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*  Biotage - Search Literature
Reversed-phase chromatography facilitates the isolation of milligram to multi-gram quantities of polar compounds from naturally ... Real-time Fraction Purity Analysis in Reversed-phase Flash Chromatography Part No: AN062 Issued year: 2012 File size: 1.44mb ... Reversed-phase purification is a modification of normalphase chromatography that provides an efficient mechanism for the ... Reversed Phase Purification of Natural Products Part No: AN065 Issued year: 2012 File size: 0.99mb File type: pdf ...
  http://www.biotage.com/literature/search/10/100?search_query=
*  Reversed-phase chromatography - Wikipedia
"Reverse-phase chromatography of polar biological substances: separation of catechol compounds by high-performance liquid ... hence the term reversed-phase chromatography. Reversed-phase chromatography employs a polar (aqueous) mobile phase. As a result ... Reversed-phase chromatography (also called RPC, reverse-phase chromatography, or hydrophobic chromatography) includes any ... "reversed-phase chromatography". Akul Mehta (December 27, 2012). "Principle of Reversed-Phase Chromatography HPLC/UPLC (with ...
  https://en.wikipedia.org/wiki/Reversed-phase_chromatography
*  Biotage - Search Literature
Reversed-phase chromatography is typically used when you need to separate several milligrams of relatively polar compounds that ... When it comes to polar organic compound purification, many chemists turn to normal-phase flash chromatography often utilizing ... If you are currently using reversed-phase at preparative scale, such as flash chromatography, you know the mobile phase ... Greener reversed-phase Flash Chromatography Using Acetone Instead of Acetonitrile Part No: P158 Issued year: 2017 File size: ...
  http://www.biotage.com/literature/search?q=&display_type=1&document_search%5Bproduct_page_ids%5D%5B%5D=200
*  Biotage - Biotage® SNAP Ultra C18
SNAP Ultra C18 are reversed phase cartridges that can load 2-3% sample and enables really fast, cost effecient and sharp peak ... Reversed-phase chromatography facilitates the isolation of milligram to multi-gram quantities of polar compounds from naturally ... "We would not have been able to separate these two compounds using the old Biotage reverse phase C18 silica columns." Dr Gianna ... Reversed Phase: Highly Effective for Polar Molecule Purifications. Unlike normal-phase chromatography, reversed-phase uses a ...
  https://biotage.com/product-page/biotage-snap-ultra-c18
*  Biotage - Search Literature
Reversed-phase chromatography is typically used when you need to separate several milligrams of relatively polar compounds that ... type of polymeric reverse phase adsorbent that is able to provide improved separations of a range of small chemical compounds ... If you are currently using reversed-phase at preparative scale, such as flash chromatography, you know the mobile phase ... Greener reversed-phase Flash Chromatography Using Acetone Instead of Acetonitrile Part No: P158 Issued year: 2017 File size: ...
  http://www.biotage.com/literature/search/15/50?search_query=
*  Biotage - Search Literature
Reversed-phase chromatography is typically used when you need to separate several milligrams of relatively polar compounds that ... type of polymeric reverse phase adsorbent that is able to provide improved separations of a range of small chemical compounds ... If you are currently using reversed-phase at preparative scale, such as flash chromatography, you know the mobile phase ... Impact of Injection Solvent Choice on Peak Shape and Resolution in Reversed-phase Flash Chromatography Part No: P140 Issued ...
  http://www.biotage.com/literature/search/8/100?search_query=
*  Biotage - Isolera™ Dalton
Reversed-phase chromatography is typically used when you need to separate several milligrams of relatively polar compounds that ... and is capable of handling both normal and reverse-phase samples with ease. ... Greener reversed-phase Flash Chromatography Using Acetone Instead of Acetonitrile As reversed-phase flash chromatography gains ... Acetonitrile as a Replacement for Methanol in Normal-phase Flash Chromatography When it comes to polar organic compound ...
  http://biotage.com/product-page/isolera-dalton
*  Thin-layer chromatography - Wikipedia
... when the stationary phase is polar and the mobile phase is non-polar, the method is normal-phase as opposed to reverse-phase. ... If a reversed order of running of the compounds is desired, an apolar stationary phase should be used, such as C18- ... For instance, if normal-phase silica gel is used as the stationary phase, it can be considered polar. Given two compounds that ... For example, with silica gel, a very polar substance, non-polar mobile phases such as heptane are used. The mobile phase may be ...
  https://en.wikipedia.org/wiki/Thin-layer_chromatography
*  Chromatography - Wikipedia
... is polar (e.g. paper, silica etc.) it is forward phase chromatography, and if it is non-polar (C-18) it is reverse phase. ... Reversed-phase chromatography (RPC) is any liquid chromatography procedure in which the mobile phase is significantly more ... Ion exchange chromatography uses a charged stationary phase to separate charged compounds including anions, cations, amino ... such as hexane in normal phase or a polar solvent such as methanol in reverse phase chromatography and the sample being ...
  https://en.wikipedia.org/wiki/Chromatography
*  Micellar liquid chromatography - Wikipedia
Reverse phase high-performance liquid chromatography (RP-HPLC) involves a non-polar stationary phase, often a hydrocarbon chain ... Micellar liquid chromatography (MLC) is a form of reversed phase liquid chromatography that uses an aqueous micellar solutions ... and somewhat on the polar groups present in the stationary phase. 23 compounds were analyzed with varying mobile phases and ... "Chromatographic behaviour in reversed-phase high-performance liquid chromatography with micellar and submicellar mobile phases ...
  https://en.wikipedia.org/wiki/Micellar_liquid_chromatography
*  Liquid chromatography-mass spectrometry - Wikipedia
... stationary phase and a polar mobile phase. In common applications, the mobile phase is a mixture of water and other polar ... size-exclusion chromatography, and affinity chromatography. Among these, the most widely used variant is the reverse-phase (RP ... TSP was also more suitable for LC-MS applications involving reversed phase liquid chromatography (RT-LC). The TSP system had a ... "Analysis of Highly Polar Compounds of Plant Origin: Combination of Hydrophilic Interaction Chromatography and Electrospray Ion ...
  https://en.wikipedia.org/wiki/Liquid_chromatography%E2%80%93mass_spectrometry
*  Partition coefficient - Wikipedia
Brodsky J, Ballschmiter K (1988). "Reversed phase liquid chromatography of PCBs as a basis for calculation of water solubility ... This ratio is therefore a measure of the difference in solubility of the compound in these two phases. The partition- ... A number of methods of measuring distribution coefficients have been developed, including the shake-flask, reverse phase HPLC, ... the non-polar phase in such experiments is usually dominated by the un-ionized form of the solute, which is electrically ...
  https://en.wikipedia.org/wiki/Partition_coefficient
*  Diels-Alder reaction - Wikipedia
... to form various N-heterocyclic compounds via the aza-Diels-Alder reaction. Nitroso compounds (R-N=O) can react with dienes to ... Regardless of which situation pertains, the HOMO and LUMO of the components are in phase and a bonding interaction results as ... There is a notable rate enhancement when certain Diels-Alder reactions are carried out in polar organic solvents such as ... Diels-Alder reactions can be reversible under certain conditions; the reverse reaction is known as the retro-Diels-Alder ...
  https://en.wikipedia.org/wiki/Diels%E2%80%93Alder_reaction
*  Drug discovery - Wikipedia
Chemical compounds exist in nature as mixtures, so the combination of liquid chromatography and mass spectrometry (LC-MS) is ... The drug requires very expensive Phase I, II and III clinical trials, and most of them fail. Small companies have a critical ... This approach is known as reverse pharmacology and is the most frequently used approach today. The definition of "target" ... Revisiting natural products with modern chemistry and target-finding tools from biology (reversed genomics) is one option for ...
  https://en.wikipedia.org/wiki/Drug_discovery
*  Modafinil - Wikipedia
"Determination of modafinil in plasma and urine by reversed phase high-performance liquid-chromatography". Journal of ... Modafinil is the primary metabolite of adrafinil, lacking the polar -OH group on its terminal amide, and has similar activity ... U.S. Patent 4,927,855 was issued to Laboratoire L. Lafon on May 22, 1990, covering the chemical compound modafinil. After ... In addition, modafinil fails to reverse reserpine-induced akinesia, whereas dextroamphetamine, a dopamine releasing agent (DRA ...
  https://en.wikipedia.org/wiki/Modafinil
*  Nitrogen - Wikipedia
... nitro compounds (RNO2), nitroso compounds (RNO), oximes (RCR=NOH), and pyridine derivatives. C-N bonds are strongly polarised ... Many stoichiometric phases are usually present for most elements (e.g. MnN, Mn6N5, Mn3N2, Mn2N, Mn4N, and MnxN for 9.2 < x < ... It is very weak and flows in the form of glaciers and on Triton geysers of nitrogen gas come from the polar ice cap region. The ... Journal of Chromatography A. 943 (2): 295-97. doi:10.1016/S0021-9673(01)01466-2. PMID 11833649. Baxter, E. Denise; Hughes, Paul ...
  https://en.wikipedia.org/wiki/Nitrogen