*  Leiomyomatosis | definition of leiomyomatosis by Medical dictionary
Multiple skin leiomyomas may portend symptomatic fibroids. Our case of ganglioneuroma with leiomyomatosis of the urinary ... leio·my·o·ma·to·sis/ (-mi″o-mah-to´sis) the occurrence of multiple leiomyomas throughout the body.. lei·o·my·o·ma·to·sis (lī'ō- ... Related to leiomyomatosis: leiomyomata, leiomyosarcoma, leiomyomatosis peritonealis disseminata lei·o·my·o·ma·to·sis. (lī'ō- ... The state of having multiple leiomyomas throughout the body.. leiomyomatosis. / ...
  https://medical-dictionary.thefreedictionary.com/leiomyomatosis
*  IJMS | Free Full-Text | Protein Profiling of Blood Samples from Patients with Hereditary Leiomyomatosis and Renal Cell Cancer...
HLRCC is characterized by a predisposition to leiomyomas of the skin and the uterus as well as renal cell carcinoma. The ... HLRCC is characterized by a predisposition to leiomyomas of the skin and the uterus as well as renal cell carcinoma. The ... Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer ... dominant tumor susceptibility syndrome characterized by a predisposition for the development of benign leiomyomas of the skin ...
  http://www.mdpi.com/1422-0067/13/11/14518/htm
*  Genetics of Kidney Cancer (Renal Cell Cancer) (PDQ )
... uterine leiomyomas (fibroids), and RCC. Affected individuals may have multiple cutaneous leiomyomas, a single skin leiomyoma, ... Multiple cutaneous leiomyomas with at least one histologically confirmed leiomyoma.. *A single leiomyoma in the presence of a ... Uterine leiomyomas. Uterine leiomyomas are best evaluated by a gynecologist. The uterine leiomyomas of HLRCC are treated in the ... Yosipovitch G, DeVore A, Dawn A: Obesity and the skin: skin physiology and skin manifestations of obesity. J Am Acad Dermatol ...
  https://www.meb.uni-bonn.de/cancer.gov/CDR0000574548.html
*  Plus it
Multiple Leiomyoma Consortium. Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata ... Isolation and Culture of Cybrid Cell Lines and Their Culture. Primary skin fibroblasts were obtained from a 9-month-old male ... Superoxide-induced massive apoptosis in cultured skin fibroblasts harboring the neurogenic ataxia retinitis pigmentosa (NARP) ... Increased Susceptibility to UV-Induced Skin Carcinogenesis in Polymerase η-deficient Mice ...
  http://cancerres.aacrjournals.org/content/65/5/1655
*  Lauri Aaltonen - Helsingin yliopiston tutkimusportaali - Helsingin yliopisto
Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer ... Multiple Leiomyoma Consortium 2002 julkaisussa : Nature Genetics. 30, s. 406-410 5 Sivumäärä. Tutkimustuotos: Artikkelijulkaisu ...
  https://tuhat.helsinki.fi/portal/fi/persons/lauri-aaltonen
*  Imaging of tumor glucose utilization with positron emission tomography | SpringerLink
2002). Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell ...
  https://link.springer.com/article/10.1007%2Fs10555-008-9151-x
*  Pheochromocytomas and Paragangliomas: Genetics and Pathophysiology | Springer for Research & Development
Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer ...
  https://rd.springer.com/chapter/10.1007/978-3-319-62470-9_8
*  Angioleiomyoma - Wikipedia
... of the skin is thought to arise from vascular smooth muscle, and is generally acquired. Leiomyoma Skin lesions Freedberg, et al ...
  https://en.wikipedia.org/wiki/Angioleiomyoma
*  Solitary cutaneous leiomyoma - Wikipedia
... with overlying skin that may have a reddish or violaceous tint. Multiple cutaneous leiomyoma Leiomyoma Skin lesion James, ... Solitary cutaneous leiomyoma typically presents as a deeply circumscribed, freely movable, rounded nodule ranging from 2 to ... William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN ...
  https://en.wikipedia.org/wiki/Solitary_cutaneous_leiomyoma
*  Angiolipoleiomyoma - Wikipedia
Leiomyoma Skin lesion List of cutaneous conditions James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of ... the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.. ...
  https://en.wikipedia.org/wiki/Angiolipoleiomyoma
*  Ocella - FDA prescribing information, side effects and uses
Depression, pulmonary embolism, toxic skin eruption, and uterine leiomyoma.. Postmarketing Experience. The following adverse ... Skin and subcutaneous tissue disorders: Chloasma. Drug Interactions. Consult the labeling of all concurrently-used drugs to ... Birth control pills may not be a good choice for you if you have ever had jaundice (yellowing of the skin or eyes) caused by ... Blotchy darkening of the skin, especially on the face. •. High blood sugar, especially in women who already have diabetes. •. ...
  https://www.drugs.com/pro/ocella.html
*  DailyMed - OCELLA- drospirenone and ethinyl estradiol
Depression, pulmonary embolism, toxic skin eruption, and uterine leiomyoma.. 6.2 Postmarketing Experience. The following ... Blotchy darkening of the skin, especially on the face • High blood sugar, especially in women who already have diabetes • High ... Yellowing of the skin or eyeballs What are the Common Side Effects of Birth Control Pills? ... Birth control pills may not be a good choice for you if you have ever had jaundice (yellowing of the skin or eyes) caused by ...
  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0d729f4d-2fa3-47f6-8a1f-d8cfea4cff37
*  Uterine Fibroids: Pathogenesis and Interactions with Endometrium and Endomyometrial Junction
This syndrome predisposes patients to benign leiomyomas of skin and uterus and early-onset renal cell carcinoma. Fumarate ... They demonstrated that coculture of adipocytes and uterine leiomyoma cells results in an increased proliferation of leiomyoma ... and thus play a crucial role in leiomyoma cell growth, by upregulation of Bcl-2 protein expression in leiomyoma cells [104]. ... have also been implicated in leiomyoma remodeling. Bodner-Adler et al. [128] found that MMP-1 is expressed more in leiomyomas, ...
  https://www.hindawi.com/journals/ogi/2013/173184/
*  IDH1 or -2 mutations do not predict outcome and do not cause loss of 5-hydroxymethylcytosine or altered histone modifications...
Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer ... Cores from skin, colon, tonsil, prostate, breast carcinoma, spleen and liver were included for control and orientation purposes ... Cores from growth plate, articular cartilage, breast carcinoma, prostate, colon, skin and tonsil were included for control and ... in hereditary leiomyomas and renal cell cancer (HLRCC) [33]. Mutations in either SDH or FH lead to loss of function, resulting ...
  https://clinicalsarcomaresearch.biomedcentral.com/articles/10.1186/s13569-017-0074-6
*  Targeting Cancer Metabolism - Revisiting the Warburg Effects
... and Multiple Leiomyoma Consortium (2002). Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin ...
  http://www.toxicolres.org/journal/view.html?uid=372&vmd=Full
*  Leiomyoma - American Osteopathic College of Dermatology (AOCD)
... dartoic/genital leiomyomas) and the arrector pili of the skin (pilar leiomyomas). Arrector pili are small muscles attached to ... In the skin, leiomyomas are categorized based on 3 sites of origin: blood vessel walls (angioleiomyomas), muscles of the ... Pilar leiomyomas are the most common of the cutaneous types and the lesions are often multiple and painful. A burning or sharp ... Leiomyoma describes a benign growth of smooth muscle tissue. These tumors can occur anywhere in the body where smooth muscle is ...
  http://www.aocd.org/?page=Leiomyoma
*  Bilateral Nipple Leiomyoma
H. W. Kloepfer, J. Krafchuk, V. Derbes, and J. Burks, "Hereditary multiple leiomyoma of the skin," American Journal of Human ... genital leiomyoma (solitary), and leiomyomas with additional mesenchymal elements [1]. Leiomyomas have been reported ... Cutaneous leiomyomas are benign smooth muscle neoplasms of the skin. They arise from vascular, arrector pili, genital, and ... Genital leiomyoma is the least commonly occurring type of cutaneous leiomyoma, and data to establish its various ...
  https://www.hindawi.com/journals/cris/2013/475215/
*  Familial renal disease in animals - Wikipedia
It is sometimes accompanied by nodules in the skin or multiple uterine leiomyomas. Lhasa Apsos and Shih Tzus can both be ...
  https://en.wikipedia.org/wiki/Familial_renal_disease_in_animals
*  Leiomyoma - WOW.com
Skin. Leiomyomas of the skin are generally (1) acquired, and (2) divided into several categories:[5][6] ... Uterine fibroids are leiomyomata of the uterine smooth muscle. As other leiomyomata, they are benign, but may lead to excessive ... Familial leiomyoma. *Associated with papillary variant of renal cell carcinoma and multiple cutaneous leiomyoma. Defect is in ... Other locations, metastatic leiomyoma. * Metastatic leiomyoma are an extremely rare complication after surgery to remove the ...
  http://www.wow.com/wiki/Leiomyoma?s_pt=aolsem&s_chn=9
*  Risk Factors and Prevention
... is associated with an increased risk of developing type 2 papillary renal cell carcinoma and skin nodules called leiomyomata ... Birt-Hogg-Dubé syndrome (BHD). BHD is a rare genetic condition associated with multiple noncancerous skin tumors, lung cysts, ... Tuberous sclerosis complex (TSC). TSC is a genetic condition associated with changes in the skin, brain, kidney, and heart. ... Women with HLRCC often develop uterine fibroids known as leiomyomas or, less commonly, leiomyosarcoma. ...
  https://www.cancer.net/cancer-types/kidney-cancer/risk-factors-and-prevention
*  Diseases - PrimePCR | Life Science | Bio-Rad
Skin diseases - Papulosquamous. *Skin diseases - Vascular. *Skin diseases - Vesiculobullous. *Skin manifestations. *Skin ulcer ...
  http://www.bio-rad.com/en-us/prime-pcr-assays/pathway/diseases