*  Research | Mark M. Davis Lab | Stanford Medicine
... of T cell receptor binding and signal transduction and the dynamics of molecular movement at the T cell/antigen-presenting cell ... These peptide-MHC complexes are then recognized by the T cell antigen receptor (TCR), an antibody-like molecule present on most ... This is a critical event in the immune system and also arguably the best understood model for cell-cell recognition. Second, we ... In the first few minutes after a T cell recognizes another cell, a dramatic rearrangement of surface molecules and ...
  http://med.stanford.edu/davislab/Research.html
*  Mechanisms for T cell receptor triggering. - Oxford Neuroscience
This complexity may reflect the uniquely demanding nature of TCR-mediated antigen recognition, which requires the detection of ... There is considerable controversy about the mechanism of T cell receptor (TCR) triggering, the process by which the TCR ... There is considerable controversy about the mechanism of T cell receptor (TCR) triggering, the process by which the TCR ... Animals, Antigen-Presenting Cells, CD3 Complex, Humans, Lymphocyte Activation, Major Histocompatibility Complex, Mice, Protein ...
  https://www.neuroscience.ox.ac.uk/publications/103638
*  The human T cell receptor: appearance in ontogeny and biochemical relationship of alpha and beta subunits on IL-2 dependent...
This glycoprotein shares several peptides in common with clonotypic structures on an IL-2 dependent T cell clone. In addition, ... has recently been identified on IL-2 dependent T cell clones as a 90 kd disulfide-linked heterodimer comprised of one 49-51 kd ... The human T cell receptor for antigen (Ti) ... The human T cell receptor for antigen (Ti) has recently been ... The human T cell receptor: appearance in ontogeny and biochemical relationship of alpha and beta subunits on IL-2 dependent ...
  https://www.neuroscience.ox.ac.uk/publications/4460
*  Aalysis of immune receptor diversity and oligoclonality in responses to vaccinati - Andrew Fire
... and T cell receptor (TCR) genes from lymphocytes in human subjects responding to several dis... ... 2016) Individual heritable differences result in unique cell lymphocyte receptor repertoires of naïve and antigen-experienced ... These data will provide a fine-detailed view of the number, size, and receptor sequence features of expanded B and T cell ... We will carry out deep sequencing of rearranged immunoglobulin (Ig) and T cell receptor (TCR) genes from lymphocytes in human ...
  http://grantome.com/grant/NIH/U19-AI090019-05-7081
*  A role for rebinding in rapid and reliable T cell responses to antigen. - Oxford Neuroscience
In this theoretical study, we investigate the role of localized rebinding between a T cell receptor and an antigen. We show ... We demonstrate that T cell receptor coreceptors, but not receptor clustering, are important in promoting localized rebinding, ... cells and are able to discriminate between potential stimuli based on the kinetic parameters of the T cell receptor-antigen ... However, we additionally show that all our results are recapitulated when we use a detailed T cell receptor signaling model. We ...
  https://www.neuroscience.ox.ac.uk/publications/237779
*  activated T cell apoptosis QuickView - Correlation Engine
... end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor ... A type of T cell apoptosis that occurs towards the ... QuickView for activated T cell apoptosis (biogroup) *NextBio ... CCR5 Inhibitor Treatment Intensification on CD4+ T-cell Recovery. *A Multipeptide Vaccine Plus Toll-Like Receptor Agonists in ... Activation-induced cell death limits effector function of CD4 tumor-specific T cells. ...
  http://www.nextbio.com/b/search/ov/activated%20T%20cell%20apoptosis?id=34966&type=biogroup
*  T Cell Receptor (TCR) V beta-2 - AM08119SR-N | acris-antibodies.com
The receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, ... T Cell Receptor (TCR) V beta-2, 0.1 mg. ... T cell receptors recognise foreign antigens which have been ... Product Description for T Cell Receptor (TCR) V beta-2. Mouse anti Chicken T Cell Receptor (TCR) V beta-2 TCR3.. Presentation: ... Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, ...
  https://www.acris-antibodies.com/antibodies/primary-antibodies/t-cell-receptor-tcr-v-beta-2-am08119sr-n.htm
*  Identification of T cell receptor recognition residues for a viral peptide presented by HLA B27. - The Kennedy Institute of...
... was studied using HLA B27-restricted influenza-specific cytotoxic T cell (CTL) clones, of defined T cell receptor (TcR) usage, ... The fine specificity of T cell recognition of peptide analogues of the influenza nucleoprotein epitope, NP 383-391 SRYWAIRTR, ... Receptors, Antigen, T-Cell, alpha-beta, T-Lymphocytes, Cytotoxic, Viral Core Proteins ... was studied using HLA B27-restricted influenza-specific cytotoxic T cell (CTL) clones, of defined T cell receptor (TcR) usage, ...
  https://www.kennedy.ox.ac.uk/publications/35613
*  Promising Cell-Based Immunotherapy Using Gamma Delta T Cells: Together Is Better | Clinical Cancer Research
... treat cancer has been the focus of much interest in the past years and led to the recent success of chimeric antigen receptors- ... Control of self-reactive cytotoxic T lymphocytes expressing gamma delta T cell receptors by natural killer inhibitory receptors ... both teams performed in-depth γδ T-cell receptor (TCR) TCR repertoire analysis of the generated γδ T-cell lines. Although not ... Vδ2neg γδ T cells have been largely neglected in cancer cell therapy because of the limited knowledge about the antigens they ...
  http://clincancerres.aacrjournals.org/content/20/22/5573
*  CD5 Expression Is Developmentally Regulated By T Cell Receptor (TCR) Signals and TCR Avidity | JEM
1993) T cell development in mice that lack the ζ chain of the T cell antigen receptor complex. Science 261:918-921, pmid: ... 1996) Composition and function of T-cell receptor and B-cell receptor complexes on precursor lymphocytes. Curr Opin Immunol 8: ... 1995) Of ITAMs and ITIMs: turning on and off the B cell antigen receptor. J Exp Med 181:1953-1956, pmid:7539033.. ... Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages. Nature. 360:225-231. (See ...
  http://jem.rupress.org/content/188/12/2301
*  Role of framework mutations and antibody flexibility in the evolution of broadly neutralizing antibodies | eLife
Method for identification of condition-associated public antigen receptor sequences Mikhail V Pogorelyy et al. ...
  https://elifesciences.org/articles/33038v1
*  About Us - The Center for Health and Wellbeing
I've done the Antigen Receptor shot, Nuerorecover and Candida program.". Todd C. - Carmel Valley - San Diego, CA ...
  http://chwbonline.com/about-center-for-health-and-wellbeing/
*  Pasireotide & Everolimus in Adult Patients With Radioiodine-Refractory Differentiated & Medullary Thyroid Cancer - Full Text...
Patients with prior or concurrent malignancy except for the following: adequately treated basal cell or squamous cell skin ... Pasireotide works by binding to a protein called somatostatin receptor, which is expressed in many tissues throughout the body ... Presence of Hepatitis B surface antigen (HbsAg).. *Presence of Hepatitis C antibody test (anti-HCV). ... Neoplasms, Germ Cell and Embryonal. Neoplasms by Histologic Type. Adenocarcinoma. Carcinoma. Neoplasms, Glandular and ...
  https://clinicaltrials.gov/ct2/show/NCT01270321?term=sirolimus+cancer&recr=Open&rank=17
*  Tissue expression of WWTR1 - Staining in skeletal muscle - The Human Protein Atlas
Cell cycle intensity correlation. Cell cycle spatial correlation. Cell cycle biologically. Custom data cell cycle dependant. - ... G-protein coupled receptors. Mapped to UniProt SWISS-PROT. Nuclear receptors. Plasma proteins. Potential drug targets. ... Blood group antigen proteins. Cancer-related genes. Candidate cardiovascular disease genes. CD markers. Citric acid cycle ... Cell category (RNA). Cancer category (RNA). Tissue detectable (RNA). Cell line detectable (RNA). Cancer detectable (RNA). ...
  http://www.proteinatlas.org/ENSG00000018408-WWTR1/tissue/skeletal+muscle
*  Recombinant Human PD1 protein (ab114177) | Abcam
Cell Biology. Epigenetics. Metabolism. Developmental Biology. By research area. Immunology. Microbiology. Neuroscience. Signal ... Cell and tissue imaging tools. Cellular and biochemical assays. By product type. Proteins and Peptides. Proteomics tools. ... Cell Biology Apoptosis Receptors Death Receptors Share by email Recombinant Human PD1 protein (ab114177). ...
  http://www.abcam.com/recombinant-human-pd1-protein-ab114177.html
*  PerCP Anti-Human CD2 (RPA-2.10) Flow Cytometry Reagents, Recombinant Proteins, PCR Reagents
CD2, also known as LFA-2, is a receptor for CD58 in the human and is expressed on the cell surface of 80-90% of human ... Leucocyte Typing IV: White Cell Differentiation Antigens. Oxford University Press. New York. ... LFA-2, T11, Sheep Red Blood Cell Receptor (SRBC-R), Ly-37. ... CD2 mediates lymphocyte adhesion and is involved in T cell ...
  https://www.tonbobio.com/antibodies-and-reagents/percp-anti-human-cd2-rpa-2-10.html
*  Pfizer and Astellas Announce Positive Top-Line Results from Phase 3 PROSPER Trial of XTANDI (enzalutamide) in Patients with Non...
... is an androgen receptor inhibitor that blocks multiple steps in the androgen receptor signaling pathway within the tumor cell. ... PROSPER enrolled patients with prostate cancer that had progressed, based on a rising prostate-specific antigen (PSA) level ... In preclinical studies, enzalutamide has been shown to competitively inhibit androgen binding to androgen receptors, and ... and there is a rising prostate-specific antigen (PSA) level.[iii] Many men with non-metastatic CRPC will go on to develop ...
  https://finance.yahoo.com/news/pfizer-astellas-announce-positive-top-090000228.html
*  ASMscience | Lyme Borreliosis
... assay using recombinant VlsE1 or peptide antigens of Borrelia burgdorferi compared with 2-tiered testing using whole-cell ... The outer surface protein A of the spirochete Borrelia burgdorferi is a plasmin(ogen) receptor. Proc. Natl. Acad. Sci. USA 91: ... T-helper-cell cytokines in the early evolution of murine Lyme arthritis. Infect. Immun. 65:3107-3111.. ... Identification of candidate T-cell epitopes and molecular mimics in chronic Lyme disease. Nat. Med. 5:1375-1382.. ...
  http://www.asmscience.org/content/book/10.1128/9781555816490.chap11
*  Nitroglycerine-Induced Nitrate Tolerance Compromises Propofol Protection of the Endothelial Cells against TNF-α: The Role of...
... endothelial cell, and myeloid cell antigens in spontaneous and chemically induced hemangiosarcomas and hemangiomas in mice," ... beneficial effects of therapy with the AT1 receptor blocker telmisartan," Arteriosclerosis, Thrombosis, and Vascular Biology, ... J.-M. Li and A. M. Shah, "Mechanism of endothelial cell NADPH oxidase activation by angiotensin II. Role of the p4. 7. phox. ... in endothelial cell superoxide production in response to phorbol ester and tumor necrosis factor-α," Circulation Research, vol ...
  https://www.hindawi.com/journals/omcl/2013/678484/ref/
*  Chelators - MP Biomedicals
Apoptosis Cell Biology Immuno Solutions Molecular Biology Proteomics Quality Control Research Diet Sample Preparation Solid ... Anti-Macrophage Scavenger Receptor, Human. *Anti-Melanoma Marker, Human. *Anti-Metalloproteinase 2, Human ... Culture Detect Detection Reagents IHC Isolate (Blood Fractionation) Mycoplasma Removal Stem Cell Antibodies >> View All Immuno ...
  http://www.mpbio.com/index.php?cPath=1_6_33_223&country=223
*  RPL24P6 Gene - GeneCards | RPL24P6 Pseudogene
No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ... Cell Line Products. * GenScript Custom overexpressing Cell Line Services for RPL24P6 * Browse ESI BIO Cell Lines and PureStem ... NURSA nuclear receptor signaling pathways regulating expression of RPL24P6 Gene:. RPL24P6 Genes that share expression patterns ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=RPL24P6
*  Weight abnormalities in IL-6-sIL-6R mice. (A) An IL-6 | Open-i
Antigens, CD/metabolism. *Body Weight. *Cell Differentiation. *Cell Division. *Cell Separation. *Cytokine Receptor gp130 ... Soluble cytokine receptors modulate the activity of their cognate ligands. Interleukin (IL)-6 in association with the soluble ... Soluble cytokine receptors modulate the activity of their cognate ligands. Interleukin (IL)-6 in association with the soluble ... The high numbers of hematopoietic progenitor cells were reflected by a strong increase of peripheral blood cell numbers. ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2196150_JEM.peters1a&req=4
*  Home Page | Phoenix Children's Hospital
Phoenix Children's is one of only a handful of centers in the nation offering Chimeric Antigen Receptor T-cell (CAR-T) therapy ...
  http://www.phoenixchildrens.org/es
*  PVALB Gene - GeneCards | PRVA Protein | PRVA Antibody
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for PVALB Gene. ... Suggested Antigen Peptide Sequences for PVALB Gene. GenScript: Design optimal peptide antigens:. *Parvalbumin (B1AH73_HUMAN) ... NURSA nuclear receptor signaling pathways regulating expression of PVALB Gene:. PVALB SOURCE GeneReport for Unigene cluster for ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=PVALB&simap=5&rf=/home/genecards/current/website/carddisp.pl
*  Patents filed at Aug 15 2017 | To apply a fluid to a substrate | Patents.com
Somatostatin receptor-based cancer therapy. Methods and composition for cell-based therapy as well as somatostatin receptor- ... Immunogenic compositions comprising an M72 related antigen, wherein the conductivity of the composition is 13 mS/cm or lower, ...
  http://es.patents.com/isd-20170815-p86.html