Loading...


*  Social supports and serotonin transporter gene moderate depression in maltreated children | PNAS
... decreased cortical γ-aminobutyric acid measured in vivo using proton magnetic resonance spectroscopy (12), and multiple ... SLC6A4 has a well studied functional variable number of tandem repeats (VNTR) polymorphism in the promoter region; the variant ... and reduction in hippocampal volume, a brain structure vulnerable to the neurotoxic effects of stress-induced elevations in ... The s allele of 5-HTTLPR contains an attenuated promoter segment and is associated with reduced transcription and functional ...
  http://www.pnas.org/content/101/49/17316.long
*  Preclinical Imaging: an Essential Ally in Modern Biosciences | SpringerLink
Forster D, Davies K, Williams S. Magnetic resonance spectroscopy in vivo of neurochemicals in a transgenic model of Alzheimer's ... Reduction and Refinement) policies. The most suitable modalities for small-animal in vivo imaging applications are based on ... with highly sensitive techniques providing functional information, such as micro-PET or micro-SPECT, will continue to broaden ... magnetic resonance imaging (MRI), magnetic resonance spectroscopy imaging (MRSI), and ultrasound. Each modality has intrinsic ...
  https://link.springer.com/article/10.1007%2Fs40291-013-0062-3
*  Gasex 100 caps. Quality online Gasex OTC.
Anatomy and physiology of subcutaneousadipose tissue by in vivo magnetic resonance imaging and spectroscopy: relationships ... The next majortask in the kinematic data reduction is to assign specific clinically recogniz-able joint positions, such as ... Understanding the childрs functional possibilitiesmeans the therapist can avoid frustrating them with unreasonable demandsand ... help their parents understand reasonable functional goals for the child. The first manifestation may be asymmetrical dis-tal ...
  http://www.envelopemachines.com/industry/qualification29/format12/
*  Frontiers | Genetic Pharmacotherapy as an Early CNS Drug Development Strategy: Testing Glutaminase Inhibition for Schizophrenia...
Thus, a genetically induced glutaminase reduction - mimicking pharmacological inhibition - strongly attenuated the response to ... One month after tamoxifen treatment of adult GLS1 iHET mice, we found a 50% reduction in GLS1 allelic abundance and glutaminase ... One month after tamoxifen treatment of adult GLS1 iHET mice, we found a 50% reduction in GLS1 allelic abundance and glutaminase ... C-precursor flux through astrocytes to neurons and the conversion of glutamine to glutamate by magnetic resonance spectroscopy ...
  https://www.frontiersin.org/articles/10.3389/fnsys.2015.00165/full
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
To help improve this understanding, proton magnetic resonance spectroscopy (1H-MRS) can be used as it allows the in vivo ... lines which can be expanded and used for in vivo transplantation. In vivo transplanted SMSc behave as functional, tissue- ... Myopathic zebrafish typically show an overall reduction in birefringence, reflecting the disorganization of sarcomeres. The ... magnetic resonance imaging, MRI, magnetic resonance spectroscopy, MRS, spectroscopy, imaging, cell tracking, clinical ...
  https://www.jove.com/visualize/abstract/23613869/combined-mri-p-mrs-investigations-acta1-h40y-mouse-model-nemaline
*  Optical spectroscopy in therapy response monitoring: an awakening giant | Spectroscopy Europe/Asia
In the case of breast tumours, diagnosis by X-ray, mammography, magnetic resonance imaging (MRI) and ultrasound (US) methods ... "Quantitative diffuse reflectance and fluorescence spectroscopy: tool to monitor tumor physiology in vivo", J. Biomed. Opt. 14, ... A reduction in tumour size is considered as the gold standard for assessing the effectiveness of treatment. Conventional ... However, several functional changes often precede this morphological variability.3 Optical spectroscopic methods offer non- ...
  https://www.spectroscopyeurope.com/article/optical-spectroscopy-therapy-response-monitoring-awakening-giant
*  Frontiers | Mapping Pathological Phenotypes in Reelin Mutant Mice | Pediatrics
At the end of the behavioural studies, we conducted high performance liquid chromatography and magnetic resonance imaging and ... spectroscopy to investigate whether reelin mutation influences brain monoamine and metaboli... ... At the end of the behavioural studies, we conducted high performance liquid chromatography and magnetic resonance imaging and ... spectroscopy to investigate whether reelin mutation influences brain monoamine and metabolites levels in regions involved in ...
  https://www.frontiersin.org/articles/10.3389/fped.2014.00095/full
*  Biology and therapy of fibromyalgia. Functional magnetic resonance imaging findings in fibromyalgia | Arthritis Research &...
This article provides an overview of the nociceptive system as it functions normally, reviews functional brain imaging methods ... Techniques in neuroimaging such as functional magnetic resonance imaging (fMRI) have helped to provide insights into the role ... Yet another new approach, magnetic resonance spectroscopy, obtains spectra of multiple selected regions and determines the ... This method has been applied to patients with chronic low back pain, showing reductions of N-acetyl-aspartate and glucose in ...
  https://arthritis-research.biomedcentral.com/articles/10.1186/ar2094
*  Regulation of In Vivo Mitochondrial Energetics by Oxidative Stress throughout Life: A Multi-Modal Spectroscopy Approach
Aging; Magnetic Resonance Spectroscopy; Mitochondria; Optical Spectroscopy; Oxidative Stress. en_US. dc.subject.other. ... Oxidative stress-induced reduction of mitochondrial coupling efficiency has been implicated as a negative feedback mechanism ... a new way of thinking about age-related functional losses, and a promising suggestion that targeting mitochondrial oxidative ... concentrations using 31P magnetic resonance spectroscopy and tissue oxygenation using near infrared optical spectroscopy in ...
  https://digital.lib.washington.edu/researchworks/handle/1773/20899?show=full
*  Functional Neuroimaging in Exercise and Sport Sciences - beck-shop.de
... near infrared spectroscopy (NIRS), magnetic resonance imaging (MRI) to positron emission tomography (PET). All of these imaging ... stress reduction, anxiolysis, and hypoalgesia. Today, modern functional neuroimaging techniques afford direct measurement of ... as well as the correlation of the derived physiological in vivo signals with behavioral outcomes recorded during and after ... Functional Neuroimaging in Exercise and Sport Sciences. Regular physical exercise is associated with substantial health ...
  http://m.beck-shop.de/item/3130303735363932
*  Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer | Breast Cancer Research | Full Text
Metabolic changes were assessed by ex vivo high-resolution magic angle spinning magnetic resonance spectroscopy. Using a novel ... Metabolic changes were assessed by ex vivo high-resolution magic angle spinning magnetic resonance spectroscopy. ... Functional biomarkers such as pAktser473, which more directly is linked to signal transduction activity, may therefore have ... Further, we observed a marked reduction of pAktser473 levels in response to treatments targeting the PI3K pathway in the basal- ...
  https://breast-cancer-research.biomedcentral.com/articles/10.1186/bcr3391
*  Neuropathology of stress | SpringerLink
A recent study used multimodal in vivo imaging, incorporating structural magnetic resonance imaging (MRI), and MR spectroscopy ... there is a clear effect of early life stress or stress in adulthood on reductions in volume and alteration in functional ... Magnetic resonance spectroscopy identifies neural progenitor cells in the live human brain. Science 318:980-985PubMedGoogle ... Normal sexual dimorphism of the adult human brain assessed by in vivo magnetic resonance imaging. Cereb Cortex 11:490-497PubMed ...
  https://link.springer.com/article/10.1007%2Fs00401-013-1223-5
*  UAEU Course Catalog
... magnetic resonance imaging (MRI) and spectroscopy (MRS), Nuclear Medicine (SPECT, PET Imaging). Functional and multi- ... S-matrix and reduction formula; Green's functions in path integral formalism; perturbation theory and Feynman diagrams; ... in vivo NMR spectroscopy. ... magnetic field and magnetic forces, sources of magnetic fields ... Advanced Magnetic Resonance (PHYS778). Signal acquisition and k-space sampling, image reconstruction techniques, filtering and ...
  http://www.uaeu.ac.ae/en/catalog/courses/course_2957.shtml?id=PHYS105
*  Lead Poisoning Imaging: Practice Essentials, Radiography, Computed Tomography
Trope et al found that that magnetic resonance spectroscopy (MRS) may have a role as a noninvasive technique for the in vivo ... Functional MRI now offers the means to noninvasively study this plastic reorganization of the brain in children and adults. MRI ... More specifically, they found significant reductions in the levels of brain metabolites in gray matter but not white matter in ... Magnetic resonance imaging and spectroscopy of regional brain structure in a 10-year-old boy with elevated blood lead levels. ...
  https://emedicine.medscape.com/article/410113-overview
*  Huntington's disease biomarkers and therapeutics - Wenzhen Duan
... in vivo structural magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS), to determine if these measures ... We will determine the correlation between MRI measures and functional impairment in HdhQ250 mice with or without treatment. In ... The key issues are whether these measures truly reflect the reduction or dysfunction of medium spiny neurons - the nerve cells ... and determine whether these metabolites respond to neuroprotective treatment by use of magnetic resonance spectroscopy in full- ...
  http://grantome.com/grant/NIH/R01-NS082338-02
*  Publications | Bangor Imaging Unit (BIU) | Bangor University
Event-related dynamics of glutamate and BOLD effects measured using functional magnetic resonance spectroscopy (fMRS) at 3T in ... Lindner, M., Bell, T., Iqbal, S., Mullins, P. G., & Christakou, A. (2017). In vivo functional neurochemistry of human cortical ... Lawley, J. S., Macdonald, J. H., Oliver, S. J., & Mullins, P. G. (2016). Unexpected reductions in regional cerebral perfusion ... Downing, P. E., Wiggett, A., Peelen, M.V. (2007). Functional magnetic resonance imaging investigation of overlapping lateral ...
  https://www.bangor.ac.uk/psychology/biu/publications.php.en
*  Is magnetic resonance imaging a plausible biomarker for upper motor neuron degeneration in amyotrophic lateral sclerosis...
Estimation of brainstem neuronal loss in amyotrophic lateral sclerosis with in vivo proton magnetic resonance spectroscopy. ... including proton magnetic resonance spectroscopy (1H-MRS), functional MRI (fMRI), diffusion tensor imaging (DTI), and ... NAA reduction in the brainstem has also been reported in ALS patients who have prominent UMN or bulbar signs49. ... Proton magnetic resonance spectroscopy of the motor cortex in 70 patients with amyotrophic lateral sclerosis. Arch Neurol 2001; ...
  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000700012&lng=en&nrm=iso&tlng=en
*  Neuroscience and intelligence - Wikipedia
... in vivo magnetic resonance spectroscopy) argues that human intelligence arises from a distributed and integrated neural network ... Their review of a wealth of data from functional imaging (functional magnetic resonance imaging and positron emission ... Comprehensive policy recommendations targeting reduction of cognitive impairment in children have been proposed. Biology portal ... McDaniel, M. A. (2005). "Big-brained people are smarter: A meta-analysis of the relationship between in vivo brain volume and ...
  https://en.wikipedia.org/wiki/Neuroscience_and_intelligence
*  Protocols and Video Articles Authored by Shingo Yasuhara (Translated to Hindi)
Vivo में माइक्रो परिसंचरण कंकाल की मांसपेशी में अंतरराज्यीय महत्वपूर्ण माइक्रोस्कोपी द्वारा मापन' ... Proton nuclear magnetic resonance (1H NMR) spectroscopy can detect mobile lipids in vivo. To examine the local effects of burn ... At the functional level, a significant decrease in isoproterenol-induced lipolytic activity (glycerol production) was observed ... NO donor increased IRS-1 ubiquitination, and proteasome inhibitors blocked NO donor-induced reduction in IRS-1 expression in ...
  https://www.jove.com/author/Shingo_Yasuhara?language=Hindi
*  JCI - Cardiovascular nuclear magnetic resonance: basic and clinical applications
Functional oxygen-17 magnetic resonance imaging and localized spectroscopy. Adv. Exp. Med. Biol. 2003. 510:213-218. View this ... In vivo measurement of cerebral oxygen consumption and blood flow using 17O magnetic resonance imaging. Magn. Reson. Med. 1991 ... The trend has been toward faster imaging sequences and the reduction of artifacts, while spectroscopy development has ... Functional and metabolic evaluation of the athlete's heart by magnetic resonance imaging and dobutamine stress magnetic ...
  https://www.jci.org/articles/view/18868
*  Atomic-scale dynamics inside living cells explored by neutron scattering | Journal of The Royal Society Interface
... apparent diffusion coefficient of water in biological tissues and in the brain has been measured by nuclear magnetic resonance ... 1996a,b, 1997, 1998, 1999). Recently, we presented a dynamical mapping of macromolecular dynamics in vivo, on the full ps-ns ... 2007 The 'wet mind': water and functional neuroimaging. Phys. Med. Biol. 52, R57-R90. (doi:10.1088/0031-9155/52/7/R02). ... Single-particle neutron spectroscopy provides a direct measurement of atomic and molecular motions on the ps-ns time scale. ...
  http://rsif.royalsocietypublishing.org/content/6/Suppl_5/S611
*  Protocols and Video Articles Authored by Slobodan I. Macura
Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring' ... we employed in vivo 16.4 T proton magnetic resonance spectroscopy. We utilized type 1 equilibrative nucleoside transporter ( ... functional magnetic resonance imaging, chemical shift imaging, heteronuclear imaging, and (1)H or (31)P MR spectroscopy. ... The reduction in high signal T2-weighted lesion volume may be an important outcome measure in future clinical trials in humans. ...
  https://www.jove.com/author/Slobodan+I._Macura
*  Pulmonary Drug Delivery: Advances and Challenges | Drug Formulation & Delivery | Pharmaceutical & Medicinal Chemistry |...
7.5.2 Nuclear Magnetic Resonance 153. 7.5.3 Infrared Spectroscopy 156. 7.5.4 Differential Scanning Calorimetry 157 ... 2. The Role of Functional Lung Imaging in the Improvement of Pulmonary Drug Delivery 19. Andreas Fouras and Stephen Dubsky ... 5.1.1 In vivo Fate of Inhaled Poorly Water-soluble Drugs 89 ... 5.5 Reduction of Size to Micro-/Nanoparticles 100. 5.5.1 ... 2.1.3 The Role of Functional Lung Imaging in Pulmonary Drug Delivery 22 ...
  https://www.wiley.com/en-us/Pulmonary+Drug+Delivery%3A+Advances+and+Challenges-p-9781118799543
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
For years, our laboratory has utilized isolated heart perfusions combined with nuclear magnetic resonance (NMR) spectroscopy to ... forming the basis of methods such as 2-deoxyglucose and functional magnetic resonance imaging. However, use of such methods in ... This cell death might not be accompanied by a reduction in tumor size as measured by physical means. The ability to see early ... This xenograft tumor model system is valuable for the pre-clinical in vivo evaluation of putative antitumor compounds. The 4T1 ...
  https://www.jove.com/visualize/abstract/24911170/bistability-glycolysis-pathway-as-physiological-switch-energy
*  Proton MR spectroscopy of the brain at 3 T: an update | SpringerLink
Proton magnetic resonance spectroscopy (1H-MRS) provides specific metabolic information not otherwise observable by any other ... Proton magnetic resonance spectroscopy of the brain of a neonate with nonketotic hyperglycinemia: in vivo-in vitro (ex vivo) ... These can manifest as a reduction in slice number per TR period, longer scanner time and "patient cooling" delays between ... operating at 3 T is taking structural and functional imaging to new levels and is reinvigorating clinical brain spectroscopy. ...
  https://link.springer.com/article/10.1007%2Fs00330-006-0546-1