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*  Functional manganese requirement and its use as a critical value for diagnosis of manganese deficiency in subterranean clover ...
The effects of manganese supply on plant growth and on photosynthesis and manganese concentrations in young leaves were examined in Seaton Park subterranean clover in three glasshouse water culture experiments.Plants werc grown initially with a copious supply of manganese, and transferred to solutions either with or without manganese. Sequential harvests were taken to determine the effects of developing manganese deficiency on dry matter (DM) yield of whole plants and selected characteristics [manganese, chlorophyll and photosynthetic oxygen evolution (POE)] of youngest open leaf blades (YOL). In addition, the deffect of leaf age and iron supply on POE werc examined.Manganese concentrations and POE in YOL declined markedly and rapidly in plants transferred to solutions without manganese, while chlorophyll concentrations of YOL and plant DM yield responded more weakly and more slowly. As a result, a level of manganese deficiency which depressed POE in young leaves by more than 50 per cent had no ...
  http://researchrepository.murdoch.edu.au/id/eprint/21070/
*  Manganese Deficiency Symptoms |IYTHEALTH.com
Manganese deficiency results in glucose intolerance similar to diabetes mellitus in some animal types, however studies analyzing the manganese status of diabetic human beings have created combined results. In one study, entire blood manganese levels did not vary substantially between 57 diabetics and 28 non-diabetic controls.. However, urinary manganese excretion tended to be a little higher in 185 diabetics compared to 185 non-diabetic controls. A case-control research study of 250 diabetic and non-diabetic people found that type 2 diabetic people had greater serum manganese levels than non-diabetics. Nevertheless, a more recent research study in 257 type 2 diabetics and 166 non-diabetic controls discovered lower blood levels of manganese in the diabetic patients.. Additionally, a study of practical manganese status found the activity of the antioxidant enzyme, MnSOD, was lower in the white blood cells of diabetics than in non-diabetics. Neither 15 mg nor 30 mg of oral manganese improved ...
  https://iythealth.com/manganese-deficiency-symptoms/
*  Manganese deficiency (medicine) - Wikipedia
Manganese is a component of some enzymes and stimulates the development and activity of other enzymes. Manganese superoxide dismutase (MnSOD) is the principal antioxidant in mitochondria. Several enzymes activated by manganese contribute to the metabolism of carbohydrates, amino acids, and cholesterol.[1]. A deficiency of manganese causes skeletal deformation in animals and inhibits the production of collagen in wound healing.[2]. Manganese is found in leafy green vegetables, fruits, nuts, cinnamon and whole grains. The nutritious kernel, called wheat germ, which contains the most minerals and vitamins of the grain, has been removed from most processed grains (such as white bread). The wheat germ is often sold as livestock feed. Many common vitamin and mineral supplement products fail to include manganese in their compositions. Relatively high dietary intake of other minerals such as iron, magnesium, and calcium may inhibit the proper intake of manganese.[3]. ...
  https://en.wikipedia.org/wiki/Manganese_deficiency_
*  Correlation of Manganese Contents of Soils and Wheat Plants (Triticum spelta) in the Cukurova Region of Turkey
Abstract: Correlation of Manganese Contents of Soils and Wheat Plants (Triticum spelta) in the Cukurova Region of Turkey
  http://scialert.net/abstract/?doi=pjbs.2008.2331.2335
*  Minerals ~ Manganese
Method of Action. Manganese is absorbed with about 4% efficiency from the intestines and is carried into, and in the blood by the protein transmanganin. Regulation of body manganese levels is controlled primarily through variable excretion, rather than absorption.. Manganese is essential for the enzymatic incorporation of xylose and galactose in glycoproteins. These glycoproteins are the cells natural barrier to invading viruses and coat every cell of the human body. Glycoproteins also make up the great majority of all secretory proteins.. Manganese and magnesium are used interchangeably in many enzymes as cofactors. Aminopeptidases, which break down protein structure, are secreted by the intestinal mucosal cells for digestive purposes and utilize either magnesium or manganese as the cofactor element of their structures.. Manganese is an important constituent of activated arginase, an enzyme found in the liver, and mediates the conversion of arginine to urea.. Manganese is a constituent of the ...
  http://www.springboard4health.com/notebook/min_manganese.html
*  The Symptoms of Manganese Deficiency | LIVESTRONG.COM
Manganese is a trace mineral that plays an important role in numerous biological processes throughout the body. It is nutritionally essential only in small...
  http://www.livestrong.com/article/485034-the-symptoms-of-manganese-deficiency/
*  Determinants of serum manganese levels in an Italian population. | Archivio della ricerca dell'Università di Modena e Reggio...
Manganese (Mn) is both essential and toxic for humans, mainly depending on the total levels and its species. Main sources of exposure include food and air pollution, particularly motorized traffic. We sought to determine the potential influence of these sources on serum total levels of Mn and Mn species. We selected a random sample of municipality residents from an Italian urban municipality, from whom we collected detailed personal information, dietary habits and a blood sample for serum Mn determination. We also assessed outdoor air Mn exposure, by modeling levels of particulate matter ≤10 µm (PM10) from motorized traffic at the residence of geocoded subjects. Serum Mn species generally showed higher levels in males and positive correlation with age, while no such differences were found according to smoking habits or use of dietary supplements. Among nutrients, only iron intake showed a relation with Mn [an inverse correlation with Mn‑ferritin (Mn‑Fer) and a direct one with ...
  https://iris.unimore.it/handle/11380/1133091
*  Kids with higher manganese levels may have lower IQ scores | The Siasat Daily
Manganese is an element generally found in combination with iron and many minerals.. It plays a vital role in brain growth and development, but excessive exposure can result in neurotoxicity.. Lead author Erin Haynes from the University of Cincinnati's academic health center in Ohio, U.S said that there are socioeconomic issues at play, however, they are also compounded by potentially significant environmental exposures.. "Children may be particularly susceptible to the neurotoxic effects of ambient Mn exposure, as their brains are undergoing a dynamic process of growth and development," Haynes added.. The results appear online in the journal NeuroToxicology. (ANI). ...
  https://www.siasat.com/news/kids-higher-manganese-levels-may-lower-iq-scores-1235655/
*  The Healing Properties of Tears: 7 Good Reasons to Cry Your Eyes Out - Beyond Blue
3. Tears remove toxins.. Biochemist William Frey, who has been researching tears for as long as I've been searching for sanity, found in one study that emotional tears-those formed in distress or grief-contained more toxic byproducts than tears of irritation (think onion peeling). Are tears toxic then? No! They actually remove toxins from our body that build up courtesy of stress. They are like a natural therapy or massage session, but they cost a lot less!. 4. Crying can elevate mood.. Do you know what your manganese level is? No, neither do I. But chances are that you will feel better if it's lower because overexposure to manganese can cause bad stuff: anxiety, nervousness, irritability, fatigue, aggression, emotional disturbance and the rest of the feelings that live inside my happy head rent-free. The act of crying can lower a person's manganese level. And just like with the toxins I mentioned in my last point, emotional tears contain 24 percent higher albumin protein ...
  http://www.beliefnet.com/columnists/beyondblue/2011/02/7-ways-tears-and-crying-heal.html?source=NEWSLETTER&nlsource=54&ppc=&u
*  Manganese - A Missing Link in Bone Health? - Mineralife Nutraceuticals, LLC
Your dentist and your doctor always told you to get plenty of Calcium for strong bones and teeth, but did they ever mention Manganese? Not likely, as Manganese is a hidden actor in the play for strong bones and teeth. In fact, the human body only needs 50 mg of Manganese, but those 50mg are absolutely essential for health. Without sufficient Manganese, you may experience porous bones, bone loss, and even bone disease such as osteoporosis. Not only that, Manganese deficiency can cause bow legs, poorly developed cartilage, loss of muscle coordination, and even nerve message transmission failure.This last problem, involving nerve message transmission, just may be the most dangerous of the effects. Muscles are commanded on proper functioning by the use of nerve fibers called neurotransmitters. This is something which occurs at the speed of lightning, enabling you to function normally. Every activity in the body, from the heart beating to legs running to typing on a keyboard is regulated by
  http://mineralifeonline.com/blog/manganese-a-missing-link-in-bone-health/
*  The role of the Parkinson's disease gene PARK9 in essential cellular pathways and the manganese homeostasis network in yeast |...
YPK9 (Yeast PARK9; also known as YOR291W) is a non-essential yeast gene predicted by sequence to encode a transmembrane P-type transport ATPase. However, its substrate specificity is unknown. Mutations in the human homolog of YPK9, ATP13A2/PARK9, have been linked to genetic forms of early onset parkinsonism. We previously described a strong genetic interaction between Ypk9 and another Parkinson's disease (PD) protein alpha-synuclein in multiple model systems, and a role for Ypk9 in manganese detoxification in yeast. In humans, environmental exposure to toxic levels of manganese causes a syndrome similar to PD and is thus an environmental risk factor for the disease. How manganese contributes to neurodegeneration is poorly understood. Here we describe multiple genome-wide screens in yeast aimed at defining the cellular function of Ypk9 and the mechanisms by which it protects cells from manganese toxicity. In physiological conditions, we found that Ypk9 genetically interacts with essential genes involved
  https://www.garvan.org.au/research/publications/11614
*  Manganese Mining Market Sales, Size, Share, Trends and Forecast 2021 | Business
Before It's News). Manganese Mining Market research report is a professional and in-depth study on the current state of the Manganese Mining Industry.. The Report provides a basic overview of the Manganese Mining Market including definitions, classifications, applications and chain structure. The Manganese Mining Industry analysis is provided for the international market including development history, competitive landscape analysis, and major regional development status.. Split by application, this report focuses on consumption, market share and growth rate of Manganese Mining in each application, can be divided into:. 1.Alloys. 2.Others (electrolytic manganese metals (EMM) and electrolytic manganese dioxides (EMD)). 3.Application 3. To begin with, the report elaborates Manganese Mining Market overview. Various definitions and classification of the industry, applications of industry and chain structure are given. Present day status of the Manganese Mining Market in key regions is stated and ...
  http://beforeitsnews.com/business/2016/10/manganese-mining-market-sales-size-share-trends-and-forecast-2021-3010457.html
*  Jefferson Elementary School - Gary, IN | Assessing Outdoor Air Near Schools | US EPA
Analysis of Measured Manganese Concentrations:. 1. Calculate the average: We calculated the average of the manganese measurements (shown by the black diamond in the graph below). We compared this average to the long-term comparison level (thick line on the graph below). The long-term comparison level represents the level of manganese in the air that is below levels associated with health concerns, even if someone breathed air containing manganese at that level all day, every day over their lifetime. Result: The average manganese level for the samples collected was slightly above the long-term comparison level. There is a potential for levels of health concern for long-term continuous exposure, particularly in areas closer to sources where concentrations are higher. ...
  https://www3.epa.gov/air/sat/JeffersonE.html
*  NewsRoomAmerica.com - Manganese in underground drinking water is cause for concern
Newsroom America) -- Underground drinking water sources in parts of the U.S. and three Asian countries may not be as safe as previously thought due to high levels of manganese, especially at shallow depths, according to a study led by a researcher at the University of California, Riverside. Manganese, a metal that is required by the body in tiny amounts, can be toxic at elevated levels, particularly in children.. Samantha Ying, an assistant professor of environmental sciences in UCR's College of Natural and Agricultural Sciences, led the study, which was published recently in Environmental Science & Technology. The paper describes manganese levels that exceed World Health Organization (WHO) guidelines in groundwater wells in Bangladesh, Cambodia, China, and the Glacial Aquifer, which spans 26 states in the northern U.S. and provides drinking water to more than 41 million Americans. Of the four regions, the Glacial Aquifer had the fewest contaminated wells.. While groundwater can be contaminated ...
  http://newsroomamerica.com/story/658943/manganese_in_underground_drinking_water_is_cause_for_concern.html
*  Is Manganese a Risk Factor for PD? | ALZFORUM
No one knows exactly what causes sporadic Parkinson's disease, but scientists know that both genetic and environmental risk factors contribute. One suspected environmental culprit is manganese, a metal often alloyed with steel to increase its hardness. High levels of manganese are known to be neurotoxic; data on the effects of low levels of environmental manganese exposure are limited, but suggest a link to parkinsonism or PD. A paper in the April 12 Neurology provides compelling new evidence that chronic exposure to manganese correlates with damage to the brain's dopaminergic system. Researchers led by Brad Racette at Washington University, St. Louis, Missouri, found that relatively young, healthy welders, whose work often subjects them to manganese-laden fumes, have abnormalities in dopamine uptake in the caudate nucleus, one of the regions of the brain affected in PD patients. They also had very subtle motor deficits. The long-term medical significance of this finding is unclear, but the data ...
  http://www.alzforum.org/news/research-news/manganese-risk-factor-pd
*  Contents - Plant Soil - GUWS Medical
12.1 Introduction 351. 12.2 Forms of Manganese and Abundance in Soils 352. 12.3 Importance to Plants and Animals 352. 12.3.1 Essentiality of Manganese to Higher Plants 352. 12.3.2 Function in Plants 352. 12.3.3 Importance to Animals 353. 12.4 Absorption and Mobility 353. 12.4.1 Absorption Mechanisms 353. 12.4.2 Distribution and Mobility of Manganese in Plants 353. 12.5 Manganese Deficiency 354. 12.5.1 Prevalence 354. 12.5.2 Indicator Plants 354. 12.5.3 Symptoms 354. 12.5.4 Tolerance 355. 12.6 Toxicity 356. 12.6.1 Prevalence 356. 12.6.2 Indicator Plants 356. 12.6.3 Symptoms 356. 12.6.4 Tolerance 357. 12.7 Manganese and Diseases 357. 12.8 Conclusion 365. Acknowledgments 365. References 366. ...
  https://www.guwsmedical.info/plant-soil/contents-oov.html
*  Oxygen Evolving Reactions by Synthetic Manganese Complexes
The development of efficient catalyst for water oxidation is of paramount importance to artificial photosynthesis, but before this can be achieved a deeper understanding of this reaction is essential. In nature this reaction occurs in a tetranuclear Mn-cluster which serves as the work-horse of oxygenic photosynthesis. This thesis summarises my efforts at developing molecular systems capable of mimicking this complex employing a biomimetic approach.. Three different approaches towards this goal are described here-in. The first section describes a screening study, in which a number of manganese complexes were tested to see whether or not they were capable of catalysing the formation of dioxygen when treated with different oxidants (Papers I). For those reactions in which dioxygen formation was observed the reactions were repeated in labelled water and the incorporation of labelled O-atoms was studied by mass spectrometry. This allowed us to determine to what extent water was the source of the ...
  http://uu.diva-portal.org/smash/record.jsf?pid=diva2:236134
*  Environmental Health Perspectives - Associations of Early Childhood Manganese and Lead Coexposure with Neurodevelopment
This study suggests that joint exposure to manganese and lead is associated with greater deficits in both mental and psychomotor development than expected based on effects of exposure to either metal alone. Interestingly, this interaction was observed for 12-month but not for 24-month blood metal concentrations. A possible interpretation of the specificity of the interaction of 12-month blood manganese-lead levels is that this is a sensitive developmental window specific to this interaction. From repeated measures models, for a one-unit increase in lead at 12 months, MDI scores were 2.16 points lower among children with high manganese (-0.89 + -0.07 + -1.27 = -2.23), compared with children with midrange manganese [-0.07 (95% CI: -0.39, 0.25)]. PDI scores for a one-unit increase in lead at 12 months were 0.97 points lower among children with high manganese (-0.05 + -0.27 + -0.92 = -1.24), compared with children with midrange manganese [-0.27 (95% CI: -0.56, 0.02)]. Although these differences ...
  https://ehp.niehs.nih.gov/1003300/
*  NIOSHTIC-2 Publications Search - 00036333 - The role of manganese in human disease.
The role of manganese (7439965) in the human body and its toxic effects as a neurotoxic metal are discussed, with emphasis on susceptibility to manganese poisoning from pollution caused by substitution of manganese for lead as an antiknock agent in gasoline. Similarity of manganese poisoning to parkinsonism is discussed, also treatment and response to levodopa. Manganese is determined to present a
  https://www.cdc.gov/niosh/nioshtic-2/00036333.html
*  Edta Manganese Sodium, Edta Manganese Sodium Suppliers and Manufacturers at Alibaba.com
Edta Manganese Sodium, Wholesale Various High Quality Edta Manganese Sodium Products from Global Edta Manganese Sodium Suppliers and Edta Manganese Sodium Factory,Importer,Exporter at Alibaba.com.
  http://www.alibaba.com/showroom/edta-manganese-sodium.html
*  Manganese Salt Price, China Manganese Salt Price Manufacturers & Suppliers | Made-in-China.com
Manganese Salt Price - Select 2017 high quality Manganese Salt Price products in best price from certified Chinese Manganese Powder manufacturers, Edta Manganese Salt suppliers, wholesalers and factory on Made-in-China.com
  http://www.made-in-china.com/products-search/hot-china-products/Manganese_Salt_Price.html
*  China Manganese Sulphate Monohydrate - China Manganese Sulphate, Mnso4
China Manganese Sulphate Monohydrate, Find details about China Manganese Sulphate, Mnso4 from Manganese Sulphate Monohydrate - Changsha Green Mountain Chemical Co., Ltd.
  http://changshamayshine.en.made-in-china.com/product/KbtxdWaOfcVk/China-Manganese-Sulphate-Monohydrate.html
*  Golgi Manganese Transport Is Required for Rapamycin Signaling in Saccharomyces cerevisiae | Genetics
PMR1 is a member of the P-type ATPase family of ion transporters (Rudolph et al. 1989; Antebi and Fink 1992). P-type ATPases bind ATP and are phosphorylated at a step in their transport cycles (Vanoevelen et al. 2005). Pmr1 transports Ca2+ or Mn2+ ions with high affinity from the cytoplasmic space into compartments of the secretory pathway (Rudolph et al. 1989). Pmr1 helps maintain cytoplasmic Ca2+ concentration at low values that inhibit signaling to Ca2+ effectors until a stimulus, often a cellular stress, induces a transient rise in cytoplasmic Ca2+ (Cyert 2003; Mulet et al. 2006). A pmr1 mutant increases cytosolic Ca2+ and increases Ca2+ entry and accumulation in the vacuole. Pmr1 also provides compartments of the secretory pathway lumenally with Ca2+ and Mn2+. There are possible roles for both ions within the Golgi, including roles in protein modification, in regulation of sorting and vesicular traffic, and in removal of toxic levels of ions. Mannosyltransferases present in the Golgi ...
  http://www.genetics.org/content/177/1/231
*  China Manganese Sulphate Monohydrate Powder Mn 32% - China Manganese Sulphate Monohydrate, Mn 32%
China Manganese Sulphate Monohydrate Powder Mn 32%, Find details about China Manganese Sulphate Monohydrate, Mn 32% from Manganese Sulphate Monohydrate Powder Mn 32% - Zouping Runzi Chemical Industry Co., Ltd.
  http://runzichem.en.made-in-china.com/product/EvdmenqMaGUI/China-Manganese-Sulphate-Monohydrate-Powder-Mn-32-.html
*  Manganese (VII) solution - Stock Image A710/0111 - Science Photo Library
Manganese solution. Flask containing a solution of manganese (VII) (MnO4[-]) solution. Manganese is a transition metal. Different oxidation states of manganese produce different coloured solutions. For a range of oxidation states see A710/108 - A710/111. - Stock Image A710/0111
  http://www.sciencephoto.com/media/9786/view