Racivir | CAS#143491-54-7 | transcriptase inhibitor | MedKoo
... is a reverse transcriptase inhibitor potentially for the treatment of HIV infection. 524W91 was anabolized to the active 5'- ... New nucleoside reverse transcriptase inhibitors for the treatment of HIV infections. Curr Opin Pharmacol. 2004 Oct;4(5):431-6. ... Mechanistic studies show that (-)-FTC-TP is a better inhibitor of HIV-1 reverse transcriptase than 3TC-TP. FASEB J. 1999 Sep;13 ... Description: Racivir, also known as PSI-5004; (±)-FTC; RCV, 524W91, is a reverse transcriptase inhibitor potentially for the ...http://www.medkoo.com/products/11568
Reverse Transcriptase Inhibitors | Portsmouth Regional Hospital
Learn more about Reverse Transcriptase Inhibitors at Portsmouth Regional Hospital Coenzyme Q 10 - Possible Benefits and Risks ... There are two major categories of reverse transcriptase inhibitors: nucleoside/nucleotide reverse transcriptase inhibitors ( ... non-nucleoside reverse transcriptase inhibitors (NNRTIs) . Reverse transcriptase inhibitors include: *Combivir (lamivudine and ... It does so by using an enzyme called reverse transcriptase. Reverse transcriptase inhibitors interfere with this process. ...http://portsmouthhospital.com/hl/?/111797/Hivid&com.dotmarketing.htmlpage.language=1
Non-nucleoside reverse transcriptase inhibitors failure impairs HIV-RNA responses to efavirenz-containing salvage...
A lack of the previous use of non-nucleoside reverse transcriptase inhibitors was the only factor predictive of response on ... A lack of the previous use of non-nucleoside reverse transcriptase inhibitors was the only factor predictive of response on ... Non-nucleoside reverse transcriptase inhibitors failure impairs HIV-RNA responses to efavirenz-containing salvage ...http://www.cfenet.ubc.ca/publications/non-nucleoside-reverse-transcriptase-inhibitors-failure-impairs-hiv-rna-responses
Effects of Two Anti-HIV Drug Combinations on the Immune Systems of HIV-Infected Patients Who Have Never Received Anti-HIV Drugs...
HIV Protease Inhibitors. Lamivudine. Nevirapine. Abacavir. Stavudine. Protease Inhibitors. Reverse Transcriptase Inhibitors. ... Nucleoside Analogue Reverse Transcriptase Inhibitors d4T/3TC/Abacavir With the Non-Nucleoside Reverse Transcriptase Inhibitor ... HIV Protease Inhibitors. Ritonavir. Lamivudine. Reverse Transcriptase Inhibitors. Anti-HIV Agents. ABT 378. abacavir. ... This study will compare an anti-HIV drug combination of protease inhibitor plus a nonnucleoside reverse transcriptase inhibitor ...https://clinicaltrials.gov/show/NCT00004855?order=213
The M230L Nonnucleoside Reverse Transcriptase Inhibitor Resistance Mutation in HIV-1 Reverse Transcriptase Impairs Enzymatic...
The M230L Nonnucleoside Reverse Transcriptase Inhibitor Resistance Mutation in HIV-1 Reverse Transcriptase Impairs Enzymatic ... Reverse transcriptase mutations that confer nonnucleoside reverse transcriptase inhibitor resistance may also impair ... The HIV-1 reverse transcriptase mutants G190S and G190A, which confer resistance to non-nucleoside reverse transcriptase ... Leu-188 in the reverse transcriptase of HIV-2 and SIV renders them sensitive to non-nucleoside reverse transcriptase inhibitors ...http://pubmedcentralcanada.ca/pmcc/articles/PMC2876396/
Dose Ranging Study of GSK1265744 Plus Nucleoside Reverse Transcriptase Inhibitors for Induction of Human Immunodeficiency Virus...
Reverse Transcriptase Inhibitors. Antiviral Agents. Anti-Infective Agents. Nucleic Acid Synthesis Inhibitors. Enzyme Inhibitors ... The background dual nucleoside reverse transcriptase inhibitor (NRTI) antiretroviral therapy (ART) for all arms will be either ... A Phase IIb, Dose Ranging Study of Oral GSK1265744 in Combination With Nucleoside Reverse Transcriptase Inhibitors for ... Dose Ranging Study of GSK1265744 Plus Nucleoside Reverse Transcriptase Inhibitors for Induction of Human Immunodeficiency Virus ...https://clinicaltrials.gov/show/NCT01641809?order=9
Observation of HIV-Infected Children Receiving Protease Inhibitor and Reverse Transcriptase Inhibitor - Full Text View -...
Protease Inhibitors. HIV Protease Inhibitors. Reverse Transcriptase Inhibitors. Enzyme Inhibitors. Molecular Mechanisms of ... Observation of HIV-Infected Children Receiving Protease Inhibitor and Reverse Transcriptase Inhibitor. The safety and ... Currently on at least a three drug combination that includes a protease inhibitor (PI) and reverse transcriptase inhibitor (RTI ... or their medicines will be changed to a different combination of protease inhibitor and reverse transcriptase inhibitor. Before ...https://clinicaltrials.gov/show/NCT00001826?order=247
Evaluation of HIV protease and nucleoside reverse transcriptase inhibitors on proliferation, necrosis, apoptosis in intestinal...
... in contrast to the reverse transcriptase inhibitors which did not have such an effect. Additionally, both PI's and reverse ... The nucleoside reverse transcriptase inhibitors, AZT and DDI, did not affect cell apoptosis or proliferation. These findings ... Protease inhibitors (PI's) and reverse transcriptase drugs are important components of highly active antiretroviral therapy ( ... Protease inhibitors (PI's) and reverse transcriptase drugs (RTs) are important components of highly active antiretroviral ...https://bmcgastroenterol.biomedcentral.com/articles/10.1186/1471-230X-10-90
Reverse transcriptase inhibitor legal definition of reverse transcriptase inhibitor
What is reverse transcriptase inhibitor? Meaning of reverse transcriptase inhibitor as a legal term. What does reverse ... Definition of reverse transcriptase inhibitor in the Legal Dictionary - by Free online English dictionary and encyclopedia. ... Reverse transcriptase inhibitor legal definition of reverse transcriptase inhibitor https://legal-dictionary.thefreedictionary. ... inhibitor. (redirected from reverse transcriptase inhibitor). Also found in: Dictionary, Thesaurus, Medical, Acronyms, ...https://legal-dictionary.thefreedictionary.com/reverse+transcriptase+inhibitor
Provider bias in the selection of non-nucleoside reverse transcriptase inhibitor and protease inhibitor-based highly active...
... and protease inhibitors (PI), and evaluate treatment outcomes in a setting in which nevirapine has been preferentially ... To compare the characteristics of patients prescribed non-nucleoside reverse transcriptase inhibitors (NNRTI) ... Provider bias in the selection of non-nucleoside reverse transcriptase inhibitor and protease inhibitor-based highly active ... OBJECTIVE: To compare the characteristics of patients prescribed non-nucleoside reverse transcriptase inhibitors (NNRTI) and ...http://www.cfenet.ubc.ca/node/4671
Effects of Two Anti-HIV Drug Combinations on the Immune Systems of HIV-Infected Patients Who Have Never Received Anti-HIV Drugs...
Nucleoside Analogue Reverse Transcriptase Inhibitors d4T/3TC/Abacavir With the Non-Nucleoside Reverse Transcriptase Inhibitor ... This study will compare an anti-HIV drug combination of protease inhibitor plus a nonnucleoside reverse transcriptase inhibitor ... Arm B (triple reverse transcriptase inhibitors plus NNRTI regimen): At Day 0 (entry), patients begin taking 3TC plus d4T plus ... It will ascertain if treatment regimens containing nucleoside reverse transcriptase inhibitors (NRTIs) with a nonnucleoside ...https://clinicaltrials.gov/ct2/show/record/NCT00004855
Nucleoside reverse transcriptase inhibitor legal definition of nucleoside reverse transcriptase inhibitor
What is nucleoside reverse transcriptase inhibitor? Meaning of nucleoside reverse transcriptase inhibitor as a legal term. What ... does nucleoside reverse transcriptase inhibitor mean in law? ... Definition of nucleoside reverse transcriptase inhibitor in the ... protease inhibitors, non- nucleoside reverse transcriptase inhibitors, nucleoside/nucleotide reverse transcriptase inhibitors) ... Nucleoside reverse transcriptase inhibitor legal definition of nucleoside reverse transcriptase inhibitor https://legal- ...http://legal-dictionary.thefreedictionary.com/nucleoside+reverse+transcriptase+inhibitor
"Nucleoside reverse-transcriptase inhibitor dosing errors in an outpati" by James H. Willig, Andrew O. Westfall et al.
We evaluated factors associated with nucleoside reverse-transcriptase inhibitor dosing errors in a university-based HIV clinic ... Understanding the factors related to nucleoside reverse-transcriptase inhibitor dosing errors is an important step in the ... contributed to the higher rates of errors in nucleoside reverse-transcriptase inhibitor dosing. ... Nucleoside reverse-transcriptase inhibitor dosing errors in an outpatient HIV clinic in the electronic medical record era ...http://escholarship.umassmed.edu/qhs_pp/818/
Antiviral Responses to NNRTI-Based vs. PI-Based ARV Therapy in HIV Infected Infants Who Have or Have Not Received Single Dose...
Non-nucleoside reverse transcriptase inhibitor (NNRTI)-based regimens are recommended for use by the World Health Organization ... The purpose of this study was to compare the effectiveness of a non-nucleoside reverse transcriptase inhibitor (NNRTI)-based ... The purpose of this trial was to compare and evaluate virologic responses to an NNRTI-based regimen versus a protease-inhibitor ... antiretroviral regimen versus a protease inhibitor (PI)-based regimen in HIV infected infants who had or had not been exposed ...https://clinicaltrials.gov/ct2/show/record/NCT00307151?view=results
Maraviroc and reverse transcriptase inhibitors combinations as potential preexposure prophylaxis candidates - GOV.UK
... and reverse transcriptase inhibitors (RTIs). Design: The entry inhibitor, MVC, a nucleotide RTI, tenofovir and two non- ... Maraviroc and reverse transcriptase inhibitors combinations as potential preexposure prophylaxis candidates. AIDS (2016) 30 (7 ... This study demonstrates that combinations based on antiretroviral drugs inhibiting HIV transmission at viral entry and reverse ...https://www.gov.uk/dfid-research-outputs/maraviroc-and-reverse-transcriptase-inhibitors-combinations-as-potential-preexposure-prophylaxis-candidates
Reverse Transcriptase Inhibitors
Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence ...http://hivdb.stanford.edu/cgi-bin/GetIsolateDataResiSubtype.cgi?class=NNRTI&subtype=F&pos=179&cons=V&aa=E&rx=NNRTI&includeMixtures=No
Reverse-transcriptase inhibitor - Wikipedia
Nucleotide analog reverse-transcriptase inhibitors (NtARTIs or NtRTIs) Non-nucleoside reverse-transcriptase inhibitors (NNRTIs ... NNRTIs are therefore classified as non-competitive inhibitors of reverse transcriptase. Nucleoside analog reverse-transcriptase ... Discovery and development of non-nucleoside reverse-transcriptase inhibitors Protease inhibitors Discovery and development of ... Reverse-transcriptase inhibitors (RTIs) are a class of antiretroviral drugs used to treat HIV infection or AIDS, and in some ...https://en.wikipedia.org/wiki/Reverse-transcriptase_inhibitor
Discovery and development of non-nucleoside reverse-transcriptase inhibitors - Wikipedia
... nucleoside/nucleotide reverse-transcriptase inhibitors (NRTIs/NtRTIs) and non-nucleoside reverse-transcriptase inhibitors ( ... Antiretroviral drug Reverse-transcriptase inhibitor Protease inhibitor Entry inhibitor Discovery and development of HIV- ... Non-nucleoside reverse-transcriptase inhibitors (NNRTIs) are antiretroviral drugs used in the treatment of human ... Jochmans D (June 2008). "Novel HIV-1 reverse transcriptase inhibitors". Virus Research. 134 (1-2): 171-85. doi:10.1016/j. ...https://en.wikipedia.org/wiki/Discovery_and_development_of_non-nucleoside_reverse-transcriptase_inhibitors
Discovery and development of nucleoside and nucleotide reverse-transcriptase inhibitors - Wikipedia
Reverse-Transcriptase Inhibitors Discovery and Development of HIV Protease Inhibitors Reverse-transcriptase inhibitor Protease ... protease inhibitors, entry inhibitors, co-receptor inhibitors and integrase inhibitors. The reverse transcriptase of HIV-1 has ... Nucleoside and nucleotide reverse-transcriptase inhibitors, Non-nucleoside reverse-transcriptase inhibitors, ... non-nucleoside reverse-transcriptase inhibitors and protease inhibitors. Currently, there are several NRTIs in various stages ...https://en.wikipedia.org/wiki/Discovery_and_development_of_nucleoside_and_nucleotide_reverse-transcriptase_inhibitors
Acute fatty liver of pregnancy - Wikipedia
Montessori V, Harris M, Montaner JS (2003). "Hepatotoxicity of nucleoside reverse transcriptase inhibitors". Semin. Liver Dis. ... including nucleoside reverse transcriptase inhibitors used to treat HIV, and a rare condition known as Jamaican vomiting ...https://en.wikipedia.org/wiki/Acute_fatty_liver_of_pregnancy
Zidovudine - Wikipedia
... such as a protease inhibitor, non-nucleoside reverse transcriptase inhibitor, or integrase inhibitor; this type of therapy is ... ZDV is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. It works by inhibiting the enzyme reverse ... Their research efforts were focused in part on the viral enzyme reverse transcriptase. Reverse transcriptase is an enzyme that ... Quan, Y; Rong, L; Liang, C; Wainberg, MA (1999). "Reverse Transcriptase Inhibitors Can Selectively Block the Synthesis of ...https://en.wikipedia.org/wiki/Zidovudine
Didanosine - Wikipedia
It is of the reverse transcriptase inhibitor class. Didanosine was first described in 1975 and approved for use in the United ... Like other anti-HIV nucleoside analogs, it acts as a chain terminator by incorporation and inhibits viral reverse transcriptase ...https://en.wikipedia.org/wiki/Didanosine
Emivirine - Wikipedia
It is a non-nucleoside reverse transcriptase inhibitor. While emivirine showed promising antiviral activity in vitro, it failed ...https://en.wikipedia.org/wiki/Emivirine
Abacavir/dolutegravir/lamivudine - Wikipedia
... reverse transcriptase inhibitor), 50 mg dolutegravir (integrase inhibitor) and 300 mg lamivudine (nucleoside analog reverse ... Abacavir is a nucleotide reverse transcriptase inhibitor. Specifically, abacavir is a guanosine analogue that interferes with ... transcriptase inhibitor). The drug was developed by ViiV Healthcare and approved by the Food and Drug Administration for use in ... Lamivudine is a cytosine analogue that inhibits HIV reverse transcription by terminating the viral DNA chain. Efficacy of ...https://en.wikipedia.org/wiki/Abacavir/dolutegravir/lamivudine
Abacavir - Wikipedia
"Nucleoside reverse transcriptase inhibitors (NRTIs or 'nukes') - HIV/AIDS". www.hiv.va.gov. Archived from the original on 2016- ... Abacavir is a nucleoside reverse transcriptase inhibitor that inhibits viral replication. It is a guanosine analogue that is ... Similar to other nucleoside reverse transcriptase inhibitors (NRTIs), abacavir is used together with other HIV medications, and ... a Potent Inhibitor of HIV Reverse Transcriptase". The Journal of Organic Chemistry. 61 (13): 4192-4193. doi:10.1021/jo960708p. ...https://en.wikipedia.org/wiki/Abacavir