*  Tissue and gene specificity of mouse renin expression. | Hypertension
In contrast, kidney renin levels appear to be unaffected by the gene duplication. Sequence analysis of a 319 bp renin cDNA ... Tissue and gene specificity of mouse renin expression.. L J Field, R A McGowan, D P Dickinson, K W Gross ... Some strains of mice appear to carry a duplication of the renin structural gene (Ren-2) near the Ren-1 locus. Strains with the ... Moreover, a single base substitution of A for G at residue #996 in the kidney renin mRNA creates a potential glycosylation ...
  http://hyper.ahajournals.org/content/6/4/597
*  α-Adrenoceptors and Age-Dependent Decrease of Plasma Renin Activity in Essential Hypertension | Clinical Science
3. The maximum increment of plasma renin activity was inversely related to age and the dose-response curve of plasma renin ... α-Adrenoceptors and Age-Dependent Decrease of Plasma Renin Activity in Essential Hypertension. A. Salvetti, R. Pedrinelli, F. ... 2. Phentolamine caused a dose-related increase of plasma renin activity, which was independent of mean blood pressure and heart ... α-Adrenoceptors and Age-Dependent Decrease of Plasma Renin Activity in Essential Hypertension ...
  http://www.clinsci.org/content/61/s7/311s
*  Abstract 191: Transcriptional Regulation of Renin by Nuclear Receptors Co-regulated With Renin | Hypertension
Abstract 191: Transcriptional Regulation of Renin by Nuclear Receptors Co-regulated With Renin. Ko-Ting Lu, Eric T Weatherford ... We tested the hypothesis that a nuclear receptor that is co-regulated with renin may participate in renin gene regulation. To ... Abstract 191: Transcriptional Regulation of Renin by Nuclear Receptors Co-regulated With Renin ... Abstract 191: Transcriptional Regulation of Renin by Nuclear Receptors Co-regulated With Renin ...
  http://hyper.ahajournals.org/content/62/Suppl_1/A191
*  Evidence for an extrarenal source of inactive renin in rats. | Hypertension
Inactive renin was separated from active renin by a Cibacron blue column, and the 0 time inactive renin eluted in the same ... In summary, inactive renin is present in the anephric rat and does not appear to be converted to active renin in the peripheral ... Active renin rapidly decreased after bilateral nephrectomy, with a half-life of approximately 15 minutes. Inactive renin, on ... The pH optimum of inactive renin in rat renin substrate was between 5.5 and 7.5, which differs from the optimal value of pepsin ...
  http://hyper.ahajournals.org/content/6/5/627
*  Identification of Renin and Renin-like Enzymes in Rat Brain by a Renin-Specific Antibody | Clinical Science
Identification of Renin and Renin-like Enzymes in Rat Brain by a Renin-Specific Antibody. V. J. Dzau, Amy Brenner, Neremiah ... Identification of Renin and Renin-like Enzymes in Rat Brain by a Renin-Specific Antibody ... Identification of Renin and Renin-like Enzymes in Rat Brain by a Renin-Specific Antibody ... Identification of Renin and Renin-like Enzymes in Rat Brain by a Renin-Specific Antibody ...
  http://www.clinsci.org/content/59/s6/45s
*  A radiochemical renin assay | Biochemical Journal
1. A synthetic 3-([14C]valine)-labelled tetradecapeptide renin substrate was used to measure renin concentration. Renin ... A radiochemical renin assay. F. A. Mendelsohn, C. I. Johnston. Biochemical Journal Jan 01, 1971, 121 (2) 241-244; DOI: 10.1042/ ... 2. The rate of conversion of the substrate into angiotensin I was shown to be linearly related to renin concentration and time ... It is suggested that the use of a pure substrate offers advantages that include the standardization of current units of renin ...
  http://www.biochemj.org/content/121/2/241
*  A Genetic Variant in the Distal Enhancer Region of the Human Renin Gene Affects Renin Expression - pdf descargar
A Genetic Variant in the Distal Enhancer Region of the Human Renin Gene Affects Renin Expression. . Biblioteca virtual para ... A Genetic Variant in the Distal Enhancer Region of the Human Renin Gene Affects Renin Expression - Descarga este documento en ... A Genetic Variant in the Distal Enhancer Region of the Human Renin Gene Affects Renin Expression. ... The results suggest that variants in the enhancer region of the human renin gene have an effect on the expression levels of ...
  http://libros.duhnnae.com/2017/jun9/149846632086-A-Genetic-Variant-in-the-Distal-Enhancer-Region-of-the-Human-Renin-Gene-Affects-Renin-Expression.php
*  Control of renin release in isolated rat glomeruli. | Hypertension
Control of renin release in isolated rat glomeruli.. W H Beierwaltes, S Schryver, P S Olson, J C Romero ... These results suggest that basal renin and ISO-stimulated renin are released via different mechanisms. ... Basal renin was approximately 3 ng AI/ml/hr. Beta-adrenergic stimulation with isoproterenol (ISO), 178 micron M, increased ... Increasing Krebs potassium (50 mM) increased basal renin fourfold (14 ng AI) while the absolute increase from basal due to ISO ...
  http://hyper.ahajournals.org/content/3/6_Pt_2/II-30
*  Renin FRET Substrate I
... also called Renin Substrate I in some literature) contains a renin cleavage site that occurs in the N-terminal peptide of human ... The kinetics of renin-catalyzed hydrolysis of this substrate is shown to be consistent with a simple substrate inhibition model ... The substrate can detect renin as low as 30 ng/mL after an incubation of only 3-5 min.; Minimum Purity: 95%; DABCYL-g-Abu- ... Cleavage of the substrate occurs specifically at the Leu-Val bond and corresponds to the renin cleavage site of angiotensinogen ...
  https://www.anaspec.com/products/product.asp?id=48589&productid=17790
*  Modulation of episodic renin release during sleep in humans. | Hypertension
Modulation of episodic renin release during sleep in humans.. G Brandenberger, M O Krauth, J Ehrhart, J P Libert, C Simon, M ... Modulation of episodic renin release during sleep in humans.. G Brandenberger, M O Krauth, J Ehrhart, J P Libert, C Simon and M ... Modulation of episodic renin release during sleep in humans.. G Brandenberger, M O Krauth, J Ehrhart, J P Libert, C Simon and M ... Similarly, a low sodium diet, which led to a slow increase in renal renin content, provoked large oscillations with high ...
  http://hyper.ahajournals.org/content/15/4/370
*  Gentaur Molecular :Molecular Innovations \ RENIN PRORENIN Rat Renin Prorenin Double Depleted Plasma \ RPLA-SC-PREN
RENIN_PRORENIN Rat Renin_Prorenin Double Depleted Plasma \ RPLA-SC-PREN for more molecular products just contact us ... Index / Molecular Innovations / RENIN_PRORENIN Rat Renin_Prorenin Double Depleted Plasma / Product Detail : RPLA-SC-PREN RENIN_ ... We have also other products like : RENIN_PRORENIN Rat Renin_Prorenin Double Depleted Plasma. Related products : RENIN_PRORENIN ... RPLA-SC-PREN RENIN_PRORENIN Rat Renin_Prorenin Double Depleted Plasma Ask technical file . ...
  http://www.antibody-antibodies.com/product_det.php?id=2627201&supplier=search&name=%20RENIN_PRORENIN%20Rat%20Renin_Prorenin%20Double%20Depleted%20Plasma
*  Relation between blood pressure and renin, renin substrate, angiotensin II, aldosterone and urinary sodium and potassium in 574...
Renin, renin substrate, angiotensin II, aldosterone and urinary sodium and potassium were compared with blood pressure to ... Relation between blood pressure and renin, renin substrate, angiotensin II, aldosterone and urinary sodium and potassium in 574 ... Relation between blood pressure and renin, renin substrate, angiotensin II, aldosterone and urinary sodium and potassium in 574 ... Relation between blood pressure and renin, renin substrate, angiotensin II, aldosterone and urinary sodium and potassium in 574 ...
  http://hyper.ahajournals.org/content/1/3/287
*  Studies on the Effect of Angiotensin II and of Des1-angiotensin II on Blood Pressure, Plasma Renin Activity and Plasma...
2. Plasma renin activity was equally suppressed by both compounds. The increase in blood pressure induced by the heptapeptide ... Studies on the Effect of Angiotensin II and of Des1-angiotensin II on Blood Pressure, Plasma Renin Activity and Plasma ... Studies on the Effect of Angiotensin II and of Des1-angiotensin II on Blood Pressure, Plasma Renin Activity and Plasma ... Studies on the Effect of Angiotensin II and of Des1-angiotensin II on Blood Pressure, Plasma Renin Activity and Plasma ...
  http://www.clinsci.org/content/51/s3/147s
*  New Renin Inhibitor VTP-27999 Alters Renin Immunoreactivity and Does Not Unfold ProreninNovelty and Significance | Hypertension
Studies With Renin. To verify whether VTP-27999 affected the detection of renin, we quantified recombinant human renin in ... The renin inhibitor VTP-27999 increases renin immunoreactivity in renin immunoassays most likely because it affects the ... VTP-27999 binding to renin increases its immunoreactivity in renin IRMAs, thereby resulting in an overestimation of the renin ... First, VTP-27999 binding to renin increases renin immunoreactivity in 2 different renin IRMAs. Second, in contrast to aliskiren ...
  http://hyper.ahajournals.org/content/61/5/1075
*  Angiotensin subtype-2 receptors inhibit renin biosynthesis and angiotensin II formation. - Semantic Scholar
We monitored changes in renal Ang II, renin mRNA and protein expression, and plasma renin concentration (PRC) in response to ... Renin mRNA increased 63% during LS, and either valsartan or PD increased it further by 600% and 250% from NS and 538% and 187% ... Similarly, renal renin content and PRC increased in response to LS and increased further in response to combined LS and ... Immunostaining for renal renin protein demonstrated an increase in its expression in juxtaglomular and tubular cells during LS ...
  https://www.semanticscholar.org/paper/Angiotensin-subtype-2-receptors-inhibit-renin-bios-Siragy-Xue/0cc273503bf8d60dfb2419a18439a53c839ed97c
*  Exchangeable Sodium in Experimental Hypertension in Rats | Clinical Science
4. The fact that both plasma renin levels and exchangeable sodium levels increase according to this method, suggests that ... which developed severe hypertension had a marked increase in exchangeable sodium with a concomitant rise in plasma renin; the ... removal of the other kidney produced severe hypertension with no significant changes in exchangeable sodium or plasma renin ...
  http://www.clinsci.org/content/51/s3/133s
*  Effects of Renal Arterial Infusion of Sodium and Potassium on Renin Secretion in the Dog | Circulation Research
Effects of Renal Arterial Infusion of Sodium and Potassium on Renin Secretion in the Dog. ROBERT E. SHADE, JAMES O. DAVIS, J. ... An increase in renal venous plasma sodium concentration from 141 to 154-158 mEq/liter caused no change in renin secretion for ... The nonfiltering kidney model was used to determine whether sodium or potassium inhibits renin secretion in the absence of a ... In contrast, dogs with thoracic caval constriction but with a filtering kidney showed a striking decrease in renin secretion ...
  http://circres.ahajournals.org/content/31/5/719
*  Angiotensin II Stimulates Renin in Inner Medullary Collecting Duct Cells via Protein Kinase C and Independent of Epithelial...
In primary cultures of inner medullary CD cells, renin mRNA and (pro)renin protein levels increased with Ang II (100 nmol/L), ... However, inhibition of protein kinase C with calphostin C prevented the Ang II-mediated increases in renin mRNA and (pro)renin ... medullary renin mRNA, urinary renin content, and intrarenal Ang II levels. Amiloride cotreatment did not alter these responses ... on CD renin expression and urinary renin content in Ang II-infused rats (80 ng/min, 2 weeks). Ang II infusion increased ...
  http://hyper.ahajournals.org/content/early/2011/01/31/HYPERTENSIONAHA.110.165902
*  Arterial wall uptake of renal renin and blood pressure control. | Hypertension
Bolus injections of renin sufficient to elevate blood pressure by 44.7 mm Hg caused aortic renin to rise from 0.13 to 1.48 ng ... We have studied the contribution of circulating renin of renal origin to renin-like activity within the arterial wall and to ... renin-like activity within the aortic wall is derived from plasma renin and it seems probable that this component of the renin- ... Arterial wall uptake of renal renin and blood pressure control.. M Loudon, R F Bing, H Thurston, J D Swales ...
  http://hyper.ahajournals.org/content/5/5/629
*  Evidence for Hemodynamic Autoregulation of Renin Release | Circulation Research
... renin release remained high. Therefore, renin release appears to be related to autoregulated dilatation of the renal arterioles ... Renin release, determined by both bioassay and radioimmunoassay, averaged 2.7 ± 0.9 (SE) µg/min at control pressure and ... Evidence for Hemodynamic Autoregulation of Renin Release. IVAR EIDE, EINAR LOslash;YNING, FREDRIK KIIL ... However, renin release then remained constant during further lowering of arterial perfusion pressure despite reductions in ...
  http://circres.ahajournals.org/content/32/2/237
*  Characterization of recombinant human prorenin and renin. | Hypertension
Characterization of recombinant human prorenin and renin.. C T Carilli, J L Vigne, L C Wallace, L M Smith, M A Wong, J A ... Characterization of recombinant human prorenin and renin.. C T Carilli, J L Vigne, L C Wallace, L M Smith, M A Wong, J A ... Characterization of recombinant human prorenin and renin.. C T Carilli, J L Vigne, L C Wallace, L M Smith, M A Wong, J A ... The purified inactive prorenin was not a substrate for active renin and was not capable of self-activation. Prorenin could be ...
  http://hyper.ahajournals.org/content/11/6_Pt_2/713
*  High-Renin Essential Hypertension: Adrenergic Cardiovascular Correlates | Clinical Science
High-Renin Essential Hypertension: Adrenergic Cardiovascular Correlates. M. Esler, S. Julius, O. Randall, V. Dequattro, A. ... High-Renin Essential Hypertension: Adrenergic Cardiovascular Correlates. M. Esler, S. Julius, O. Randall, V. Dequattro, A. ... High-Renin Essential Hypertension: Adrenergic Cardiovascular Correlates Message Subject (Your Name) has forwarded a page to you ... The high plasma renin activity is seen as an expression of sympathetic nervous system overactivity. ...
  http://www.clinsci.org/content/51/s3/181s
*  Aldosterone and Renin | SpringerLink
Plasma Renin Activity Congenital Adrenal Hyperplasia Primary Aldosteronism Plasma Aldosterone Zona Glomer These keywords were ... Homer, J. M., Hintz, R. L., and Luetscher, J. A., 1979, The role of renin and angiotensin in salt-losing, 21-hydroxylase ... Lemal, J. M., Rapaport, R., and Bayard, F., 1976, Plasma aldosterone, renin activity, and 17a-hydroxyprogesterone in salt- ... Biglieri E.G. (1985) Aldosterone and Renin. In: Ingbar S.H. (eds) Contemporary Endocrinology. Contemporary Endocrinology (( ...
  https://link.springer.com/chapter/10.1007/978-1-4684-4817-7_5
*  Aldosterone and Renin
Renin is an enzyme that controls aldosterone production. Aldosterone and renin tests help diagnose primary (Conn syndrome) and ... Renin is an enzyme that controls aldosterone production. These tests measure the levels of aldosterone and renin in the blood ... blood levels of aldosterone and renin are measured and a calculation is done by dividing the aldosterone result by the renin ... The kidneys release renin when there is a drop in blood pressure or a decrease in sodium chloride concentration in the tubules ...
  https://labtestsonline.org/tests/aldosterone-and-renin
*  Renin-1 (P06281) | InterPro | EMBL-EBI
InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.
  http://www.ebi.ac.uk/interpro/protein/P06281