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*  Interleukin 5 receptor alpha subunit - Wikipedia
"Attenuation of IL-5-mediated signal transduction, eosinophil survival, and inflammatory mediator release by a soluble human IL- ... The receptor is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for ... Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 ... Interleukin 5 receptor alpha subunit has been shown to interact with: Interleukin 5, Janus kinase 2, Protein unc-119 homolog, ...
  https://en.wikipedia.org/wiki/Interleukin_5_receptor_alpha_subunit
*  Interleukin 15 receptor, alpha subunit - Wikipedia
The shared subunits contain the cytoplasmic motifs required for signal transduction, and this forms the basis of many ... Interleukin 15 receptor, alpha subunit is a subunit of the interleukin 15 receptor that in humans is encoded by the IL15RA gene ... The IL-15 receptor is composed of three subunits: IL-15R alpha, CD122, and CD132. Two of these subunits, CD122 and CD132, are ... "IL-2 and IL-15 receptor alpha-subunits are coexpressed in a supramolecular receptor cluster in lipid rafts of T cells". Proc. ...
  https://en.wikipedia.org/wiki/Interleukin_15_receptor,_alpha_subunit
*  Interleukin-5 receptor - Wikipedia
The β-subunit of the IL-5 receptor is responsible for signal transduction and contains several intracellular signaling domains ... The interleukin-5 receptor is a type I cytokine receptor. It is a heterodimer of the interleukin 5 receptor alpha subunit and ... receptor alpha chain and its function in IL-5-mediated growth signal transduction". Mol. Cell. Biol. 14 (11): 7404-13. PMC ... "Signal transduction by the high-affinity GM-CSF receptor: two distinct cytoplasmic regions of the common beta subunit ...
  https://en.wikipedia.org/wiki/Interleukin-5_receptor
*  Interleukin 10 receptor, alpha subunit - Wikipedia
Donnelly RP, Dickensheets H, Finbloom DS (1999). "The interleukin-10 signal transduction pathway and regulation of gene ... Interleukin 10 receptor, alpha subunit is a subunit for the interleukin-10 receptor. IL10RA, is its human gene. IL10RA has also ... Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Interleukin 10 receptor, alpha subunit ... IL10RA interleukin 10 receptor, alpha". Ho AS, Liu Y, Khan TA, Hsu DH, Bazan JF, Moore KW (December 1993). "A receptor for ...
  https://en.wikipedia.org/wiki/Interleukin_10_receptor,_alpha_subunit
*  IL4R | Cancer Genetics Web
Other two subunits of IL-4R, interleukin-13 receptor α1 (IL-13Rα1) and interleukin-2 receptor gamma (IL-2RγC), were either ... receptor signaling protein activity - regulation of cell proliferation - response to estrogen stimulus - signal transduction ... This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and ... After forming ligand-receptor complexes, both cytokines initiate signal transduction and mediate biological effects, such as ...
  http://www.cancerindex.org/geneweb/IL4R.htm
*  Interleukin-9 receptor - Wikipedia
1998). "Heteromerization of the gammac chain with the interleukin-9 receptor alpha subunit leads to STAT activation and ... Knoops L, Renauld JC (2005). "IL-9 and its receptor: from signal transduction to tumorigenesis". Growth Factors. 22 (4): 207-15 ... 2000). "14-3-3zeta interacts with the alpha-chain of human interleukin 9 receptor". Biochem. J. 345 Pt 3 (3): 741-7. doi: ... 1999). "Tip60 interacts with human interleukin-9 receptor alpha-chain". Biochem. Biophys. Res. Commun. 263 (1): 149-55. doi: ...
  https://en.wikipedia.org/wiki/Interleukin-9_receptor
*  Janus kinase 1 - Wikipedia
"Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways". J. ... 1993). "The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction". Nature. ... 1994). "Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits". Science. 266 (5187): 1045 ... Donnelly RP, Dickensheets H, Finbloom DS (1999). "The interleukin-10 signal transduction pathway and regulation of gene ...
  https://en.wikipedia.org/wiki/Janus_kinase_1
*  Targeting different domains of gap junction protein to control malignant glioma, Neuro-Oncology | 10.1093/neuonc/nox207 |...
... affecting downstream signal transduction and regulating the biological function of cells.9,10 It is worth noting that many of ... interleukin-1 beta; IP3, inositol triphosphate; NAD, nicotinamide adenine dinucleotide; TNF-α, tumor necrosis factor alpha; ... After T cells modified by this receptor enter the body, the receptor can be digested into 2 parts by the local high ... A) At the plasma membrane, functional hemichannels are composed of 6 connexin subunits to allow mass exchange between the cell ...
  https://www.deepdyve.com/lp/ou_press/targeting-different-domains-of-gap-junction-protein-to-control-31J92U1yXo
*  KEGG SSDB Best Search Result: stm:STM0928
oaa:100077806 interleukin 22 receptor subunit alpha 1 K05138 492 113 ( -) 32 0.312 112 ,-, 1 fae:FAES_3531 hypothetical protein ... hru:Halru_0509 signal transduction histidine kinase 656 127 ( -) 35 0.302 149 -, 1 sez:Sez_1425 sialidase NanA-like K01186 1546 ... bbag:E1O_22150 CheA signal transduction histidine kinas K02487.. 1829 104 ( -) 30 0.311 103 -, 1 cann:107866384 transcription ... ach:Achl_3385 Exo-alpha-sialidase K01186 558 242 ( 17) 61 0.251 275 ,-, 2 dfe:Dfer_3020 Exo-alpha-sialidase K01186 388 242 ...
  http://www.kegg.jp/ssdb-bin/ssdb_best?org_gene=stm:STM0928
*  PIK3R1 - Wikipedia
"The CBL-related protein CBLB participates in FLT3 and interleukin-7 receptor signal transduction in pro-B cells". J. Biol. Chem ... Phosphatidylinositol 3-kinase regulatory subunit alpha is an enzyme that in humans is encoded by the PIK3R1 gene. ... "Phosphatidylinositol 3-kinase in interleukin 1 signaling. Physical interaction with the interleukin 1 receptor and requirement ... Serve H, Hsu YC, Besmer P (1994). "Tyrosine residue 719 of the c-kit receptor is essential for binding of the P85 subunit of ...
  https://en.wikipedia.org/wiki/PIK3R1
*  Enhanced Interleukin (IL)-13 Responses in Mice Lacking IL-13 Receptor α 2 | JEM
... an essential component for binding and internalization but not for interleukin-13-induced signal transduction through the STAT6 ... Interleukin-13 receptor alpha′ but not alpha chain: a functional component of interleukin-4 receptors. Blood. 91:3884-3891. ... Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 ... cDNA cloning and characterization of the human interleukin 13 receptor alpha chain. J. Biol. Chem. 271:29265-29270. ...
  http://jem.rupress.org/content/197/6/703
*  GNAI3 - Wikipedia
"Alpha i-3 cDNA encodes the alpha subunit of Gk, the stimulatory G protein of receptor-regulated K+ channels". The Journal of ... Wu D, LaRosa GJ, Simon MI (Jul 1993). "G protein-coupled signal transduction pathways for interleukin-8". Science. 261 (5117): ... "Differential coupling of m2 and m4 muscarinic receptors to inhibition of adenylyl cyclase by Gi alpha and G(o)alpha subunits". ... and functional coupling of human 5-HT1A receptors to inhibitory G protein alpha-subunits and lack of coupling to Gs alpha". ...
  https://en.wikipedia.org/wiki/GNAI3
*  CD122 Antibody, FITC (Monoclonal, TM-b1 (TM-beta1))
... forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. ... The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity ... IL-2 receptor beta chain; IL-2 receptor subunit beta; IL-2/15 receptor-beta; IL-2R subunit beta; IL-2RB; Interleukin-2 receptor ... cytokine-mediated signaling pathway natural killer cell activation interleukin-2-mediated signaling pathway negative regulation ...
  https://www.thermofisher.com/antibody/product/CD122-Antibody-clone-TM-b1-TM-beta1-Monoclonal/11-1222-81
*  PLCB1 - 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 - Homo sapiens (Human) - PLCB1 gene & protein
4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. ... The receptor-mediated activation of PLC-beta-1 is mediated by two G-protein alpha subunits, alpha-Q and alpha-11. ... insulin-like growth factor receptor signaling pathway Source: BHF-UCL. *interleukin-12-mediated signaling pathway Source: BHF- ... regulation of retrograde trans-synaptic signaling by endocanabinoid Source: Ensembl. *signal transduction Source: UniProtKB ,p> ...
  https://www.uniprot.org/uniprot/Q9NQ66
*  Gene expression profiling of liver from dairy cows treated intra-mammary with lipopolysaccharide | BMC Genomics | Full Text
Our findings suggest that APR in the liver is triggered by the activation of signaling pathways that are involved with common ... Yoshioka M, Ito T, Miyazaki S, Nakajima Y: The release of tumor necrosis factor-alpha, interleukin-1, interleukin-6 and ... and the component of receptor pathway such as TOLLIP, which is an essential element of the IL-1 receptor signaling pathway [23 ... In addition, SOCS2 and SOCS3, the attenuator of STAT3 mediated signal transduction, were also altered. ...
  https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-9-443
*  Warner Greene, MD, PhD | UCSF-Gladstone Center for AIDS Research (CFAR)
The human interleukin-2 receptor: insights into subunit structure and growth signal transduction. Semin Immunol. 1990 Mar; 2(2 ... Regulation of interleukin 2 receptor alpha subunit (Tac or CD25 antigen) gene expression: binding of inducible nuclear proteins ... Distinct tyrosine residues within the interleukin-2 receptor beta chain drive signal transduction specificity, redundancy, and ... Analysis of interleukin-2-dependent signal transduction through the Shc/Grb2 adapter pathway. Interleukin-2-dependent ...
  https://cfar.ucsf.edu/people/warner-greene
*  SIGNAL transduction Flashcards by Lorne Runge | Brainscape
... arginine vasopressin receptors-3, Promiscuous receptors include:. IL1R1 (interleukin 1 receptor 1 binds IL-1 alpha and beta, ... IL-5 receptor is CD125 (IL5RA) and beta subunit CD131 .. These receptors transmit a signal due to ability to bind JAK kinase ... Tyrosine kinase receptor families including receptors for:. EGF, insulin receptor, PDGF receptor, FGF receptor, HGF (hepatic ... TIR (Toll IL-1 Receptor). TRAF1 (TNF receptor-associated factor 1). IRAK1 (interleukin-1 receptor-associated kinase 1). AP-1 ( ...
  https://www.brainscape.com/flashcards/signal-transduction-4207777/packs/4392200
*  Mouse IL-2 Antibody AF-402-NA: R&D Systems
The receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes. The 55 ... Interleukin-2 (IL-2) is an O-glycosylated four alpha -helix bundle cytokine that has potent stimulatory activity for antigen- ... signal transduction is performed by both IL-2 R beta and gamma c. IL-2 is best known for its autocrine and paracrine activity ... Atherogenic effect of interleukin-2 and antiatherogenic effect of interleukin-2 antibody in apo-E-deficient mice.. Authors: ...
  https://www.rndsystems.com/products/mouse-il-2-antibody_af-402-na
*  Interleukin 11 - Wikipedia
As a signaling molecule, interleukin 11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; ... Signal specificity is provided by the IL-11Rα subunit. Signal transduction is initiated upon binding of IL-11 to IL-11Ralpha ... Barton VA, Hall MA, Hudson KR, Heath JK (2000). "Interleukin-11 signals through the formation of a hexameric receptor complex ... "Interleukin-11 receptor signaling is required for normal bone remodeling". Journal of Bone and Mineral Research. 20 (7): 1093- ...
  https://en.wikipedia.org/wiki/Interleukin_11
*  Caspase-14, an apoptotic protease, nucleic acids encoding and methods of use - Patent # 6432628 - PatentGenius
Hsu et al., "TRADD-TRAF2 and TRADD-FADD Interactions Define Two Distinct TNF Receptor 1 Signal Transduction Pathways," Cell 84 ... Srinivasula et al., "The Ced-3/Interleukin 1.beta. Converting Enzyme-like Homolog Mch6 and the Lamin-cleaving Enzyme Mch2.alpha ... Such subunits should be selected so that they bind either the large or small subunit of caspase-14 polypeptides to prevent ... Similarly, an antibody that binds to either the large subunit or the small subunit of a caspase-14 polypeptide, but not to the ...
  http://www.patentgenius.com/patent/6432628.html
*  Cytokine & Cytokine Receptor
Quality reagents of cytokines and their receptors: recombinant proteins, antibodies, ELISA kits, ORF cDNA clones. Big Cost ... causing recruitment of several intracellular adaptors to activate multiple signal transduction pathways for cell survival, ... Type II cytokine receptors are multimeric receptors composed of heterologous subunits, and are receptors mainly for interferons ... IL-6R alpha, SCFR, c-kit, etc. Other cytokine receptors include TNF receptor family, chemokine receptors, and TGF-beta ...
  http://www.sinobiological.com/non-canonical-wnt-pathway_Reagents-for_cytokine---receptor_signal.html
*  ADCY1 - Wikipedia
Journal of Receptor and Signal Transduction Research. 22 (1-4): 79-110. doi:10.1081/RRS-120014589. PMID 12503609. Tucholski J, ... alpha i-G alpha s chimeras define the function of alpha chain domains in control of G protein activation and beta gamma subunit ... "HIV-1 envelope protein gp41 modulates expression of interleukin-10 and chemokine receptors on monocytes, astrocytes and ... Patke CL, Shearer WT (May 2000). "gp120- and TNF-alpha-induced modulation of human B cell function: proliferation, cyclic AMP ...
  https://en.wikipedia.org/wiki/ADCY1
*  Frontiers | Interplay between Inflammation and Cellular Stress Triggered by Flaviviridae Viruses | Microbiology
RIG-I-like receptors (RIG-I and MDA5) and RNA-dependent protein kinases (PKR), inducing the production of inflammatory ... RIG-I-like receptors (RIG-I and MDA5) and RNA-dependent protein kinases (PKR), inducing the production of inflammatory ... Virus RNA molecules are sensed by Toll-like receptors (TLRs), ... Virus RNA molecules are sensed by Toll-like receptors (TLRs), ... the alpha-subunit of translation initiation factor eIF2-α (eIF2-alpha; Aguirre et al., 2012). This leads to the shutoff of ...
  https://www.frontiersin.org/articles/10.3389/fmicb.2016.01233/full
*  Cytokines
Type II cytokine receptors are multimeric receptors composed of heterologous subunits, and are receptors mainly for interferons ... adaptors to activate multiple signal transduction pathways for cell survival, death, and differentiation. Colony-stimulating ... IL-6R alpha, SCFR, c-kit, etc. Other cytokine receptors include TNF receptor family, chemokine receptors, and TGF-beta ... Interleukins are a group of cytokines that were first seen to be expressed by leukocytes. They modulate inflammation and ...
  https://www.novoprolabs.com/cytokines/
*  IL13RA2 - Wikipedia
Interleukin-13 receptor subunit alpha-2 (IL-13Rα2), also known as CD213A2 (cluster of differentiation 213A2), is a membrane ... 2006). "Level of expression of IL-13R alpha 2 impacts receptor distribution and IL-13 signaling". J. Immunol. 176 (12): 7495- ... IL13RA2 interleukin 13 receptor, alpha 2". Andrews AL, Nasir T, Bucchieri F, et al. (1996). "IL-13 receptor alpha 2: a ... 1998). "The murine IL-13 receptor alpha 2: molecular cloning, characterization, and comparison with murine IL-13 receptor alpha ...
  https://en.wikipedia.org/wiki/IL13RA2