*  RGS17 - Regulator of G-protein signaling 17 - Homo sapiens (Human) - RGS17 gene & protein
Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity). ... including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by ... Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity).By similarity. ,p>Manually ... The sumoylated forms act as a scaffold for sequestering mu-opioid receptor-activated G(alpha) subunits.By similarity. ,p> ...
  http://www.uniprot.org/uniprot/Q9UGC6
*  Mu Opioid Receptor抗体|Abcam中国|Anti-Mu Opioid Receptor抗体(ab10275)
Mu Opioid Receptor兔多克隆抗体(ab10275)可与小鼠, 大鼠, 豚鼠, 人样本反应并经WB, IHC, ICC, ICC/IF实验严格验证 ... Anti-Mu Opioid Receptor抗体. 参阅全部 Mu Opioid Receptor 一抗. ... Mu Opioid Receptor (ab10275) staining of Rat DRG (dilution: 1:100) incubation at 4 °C overnight. Secondary antibody is anti- ... Detects a band of approximately 49-65 kDa (predicted molecular weight: 45 kDa).Can
  http://www.abcam.cn/mu-opioid-receptor-antibody-ab10275.html
*  INT5501 - wiki-pain
With the availability of the cDNA clones of the mu-, delta- and kappa-opioid receptors, and the elucidation of their gene ... Spec (investigate) Regulation (regulation) of opioid receptor associated with kappa opioid receptor, opioid receptor and opioid ... Regulation (regulating) of opioid receptor associated with addiction, tolerance, opioid receptor and opioid ... Spec (analyzed) Regulation (regulation) of delta-opioid receptor mRNA in cerebral cortex associated with opioid receptor and ...
  http://gnteam.cs.manchester.ac.uk/demos/wiki-pain/vhosts/wikipaints/mediawiki-1.19.1/index.php/INT5501
*  AID 141501 - Tested for antagonist potency against mu opioid receptor using morphine ligand in guinea pig ileal longitudinal...
Tested for antagonist potency against mu opioid receptor using morphine ligand in guinea pig ileal longitudinal muscle at 100 ...
  https://pubchem.ncbi.nlm.nih.gov/bioassay/141501
*  The μ-Opioid Receptor in Cancer Progression:Is There a Direct Effect? | Anesthesiology | ASA Publications
Human mu opioid receptor (OPRM1 A118G) polymorphism is associated with brain mu-opioid receptor binding potential in smokers. ... The opioid receptors are members of the seven-transmembrane-spanning, G-protein-coupled receptor superfamily.16 Acute opioid ... There is evidence of a direct effect of μ-opioids on tumor progression or recurrence.7,11,14 Opioid receptors are divided into ... The novel role of the mu opioid receptor in lung cancer progression: A laboratory investigation. Anesth Analg 2011; 112:558-67 ...
  http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1933984
*  Morphine induces terminal μ‐opioid receptor desensitization by sustained phosphorylation of serine‐375 | The EMBO Journal
Alvarez VA, Arttamangkul S, Dang V, Salem A, Whistler JL, Von Zastrow M, Grandy DK, Williams JT (2002) muOpioid receptors: ... Yu Y, Zhang L, Yin X, Sun H, Uhl GR, Wang JB (1997) Mu opioid receptor phosphorylation, desensitization, and ligand efficacy. J ... Koch T, Schulz S, Schroder H, Wolf R, Raulf E, Hollt V (1998) Carboxyl‐terminal splicing of the rat mu opioid receptor ... Bailey CP, Couch D, Johnson E, Griffiths K, Kelly E, Henderson G (2003) Muopioid receptor desensitization in mature rat ...
  http://emboj.embopress.org/content/23/16/3282
*  Early-stage Drug Development - Cabernet Pharmaceuticals Inc.
Response to the opioid-receptor antagonist naltrexone, for example, is predicted by a genetic variant of the mu-opioid receptor ... Opioid-receptor antagonist. Endogenous opioid-mediated reward pathways play a role in the development and maintenance of ... Eli Lilly and Company, a Cabernet client, therefore sought to determine whether a brain opioid-receptor antagonist (LY2196044 ... CCK-A receptor agonist. While on staff at GlaxoSmithKline, scientists now at Cabernet integrated PGx into a Phase IIa/POC study ...
  https://cabernetpharma.com/early-stage-drug-development/
*  Enhancement of Morphine Analgesic Effect with Induction of μ-Opioid Receptor Endocytosis in Rats | Anesthesiology | ASA...
Synergy between mu opioid ligands: evidence for functional interactions among mu opioid receptor subtypes. J Pharmacol Exp Ther ... Peptidases prevent mu-opioid receptor internalization in dorsal horn neurons by endogenously released opioids. J Neurosci 2003 ... Zaki PA, Keith DE Jr, Brine GA, Carroll FI, Evans CJ: Ligand-induced changes in surface mu-opioid receptor number: Relationship ... Whistler JL, Chuang HH, Chu P, Jan LY, von Zastrow M: Functional dissociation of mu opioid receptor signaling and endocytosis: ...
  http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1931224
*  mu Opioid Receptors - mu Opioid Receptor Summary Report | CureHunter
A class of opioid receptors recognized by its pharmacological profile. Mu opioid receptors bind, in decreasing order of ... They have also been shown to be molecular receptors for morphine. ... Opioid, mu; Morphine Receptor; mu Receptor; Opioid Receptor, mu ... mu; Receptor, mu Opioid; Morphine Receptors; Opioid Receptors, mu; Receptors, Morphine; Receptors, mu; Receptors, mu Opioid; mu ... mu Opioid Receptors (mu Opioid Receptor). Subscribe to New Research on mu Opioid Receptors ...
  http://www.curehunter.com/public/keywordSummaryD017450-mu-Opioid-Receptors-mu-Opioid-Receptor.do
*  Mu opioid receptor (IPR000105) | InterPro | EMBL-EBI
Mu opioid receptor (IPR000105). Short name: Mu_opioid_rcpt Family relationships *G protein-coupled receptor, rhodopsin-like ( ... The term opioid refers to a class of substance that produces its effects via the major classes of opioid receptor, termed mu, ... Mu opioid receptors are believed to mediate analgesia, hypothermia, respiratory depression, miosis, bradycardia, nausea, ... In the CNS, the mu opioid receptor is found in the cerebral cortex, thalamus, hypothalamus, periaqueductal grey, ...
  http://www.ebi.ac.uk/interpro/entry/IPR000105
*  Chronic Pain Researchers First to Link Regulatory Protein to Mu Opioid Receptor Signaling
The MOR is the target of opioid drugs like morphine and is an important mechanism for pain regulation in the body. The research ... Researchers found initial confirmation that a novel scaffold protein previously unassociated with the mu opioid receptor (MOR) ... Poster 223 - Unbiased Screens for Novel Signaling Regulators of the Mu Opioid Receptor John Streicher, jstreicher@une.edu ... Chronic Pain Researchers First to Link Regulatory Protein to Mu Opioid Receptor Signaling. ...
  http://www.newswise.com/articles/view/614467/?sc=rsla
*  Designing Safer Analgesics via mu-Opioid Receptor Pathways - Infoscience
... especially those acting on the m-opioid receptor (mOR)and related pathways, have proven to be the most effective, despite some ... In this review we outline recent progress towards the discovery of safer opioid analgesics. Chan, H. C. Stephen; Mccarthy, ... While a variety of prescribed or over-the-counter (OTC) medications are available for pain management, opioid medications, ... It is therefore imperative that both academia and industry develop novel mOR analgesics which retain their opioid analgesic ...
  https://infoscience.epfl.ch/record/232193
*  JCI - Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine
Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine. ... Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine. ... Extensive 3′ alternative splicing of the mu opioid receptor gene OPRM1. creates multiple C-terminal splice variants. However, ... In cell-based studies, exon 7-associated variants shifted the bias of several mu opioids toward β-arrestin 2 over G protein ...
  https://www.jci.org/articles/view/88760/sd/1
*  JCI - Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine
... of an array of mu opioid receptor variants produced by alternative pre-mRNA splicing of the single-copy mu opioid receptor gene ... of opioid receptor variants.. Abstract. Extensive 3′ alternative splicing of the mu opioid receptor gene OPRM1 creates multiple ... Mu-opioid receptor desensitization: role of receptor phosphorylation, internalization, and representation. J Biol Chem. 2003; ... Mu opioid receptor agonist-induced desensitization involves many proteins in various cellular processes, such as receptor ...
  https://www.jci.org/articles/view/88760
*  Mu Opioid Receptor 1 ELISA & Assay Kits
Compare and order Mu Opioid Receptor 1 ELISA Kits. View citations, images, detection ranges, sensitivity, prices and more. ... mu opioid receptor splice variant rMOR-1Z , opioid receptor B , ZfMOR , opioid receptor, mu 1 , mu opioid receptor , mu-opioid ... mu opiate receptor , mu opioid receptor hMOR-1a , mu-type opioid receptor , MOP receptor , M-OR-1 , MOR-1 , MUOR1 , mu opioid ... Mu Opioid Receptor 1 Antigen Profile Antigen Summary This gene encodes one of three opioid receptors. The mu opioid receptor is ...
  https://www.antibodies-online.com/camp-metabolic-process-pathway-59/mu-opioid-receptor-1-elisa-kit-10459/
*  AID 151007 - % stimulation of GTPgammaS binding in cloned human Opioid receptor mu 1 transfected into hamster ovary cells with...
... stimulation of GTPgammaS binding in cloned human Opioid receptor mu 1 transfected into hamster ovary cells with respect to ...
  https://pubchem.ncbi.nlm.nih.gov/bioassay/151007
*  Vimentin interacts with the 5'-untranslated region of mouse mu opioid receptor (MOR) and is required for post-transcriptional...
Morphine and endogenous mu opioid peptides exert their pharmacological actions mainly through the mu opioid receptor (MOR). ... Vimentin interacts with the 5'-untranslated region of mouse mu opioid receptor (MOR) and is required for post-transcriptional ... Vimentin interacts with the 5′-untranslated region of mouse mu opioid receptor (MOR) and is required for post-transcriptional ... Vimentin interacts with the 5′-untranslated region of mouse mu opioid receptor (MOR) and is required for post-transcriptional ...
  https://www.ncbi.nlm.nih.gov/pubmed/23353576
*  Anti-Human Mu Opioid Receptor 1 antibody for Immunofluorescence (Paraffin-embedded Sections) (IF (p))
... find the top performing anti-Human Mu Opioid Receptor 1 antibody for Immunofluorescence (Paraffin-embedded Sections) (IF (p)). ... mu Opioid Receptor (OPRM1 Antibody Abstract) Background This gene encodes one of three opioid receptors. The mu opioid receptor ... Product Details anti-Mu Opioid Receptor 1 Antibody Target Details Mu Opioid Receptor 1 Handling References for anti-Mu Opioid ... Product Details anti-Mu Opioid Receptor 1 Antibody Target Details Mu Opioid Receptor 1 Application Details Handling Images back ...
  http://www.antibodies-online.com/tcr-signaling-pathway-12/mu-opioid-receptor-1-antibody-4483/human-if-p-21946/
*  The Mu Opioid Receptor Genotype May be a Marker for Those Who Drink for Alcohol's Rewarding Effects, University of California,...
The Mu Opioid Receptor Genotype May be a Marker for Those Who Drink for Alcohol's Rewarding Effects, University of California, ... The Mu Opioid Receptor Genotype May be a Marker for Those Who Drink for Alcohol's Rewarding Effects, University of California, ... The A118G single nucleotide polymorphism (SNP) of the mu opioid receptor (OPRM1) gene had also been previously associated with ...
  https://www.biospace.com/article/the-mu-opioid-receptor-genotype-may-be-a-marker-for-those-who-drink-for-alcohol-s-rewarding-effects-university-of-california-los-angeles-ucla-stud/
*  Inhibitory actions of delta 1-, delta 2-, and mu-opioid receptor agonists on excitatory transmission in lamina II neurons of...
Inhibitory actions of delta 1-, delta 2-, and mu-opioid receptor agonists on excitatory transmission in lamina II neurons of ... Inhibitory actions of delta 1-, delta 2-, and mu-opioid receptor agonists on excitatory transmission in lamina II neurons of ... Inhibitory actions of delta 1-, delta 2-, and mu-opioid receptor agonists on excitatory transmission in lamina II neurons of ... Inhibitory actions of delta 1-, delta 2-, and mu-opioid receptor agonists on excitatory transmission in lamina II neurons of ...
  http://www.jneurosci.org/content/14/8/4965