DiVA - Sökresultat
In paper III we evaluated the role of mutations in the androgen receptor in the cohort of estrogen receptor-negative and ... We show that the most potent estrogen estradiol, in an estrogen receptor dependent fashion, can result in decreased ... We show that in patients with estrogen receptor negative tumors, the androgen receptor is associated with worse outcome. In ... despite lack of the estrogen receptor. The opposite was observed in patients without tumoral androgen receptor expression, and ...http://www.diva-portal.org/smash/resultList.jsf?faces-redirect=true&language=sv&searchType=SUBJECT&query=&af=%5B%5D&aq=%5B%5B%7B%22categoryId%22%3A%2211722%22%7D%5D%5D&aq2=%5B%5B%5D%5D&aqe=%5B%5D&noOfRows=50&sortOrder=author_sort_asc&sortOrder2=title_sort_asc&onlyFullText=false&sf=all
IMPAKT 2013 Press Release: Genetic and clinical factors best for predicting late recurrence in oestrogen receptor positive...
In oestrogen-receptor positive women, half of all recurrences of breast cancer will occur after the women finish the standard 5 ... Background: Adjuvant endocrine therapy beyond 5 years is may be of benefit to some oestrogen receptor positive (ER+) patients, ... COMPARISON OF FIVE DIFFERENT SCORES FOR THE PREDICTION OF LATE RECURRENCE FOR OESTROGEN RECEPTOR POSITIVE BREAST CANCER. I. ... A new analysis has provided a comprehensive comparison of scores designed to predict which women with oestrogen-receptor ...http://www.esmo.org/Topics/Breast-cancer/Genetic-and-clinical-factors-best-for-predicting-late-recurrence-in-oestrogen-receptor-positive-breast-cancer
Calcitriol restores antiestrogen responsiveness in estrogen receptor negative breast cancer cells: A potential new therapeutic...
Immunocytochemical determination of estrogen receptor, progesterone receptor, and 1,25-dihydroxyvitamin D3 receptor in breast ... Growth regulation of estrogen receptor-negative breast cancer cells transfected with complementary DNAs for estrogen receptor. ... Modulation of vitamin D receptor and estrogen receptor by 1,25(OH)2-vitamin D3 in T-47D human breast cancer cells. J Steroid ... 25-Dihydroxyvitamin D3 down-regulates estrogen receptor abundance and suppresses estrogen actions in MCF-7 human breast cancer ...https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-14-230
CRT unveils 'screen test ' for potential drugs to treat oestrogen positive breast cancer - Healthcanal.com : Healthcanal.com
Oestrogen receptor positive breast cancer.. The cancer cells contain oestrogen receptors. Oestrogen can attach to the receptors ... Current standard hormone treatments block the oestrogen receptor or the production of oestrogen. But sometimes patients stop ... Resistant ER-positive breast tumours often rely on cell signals triggered by the oestrogen receptor to continue to fuel the ... The discovery of molecules that block the FOXA1 pathway, which prevents the oestrogen receptor driving the cancer, might ...https://www.healthcanal.com/cancers/27232-crt-unveils-screen-test-for-potential-drugs-to-treat-oestrogen-positive-breast-cancer.html
Back to the Dead | Science Signaling
Treating estrogen receptor α (ERα)-negative tumor cells with Wnt-5a restores ERα and renders them susceptible to tamoxifen- ... Treating estrogen receptor α (ERα)-negative tumor cells with Wnt-5a restores ERα and renders them susceptible to tamoxifen- ... It binds to estrogen receptor α (ERα), decreasing the expression of ERα target genes, reducing cell proliferation, and inducing ... C. E. Ford, E. J. Ekström, T. Andersson, Wnt-5a signaling restores tamoxifen sensitivity in estrogen receptor-negative breast ...http://stke.sciencemag.org/content/2/62/ec94
Differential and Opposing Regulation of PAI-1 Promoter Activity by Estrogen Receptor α and Estrogen Receptor β in Endothelial...
Differential and Opposing Regulation of PAI-1 Promoter Activity by Estrogen Receptor α and Estrogen Receptor β in Endothelial ... Differential and Opposing Regulation of PAI-1 Promoter Activity by Estrogen Receptor α and Estrogen Receptor β in Endothelial ... Differential and Opposing Regulation of PAI-1 Promoter Activity by Estrogen Receptor α and Estrogen Receptor β in Endothelial ... Differential and Opposing Regulation of PAI-1 Promoter Activity by Estrogen Receptor α and Estrogen Receptor β in Endothelial ...http://circres.ahajournals.org/content/95/3/269
A Phase Ib/II Study of Palbociclib in Combination With Bazedoxifene in Hormone Receptor Positive Breast Cancer - AdisInsight
A Phase Ib/II Study of Palbociclib in Combination With Bazedoxifene in Hormone Receptor Positive Breast Cancer Next Previous ... A Phase Ib/II Study of Palbociclib in Combination With Bazedoxifene in Hormone Receptor Positive Breast Cancer Recruiting ...http://adisinsight.springer.com/trials/700257174?error=cookies_not_supported&code=3d350c0b-71fc-4a6e-991f-afc2521705b5
MBC - Page 3 - Cancer Commons
... estrogen, estrogen receptor, fulvestrant, Ibrance, immunotherapy, letrozole, MBC, metastatic breast cancer, palbociclib, ... The estrogen receptor (ER) protein is a treatment target not only because "it is there," but mainly because it drives tumor ... Tags: aromatase inhibitors, breast cancer, clinical trial, clinical trial results, ER, ER-positive, estrogen receptor, HER2, ... The name reflects the fact that cells of these cancers express estrogen receptors (ERs), which are protein features targeted by ...https://www.cancercommons.org/tag/mbc/page/3/
"Estrogen receptor alpha-negative and progesterone receptor-positive br" by Jawad Kiani, Afrasyab Khan et al.
... recognized immunohistochemical method employing monoclonal antibodies against estrogen and progesterone receptors was used. ... alpha subtype and progesterone receptor (PR) profile of breast carcinomas amongst 1625 cases over 2.5 years was carried out. ... The frequency of lymph node metastases was independent of receptor profile. In conclusion, our study group does exhibit ... Estrogen receptor alpha-negative and progesterone receptor-positive breast cancer: lab error or real entity? ...https://ecommons.aku.edu/pakistan_fhs_mc_pathol_microbiol/226/
Reportstack: The largest online library of market research reports: Detailed Study of the Estrogen Receptor Positive (ER+)...
In case of Estrogen Receptor Positive (ER+) Breast Cancer, Hormone therapy is the main focus of treatment after surgery and ... Coverage of the Estrogen Receptor Positive (ER+) Breast Cancer Phase III and Pre-registration Drugs Analysis by product type, ... Estrogen Receptor Positive (ER+) Breast Cancer - Treatment Landscape & Competitive Analysis, 2017 is a new market research ... Report Highlights:• The new report, provides a Estrogen Receptor Positive (ER+) Breast Cancer Treatment Landscape across the ...http://reportstack.blogspot.in/2017/05/detailed-study-of-estrogen-receptor.html
Fulvestrant and/or Anastrozole in Treating Postmenopausal Patients With Stage II-III Breast Cancer Undergoing Surgery - Full...
Estrogen Receptor Antagonists. Estrogen Antagonists. Hormone Antagonists. Hormones, Hormone Substitutes, and Hormone ... Estrogen Receptor-positive Breast Cancer HER2-negative Breast Cancer Invasive Ductal Breast Carcinoma Invasive Lobular Breast ... Tumor estrogen receptor (ER) Allred score between 0-5 or HER2 positive by IHC (3+) or amplified by FISH , 2.0. ... Fulvestrant inhibits tumor cell growth by reducing the levels of estrogen receptor in the tumor cell. It is not approved by the ...https://clinicaltrials.gov/ct2/show/NCT01953588
New and emerging treatments for estrogen receptor-positive breast canc | TCRM
Hormone resistance is associated with a complex interaction of the estrogen receptor with growth factors, transmembrane ... estrogen receptor-positive breast cancer, hormone resistance, mammalian target of rapamycin, inhibition ... epidermal growth factor receptor, insulin-like growth factor-1 receptor, and the mammalian target of rapamycin pathway may act ... Everolimus is currently approved for combination with exemestane in postmenopausal women with advanced hormone receptor- ...https://www.dovepress.com/new-and-emerging-treatments-for-estrogen-receptor-positive-breast-canc-peer-reviewed-article-TCRM
Characterization of the estrogen receptor and its dynamics in MCF-7 human breast cancer cells using a covalently attaching...
Affinity labeled receptor interacts with several monoclonal antibodies to MCF-7 estrogen receptor, and it can be purified ... The labeling of receptor with (/sup 3/H)TA is specific, being blocked only by estrogens and antiestrogens, and the labeling is ... 59 BASIC BIOLOGICAL SCIENCES; RECEPTORS; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; ESTROGENS; MAMMARY GLANDS; MONOCLONAL ... Title: Characterization of the estrogen receptor and its dynamics in MCF-7 human breast cancer cells using a covalently ...https://www.osti.gov/scitech/biblio/6472430
... Charolyn Babichuk Charolyn_Babichuk at darwin.biochem.ualberta.ca Fri Jul 8 16:04:37 EST 1994 *Previous ... I am looking for an anti-human estrogen receptor antibody. Any information regarding commercially available (or personal) ...http://www.bio.net/bionet/mm/methods/1994-July/016074.html
Estrogen receptor negative breast cancers | OncoLink
Does breast cancer run along some continuum from estrogen-receptor positive to estrogen-receptor negative tumors? Are ER+ ... Hormone Receptors Explained HRT for Breast Cancer Survivors Tamoxifen Therapy for Estrogen Receptor Negative Breast Cancer ... If you have an ER- cancer: strategies to increase or decrease estrogen levels will have no bearing on your recurrence risk. You ... Treatment after lumpectomy in small estrogen negative tumors Tamoxifen after total hysterectomy and ovary removal Aromatase ...https://www.oncolink.org/frequently-asked-questions/cancers/breast/estrogen-receptor-negative-breast-cancers
Estrogen Receptor Positive - DrugBank
This project is supported by the Canadian Institutes of Health Research (award #111062), Alberta Innovates - Health Solutions, and by The Metabolomics Innovation Centre (TMIC), a nationally-funded research and core facility that supports a wide range of cutting-edge metabolomic studies. TMIC is funded by Genome Alberta, Genome British Columbia, and Genome Canada, a not-for-profit organization that is leading Canada's national genomics strategy with funding from the federal government. Maintenance, support, and commercial licensing is provided by OMx Personal Health Analytics, Inc. Designed by Educe Design & Innovation Inc. ...https://www.drugbank.ca/indications/DBCOND0031389
Phys.org - estrogen receptor
Estrogen receptor. Estrogen receptor refers to a group of receptors that are activated by the hormone 17β-estradiol (estrogen ... This article refers to the nuclear hormone receptor ER.. The main function of the estrogen receptor is as a DNA binding ... Two types of estrogen receptor exist: ER which is a member of the nuclear hormone family of intracellular receptors and the ... However, the estrogen receptor has additional functions independent of DNA binding.. This text uses material from Wikipedia, ...https://phys.org/tags/estrogen+receptor/
Estrogen Receptor Positive - Medical Dictionary / Glossary | Medindia
Estrogen Receptor Positive' - ER+. Breast cancer cells that have a protein (receptor molecule) to which estrogen will attach. ... Breast cancer cells that are ER+ need the hormone estrogen to grow and will usually respond to hormone (antiestrogen) therapy ... that blocks these receptor sites, is clearly explained in Medindia s glossary of medical terms ... Estrogen Receptor Positive. Ans : ER+. Breast cancer cells that have a protein (receptor molecule) to which estrogen will ...https://www.medindia.net/glossary/estrogen_receptor_positive.htm
DailyMed - Search Results for Estrogen Receptor Agonists
Anti-Estrogen Receptor alpha antibody (ab118847) | Abcam
Rabbit polyclonal Estrogen Receptor alpha antibody validated for WB, IHC and tested in Human and Mouse. Immunogen corresponding ... Anti-Estrogen Receptor alpha antibody. See all Estrogen Receptor alpha primary antibodies. ... Synthetic peptide within Human Estrogen Receptor alpha conjugated to keyhole limpet haemocyanin. The exact sequence is ... Immunohistochemical analysis of formalin-fixed, paraffin-embedded human breast tissue, staining Estrogen Receptor alpha with ...http://www.abcam.com/estrogen-receptor-alpha-antibody-ab118847.html
Anti-Estrogen Receptor beta antibody (ab3576) | Abcam
Rabbit polyclonal Estrogen Receptor beta antibody validated for WB, IHC, ICC, Inhibition, ICC/IF and tested in Human, Mouse and ... Anti-Estrogen Receptor beta antibody. See all Estrogen Receptor beta primary antibodies. ... Immunofluorescent analysis using Estrogen Receptor beta polyclonal antibody (ab3576) shows nuclear localization of Estrogen ... All lanes : Anti-Estrogen Receptor beta antibody (ab3576) at 1/2000 dilution. Lane 1 : CAL region of Human brain - Whole cell ...http://www.abcam.com/estrogen-receptor-beta-antibody-ab3576.html
Anti-Estrogen Receptor alpha antibody (ab3575) | Abcam
Rabbit polyclonal Estrogen Receptor alpha antibody validated for WB, IHC, ICC, Flow Cyt, ICC/IF and tested in Human, Mouse and ... Anti-Estrogen Receptor alpha antibody. See all Estrogen Receptor alpha primary antibodies. ... Anti-Estrogen Receptor alpha antibody (ab3575) at 1/1000 dilution. Lane 1 : Recombinant full-length human Estrogen Receptor ... Recombinant full-length human Estrogen Receptor alpha protein, 125 ng. Lane 3 : Recombinant full-length human Estrogen Receptor ...http://www.abcam.com/estrogen-receptor-alpha-antibody-ab3575.html
The Estrogen Receptor | Clinical Cancer Research
C Silencing and reactivation of the selective estrogen receptor modulator-estrogen receptor α complex. Cancer Res., 61: 3632- ... estrogen receptor; DMBA, 7,12-dimethylbenz(a)anthracene; SERM, selective estrogen receptor modulator. ... Jordan V. C. Antiestrogens and selective estrogen receptor modulators as multifunctional medicines part I: receptor ... and antiestrogen-estrogen receptor complexes from human breast tumors identified with an antibody raised against the estrogen ...http://clincancerres.aacrjournals.org/content/9/6/1980
Estrogen Receptor Research Products: Novus Biologicals
Browse our Estrogen Receptor product catalog backed by our Guarantee+. ... Estrogen Receptor alpha is a 65 kDa protein and a member of the steroid family of nuclear receptors. Estrogen Receptor alpha is ... Like other steroid hormone receptors, Estrogen Receptors are intracellular proteins. Estrogen Receptors play an important role ... Related Estrogen Receptor Blog Posts. Check out the latest blog posts on Estrogen Receptor. Cytokeratin 18 - A Intermediate ...https://www.novusbio.com/common-name/estrogen-receptor
Postmenopausal Osteoporosis: Clinical Guide on Selective Estrogen Receptor Modulators
Estrogen Dominance. Estrogen dominance is a condition with relatively high levels of estrogen and diminished progesterone ... Postmenopausal Osteoporosis: Clinical Guide on Selective Estrogen Receptor Modulators. by Kathy Jones on March 2, 2012 at 8:55 ... This clinical guide details the role of selective estrogen receptor modulators (SERMs) against postmenopausal osteoporosis as ... Furthermore what agent is used (estrogen, SERM, bisphosphonates) may vary over a woman's life time. The clinical guide from the ...http://www.medindia.net/news/postmenopausal-osteoporosis-clinical-guide-on-selective-estrogen-receptor-modulators-98272-1.htm
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