*  Nonribosomal peptide - Wikipedia
Antibiotics Actinomycin Bacitracin Calcium dependent antibiotic Daptomycin Vancomycin Teixobactin Tyrocidine Gramicidin ...
  https://en.wikipedia.org/wiki/Nonribosomal_peptide
*  Tyrocidine - Wikipedia
It can be composed of 4 different amino acid sequences, giving tyrocidine A-D (See figure 1). Tyrocidine is the major ... The exact affinity and location of tyrocidine within the phospholipid bilayer is not yet known. The biosynthesis of Tyrocidine ... The function of tyrocidine within its host B. brevis is thought to be regulation of sporulation. Tyrocidines A, B, and C are ... Tyrocidine has a unique mode of action in which it disrupts the cell membrane function, making it a favorable target for ...
  https://en.wikipedia.org/wiki/Tyrocidine
*  The amino-acid composition of tyrocidine | Biochemical Journal
The amino-acid composition of tyrocidine. A. H. Gordon, A. J. P. Martin, R. L. M. Synge ...
  http://www.biochemj.org/content/37/3/313
*  Antibiotic - Wikipedia
Tyrocidine also proved too toxic for systemic usage. Research results obtained during that period were not shared between the ... tyrocidine, from B. brevis. It was one of the first commercially manufactured antibiotics and was very effective in treating ...
  https://en.m.wikipedia.org/wiki/Antibiotic
*  ASMscience | Assembly of Peptide Anti
The tyrocidine system is particularly well understood with respect to variants of the product that exhibit amino acid ... Biosynthesis of tyrocidine by a cell-free enzyme system of Bacillus brevis ATCC 8185. II. Amino acid substitution in tyrocidine ... The chemistry of tyrocidine. I. Isolation and characterization of a single peptide. J. Am. Chem. Soc. 74:4019-4023.. ... Tyrocidine biosynthesis by three complementary fractions from Bacillus brevis ATCC 8185. Biochemistry 9:4839-4845.. ...
  http://www.asmscience.org/content/book/10.1128/9781555817992.chap30
*  Brevibacillus brevis - Wikipedia
The antibiotics gramicidin and tyrocidine were first isolated from it. Brevibacillus brevis forms Gram-positive (variable) rods ...
  https://en.wikipedia.org/wiki/Brevibacillus_brevis
*  Amino acid - Wikipedia
Other compounds containing D-amino acid are tyrocidine and valinomycin. These compounds disrupt bacterial cell walls, ...
  https://en.wikipedia.org/wiki/Amino_acid
*  Sequencing Antibiotics by Shattering Them into Pieces - Week 3: Sequencing Antibiotics | Coursera
We know the sequence of Tyrocidine B1, so we just need to go through and ... So the question then, is, well, what's the mass of something like Tyrocidine B1? ...
  https://www.coursera.org/learn/genome-sequencing/lecture/NtF2a/sequencing-antibiotics-by-shattering-them-into-pieces
*  Patent US6642357 - Process for preparing modified proteins - Google Patents
Roskoski, et al., "Isolation of Enzyme-Bound Peptide Intermediates in Tyrocidine Biosynthesis", Biochemistry 9: 4846-4851 (1970 ...
  http://www.google.com/patents/US6642357?dq=5,266,072
*  Asymmetric Stetter reactions catalyzed by thiamine diphosphate-dependent enzymes | SpringerLink
Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase. Nature 407:215-218. doi: 10.1038/35025116 ...
  https://link.springer.com/article/10.1007%2Fs00253-014-5850-0
*  Genome comparison of two Magnaporthe oryzae field isolates reveals genome variations and potential virulence effectors | BMC...
Rice blast caused by the fungus Magnaporthe oryzae is an important disease in virtually every rice growing region of the world, which leads to significant annual decreases of grain quality and yield. To prevent disease, resistance genes in rice have been cloned and introduced into susceptible cultivars. However, introduced resistance can often be broken within few years of release, often due to mutation of cognate avirulence genes in fungal field populations. To better understand the pattern of mutation of M. oryzae field isolates under natural selection forces, we used a next generation sequencing approach to analyze the genomes of two field isolates FJ81278 and HN19311, as well as the transcriptome of FJ81278. By comparing the de novo genome assemblies of the two isolates against the finished reference strain 70-15, we identified extensive polymorphisms including unique genes, SNPs (single nucleotide polymorphism) and indels, structural variations, copy number variations, and loci under strong
  https://0-bmcgenomics-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/1471-2164-14-887
*  Rollin Hotchkiss - Wikipedia
Their work on gramicidin and tyrocidine led to the first commercial antibiotics, and with Fritz Lipmann they found that the ...
  https://en.wikipedia.org/wiki/Rollin_Hotchkiss
*  Gramicidin - Wikipedia
... and tyrocidine (80%). These were the first antibiotics to be manufactured commercially. Gramicidin is a polypeptide with ...
  https://en.wikipedia.org/wiki/Gramicidin
*  Enzyme promiscuity - Wikipedia
... from Bacillus brevis adenylates a molecule of phenylalanine in order to use the adenyl moiety as a handle to produce tyrocidine ... the first subunit of tyrocidine synthetase (tyrA) ...
  https://en.wikipedia.org/wiki/Enzyme_promiscuity
*  7 Literatur - PDF
130, 747 Mootz, H. and Marahiel, M.A. (1997a). The tyrocidine biosynthetase operon of Bacillus brevis: complete nucleotide ... 224, Pfeifer, E., Pavela-Vrancic, M. von Döhren, H. and Kleinkauf, H. (1995). Characterization of tyrocidine synthetase 1 (TY1 ... 1971). Polypeptide synthesis on protein templates: the enzymatic synthesis of gramicidin S and tyrocidine. Adv. Enzymol. Relat ... The adenylation domain of tyrocidine synthetase 1. Eur. J. Biochem. 247, Dieckmann, R., Pavela-Vrancic, M., von Döhren, H. and ...
  http://docplayer.net/659861-7-literatur-177-284-233-262.html
*  antibiotic facts, information, pictures | Encyclopedia.com articles about antibiotic
Tyrothricin, a mixture of the two peptides gramicidin and tyrocidine, was also found to be toxic to red blood and reproductive ...
  https://www.encyclopedia.com/medicine/drugs/pharmacology/antibiotic
*  Team:Heidelberg/Project Software - 2013.igem.org
Figure 3: Domain border prediction. Upper panel: Clustal Omega MSA of different C-A domain borders of Tyrocidine cluster with ... We chose the Maryland HMM, because it agreed most with our Tyrocidine experiments, as well as previously published results [14] ... C-A domain boundary based on Tyrocidine results). Finally, the Indigoidine tag was included in the software only, once its ...
  http://2013.igem.org/Team:Heidelberg/Project_Software
*  The Discovery of Antibiotics - Week 3: Sequencing Antibiotics | Coursera
what the sequence of amino acids in Tyrocidine B1 really is.. And so that question is what we're going to talk about today, ...
  https://tr.coursera.org/learn/genome-sequencing/lecture/KJcfp/the-discovery-of-antibiotics
*  Fritz Albert Lipmann | Biographical Memoirs: Volume 88 | The National Academies Press
... he showed that cyclic peptide antibiotics such as gramicidin and tyrocidine are synthesized by the sequential addition of amino ...
  https://www.nap.edu/read/11807/chapter/14
*  Patente US5112614 - Implantable delivery dispenser - Google Patentes
... tyrocidine, gramicidins, synthetic analogues, modifications and pharmaceutically-active fragments of polypeptides, monoclonal ...
  http://www.google.es/patents/US5112614?dq=flatulence&hl=es&output=html_text