*  List of recombinant proteins - Wikipedia
The prefix "rh" for "recombinant human" appears less and less in the literature. A much larger number of recombinant proteins ... In many cases, recombinant human proteins have replaced the original animal-derived version used in medicine. ... The following is a list of notable proteins that are generated from recombinant DNA, using biomolecular engineering, focusing ... Bovine Chymosin Envelope protein of the hepatitis B virus marketed as Engerix-B by SmithKline Beecham HPV Vaccine proteins ...
  https://en.wikipedia.org/wiki/List_of_recombinant_proteins
*  NGR-hTNF (antitumor recombinant protein) - Wikipedia
NGR-hTNF is a recombinant protein derived from the fusion between peptide CNGRCG and human tumor necrosis factor alpha (TNFα). ...
  https://en.wikipedia.org/wiki/NGR-hTNF_(antitumor_recombinant_protein)
*  Factor VIII (medication) - Wikipedia
Buckel, P. (2012). Recombinant Protein Drugs. Birkhäuser. p. 79. ISBN 9783034883467. Archived from the original on 2017-01-09. ... Recombinant factor VIII was first made in 1984 and approved for medical use in the United States in 1992. It is on the World ... A recombinant version is also available. People may develop antibodies to factor VIII such that this medication becomes less ... In the early 1990s, pharmaceutical companies began to produce recombinant synthesized factor products, which now prevent nearly ...
  https://en.wikipedia.org/wiki/Factor_VIII_(medication)
*  IFNB1 - Wikipedia
Interferon beta is a protein that in humans is encoded by the IFNB1 gene. The natural and recombinant protein forms have ... "IFNB1 recombinant protein". Biron CA, Nguyen KB, Pien GC (2002). "Innate immune responses to LCMV infections: natural killer ... 1982). "Secretory proteins induced in human fibroblasts under conditions used for the production of interferon beta". Proc. ... 1987). "Structure of the carbohydrate moiety of human interferon-beta secreted by a recombinant Chinese hamster ovary cell line ...
  https://en.wikipedia.org/wiki/IFNB1
*  TREX2 - Wikipedia
Characterization of the recombinant proteins". J. Biol. Chem. 276 (20): 17022-9. doi:10.1074/jbc.M100623200. PMID 11279105. ... 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. doi:10.1038 ... identification in a genetic screen and effects on catalysis by the recombinant proteins". Adv. Enzyme Regul. 44: 37-49. doi: ... Similarity to an E. coli protein suggests that this enzyme may be a subunit of DNA polymerase III, which does not have ...
  https://en.wikipedia.org/wiki/TREX2
*  Nesfatin-1 - Wikipedia
"Nesfatin-1 Recombinant Protein". Retrieved 21 March 2013. Pan, Weihong; Hsuchou, Hung; Kastin, Abba J. (2007). "Nesfatin-1 ... Nesfatin-1 is a polypeptide encoded in the N-terminal region of the protein precursor, Nucleobindin2 (NUCB2). Recombinant human ... In addition, the protein stimulated insulin secretion from the pancreatic beta cells of both rats and mice. ... It is needed to fully activate AKT and consists of two discrete protein complexes, TORC1 and TORC2, only one of which, TORC1, ...
  https://en.wikipedia.org/wiki/Nesfatin-1
*  Immunogenicity - Wikipedia
recombinant protein, or monoclonal antibody). This reaction leads to production of anti-drug-antibodies (ADAs) inactivating the ... Proteins or polysaccharides are used for studies of humoral immune response. Only proteins can serve as immunogens for cell- ... By calculating the density of high-scoring frames within a protein, it is possible to estimate a protein's overall " ... The prediction of the immunogenic potential of novel protein therapeutics is thus a challenge in biotherapy. Proteins are ...
  https://en.wikipedia.org/wiki/Immunogenicity
*  N-linked glycosylation - Wikipedia
Strasser R, Altmann F, Steinkellner H (December 2014). "Controlled glycosylation of plant-produced recombinant proteins". ... A chaperone protein (calnexin/calreticulin) binds to the unfolded or partially folded protein to assist protein folding. The ... The proteins produced in these expression hosts are often not identical to human protein and thus, causes immunogenic reactions ... This initial trimming step is thought to act as a quality control step in the ER to monitor protein folding. Once the protein ...
  https://en.wikipedia.org/wiki/N-linked_glycosylation
*  Thrombospondin 1 - Wikipedia
Characterization of these motifs has led to the use of recombinant proteins that contain these motifs; these recombinant ... This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to ... "Differential roles of protein kinase C and pertussis toxin-sensitive G-binding proteins in modulation of melanoma cell ... Bound protein fragments of the type I repeats have been shown to serve as attachment factors for both ECs and melanoma cells. ...
  https://en.wikipedia.org/wiki/Thrombospondin_1
*  Induced stem cells - Wikipedia
... using the genetic material encoding reprogramming protein factors, recombinant proteins; microRNA, a synthetic, self- ... "Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins". Cell Stem Cell. 4 (5): 381-4. doi:10.1016/j.stem. ... CCAAT/enhancer binding protein-α (C/EBPα) induces transdifferentiation of B cells into macrophages at high efficiencies and ... Cell adhesion protein E-cadherin is indispensable for a robust pluripotent phenotype. During reprogramming for iPS cell ...
  https://en.wikipedia.org/wiki/Induced_stem_cells
*  Induced pluripotent stem cell - Wikipedia
A non-genetic method of producing iPSCs has been demonstrated using recombinant proteins, but its efficiency was quite low. ... May 2009). "Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins". Cell Stem Cell. 4 (5): 381-4. doi:10.1016 ... LIN28: LIN28 is an mRNA binding protein expressed in embryonic stem cells and embryonic carcinoma cells associated with ... The acronym given for those iPSCs is piPSCs (protein-induced pluripotent stem cells). Another key strategy for avoiding ...
  https://en.wikipedia.org/wiki/Induced_pluripotent_stem_cell
*  Fed-batch culture - Wikipedia
Production of heterologous proteins by fed-batch cultures of recombinant microorganisms have been extensively studied. The ... Eds). Recombinant Protein Production with prokaryotic and eukaryotic cells. A comparative view on host physiology. 2001, Kluwer ... L. Yee, Harvey W. Blanch: Recombinant protein expression in high cell density fed-batch cultures of Escherichia coli. Bio/ ... Neubauer P, Winter J: Expression and fermentation strategies for recombinant protein production in Escherichia coli. In: Merten ...
  https://en.wikipedia.org/wiki/Fed-batch_culture
*  Genetically modified bacterium - Wikipedia
These recombinant proteins are safer than the products they replaced. Prior to recombinant protein products, several treatments ... Bryant J, Baxter L, Cave CB, Milne R (July 2007). "Recombinant growth hormone for idiopathic short stature in children and ... Baxter L, Bryant J, Cave CB, Milne R (January 2007). "Recombinant growth hormone for children and adolescents with Turner ... Pipe SW (May 2008). "Recombinant clotting factors". Thrombosis and Haemostasis. 99 (5): 840-50. doi:10.1160/TH07-10-0593. PMID ...
  https://en.wikipedia.org/wiki/Genetically_modified_bacterium
*  L-form bacteria - Wikipedia
These strains are being examined for possible uses in biotechnology as host strains for recombinant protein production. Here, ... Choi JH, Lee SY (June 2004). "Secretory and extracellular production of recombinant proteins using Escherichia coli". Appl. ... the absence of a cell wall can allow production of large amounts of secreted proteins that would otherwise accumulate in the ...
  https://en.wikipedia.org/wiki/L-form_bacteria
*  Elastin like polypeptides - Wikipedia
"Elastin-like polypeptides as a purification tag for recombinant proteins". Current Protocols in Protein Science. doi:10.1002/ ... ELPs can be engineered to recognize specific proteins in solution. The protein purification aspect of ELPs is supported by the ... In this linear state, the ELP-protein complex cannot easily be distinguished from the extraneous proteins in the solution. ... Tt is altered by the addition of unique proteins to the free ELPs. Tropoelastin is a protein, of size 72kDa, that comes ...
  https://en.wikipedia.org/wiki/Elastin_like_polypeptides
*  Ogataea polymorpha - Wikipedia
2005). Production of recombinant proteins - novel microbial and eukaryotic expression systems. Weinheim: Wiley-VCH. ISBN 3-527- ... Strains CBS4732 and DL-1 are employed for recombinant protein production, strain NCYC495 is mainly used for the study of ... They exhibit different features and are used in basic research and to recombinant protein production: strain CBS4732 (CCY38-22- ... O. polymorpha produces glycoproteins with two types of sugar chains, N- and O-linked glycans are attached to protein. Studies ...
  https://en.wikipedia.org/wiki/Ogataea_polymorpha
*  FlAsH-EDT2 - Wikipedia
Griffin, B. Albert; Adams, Stephen R.; Jones, Jay; Tsien, Roger Y. (2000). "Fluorescent labeling of recombinant proteins in ... from fluorescent proteins, such as from enhanced cyan fluorescent protein (ECFP) of Green Fluorescent Protein (GFP). FlAsH-EDT2 ... Griffin, B. Albert; Adams, Stephen R.; Tsien, Roger Y. (1998). "Specific Covalent Labeling of Recombinant Protein Molecules ... Ebola virus matrix protein, and protein misfolding. With the electron microscopic imaging, FlAsH-EDT2 is also used to study the ...
  https://en.wikipedia.org/wiki/FlAsH-EDT2
*  Pichia pastoris - Wikipedia
Pichia is widely used for protein production using recombinant DNA techniques. Hence it is used in biochemical and genetic ... As the protein yield from expression in a microbe is roughly equal to the product of the protein produced per cell and the ... These media significantly increase the cost of producing recombinant proteins. Additionally, since Pichia can grow in media ... Brondyk WH (2009). "Selecting an appropriate method for expressing a recombinant protein". Meth. Enzymol. Methods in Enzymology ...
  https://en.wikipedia.org/wiki/Pichia_pastoris
*  In vivo - Wikipedia
Compounds that bind to isolated recombinant proteins are one thing; chemical tools that can perturb cell function another; and ...
  https://en.wikipedia.org/wiki/In_vivo
*  Vaccine - Wikipedia
Recombinant proteins need many operations involving ultrafiltration and column chromatography. Finally, the vaccine is ... Egg protein is present in influenza and yellow fever vaccines as they are prepared using chicken eggs. Other proteins may be ... Some cells of the immune system that recognize the proteins expressed will mount an attack against these proteins and cells ... a recombinant protein derived from the viruses or bacteria can be generated in yeast, bacteria, or cell cultures. After the ...
  https://en.wikipedia.org/wiki/Vaccine
*  C8orf48 - Wikipedia
Recombinant Protein Collection". rProtein. Lupo A, Cesaro E, Montano G, Zurlo D, Izzo P, Costanzo P (2013). "KRAB-Zinc Finger ... The C8orf48 protein is predicted to be a nuclear protein particularly located in the nuclear lamina. This protein does not ... C8orf48 is a protein that in humans is encoded by the C8orf48 gene. C8orf48 is a nuclear protein specifically predicted to be ... The protein C8orf48 is 319 amino acids in length. The molecular weight of this protein is 36.9 kDa and the isoelectric point is ...
  https://en.wikipedia.org/wiki/C8orf48
*  Affimer - Wikipedia
Due to Affimer proteins being generated using recombinant systems, their generation is significantly more rapid and ... Affimer binders are recombinant proteins. They display the robust characteristics of high thermostability, with melting ... "ALS applications data - Protein-protein interactions". Kyle H.F.; Wickson K.F.; Stott J.; Burslem G.M.; Breeze A.L.; Tiede C.; ... "ALS application data protein-protein interactions". Fisher MJ, Williamson DJ, Burslem GM, Plante JP, Manfield IM, Tiede C, Ault ...
  https://en.wikipedia.org/wiki/Affimer
*  NS0 cell - Wikipedia
The GS-NS0 is a heterologous mammalian expression system that allows for the rapid expression of recombinant proteins. Several ... M. Barnes, Louise; Bentley, Catherine M.; Dickson, Alan J. (2000). "Advances in animal cell recombinant protein production: GS- ... Barnes, LM; Bentley, CM; Dickson, AJ (February 2000). "Advances in animal cell recombinant protein production: GS-NS0 ... Wurm, Florian M (November 2004). "Production of recombinant protein therapeutics in cultivated mammalian cells". Nature ...
  https://en.wikipedia.org/wiki/NS0_cell
*  Association of Biomolecular Resource Facilities - Wikipedia
Other: bioinformatics, carbohydrate analysis, differential display, recombinant protein production. Every year the Association ... Protein/Peptide Chemistry: amino acid analysis, N- and C-terminal sequencing, peptide synthesis, peptide/protein arrays. ... Protein Expression Research Group (PERG) Protein Sequencing Research Group (PSRG) Proteomics Research Group (PRG) Proteome ... The next year protein sequencing and amino acid samples were sent to survey 103 core facilities. By 1989 the ABRF was formally ...
  https://en.wikipedia.org/wiki/Association_of_Biomolecular_Resource_Facilities
*  Industrial fermentation - Wikipedia
Recombinant proteins, such as insulin, hepatitis B vaccine, interferon, granulocyte colony-stimulating factor, streptokinase ... Wurm FM (2004). "Production of recombinant protein therapeutics in cultivated mammalian cells". Nature Biotechnology. 22: 1393- ... Furthermore, the product (typically a protein) must be separated from all of the other cellular proteins in the lysate to be ... Examples include single cell protein, bakers yeast, lactobacillus, E. coli, and others. In the case of single-cell protein, ...
  https://en.wikipedia.org/wiki/Industrial_fermentation