*  serine-type endopeptidase activity Gene Ontology Term (GO:0004252)
The Gene Ontology (GO) project is a collaborative effort to address the need for consistent descriptions of gene products across databases. You can use this browser to view terms, definitions, and term relationships in a hierarchical display. Links to summary annotated gene data at MGI are provided in Term Detail reports.
  http://www.informatics.jax.org/vocab/gene_ontology/GO:0004252
*  Fibrinolysis - Wikipedia
When plasmin breaks down fibrin, a number of soluble parts are produced. These are called fibrin degradation products (FDPs). FDPs compete with thrombin, and thus slow down clot formation by preventing the conversion of fibrinogen to fibrin. This effect can be seen in the thrombin clotting time (TCT) test, which is prolonged in a person that has active fibrinolysis.. FDPs, and a specific FDP, the D-dimer, can be measured using antibody-antigen technology. This is more specific than the TCT, and confirms that fibrinolysis has occurred. It is therefore used to indicate deep-vein thrombosis, pulmonary embolism, DIC and efficacy of treatment in acute myocardial infarction. Alternatively, a more rapid detection of fibrinolytic activity, especially hyperfibrinolysis, is possible with thromboelastometry (TEM) in whole blood, even in patients on heparin. In this assay, increased fibrinolysis is assessed by comparing the TEM profile in the absence or presence of the fibrinolysis inhibitor aprotinin. ...
  https://en.wikipedia.org/wiki/Fibrinolysis
*  Drotrecogin alfa - Wikipedia
Drotrecogin alpha (activated) belongs to the class of serine proteases. Drotrecogin alfa has not been found to improve outcomes ...
  https://en.wikipedia.org/wiki/Drotrecogin_alfa
*  USRE38431E1 - Methods of production and use of liquid formulations of plasma proteins - Google Patents
A61K38/482-Serine endopeptidases (3.4.21) * A61K38/4846-Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); ... Five of the six vitamin K-dependent plasma proteins are serine proteases upon activation. These proteases have histidine, ... aspartic acid, and serine residues in analogous positions within their catalytic domains. Protein S is a cofactor for Protein C ... serine. serine. serine. serine. serine. cofactor. protease. protease. protease. protease. protease. Protein. ...
  https://patents.google.com/patent/USRE38431E1/en
*  Comparison of cytokine production by PBMCs from differe | Open-i
Serine Endopeptidases/metabolism/pharmacology*. Minor. *Adjuvants, Immunologic/pharmacology. *Granulocyte-Macrophage Colony- ... A characteristic of human pathogenic Neisseriae is the production and secretion of an immunoglobulin (Ig)A1-specific serine ... A characteristic of human pathogenic Neisseriae is the production and secretion of an immunoglobulin (Ig)A1-specific serine ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2195656_JEM990695.f2&req=4
*  Pancreatic elastase - Wikipedia
Pancreatic elastase 1 is a serine endopeptidase, a specific type of protease that has the amino acid serine at its active site ... Studies of human pancreatic elastase 1 have shown that this serine protease maps to the chromosomal region 12q13 and it is ... Elastases form a subfamily of serine proteases, characterized by a distinctive structure consisting of two beta barrel domains ... or serine elastase. The first isozyme, pancreatic elastase 1, was initially thought to be expressed in the pancreas. However it ...
  https://en.wikipedia.org/wiki/Pancreatic_elastase
*  List of MeSH codes (D08) - Wikipedia
... serine endopeptidases MeSH D08.811.277.656.300.760.030 --- acrosin MeSH D08.811.277.656.300.760.176 --- chymotrypsin MeSH ... endopeptidase clp MeSH D08.811.277.656.149.500 --- protease la MeSH D08.811.277.656.300 --- endopeptidases MeSH D08.811.277.656 ... endopeptidase clp MeSH D08.811.277.656.300.760.247 --- endopeptidase k MeSH D08.811.277.656.300.760.284 --- enteropeptidase ... Serine-type D-Ala-D-Ala carboxypeptidase MeSH D08.811.277.656.350.245.280 --- gamma-glutamyl hydrolase MeSH D08.811.277.656. ...
  https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D08)
*  Subtilisin - Wikipedia
... serine endopeptidase). The structure of subtilisin has been determined by X-ray crystallography. It is a 275-residue globular ... Subtilisins belong to subtilases, a group of serine proteases that - like all serine proteases - initiate the nucleophilic ... It is structurally unrelated to the chymotrypsin-clan of serine proteases, but uses the same type of catalytic triad in the ... Polgár L (1987). "Structure and function of serine proteases". In Brocklehurst K; Neuberger A. Hydrolytic enzymes. Amsterdam: ...
  https://en.wikipedia.org/wiki/Subtilisin
*  List of EC numbers (EC 3) - Wikipedia
Pancreatic endopeptidase E EC 3.4.21.71: Pancreatic elastase II EC 3.4.21.72: IgA-specific serine endopeptidase EC 3.4.21.73: u ... Ste24 endopeptidase EC 3.4.24.85: S2P endopeptidase EC 3.4.24.86: ADAM 17 endopeptidase EC 3.4.24.87: ADAMTS13 endopeptidase EC ... ADAM10 endopeptidase EC 3.4.24.82: ADAMTS-4 endopeptidase EC 3.4.24.83: anthrax lethal factor endopeptidase EC 3.4.24.84: ... Now considered EC 3.4.21.25, cucumisin EC 3.4.21.57: Leucyl endopeptidase EC 3.4.21.58: Deleted entry: prohormone serine ...
  https://en.wikipedia.org/wiki/List_of_EC_numbers_(EC_3)
*  Glutamyl endopeptidase I - Wikipedia
S. epidermidis glutamyl endopeptidase GluSE Also called S. epidermidis serine protease (Esp). S. warneri glutamyl endopeptidase ... subtilis glutamyl endopeptidase GluBS Enterococcus E. faecalis glutamyl endopeptidase SprE Glutamyl endopeptidase is in at ... Glutamyl endopeptidase I is a family of extracellular bacterial serine proteases. The proteases within this family have been ... purification and characterization of isoforms of an extracellular serine glutamyl endopeptidase of Enterococcus faecalis with ...
  https://en.wikipedia.org/wiki/Glutamyl_endopeptidase_I
*  Endopeptidase So - Wikipedia
Endopeptidase So (EC 3.4.21.67, E. coli cytoplasmic proteinase, proteinase So, Escherichia coli serine proteinase So) is an ... Endopeptidase So at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and Cellular Biology portal. ... Chung, C.H.; Goldberg, A.L. (1983). "Purification and characterization of protease So, a cytoplasmic serine protease in ... or Bz-Arg-OEt This is an Escherichia coli cytoplasmic endopeptidase. Goldberg, A.L.; Swamy, K.H.S.; Chung, C.H.; Larimore, F.S ...
  https://en.wikipedia.org/wiki/Endopeptidase_So
*  Endopeptidase La - Wikipedia
Endopeptidase La (EC 3.4.21.53, ATP-dependent serine proteinase, lon proteinase, protease La, proteinase La, ATP-dependent lon ... Endopeptidase La at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and Cellular Biology portal. ... serine protease La) is an enzyme. This enzyme catalyses the following chemical reaction Hydrolysis of proteins in presence of ... proteinase, ATP-dependent protease La, Escherichia coli proteinase La, Escherichia coli serine proteinase La, gene lon protease ...
  https://en.wikipedia.org/wiki/Endopeptidase_La
*  Pancreatic endopeptidase E - Wikipedia
Pancreatic endopeptidase E (EC 3.4.21.70, cholesterol-binding proteinase, proteinase E, cholesterol-binding serine proteinase, ... Pancreatic endopeptidase E at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and Cellular ...
  https://en.wikipedia.org/wiki/Pancreatic_endopeptidase_E
*  ATP-dependent Clp protease proteolytic subunit - Wikipedia
This protein is an essential component to form the protein complex of Clp protease (Endopeptidase Clp). Enzyme ClpP is a highly ... conserved serine protease present throughout bacterial and also found in the mitochondria and chloroplasts of eukaryotic cells ... CLP protease family Endopeptidase Clp Protease Transfer-messenger RNA GRCh38: Ensembl release 89: ENSG00000125656 - Ensembl, ...
  https://en.wikipedia.org/wiki/ATP-dependent_Clp_protease_proteolytic_subunit
*  FUSION PROTEINS - Patent application
0121] The protease of the present invention preferably demonstrates a serine or metalloprotease activity (e.g. endopeptidase ... Preparation of a Nociceptin Variant Targeted Endopeptidase Fusion Protein Containing a LC Domain Derived from Tetanus Toxin [ ... Preparation and Assessment of a Nociceptin Targeted Endopeptidase Fusion Protein with a Removable Histidine Purification Tag [ ... 0189] The in vitro endopeptidase activity of the purified LC/A-nociceptin-HN/A fusion protein was determined essentially as ...
  http://www.patentsencyclopedia.com/app/20120064059
*  HGFAC - Hepatocyte growth factor activator - Homo sapiens (Human) - HGFAC gene & protein
serine-type endopeptidase activity Source: InterPro. View the complete GO annotation on QuickGO ... ... Hydrolase, Protease, Serine proteaseUniRule annotation. ,p>Information which has been generated by the UniProtKB automatic ...
  http://www.uniprot.org/uniprot/D6RAR4
*  MK5 Microarray Data
Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase ... RNA-binding motif and serine/arginine rich protein 2) (Renal carcinoma antigen NY-REN-20). [Uniprot/SWISSPROT;Acc:Q15696] ...
  http://analysis.yellowcouch.org/mk5/?pid=4867&focus=0,7,59
*  protein - Everything2.com
Serine Protease. *caspase. *endopeptidase. *Pepsin. *transferases: *chloramphenicol acetyl transferase (n). *hypoxanthine- ...
  https://everything2.com/title/PROTEIN
*  MEROPS - Arabidopsis lyrata
Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases. ... Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs. ... Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence. ... Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane. ...
  https://genome.jgi.doe.gov/mycocosm/annotations/browser/merops/summary
*  WikiGenes - PIK3CB - phosphatidylinositol-4,5-bisphosphate 3...
Regulation of phosphoinositide 3-kinase by its intrinsic serine kinase activity in vivo. Foukas, L.C., Beeton, C.A., Jensen, J ... Detection of the p110 beta subunit of phosphatidylinositol 3-kinase complexed with neutral endopeptidase. Shen, R., Milowsky, M ... Myogenic signaling of phosphatidylinositol 3-kinase requires the serine-threonine kinase Akt/protein kinase B. Jiang, B.H., ... Detection of the p110 beta subunit of phosphatidylinositol 3-kinase complexed with neutral endopeptidase [25]. ...
  https://www.wikigenes.org/e/gene/e/5291.html
*  Cardiometabolic panel
the Cardiometabolic panel uses a 1:2025 dilution of sample, whereas our technical validation assays are performed in vitro using recombinant analytes. Technical validation data reported on the biomarker pages below, and in the data validation document for this panel are based on these in vitro assays. A multiplication factor of 2025 should therefore be taken into consideration when comparing the addressable biological concentration to the in vitro validation data. You can download the Sample Dilution Guideline for this panel here.. A comprehensive list of all protein biomarkers that can be measured using the currently available biomarker panels can be seen on the biomarker library page.. Note: A printable list of the biomarker assays available in this panel, as well as a full data validation document, can be downloaded from our Document download center ,,. If you prefer not to run the assay yourself, let our experts here at Olink do this for you via our Analysis Service.. The biomarker pages ...
  http://www.olink.com/products/cardiometabolic-panel/
*  US7048927B2 - Botulinum neurotoxin eluting stent - Google Patents
Inhibiting Aberrant Blood Vessel Formation Using Retargeted Endopeptidases EP2694150A1 (en) 2011-04-08. 2014-02-12. Covidien LP ... serine, threonine, valine, tryptophan, tyrosine and other naturally occurring amino acids as well as non-standard amino acids. ... or a fragment of the L chain containing the endopeptidase activity, is expressed recombinantly as a fusion protein with the HN ... or a fragment of the L chain containing the endopeptidase activity, is expressed recombinantly to produce an agent for use in ...
  https://patents.google.com/patent/US7048927
*  Pharmacotherapy for Pulmonary Hypertension: Future Directions
Combined tyrosine and serine/threonine kinase inhibition by sorafenib prevents progression of experimental pulmonary ... of the effects of vasoactive intestinal peptide aerosol on pulmonary hypertension via coapplication of a neutral endopeptidase ... Complete reversal of fatal pulmonary hypertension in rats by a serine elastase inhibitor. Nat Med 2000;6:698-702. ...
  https://www.jbclinpharm.org/articles/pharmacotherapy-for-pulmonary-hypertension-future-directions-4158.html
*  KEGG SSDB Best Search Result: gps:C427 4907
nfa:NFA_18440 putative serine/threonine protein kinase K12132 531 105 ( -) 30 0.329 82 -, 1 nfr:ERS450000_02269 Serine/ ... rto:RTO_29320 O-sialoglycoprotein endopeptidase K01409 342 113 ( -) 32 0.312 80 -, 1 ure:UREG_05900 hypothetical protein K21864 ... ncy:NOCYR_1995 putative serine/threonine protein kinase K12132 502 100 ( -) 29 0.300 100 -, 1 nfl:COO91_04825 ABCB-BAC, ATP- ... nsl:BOX37_09480 serine/threonine protein kinase 499 100 ( -) 29 0.329 82 -, 1 pnl:PNK_0288 ABC transporter ATP-binding protein ...
  http://www.kegg.jp/ssdb-bin/ssdb_best?org_gene=gps:C427_4907