The Calcium Sensitivity of Individual Secretory Vesicles Is Invariant with the Rate of Calcium Delivery | JGP
The Calcium Sensitivity of Individual Secretory Vesicles Is Invariant with the Rate of Calcium Delivery. Paul S. Blank, Steven ... In summary, we have determined that the calcium sensitivity of individual secretory vesicles is invariant with the rate of ... The calcium sensitivity of individual secretory vesicles was invariant to calcium delivery rates from faster than micromolar ... The Calcium Sensitivity of Individual Secretory Vesicles Is Invariant with the Rate of Calcium Delivery ...http://jgp.rupress.org/content/112/5/569
Functional and morphological plasticity of crocodile (Crocodylus porosus) salt glands | Journal of Experimental Biology
The highest rate of secretion achieved over the 40 min period was deemed the maximal secretory rate. Mass and maximal secretory ... maximal secretory rates, and tissue metabolic rate in C. porosus salt glands following prolonged acclimation to both fresh and ... which enabled a significantly elevated rate of Na+ secretion. Maximal mean lingual gland secretory rates were more than three ... the salt glands of crocodiles exposed to hypersaline conditions have a greater secretory rate and higher tissue metabolic rate ...http://jeb.biologists.org/content/211/9/1482.full
Determination of PRL Secretory Rates. The secretory rates of PRL were derived from plasma concentrations using deconvolution ... PRL secretory rates were derived from plasma concentrations by deconvolution. Diurnal (24-h) variations were quantified by a ... The analysis of parameters quantifying the 24-h profiles of plasma PRL and PRL secretory rates in MZ and DZ twins permitted ... Deconvolution of plasma concentrations allowed us to estimate PRL secretory rates, and the following parameters characterizing ...http://ajpendo.physiology.org/content/274/5/E909
Variability of flow rate when collecting ... & related info | Mendeley
In healthy volunteers a strong correlation (r2 = 0.79) between flow rates f... ... Secretory Rate/drug effects/*physiology. *Sjogren's Syndrome/physiopathology. *Time Factors. Get free article suggestions today ... Thus, notwithstanding the good agreement between left and right flow rates, a high variation in parotid flow rates has to be ... Variability of flow rate when collecting stimulated human parotid saliva. *Burlage F ...https://www.mendeley.com/research-papers/variability-flow-rate-collecting-stimulated-human-parotid-saliva/
Cimetidine as an adjunct to oral enzymes in the treatment of malabsorption due to cystic fibrosis.
Secretory Rate / drug effects. Chemical. Reg. No./Substance: 0/Guanidines; 0/Lipids; 51481-61-9/Cimetidine; 7727-37-9/Nitrogen ...http://www.biomedsearch.com/nih/Cimetidine-as-adjunct-to-oral/6908433.html
Clinical Significance Of The Investigations Of Adrenal Cortical Disorders | HubPages
Secretory activity of the adrenal cortex: Cortisol secretory rate can be determined isotopically. Normal value is 250- 840 ... ACTH is infused intravenously for 8 hours at the rate of 5 U/hour and plasma levels of cortisol are estimated prior to and ...https://hubpages.com/health/Clinical-Significance-Of-The-Investigations-Of-Adrenal-Cortical-Disorders
Hyponatraemia with Metformin
Change in Insulin Secretory Rates; Change in Fasting Plasma Lipids; Change in HbA1c; Change in HOMA-IR; Change In 7-Point ... Clinical response rate; Pathologic complete response rate; Changes of Ki67(%); Breast conservation rate; Breast density change ... Response Rate; Toxicity evaluation; Patient Compliance; Potential molecular markers in response to treatment with Metformin. ...http://patientsville.com/i.htm?q=HYPONATRAEMIA&mp=Metformin
Search of: 'Zollinger-Ellison Syndrome' - List Results - ClinicalTrials.gov
Control is defined as gastric acid secretory rate below 10 mEq/h or below 5 meq/h for patients with prior gastric acid reducing ... The status (controlled or not controlled) of gastric acid secretory rate at the Month 6 study visit. ... To assess the gastric acid secretory rate at the final study visit. ... Objective Response Rate. 46. All. 18 Years and older (Adult, Senior). NCT00427349. CDR0000526256. ECOG-E4206. U10CA023318. ...https://clinicaltrials.gov/ct2/results?cond=%22Zollinger-Ellison+Syndrome%22&show_flds=Y
Gonadotropin | definition of gonadotropin by Medical dictionary
Secretory rates of human chorionic gonadotropin by normal trophoblast.. The long gestation of the modern home pregnancy test ...https://medical-dictionary.thefreedictionary.com/gonadotropin
Cimetidine Injection - FDA prescribing information, side effects and uses
These doses maintained the intragastric acid secretory rate at 10 mEq/hour or less. The infusion rate should be adjusted to ... Active Duodenal Ulcer: Cimetidine accelerates the rate of duodenal ulcer healing. Healing rates reported in U.S. and foreign ... Blood levels with other infusion rates will vary in direct proportion to the infusion rate. ... In a similar multicenter U.S. study of the 800 mg h.s. oral regimen, the endoscopically confirmed healing rates were:. ...https://www.drugs.com/pro/cimetidine-injection.html
3, bottom). On removal of the drug from the perfusate, a decrease in the insulin secretory rate was noticed. Under the same ... The secretory capacity of BM 225 was more marked than that of BM 208, but the time courses of the cationic and secretory ... fractional outflow rate. [Ca2+]i. intracellular Ca2+ concentration. KATP+. ATP-sensitive K+ BM 225. 1-[4-(5-chloro-2- ... 2, top). The capacity of 10 μM BM 208 and 10 μM BM 225 to inhibit the86Rb outflow rate was identical. Thus, the paired ...http://jpet.aspetjournals.org/content/289/2/625
Articles Added on September 29, 2012
In this study, we compared basal and stimulated gastric acid and duodenal HCO(3)- secretory rates in aged late generation ... ... Telomere shortening is associated with reduced duodenal HCO3- secretory but normal gastric ... ...http://www.biomedsearch.com/added/20120929-p13.html
Use of antidepressants in treatment of comorbid diabetes mellitus and depression as well as in diabetic neuropathy. - Semantic...
... response rate. Yet, there are positive reports concerning the SSRIs (paroxetine, citalopram, sertraline), as well as nefazodone ... Tricyclic antidepressant imipramine reduces the insulin secretory rate in islet cells of Wistar albino rats through a calcium ...https://www.semanticscholar.org/paper/Use-of-antidepressants-in-treatment-of-comorbid-and-Goodnick/a09e0e547efa152f678ccfdca0edfc8f4bed3a4c
Diuretics and drug elimination | Physics Forums - The Fusion of Science and Community
Again because elimination would be more related to GFR and secretory rate - which are unaffected by a diuretic.. If the drug ... Reason being that the elimination is linked to glomerular filtration rate rather than urine volume.. If the drug is freely ... Do diuretics increase the elimination rates of drugs by increasing the volume of urine excretion? ... then indeed a diuretic would speed filtrate transit time and may reduce drug absorption and may increase the elimination rate ...https://www.physicsforums.com/threads/diuretics-and-drug-elimination.552658/
Dephosphorylation - Wikipedia
... dephosphorylation of the membrane ATPases and proton pumps in the gastrointestinal tract leads to higher secretory rates of ... Components of the protein synthetic apparatus also undergo phosphorylation and dephosphorylation and thus regulate the rates of ... phosphorylation of elongation factor 2 during mitosis in transformed human amnion cells correlates with a decreased rate of ...https://en.wikipedia.org/wiki/Dephosphorylation
What is a 17aa steroid?
EE decreased the secretory rate maximum (SRM) of tauroursodeoxycholate, (-71%) and bromosulfophthalein (BSP; -60%), as well as ... Effects of carbon tetrachloride and Liv.52 on the clearance rate of 131I-Rose Bengal in rat liver (pdf). Dhawan, D., Goel, A., ...http://forums.rxmuscle.com/showthread.php?11212-What-is-a-17aa-steroid&s=dfb1d18bbab30672e4e4b0e448b4bdd4&p=319878&viewfull=1
Older Subjects With β-Cell Dysfunction Have an Accentuated Incretin Release, Journal of Clinical Endocrinology and Metabolism |...
We quantitated insulin sensitivity (Matsuda index) and insulin secretory rate (ISR) by deconvolution of C-peptide with the ... We quantitated insulin sensitivity (Matsuda index) and insulin secretory rate (ISR) by deconvolution of C-peptide with the ... Van Cauter E , Mestrez F , Sturis J , Polonsky KS . Estimation of insulin secretion rates from C-peptide levels. Comparison of ... Van Cauter E , Mestrez F , Sturis J , Polonsky KS . Estimation of insulin secretion rates from C-peptide levels. Comparison of ...https://www.deepdyve.com/lp/ou_press/older-subjects-with-cell-dysfunction-have-an-accentuated-incretin-7heIbGe2VR
Patent US20030119736 - Methods for improving islet signaling in diabetes mellitus and for its ... - Google Patents
10). The insulin secretory rate shifted from a basal 570 170 μU/min to over 2100 μU/min within two minutes of high glucose ... The shift from 4.4 to 8.8 mM glucose perfusate caused a 3.2-fold increase in insulin secretory rate in the pancreata from the ... A method for causing an effect in a mammal selected from the group consisting of decreasing the rate of chronic weight gain, ... Food and water intake decreased over the course of the experiment paralleling the decrease in the rate of weight gain as the ...http://www.google.com/patents/US20030119736?dq=5,646,839
NIOSHTIC-2 Publications Search - 00190467 - Studies on ultradian rhythmicity in human sleep and associated neuroendocrine...
... appeared to be due to differences in frequency and duration of secretory episodes and not to major changes in secretory rate. ... In the 3 hour cycle, cortisol output and secretory time were maximal for the first hour after awakening, were less for the ... Under a defined and stable sleep/wake 24 hour cycle, normal young adult subjects had an average of nine secretory episodes with ...https://www.cdc.gov/niosh/nioshtic-2/00190467.html
Autonomous sweat extraction and analysis applied to cystic fibrosis and glucose monitoring using a fully integrated wearable...
... peak secretory rate in response to stimulation, time to reach peak secretory rate, and time spent secreting at the peak rate. ( ... gave the optimal combination of a rapid onset of secretion with high secretory rate and sustained secretion at high rate that ... we were able to consistently achieve secretory rates in excess of 100 nL/min/cm2 and extract sufficient amounts of sweat for ... we can achieve different patterns of sweat-secretion rate. We characterized the induced sweat rate profiles as stimulated by ...http://www.pnas.org/content/114/18/4625.full
Slc26a6 regulates CFTR activity in vivo to determine pancreatic duct HCO3− secretion: relevance to cystic fibrosis - Wang -...
... were used to calculate the secretory rates in terms of pl/min/mm2 (B). Secretory rates were calculated for the 10 min intervals ... Secretory rates were also calculated for the 10 min intervals of incubating the ducts in HEPES- and HCO3−-buffered media and ... However, slc26a6 reduces the rate of activation of CFTR and the reduction in rate was more pronounced when the intensity of ... The rate of changes in pHi (ΔpH/min) was calculated and expressed as % of that of WT. The results are the mean±s.e. of at least ...http://onlinelibrary.wiley.com/doi/10.1038/sj.emboj.7601387/full
Five Stages of Evolving Beta-Cell Dysfunction During Progression to Diabetes | Diabetes
... the enzyme that controls the rate of glycolysis, thereby determining insulin secretory rates (12). Thus, very small elevations ... given the assumption that the β-cell death rate must be similar to β-cell birth rate, which is probably considerably less than ... To maintain this degree of specialization, the genes that are highly expressed in β-cells include those of the secretory ... Ward WK, Bolgiano DC, McKnight B, Halter JB, Porte D Jr: Diminished B cell secretory capacity in patients with noninsulin- ...http://diabetes.diabetesjournals.org/content/53/suppl_3/S16.full
Sphincter of Oddi dysfunction produces acute pancreatitis in the possum | Gut
Changes in pancreatic secretory rate, amylase output, histology scores, and pancreatic duct pressure were analysed using one ... The period in which the flow rate changes from a negative to a positive slope indicates the period of cessation of trans- ... As trans-sphincteric flow proceeds, the weight of the reservoir decreases and the rate of change (slope) represents trans- ... Trans-sphincteric flow was measured by the rate of emptying of the reservoir containing saline. Partial/complete obstruction of ...http://gut.bmj.com/content/47/4/539
Reelin - Wikipedia
... being stored in Golgi secretory vesicles. Reelin's release rate is not regulated by depolarization, but strictly depends on its ... Studies show that reelin is absent from synaptic vesicles and is secreted via constitutive secretory pathway, ... synthesis rate. This relationship is similar to that reported for the secretion of other extracellular matrix proteins.[ ...https://en.wikipedia.org/wiki/Reelin
Sweat gland - Wikipedia
When the rate of sweating is low, salt is conserved and reabsorbed by the gland's duct; high sweat rates, on the other hand, ... Their secretory portion has a narrow portion similar to secretory coils in eccrine glands as well as a wide section reminiscent ... the secretory coils are surrounded by contractile myoepithelial cells that function to facilitate excretion of secretory ... The secretory coil or base, is set deep in the lower dermis and hypodermis, and the entire gland is surrounded by adipose ...https://en.wikipedia.org/wiki/Sweat_gland