Genome-wide evidence for selection acting on single amino acid repeats. - Physiology, Anatomy and Genetics
... there is increasing evidence for a functional role associated with these amino acid sequences. Homopolymer sequences are ... Within the coding sequences of eukaryotes, alternatively spliced exons are known to evolve under relaxed constraints in ... Here, we have tested the effect of splicing on the structure (composition, length) of homopolymer sequences in relation to the ... We observed a significant relationship between alternative splicing and homopolymer sequences with alternatively spliced genes ...https://www.dpag.ox.ac.uk/publications/237582
SMART: WD40 domain annotation
From the cDNA nucleotide sequence of the entire coding region, the primary structure of a 340-amino acid protein was deduced. ... Repetitive segmental structure of the transducin beta subunit: homology with the CDC4 gene and identification of related mRNAs. ... WD-40 repeats (also known as WD or beta-transducin repeats) are short ~40 amino acid motifs, often terminating in a Trp-Asp (W- ... 2014) Nucleic Acids Res doi: 10.1093/nar/gku949. Letunic et al. (2017) Nucleic Acids Res doi: 10.1093/nar/gkx922 ...http://smart.embl.de/smart/do_annotation.pl?DOMAIN=WD40&START=34&END=73&E_VALUE=4.11e-10&TYPE=SMART&BLAST=NYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWG
Mdv1p contains a novel NH2-terminal domain, a central c | Open-i
The coiled-coil domain (amino acids 241-303) was identified as described (Lupas et al. 1991). The amino acid regions of the WD ... The coiled-coil domain (amino acids 241-303) was identified as described (Lupas et al. 1991). The amino acid regions of the WD ... The coiled-coil domain (amino acids 241-303) w ... Repetitive Sequences, Amino Acid. *Saccharomyces cerevisiae/ ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC2192646_JCB0008020.f4&req=4
Enzymatic Strategies to Detoxify Gluten: Implications for Celiac Disease
Moreover, they contain domains with numerous repetitive sequences rich in those amino acids. Because of this glutamine- and ... Gliadins and glutenins have a unique amino acid composition with a high content of proline (15%), hydrophobic amino acids (19 ... In the case of A-gliadin, the single lysil residue occurring in the amino acid sequence (K-186) is assumed to act as an acyl ... Such tTG-catalyzed posttranslational modification generates negatively charged amino acid residues that bind with an increased ...https://www.hindawi.com/journals/er/2010/174354/
Upregulation of biglycan expression in dystrophic muscl | Open-i
Molecular Sequence Data. *Molecular Weight. *Neuromuscular Junction/chemistry. *Protein Binding. *Repetitive Sequences, Amino ... Amino Acid Sequence. *Animals. *Biglycan. *Binding Sites. *Chondroitin Sulfates/metabolism. *Dystroglycans. *Dystrophin/ ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC2169361_JCB9909134.f7&req=4
Biological Molecules Flashcards by Bel Thomas | Brainscape
They contain a limited range of R groups which are usually small, the amino acid sequence is repetitive, they are strong, ... Describe the 3 groups coming off a carbon atom in an amino acid. ... What effect does a C=C double bond have on a fatty acid chain? ... It causes a kink in the chain so they cannot pack as closely together leading to the fatty acid being liquid at RTP (oil not ... A fatty acid that contains one (monounsaturated) or more (polyunsaturated) C=C double bonds in it's chain. ...https://www.brainscape.com/flashcards/biological-molecules-5071978/packs/7505716
Advances and challenges in malaria vaccine development
DNA cloning of Plasmodium falciparum circumsporozoite gene: amino acid sequence of repetitive epitope. Science. 1984;225:628- ... 63). A recombinant P. falciparum LSA1 protein vaccine that includes the N-and C-terminal regions and two of the 17 amino acid ... although an amino acid change at residue 171 affects invasion-blocking antibodies (Ref. 154) and many children in Papua New ... Genome sequence of the human malaria parasite Plasmodium falciparum. Nature. 2002;419:498-511. [PMC free article] [PubMed] ...http://pubmedcentralcanada.ca/pmcc/articles/PMC2943423/
How Spiders Spin Silk
Spidroins are big proteins of up to 3,500 amino acids that contain mostly repetitive sequences. The non-repetitive N- and C- ... NASA's Swift satellite detected the strongest, hottest, and longest-lasting sequence of stellar flares ever seen from a nearby ...http://www.innovations-report.com/html/report/materials-science/how-spiders-spin-silk.html
Dictyostelium discoideum AX4 (ID 201) - BioProject - NCBI
... a large proportion of which have long stretches of repetitive amino acid sequences. In addition to the nuclear genome, D. ... Sequencing of the 34-Mb haploid genome of D. discoideum was undertaken on a chromosome-by-chromosome basis through an ... The Dictyostelium discoideum Sequencing Consortium. - Northwestern University, dictyBase, Center for Genetic Medicine, USA, ... Glöckner G et al., "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.", Nature, 2002 Jul 4;418(6893):79-85 ...https://www.ncbi.nlm.nih.gov/bioproject?LinkName=nuccore_bioproject&from_uid=90970782
Ankyrin repeat | definition of ankyrin repeat by Medical dictionary
A short repetitive sequence of amino acids consisting of a beta strand followed by two alpha helices and a beta strand. The ...http://medical-dictionary.thefreedictionary.com/Ankyrin+repeat
US9109047B2 - High molecular ordered fibrilar structures, method for their preparation and uses thereof - Google...
These proteins are distinguished by their repetitive amino acid sequences that confer their mechanical properties such as ... Thus, "Amino acid" refers to naturally occurring and synthetic amino acids, as well as amino acid analogs and amino acid ... "amino acid" or "amino acids" is understood to include the 20 naturally occurring amino acids; those amino acids often modified ... An amino acid sequence (peptide) or a nucleic acid is said to be a homolog of a corresponding amino acid sequence, peptide or a ...https://patents.google.com/patent/US9109047B2/en
"Secondary Structure Adopted by the Gly-Gly-X Repetitive Regions of Dra" by Geoffrey M Gray, Arjan van der Vaart et al.
... which is one of the most common structural repetitive motifs found in orb-weaving dragline spider silk proteins. The ... Amino Acid Sequence, Animals, Fibroins, Molecular Dynamics Simulation, Nuclear Magnetic Resonance, Biomolecular, Protein ... Secondary Structure Adopted by the Gly-Gly-X Repetitive Regions of Dragline Spider Silk ... which is one of the most common structural repetitive motifs found in orb-weaving dragline spider silk proteins. The ...http://scholarcommons.usf.edu/chm_facpub/16/
BNR/Asp-box repeat - Wikipedia
BNR/Asp-box repeat is a repetitive sequence of amino acids contained in some proteins. Members of this family contain multiple ... Ponting, CP; Russell, RB; Copley, RR (2001). "Sialidase-like Asp-boxes: sequence-similar structures within different protein ...https://en.wikipedia.org/wiki/BNR/Asp-box_repeat
The American Journal of Tropical Medicine and Hygiene | Repeated Immunogenic Amino Acid Sequences of Plasmodium Species Share...
Six published repetitive immunogenic amino acid sequences from the circumsporozoite (CS) antigen, ring-infected erythrocyte ... amino acid sequences between tandemly repeated Plasmodium amino acid sequences and the human and human viral sequences compiled ... Matches of at least 4 amino acids were found for all sequences. In the database, 29 matches were found for human proteins and ... 26 matches were found for human viruses with the 6 antigen sequences. Most of the matched proteins, and many of the matched ...http://www.ajtmh.org/content/journals/10.4269/ajtmh.1987.37.258
W232 is necessary for full AvrBs3 activity. (A) Schemat | Open-i
The amino acid sequence of repeat −1 is given; resid ... Repetitive Sequences, Amino Acid. *Thymine/chemistry. * ... The amino acid sequence of repeat −1 is given; residue W232 is highlighted. (B) Relative GUS activity (%) induced by AvrBs3 and ... The amino acid sequence of repeat −1 is given; residue W232 is highlighted. (B) Relative GUS activity (%) induced by AvrBs3 and ... However, substitutions of W232 by the aromatic amino acids tyrosine (W232Y) and phenylalanine (W232F) retained the highest ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC4066769_gku341fig2&req=4
Structure of the Smyd3-AdoHcy complex. (A) Overall st | Open-i
Repetitive Sequences, Amino Acid. *S-Adenosylhomocysteine/chemistry. Related in: MedlinePlus. © Copyright Policy - creative- ... Xu S, Wu J, Sun B, Zhong C, Ding J - Nucleic Acids Res. (2011) ... Xu S, Wu J, Sun B, Zhong C, Ding J - Nucleic Acids Res. (2011) ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC3105404_gkr019f1&req=4
Histone binding pocket. (A) Potential histone peptide b | Open-i
Repetitive Sequences, Amino Acid. *S-Adenosylhomocysteine/chemistry. Related in: MedlinePlus. © Copyright Policy - creative- ... Xu S, Wu J, Sun B, Zhong C, Ding J - Nucleic Acids Res. (2011) ... Xu S, Wu J, Sun B, Zhong C, Ding J - Nucleic Acids Res. (2011) ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC3105404_gkr019f2&req=4
Chemical Concepts < Alchemy Center @ Wellness Advocate ....
Amino Acid Repetitive Sequences + *Base Sequence *AT Rich Sequence *GC Rich Sequence *CpG Islands *Matrix Attachment Regions * ... Nucleic Acid Regulatory Sequences + *Nucleic Acid Repetitive Sequences + *Binding Sites *Competitive Binding *Antibody Binding ... Amino Acid Sequence *Exteins *Histone Code *Immunoglobulin Variable Region + *Inteins *Peptide Library *Protein Sorting Signals ... Carbohydrate Sequence *conserved sequence *consensus sequence *position-specific scoring matrix *Isomerism *Molecular ...http://wellnessadvocate.com/?dgl=88400
Modular Design in Natural and Biomimetic Soft Materials.
2.2.1. Linear Elastin Mimicking Model Systems Once the primary repetitive amino acid sequence for tropoelastin was obtained, ... which in the case of elastin can be occupied by any amino acid other than proline. (The single-letter codes for amino acids are ... a) Concept of a sticky-end assembly process together with the designed amino acid sequences. Complementary charges in companion ... Modular amino acids and -amino alcohol-based chiral ligands for enantioselective addition of diethylzinc to aromatic aldehydes. ...https://www.docme.ru/doc/1938148/modular-design-in-natural-and-biomimetic-soft-materials
Cellular Reprogramming: a novel tool for investigating autism spectrum disorders
TAL effector proteins consist of repetitive 33-35 amino acid sequences that are highly conserved except for two amino acids of ... Those two key amino acids determine the specificity of TALEN binding to target DNA sequence . TALENs showed much less off ... which recognize 3 bp of DNA sequence. DNA binding domain of ZFN is designed to target specific DNA sequence. The number of zinc ... Nucleic acids research. 2011;39:9283-9293. [PMC free article] [PubMed]. 103. Li XJ, Zhang X, Johnson MA, Wang ZB, Lavaute T, ...http://pubmedcentralcanada.ca/pmcc/articles/PMC3785941/?lang=en-ca
Silkworms transformed with chimeric silkworm/spider silk genes spin composite silk fibers with improved mechanical properties |...
These genes and their products are highly repetitive, with correlations between certain short, repetitive amino acid sequence ... One is the use of the 2.4-kbp A2S814 synthetic spider silk sequence encoding repetitive flagelliform-like (GPGGA)8 elastic and ... due to the highly repetitive nature of the spider silk sequences, anomalous migration of the protein products on SDS/PAGE, and/ ... The spidroin sequence was fused to a downstream sequence encoding a C-terminal fhc peptide. The transgenic silkworm isolated ...https://www.pnas.org/content/109/3/923.long
Joseph (Jody) Puglisi | Stanford Medicine Profiles
... machine that translates the genetic code contained in the messenger RNA into an amino acid sequence through repetitive cycles ... Amino acid sequence repertoire of the bacterial proteome and the occurrence of untranslatable sequences PROCEEDINGS OF THE ... Bioinformatic analysis of Escherichia coli proteomes revealed that all possible amino acid triplet sequences occur at their ... and continues by translating a new sequence of amino acids. Despite extensive biochemical and genetic studies, there is no ...https://med.stanford.edu/profiles/joseph-puglisi
Steven Chu | Stanford Medicine Profiles
... machine that translates the genetic code contained in the messenger RNA into an amino acid sequence through repetitive cycles ... Telomeres, repetitive DNA sequences at chromosome ends, are shielded against the DNA damage response (DDR) by the shelterin ... Moreover, dimerization and signaling of KRas are both dependent on an intact CAAX (C, cysteine; A, aliphatic; X, any amino acid ... A critical element in selecting correct transfer RNA (tRNA) transferring correct amino acid is "induced fit" between the ...https://med.stanford.edu/profiles/steve-chu
Structural cell wall proteins from five pollen species and their relationship with boron
They contain highly repetitive sequence domains in which hydroxyproline (Hyp) is a major amino acid (Showalter, 1993). ... HRGPs are the most abundant structural proteins in maize sexual tissues and since (Hyp) is an amino acid resulting from post- ... Here, we show that maize pollen accumulated a significant pool of hydroxyproline (Hyp) and 63% of this amino acid was localized ... For HRGPs immunolocalization, pollen tubes were fixed in FAA [10% (v/v) formaldehyde, 5% (v/v) acetic acid, and 50% ethanol] ...http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-04202005000400005&lng=en&tlng=en