*  ANATOMY OF PHOTORECEPTORS
elial cells turned upside down with their tips immersed in the pigmented layer of the retina. Going from the pigmented layer ... Rods and cones are attached differently to other retinal neurons causing further differences in their abilities. Rods are in ... The rods and each of the three cone types contain unique visual pigments, that absorb different wavelengths of light and have ... The light absorbing visual pigments are packaged in membrane bound discs within the outer segments. The coupling of the ...
  http://www.chm.bris.ac.uk/webprojects2003/white/functional_anatomy_of.htm
*  Gene Duplication and Spectral Diversification of Cone Visual Pigments of Zebrafish | Genetics
... cis retinal in the pigments was isomerized by light and all-trans retinal was released. Insets of Figure 6 show the dark-light ... The chromophore of the visual pigments of zebrafish is predominantly 11-cis retinal and not the 11-cis 3,4-dehydroretinal that ... 1995 The visual pigment of fish. Prog. Retinal Eye Res. 15: 1-31. ... It should be noted that the λmax of SWS2 pigment (416 nm) is relatively short compared to those of many other SWS2 pigments ...
  http://www.genetics.org/content/163/2/663
*  Variation in Macular Pigment Density: Genetics and Nutrition
... reduced risk of AMD with higher serum levels of the retinal carotenoids lutein and zeaxanthin; and 3) reduced risk of AMD with ... Variation in Macular Pigment Density: Genetics and Nutrition. In an earlier issue the relationship between macular pigment ... In a study by Hammond and colleagues (1), results indicated a higher macular pigment density among males compared with females ... There is evidence that increasing macular pigment MP density may help prevent AMD. There is wide inter-patient variation in ...
  http://www.sciencebasedhealth.com/Variation-in-Macular-Pigment-Density-Genetics-and-Nutrition-W17.aspx
*  Photopigment optical densities
Bowmaker, J.K. & Dartnall, H.J.A. (1980). Visual pigments of rods and cones in a human retina. Journal of Physiology, London, ... Enoch, J.M. & Stiles, W.W. (1961). The colour change of monochromatic light with retinal angle of incidence. Optica Acta 8, 329 ... Dobelle, W.H., Marks, W.B. & MacNichol, E.F. (1969). Visual pigment densities in single primate foveal cones. Science 166, 1508 ... Miller, S.S. (1972). Psychophysical estimates of visual pigment densities in red-green dichromats. Journal of Physiology, ...
  http://www.cvrl.org/database/text/optdens/optdens.htm
*  Merbs & Nathans photopigment spectra
λmax values for normal and hybrid red-green pigments. Estimates of the peaks of the absorption spectra of the pigments ... The gene products -- the artificial opsins -- were then combined with 11-cis-retinal and the cell membranes were solubilized in ... indicate that the spectral sensitivity of each hybrid pigment is intermediate between the parental green and red pigment ... Merbs, S. L. & Nathans, J. (1992a). Absorption spectra of the hybrid pigments responsible for anomalous color vision. Science, ...
  http://www.cvrl.org/database/text/pigments/merbnath.htm
*  A Potential Role for All-Trans Retinal in Regulation of Metarhodopsin Decay in Human Rods | IOVS | ARVO Journals
In order to examine the relatives roles of CHM and CLM on the overall dynamics of pigment regeneration in human rods, we ... Purpose: : We sought to develop a model that could better account for the full dynamics of human rod pigment regeneration ... A. Navid, R.D. Hamer; A Potential Role for All-Trans Retinal in Regulation of Metarhodopsin Decay in Human Rods . Invest. ... A Potential Role for All-Trans Retinal in Regulation of Metarhodopsin Decay in Human Rods ...
  http://iovs.arvojournals.org/article.aspx?articleid=2391895
*  Retinal Pigmented Epithelial Cells Page 1
Retinal Pigmented Epithelial Cells * hTERT RPE-1 (ATCC® CRL-4000™) ATCC® Number: CRL-4000™ Organism: Homo sapiens, human ...
  https://www.atcc.org/Products/Cells_and_Microorganisms/hTERT_Immortalized_Cell_Lines/Retinal_Pigmented_Epithelial_Cells.aspx?geo_country=us
*  Retinal pigment epithelium detach... preview & related info | Mendeley
Purpose: To report the unusual association of vitreomacular traction syndrome (VMT) with retinal pigment epithelium (RPE) ... Conclusion: Retinal pigment epithelium detachment could be associated with VMT. Although the incidence is rare, it may ... Retinal pigment epithelium detachment associated with vitreomacular traction syndrome - Case report. *Georgalas I ... Purpose: To report the unusual association of vitreomacular traction syndrome (VMT) with retinal pigment epithelium (RPE) ...
  https://www.mendeley.com/research-papers/retinal-pigment-epithelium-detachment-associated-vitreomacular-traction-syndrome-case-report/
*  Advanced Cell Technology Awarded Broad Patent for Production of Retinal Pigment Epithelial Cells - PR.com
Advanced Cell Technology Awarded Broad Patent for Production of Retinal Pigment Epithelial Cells. This broad patent gives ... which is broadly directed to processes developed by ACT scientists for the production of retinal pigment epithelial (RPE) cells ... Our RPE technology is safe, scalable and has tremendous potential for treating many of the 200-plus retinal diseases. This ...
  https://www.pr.com/press-release/242563
*  Pump-probe detection of laser-induced microbubble formation in retinal pigment epithelium cells
Jan Roegener, Ralf Brinkmann, Charles P. Lin, "Pump-probe detection of laser-induced microbubble formation in retinal pigment ... Jan Roegener, Ralf Brinkmann, Charles P. Lin, "Pump-probe detection of laser-induced microbubble formation in retinal pigment ... Pump-probe detection of laser-induced microbubble formation in retinal pigment epithelium cells. ... are currently being investigated in a new ophthalmic procedure for treatment of disorders associated with the retinal pigment ...
  https://www.spiedigitallibrary.org/journals/Journal-of-Biomedical-Optics/volume-9/issue-2/0000/Pump-probe-detection-of-laser-induced-microbubble-formation-in-retinal/10.1117/1.1646413.short
*  Antioxidants | Free Full-Text | Effects of the Macular Carotenoid Lutein in Human Retinal Pigment Epithelial Cells
These findings contribute to the understanding of the protective mechanisms attributable to retinal xanthophylls in eye health ... in order to determine if there is effect specificity for macular pigment carotenoids. Using human RPE-derived ARPE-19 cells as ... cells are central to retinal health and homoeostasis. Oxidative stress-induced damage to the RPE occurs as part of the ... retinal pigment epithelium; hypoxia; oxidative stress; tBHP xanthophyll; lutein; lycopene; carotenoids; retinal pigment ...
  http://www.mdpi.com/2076-3921/6/4/100
*  Altered mTOR Signaling in Senescent Retinal Pigment Epithelium | IOVS | ARVO Journals
Altered mTOR Signaling in Senescent Retinal Pigment Epithelium You will receive an email whenever this article is corrected, ... Y. Chen, J. Cai, P. Sternberg, Jr.; Altered mTOR Signaling in Senescent Retinal Pigment Epithelium. Invest. Ophthalmol. Vis. ... The purposes of this study were to characterize the changes in mTOR pathway in senescent human retinal pigmental epithelium ( ...
  https://iovs.arvojournals.org/article.aspx?articleid=2374775
*  Isolation and biochemical characterization of frog retinal pigment epithelium cells. | IOVS | ARVO Journals
A New Method to Visualize the Intact Subretina From Retinal Pigment Epithelium to Retinal Tissue in Whole Mount of Pigmented ... Localization of cellular retinal-binding protein in bovine retina and retinal pigment epithelium, with a consideration of the ... Isolation and biochemical characterization of frog retinal pigment epithelium cells. You will receive an email whenever this ... R Salceda; Isolation and biochemical characterization of frog retinal pigment epithelium cells.. Invest. Ophthalmol. Vis. Sci. ...
  https://iovs.arvojournals.org/article.aspx?articleid=2177653
*  Cellular effects of lysosomal dysfunction in retinal pigment epithelial cells | IOVS | ARVO Journals
Cellular effects of lysosomal dysfunction in retinal pigment epithelial cells Mallika Valapala; Abdulla Alamri; Rhonda Grebe; J ... Purpose : The retinal pigment epithelial (RPE) is not only one of the most active phagocytic cell types in the body but also ... Cellular effects of lysosomal dysfunction in retinal pigment epithelial cells You will receive an email whenever this article ... Cellular effects of lysosomal dysfunction in retinal pigment epithelial cells. Invest. Ophthalmol. Vis. Sci. 2016;57(12):6048. ...
  https://iovs.arvojournals.org/article.aspx?articleid=2563975
*  Retinal pigmented epithelium determination requires the redundant activities of Pax2 and Pax6 | Development
... retinal, pigmented-epithelial and optic-stalk progenitor domains, suggesting redundant functions during retinal determination. ... Bumsted, K. M. and Barnstable, C. J. (2000). Dorsal retinal pigment epithelium differentiates as neural retina in the ... le, lens; nr, neural retina; os, optic stalk; ov, optic vesicle; rpe, retinal pigmented epithelium; se, surface ectoderm. ... Retinal pigmented epithelium determination requires the redundant activities of Pax2 and Pax6 ...
  http://dev.biologists.org/content/130/13/2903
*  Bone morphogenetic proteins specify the retinal pigment epithelium in the chick embryo | Development
Bone morphogenetic proteins specify the retinal pigment epithelium in the chick embryo ... Bone morphogenetic proteins specify the retinal pigment epithelium in the chick embryo ... Bone morphogenetic proteins specify the retinal pigment epithelium in the chick embryo ... Bone morphogenetic proteins specify the retinal pigment epithelium in the chick embryo ...
  http://dev.biologists.org/content/early/2007/08/29/dev.02884
*  Retinal pigment epithelial cells display specific transcriptional responses upon TNF-α stimulation
Tumour necrosis factor-α (TNF-α) is a key mediator of ocular inflammation and its interaction with the retinal pigment ... Retinal pigment epithelial cells display specific transcriptional responses upon TNF-α stimulation. ... Under inflammatory conditions, the ability of RPE cells to maintain the blood-retinal barrier and immune privilege may be lost ... into the unique responses of RPE cells to TNF-α stimulation and suggests a role for genes involved in apoptosis and retinal ...
  https://insights.ovid.com/bjop/201505000/00002388-201505000-00027
*  A regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development. | Sigma-Aldrich
A regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development.. [Kapil Bharti, ... The separation of the optic neuroepithelium into future retina and retinal pigment epithelium (RPE) is a critical event in ... results suggest that careful manipulation of the Pax6 regulatory circuit may facilitate the generation of retinal and pigment ... This role is seen, however, only in a background genetically sensitized by mutations in the pigment cell transcription factor ...
  https://www.sigmaaldrich.com/catalog/papers/22792072
*  Spatial Localization of A2E in the Retinal Pigment Epithelium | IOVS | ARVO Journals
A New Method to Visualize the Intact Subretina From Retinal Pigment Epithelium to Retinal Tissue in Whole Mount of Pigmented ... Lipofuscin and A2E in mouse retinal pigment epithelial tissues. Summary mass spectra from retinal pigment epithelial tissues of ... Lipofuscin and A2E in mouse retinal pigment epithelial tissues. Summary mass spectra from retinal pigment epithelial tissues of ... Lipofuscin and A2E in mouse retinal pigment epithelial tissues. Summary mass spectra from retinal pigment epithelial tissues of ...
  http://iovs.arvojournals.org/article.aspx?articleid=2187017
*  Cellular Effects of Corticosteroids on the Retinal Pigment Epithelium | IOVS | ARVO Journals
Cellular Effects of Corticosteroids on the Retinal Pigment Epithelium You will receive an email whenever this article is ... CF Arndt, C Knauf, G Caputo, J-C Beauvillain, R Matran; Cellular Effects of Corticosteroids on the Retinal Pigment Epithelium ...
  http://iovs.arvojournals.org/article.aspx?articleid=2418251
*  Ultrastructural Changes and Expression of PCNA and RPE65 in Sodium Iodate-Induced Acute Retinal Pigment Epithelium Degeneration...
... results in the visual dysfunction and blindness of retinal degenerative diseases. Injection of sodium iodate (NaIO3) generates ... Alteration in retinal pigment epithelium (RPE) results in the visual dysfunction and blindness of retinal degenerative diseases ... Strauss O (2005) The retinal pigment epithelium in visual function. Physiol Rev 85:845-881CrossRefPubMedGoogle Scholar ... Kennedy CJ, Rakoczy PE, Constable IJ (1995) Lipofuscin of the retinal pigment epithelium: a review. Eye 9:763-771CrossRefPubMed ...
  https://link.springer.com/article/10.1007/s11064-018-2508-9
*  Lipofuscin Can Be Eliminated From Retinal Pigment Epithelium After Drug Treatment | IOVS | ARVO Journals
Lipofuscin Can Be Eliminated From Retinal Pigment Epithelium After Drug Treatment S. Julien; A. Biesemeier; P. Heiduschka; M. ... It is generally believed that the gradual accumulation of this pigment is the constant sign of ageing and that the retinal ... Lipofuscin Can Be Eliminated From Retinal Pigment Epithelium After Drug Treatment You will receive an email whenever this ... Lipofuscin Can Be Eliminated From Retinal Pigment Epithelium After Drug Treatment. Invest. Ophthalmol. Vis. Sci. 2010;51(13): ...
  https://iovs.arvojournals.org/article.aspx?articleid=2369143
*  Regulation of the Casein Kinase -2 in Retinal Pigment Epithelial Cells | IOVS | ARVO Journals
Retinal pigment epithelial cells (RPEs) are regarded as the main cell type responsible for vitreoretinal scars in PVR. Their ... Regulation of the Casein Kinase -2 in Retinal Pigment Epithelial Cells You will receive an email whenever this article is ... S. Hoffmann, H. S. Walter, B. Seitz, M. Montenarh; Regulation of the Casein Kinase -2 in Retinal Pigment Epithelial Cells. ... Keywords: retinal pigment epithelium • growth factors/growth factor receptors • signal transduction: pharmacology/physiology ...
  https://iovs.arvojournals.org/article.aspx?articleid=2369150