Staff List - NUI Galway
Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients' Glynn SA, Boersma BJ, Dorsey TH, Yi ... S-Nitrosation Mediates Multiple Pathways That Lead to Tumor Progression in Estrogen Receptor-Negative Breast Cancer' Switzer CH ... Ets-1 is a transcriptional mediator of oncogenic nitric oxide signaling in estrogen receptor-negative breast cancer' Switzer, ... NOS2&COX2 ACTIVATION OF TLR4 AND EGFR SIGNALLING CAUSES POOR OUTCOME IN OESTROGEN RECEPTOR-NEGATIVE BREAST CANCER VIA PRO ...http://www.nuigalway.ie/medicine-nursing-and-health-sciences/medicine/disciplines/medicine/stafflist/sharonglynn/
Metronomic Schedule of Paclitaxel Is Effective in Hormone Receptor-Positive and Hormone Receptor-Negative Breast Cancer | Medic...
... hormone receptor-positive (estrogen receptor-positiveand/or progesterone receptor-positive and either HER2-positiveand/or ... Metronomic Schedule of Paclitaxel Is Effective in Hormone Receptor-Positive and Hormone Receptor-Negative Breast Cancer. ... Home » Metronomic Schedule of Paclitaxel Is Effective in Hormone Receptor-Positive and Hormone Receptor-Negative Breast Cancer ... It islikely that the small subgroup of patients with hormone receptor-positive breast cancer with low Ki-67 proliferation index ...http://medicdebate.org/node/391
IMPAKT 2013 Press Release: Genetic and clinical factors best for predicting late recurrence in oestrogen receptor positive...
In oestrogen-receptor positive women, half of all recurrences of breast cancer will occur after the women finish the standard 5 ... Background: Adjuvant endocrine therapy beyond 5 years is may be of benefit to some oestrogen receptor positive (ER+) patients, ... COMPARISON OF FIVE DIFFERENT SCORES FOR THE PREDICTION OF LATE RECURRENCE FOR OESTROGEN RECEPTOR POSITIVE BREAST CANCER. I. ... A new analysis has provided a comprehensive comparison of scores designed to predict which women with oestrogen-receptor ...http://www.esmo.org/Topics/Breast-cancer/Genetic-and-clinical-factors-best-for-predicting-late-recurrence-in-oestrogen-receptor-positive-breast-cancer
Calcitriol restores antiestrogen responsiveness in estrogen receptor negative breast cancer cells: A potential new therapeutic...
Immunocytochemical determination of estrogen receptor, progesterone receptor, and 1,25-dihydroxyvitamin D3 receptor in breast ... Growth regulation of estrogen receptor-negative breast cancer cells transfected with complementary DNAs for estrogen receptor. ... Modulation of vitamin D receptor and estrogen receptor by 1,25(OH)2-vitamin D3 in T-47D human breast cancer cells. J Steroid ... 25-Dihydroxyvitamin D3 down-regulates estrogen receptor abundance and suppresses estrogen actions in MCF-7 human breast cancer ...https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-14-230
Z-Endoxifen Hydrochloride in Treating Patients With Metastatic or Locally Recurrent Estrogen Receptor-Positive Breast Cancer -...
Estrogen Receptor Positive HER2/Neu Positive Hot Flashes Recurrent Breast Carcinoma Stage IIIC Breast Cancer AJCC v7 Stage IV ... progesterone receptor (PR), steroid receptor co-activator (SRC)1, SRC3, as well as the insulin-like growth factor receptor (IGF ... Z-Endoxifen Hydrochloride in Treating Patients With Metastatic or Locally Recurrent Estrogen Receptor-Positive Breast Cancer. ... To determine the frequency of estrogen receptor 1 (ESR1) mutations and the presence of antitumor activity (response rate and ...https://clinicaltrials.gov/ct2/show/NCT01327781
Back to the Dead | Science Signaling
Treating estrogen receptor α (ERα)-negative tumor cells with Wnt-5a restores ERα and renders them susceptible to tamoxifen- ... Treating estrogen receptor α (ERα)-negative tumor cells with Wnt-5a restores ERα and renders them susceptible to tamoxifen- ... It binds to estrogen receptor α (ERα), decreasing the expression of ERα target genes, reducing cell proliferation, and inducing ... C. E. Ford, E. J. Ekström, T. Andersson, Wnt-5a signaling restores tamoxifen sensitivity in estrogen receptor-negative breast ...http://stke.sciencemag.org/content/2/62/ec94
A Phase Ib/II Study of Palbociclib in Combination With Bazedoxifene in Hormone Receptor Positive Breast Cancer - AdisInsight
A Phase Ib/II Study of Palbociclib in Combination With Bazedoxifene in Hormone Receptor Positive Breast Cancer Next Previous ... A Phase Ib/II Study of Palbociclib in Combination With Bazedoxifene in Hormone Receptor Positive Breast Cancer Recruiting ...http://adisinsight.springer.com/trials/700257174?error=cookies_not_supported&code=3d350c0b-71fc-4a6e-991f-afc2521705b5
Estrogens Block p53 in Breast Cancer | Science Signaling
In estrogen receptor-dependent breast cancer cells, estrogen signaling antagonizes the proapoptotic function of the tumor ... In estrogen receptor-dependent breast cancer cells, estrogen signaling antagonizes the proapoptotic function of the tumor ... Most breast cancers are associated with aberrant signaling by the estrogen receptor (ER), a nuclear hormone receptor and ... S. T. Bailey, H. Shin, T. Westerling, X. S. Liu, M. Brown, Estrogen receptor prevents p53-dependent apoptosis in breast cancer ...http://stke.sciencemag.org/content/5/249/ec284
Estrogen receptor/progesterone receptor/human epidermal growth factor receptor 2 status. Staining for estrogen receptor, ... Interestingly, in estrogen receptor-negative compared with estrogen receptor-positive; progesterone receptor-negative compared ... We have initiated a window trial of SAHA in both estrogen receptor-positive and estrogen receptor-negative DCIS in which ... Estrogen receptor-negative or progesterone receptor-negative cases in which ,1% of cells were stained could be scored ,1 by H- ...http://clincancerres.aacrjournals.org/content/15/9/3163
"Estrogen receptor alpha-negative and progesterone receptor-positive br" by Jawad Kiani, Afrasyab Khan et al.
... recognized immunohistochemical method employing monoclonal antibodies against estrogen and progesterone receptors was used. ... alpha subtype and progesterone receptor (PR) profile of breast carcinomas amongst 1625 cases over 2.5 years was carried out. ... The frequency of lymph node metastases was independent of receptor profile. In conclusion, our study group does exhibit ... Estrogen receptor alpha-negative and progesterone receptor-positive breast cancer: lab error or real entity? ...https://ecommons.aku.edu/pakistan_fhs_mc_pathol_microbiol/226/
Reportstack: The largest online library of market research reports: Detailed Study of the Estrogen Receptor Positive (ER+)...
In case of Estrogen Receptor Positive (ER+) Breast Cancer, Hormone therapy is the main focus of treatment after surgery and ... Coverage of the Estrogen Receptor Positive (ER+) Breast Cancer Phase III and Pre-registration Drugs Analysis by product type, ... Estrogen Receptor Positive (ER+) Breast Cancer - Treatment Landscape & Competitive Analysis, 2017 is a new market research ... Report Highlights:• The new report, provides a Estrogen Receptor Positive (ER+) Breast Cancer Treatment Landscape across the ...http://reportstack.blogspot.in/2017/05/detailed-study-of-estrogen-receptor.html
Fulvestrant and/or Anastrozole in Treating Postmenopausal Patients With Stage II-III Breast Cancer Undergoing Surgery - Full...
Estrogen Receptor Antagonists. Estrogen Antagonists. Hormone Antagonists. Hormones, Hormone Substitutes, and Hormone ... Estrogen Receptor-positive Breast Cancer HER2-negative Breast Cancer Invasive Ductal Breast Carcinoma Invasive Lobular Breast ... Tumor estrogen receptor (ER) Allred score between 0-5 or HER2 positive by IHC (3+) or amplified by FISH , 2.0. ... Fulvestrant inhibits tumor cell growth by reducing the levels of estrogen receptor in the tumor cell. It is not approved by the ...https://clinicaltrials.gov/ct2/show/NCT01953588
Lapatinib Terminated Phase 1 Trials for Estrogen Receptor Positive / Stage IV Breast Cancer / Estrogen Receptor Negative / HER2...
Lapatinib Terminated Phase 1 Trials for Estrogen Receptor Positive / Stage IV Breast Cancer / Estrogen Receptor Negative / HER2 ... Positive / Recurrent Breast Carcinoma / Progesterone Receptor Positive / Progesterone Receptor Negative Treatment. Back to ... DBCOND0031389 (Estrogen Receptor Positive). *DBCOND0028550 (Stage IV Breast Cancer). *DBCOND0036417 (Estrogen Receptor Negative ...https://www.drugbank.ca/drugs/DB01259/clinical_trials?conditions=DBCOND0036417%2CDBCOND0031389%2CDBCOND0037939%2CDBCOND0038639%2CDBCOND0031390%2CDBCOND0030216%2CDBCOND0028550&phase=1&purpose=treatment&status=terminated
New and emerging treatments for estrogen receptor-positive breast canc | TCRM
Hormone resistance is associated with a complex interaction of the estrogen receptor with growth factors, transmembrane ... estrogen receptor-positive breast cancer, hormone resistance, mammalian target of rapamycin, inhibition ... epidermal growth factor receptor, insulin-like growth factor-1 receptor, and the mammalian target of rapamycin pathway may act ... Everolimus is currently approved for combination with exemestane in postmenopausal women with advanced hormone receptor- ...https://www.dovepress.com/new-and-emerging-treatments-for-estrogen-receptor-positive-breast-canc-peer-reviewed-article-TCRM
... Charolyn Babichuk Charolyn_Babichuk at darwin.biochem.ualberta.ca Fri Jul 8 16:04:37 EST 1994 *Previous ... I am looking for an anti-human estrogen receptor antibody. Any information regarding commercially available (or personal) ...http://www.bio.net/bionet/mm/methods/1994-July/016074.html
Estrogen receptor negative breast cancers | OncoLink
Does breast cancer run along some continuum from estrogen-receptor positive to estrogen-receptor negative tumors? Are ER+ ... Hormone Receptors Explained HRT for Breast Cancer Survivors Tamoxifen Therapy for Estrogen Receptor Negative Breast Cancer ... If you have an ER- cancer: strategies to increase or decrease estrogen levels will have no bearing on your recurrence risk. You ... Treatment after lumpectomy in small estrogen negative tumors Tamoxifen after total hysterectomy and ovary removal Aromatase ...https://www.oncolink.org/frequently-asked-questions/cancers/breast/estrogen-receptor-negative-breast-cancers
Estrogen Receptor Positive - DrugBank
This project is supported by the Canadian Institutes of Health Research (award #111062), Alberta Innovates - Health Solutions, and by The Metabolomics Innovation Centre (TMIC), a nationally-funded research and core facility that supports a wide range of cutting-edge metabolomic studies. TMIC is funded by Genome Alberta, Genome British Columbia, and Genome Canada, a not-for-profit organization that is leading Canada's national genomics strategy with funding from the federal government. Maintenance, support, and commercial licensing is provided by OMx Personal Health Analytics, Inc. Designed by Educe Design & Innovation Inc. ...https://www.drugbank.ca/indications/DBCOND0031389
Phys.org - estrogen receptor
Estrogen receptor. Estrogen receptor refers to a group of receptors that are activated by the hormone 17β-estradiol (estrogen ... This article refers to the nuclear hormone receptor ER.. The main function of the estrogen receptor is as a DNA binding ... Two types of estrogen receptor exist: ER which is a member of the nuclear hormone family of intracellular receptors and the ... However, the estrogen receptor has additional functions independent of DNA binding.. This text uses material from Wikipedia, ...https://phys.org/tags/estrogen+receptor/
Estrogen Receptor Positive - Medical Dictionary / Glossary | Medindia
Estrogen Receptor Positive' - ER+. Breast cancer cells that have a protein (receptor molecule) to which estrogen will attach. ... Breast cancer cells that are ER+ need the hormone estrogen to grow and will usually respond to hormone (antiestrogen) therapy ... that blocks these receptor sites, is clearly explained in Medindia s glossary of medical terms ... Estrogen Receptor Positive. Ans : ER+. Breast cancer cells that have a protein (receptor molecule) to which estrogen will ...https://www.medindia.net/glossary/estrogen_receptor_positive.htm
DailyMed - Search Results for Estrogen Receptor Agonists
Anti-Estrogen Receptor alpha antibody (ab118847) | Abcam
Rabbit polyclonal Estrogen Receptor alpha antibody validated for WB, IHC and tested in Human and Mouse. Immunogen corresponding ... Anti-Estrogen Receptor alpha antibody. See all Estrogen Receptor alpha primary antibodies. ... Synthetic peptide within Human Estrogen Receptor alpha conjugated to keyhole limpet haemocyanin. The exact sequence is ... Immunohistochemical analysis of formalin-fixed, paraffin-embedded human breast tissue, staining Estrogen Receptor alpha with ...http://www.abcam.com/estrogen-receptor-alpha-antibody-ab118847.html
Anti-Estrogen Receptor beta antibody (ab3576) | Abcam
Rabbit polyclonal Estrogen Receptor beta antibody validated for WB, IHC, ICC, Inhibition, ICC/IF and tested in Human, Mouse and ... Anti-Estrogen Receptor beta antibody. See all Estrogen Receptor beta primary antibodies. ... Immunofluorescent analysis using Estrogen Receptor beta polyclonal antibody (ab3576) shows nuclear localization of Estrogen ... All lanes : Anti-Estrogen Receptor beta antibody (ab3576) at 1/2000 dilution. Lane 1 : CAL region of Human brain - Whole cell ...http://www.abcam.com/estrogen-receptor-beta-antibody-ab3576.html
Anti-Estrogen Receptor alpha antibody (ab3575) | Abcam
Rabbit polyclonal Estrogen Receptor alpha antibody validated for WB, IHC, ICC, Flow Cyt, ICC/IF and tested in Human, Mouse and ... Anti-Estrogen Receptor alpha antibody. See all Estrogen Receptor alpha primary antibodies. ... Anti-Estrogen Receptor alpha antibody (ab3575) at 1/1000 dilution. Lane 1 : Recombinant full-length human Estrogen Receptor ... Recombinant full-length human Estrogen Receptor alpha protein, 125 ng. Lane 3 : Recombinant full-length human Estrogen Receptor ...http://www.abcam.com/estrogen-receptor-alpha-antibody-ab3575.html
The Estrogen Receptor | Clinical Cancer Research
C Silencing and reactivation of the selective estrogen receptor modulator-estrogen receptor α complex. Cancer Res., 61: 3632- ... estrogen receptor; DMBA, 7,12-dimethylbenz(a)anthracene; SERM, selective estrogen receptor modulator. ... Jordan V. C. Antiestrogens and selective estrogen receptor modulators as multifunctional medicines part I: receptor ... and antiestrogen-estrogen receptor complexes from human breast tumors identified with an antibody raised against the estrogen ...http://clincancerres.aacrjournals.org/content/9/6/1980
Estrogen Receptor Research Products: Novus Biologicals
Browse our Estrogen Receptor product catalog backed by our Guarantee+. ... Estrogen Receptor alpha is a 65 kDa protein and a member of the steroid family of nuclear receptors. Estrogen Receptor alpha is ... Like other steroid hormone receptors, Estrogen Receptors are intracellular proteins. Estrogen Receptors play an important role ... Related Estrogen Receptor Blog Posts. Check out the latest blog posts on Estrogen Receptor. Cytokeratin 18 - A Intermediate ...https://www.novusbio.com/common-name/estrogen-receptor
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