*  Disorders of the calcium-sensing receptor: Familial hypocalciuric hypercalcemia and autosomal dominant hypocalcemia
... was caused by inactivating mutations in the gene for the calcium-sensing receptor (CaSR, sometimes referred to as CaR) had two ... The calcium-sensing receptor is required for normal calcium homeostasis independent of parathyroid hormone. J Clin Invest 2003 ... The calcium-sensing receptor is a target of autoantibodies in patients with autoimmune polyendocrine syndrome type 1. J Clin ... The calcium-sensing receptor (CaSR) defends against hypercalcemia independently of its regulation of parathyroid hormone ...
  https://www.uptodate.com/contents/disorders-of-the-calcium-sensing-receptor-familial-hypocalciuric-hypercalcemia-and-autosomal-dominant-hypocalcemia
*  PTH parathyroid hormone [Homo sapiens (human)] - Gene - NCBI
type 1 parathyroid hormone receptor binding IMP Inferred from Mutant Phenotype. more info ... parathyroid hormone. Names. parathormone. parathyrin. parathyroid hormone 1. prepro-PTH. preproparathyroid hormone. ... G-protein-coupled receptors. Family B GPCRs include secretin, calcitonin, parathyroid hormone/parathyroid hormone-related ... PTH parathyroid hormone [Homo sapiens] PTH parathyroid hormone [Homo sapiens]. Gene ID:5741 ...
  https://www.ncbi.nlm.nih.gov/gene?LinkName=pubmed_gene_citedinomim&from_uid=6220408
*  Parathyroid hormone-related protein - Wikipedia
PTHrP shares the same N-terminal end as parathyroid hormone and therefore it can bind to the same receptor, the Type I PTH ... PTHLH, BDE2, HHM, PLP, PTHR, PTHRP, parathyroid hormone-like hormone, parathyroid hormone like hormone. ... Parathyroid hormone-related protein (or PTHrP) is a protein member of the parathyroid hormone family. It is occasionally ... "Entrez Gene: PTHLH parathyroid hormone-like hormone".. *^ Cingolani G, Bednenko J, Gillespie MT, Gerace L (December 2002). " ...
  https://en.wikipedia.org/wiki/Parathyroid_hormone-related_protein
*  TOP: Recombinant Human Parathyroid Hormone (ALX1-11) on Fracture Incidence in Women With Postmenopausal Osteoporosis - Full...
... and selective estrogen receptor modulation (SERM) washout. ... Study Type :. Interventional (Clinical Trial) Actual Enrollment ... Treatment of Osteoporosis with Parathyroid Hormone Study Group. Effect of recombinant human parathyroid hormone (1-84) on ... Parathyroid hormone (PTH), a polypeptide consisting of 84 amino acids that is synthesized and secreted by the parathyroid ... TOP: Recombinant Human Parathyroid Hormone (ALX1-11) on Fracture Incidence in Women With Postmenopausal Osteoporosis. The ...
  https://clinicaltrials.gov/ct2/show/NCT00172081?term=Porencephaly&rank=17
*  Parathyroid hormone 2 receptor - Wikipedia
Receptor, Parathyroid Hormone, Type 2 at the US National Library of Medicine Medical Subject Headings (MeSH) This article ... 2004). "Agonist-specific regulation of parathyroid hormone (PTH) receptor type 2 activity: structural and functional analysis ... "Parathyroid Hormone Receptors: PTH2". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical ... This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more ...
  https://en.wikipedia.org/wiki/Parathyroid_hormone_2_receptor
*  Human PTH2R/beta-Arrestin Stable Cell Line-CHO - Creative Biogene
This protein is a receptor for parathyroid hormone (PTH). This receptor is more s ... The protein encoded by this gene is a member of the G-protein coupled receptor family 2. ... The parathyroid hormone (PTH) receptor type 2 (PTHR2) is a receptor for PTH and tuberoinfundibular peptide TIP39. Unlike the ... parathyroid hormone receptor 2 , PTHR2; PTH2 receptor; parathyroid hormone receptor 2; PTHR2; ...
  https://www.creative-biogene.com/Human-PTH2R-beta-Arrestin-Stable-Cell-Line-CHO-CSC-RG1592-196284-11.html
*  TIP39 - Wikipedia
2004). "Agonist-specific regulation of parathyroid hormone (PTH) receptor type 2 activity: structural and functional analysis ... Misiano P, Scott BB, Scheideler MA, Garnier M (2004). "PTH2 receptor-mediated inhibitory effect of parathyroid hormone and ... a ligand of the parathyroid hormone receptor family". J. Endocrinol. 174 (1): 95-102. doi:10.1677/joe.0.1740095. PMID 12098667 ... receptor. N-terminal truncation of TIP39 reverses PTH2 receptor/PTH1 receptor binding selectivity". J. Biol. Chem. 275 (35): ...
  https://en.wikipedia.org/wiki/TIP39
*  Print 1 | T Helper Cell | Insulin Resistance
plasma parathyroid hormone (PTH) levels.3. and 1. PTH stimulates the transcription of 1αhydroxylase and nuclear receptor 4A2 ( ... VDR: vitamin D receptor. and combinations of Bsm1/Apa1/Taq1 have been shown to influence susceptibility to type 1 DM in Germans ... Suppress the expression of 1 α-hydroxylase Parathyroid glands: →Decrease parathyroid hormone Figure 1: The synthesis and ... Parathyroid Hormone (PTH).25 (OH)2 vitamin D (2000 IU/d for 6 months) 1. Vitamin D and PTH have also been associated with a ...
  https://www.scribd.com/document/196947022/Print-1
*  Osteoporosis Drugs Market, Industry Analysis & Forecasts
Osteoporosis market is segmented on the basis of Drug Type, Application and Geography. It covers Industry Analysis & Forecasts ... in this report include Parathyroid Hormone Therapy (PTH) Drugs, Bisphosphonates, Calcitonin, Selective Estrogen Receptor ... Based on applications the market is classified into Primary Type 1 Osteoporosis, Primary Type 2 Osteoporosis and Secondary ... The global osteoporosis market, is segmented on the basis of Drug Type, Application and Geography. The drug types considered, ...
  https://www.alliedmarketresearch.com/osteoporosis-drugs-market
*  SLC9A3R1 gene - Genetics Home Reference - NIH
... regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The ... Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene ... Nephrolithiasis/osteoporosis, hypophosphatemic, 2 (NPHLOP2): A disease characterized by decreased renal phosphate absorption, ...
  https://ghr.nlm.nih.gov/gene/SLC9A3R1
*  Riesgo Cardiovascular y osteoporosis
... parathyroid hormone; PTH1R, parathyroid hormone 1 receptor; RANKL, receptor activator of nuclear factor κB ligand; ROS, ... His risk profile includes type 2 diabetes mellitus, arterial hypertension and a 60- packyear history of cigarette smoking ... OPG prevents the interaction of RANKL with its receptor. Wnt signaling, which is important for osteoblast differentiation, is ... it interacts with integrin receptors resulting in osteoclast activation. PTH inhibits osteoblast activation and increases bone ...
  https://www.slideshare.net/neonety/riesgo-cardiovascular-y-osteoporosis
*  What Is Genetic Disorder - Pseudohypoparathyroidism - Medicalrealm
... parathyroid hormone will binds to the parathyroid hormone receptor which later interact with the G protein. This will lead to ... In normal individual, parathyroid hormone will binds to the parathyroid hormone receptor which later interact with the G ... Type 1 pseudohypoparathyroidism occurs due to Gs-α deficiency, This will cause an impairment of the coupling of parathyroid ... Pseudohypoparathyroidism is associated with defect of the parathyroid hormone receptor. Pseudohypoparathyroidism is an ...
  http://www.medicalrealm.net/what-is-genetic-disorder---pseudohypoparathyroidism.html
*  Enchondromatosis, Multiple, Ollier Type disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials
An important gene associated with Enchondromatosis, Multiple, Ollier Type is PTH1R (Parathyroid Hormone 1 Receptor), and among ... Parathyroid Hormone 1 Receptor. 377.32. Causative germline mutation (loss of function) 56 ... peptide hormone receptor binding. GO:0051428 9.37. PTHLH PTPN11 6. heparan sulfate N-acetylglucosaminyltransferase activity. GO ... Protein Tyrosine Phosphatase, Non-Receptor Type 11. 15.28. DISEASES inferred 14 GeneCards inferred via :. DISEASES inferred ( ...
  http://www.malacards.org/card/enchondromatosis_multiple_ollier_type
*  Chromosome 3 (human) - Wikipedia
... oxytocin receptor PHF7 encoding protein PHD finger protein 7 PTHR1: parathyroid hormone receptor 1 QRICH1: encoding protein ... T-cell receptor-associated transmembrane adapter 1 USH3A: Usher syndrome 3A ZBED2: encoding protein Zinc finger BED-type ... type V, alpha (long QT syndrome 3) SETD5: SET domain containing 5 SFMBT1: Scm-like with four mbt domains 1 SLC25A20: solute ... nonpolyposis type 2 (E. coli) MYRIP: Myosin VIIA and Rab interacting protein NBEAL2: Neurobeachin-like 2 NKTR: NK-tumor ...
  https://en.wikipedia.org/wiki/Chromosome_3_(human)
*  Low Magnesium Levels and FGF-23 Dysregulation Predict Mitral Valve Calcification as well as Intima Media Thickness in...
... parathyroid hormone (PTH) ≥ 350 pg/mL, phosphorus , 5.5 mg/dL, type 1 diabetes, renal disease other than diabetic nephropathy, ... antihypertensive drugs such as antagonist of receptor of angiotensin (ARA) and angiotensin converting enzyme inhibitor (ACEI), ... and parathyroid hormone with cardiac mortality risk in chronic hemodialysis patients," Journal of the American Society of ... 2 (. ), 3 (. ), and 4 (. ). Results of post hoc analysis: a-. versus Group 1, b-. versus Group 2, and c-. versus Group 3. ...
  https://www.hindawi.com/journals/ije/2015/308190/
*  Knockin mouse with mutant Gα11 mimics human inherited hypocalcemia and is rescued by pharmacologic inhibitors - Employees
... low parathyroid hormone (PTH), and hyperphosphatemia. We have generated knockin mice harboring the point mutation GNA11 c.C178T ... Recently, we identified gain-of-function mutations in Gα11 in patients with autosomal-dominant hypocalcemia type 2 (ADH2), an ... Treatment with NPS 2143, a negative allosteric modulator of the calcium-sensing receptor (CASR), increased PTH and calcium ... G proteins play critical roles in transducing extracellular signals generated by 7-transmembrane domain receptors. Somatic gain ...
  http://drug.ku.dk/employees/?pure=en%2Fpublications%2Fknockin-mouse-with-mutant-g11-mimics-human-inherited-hypocalcemia-and-is-rescued-by-pharmacologic-inhibitors
*  LRP2 elisa kit | Human Low Density Lipoprotein Receptor Related Protein 2 (LRP2) ELISA Kit-NP 004516.2
Human Low Density Lipoprotein Receptor Related Protein 2 (LRP2) ELISA Kit-NP_004516.2 (MBS2023773) product datasheet at ... May participate in regulation of parathyroid- hormone and para-thyroid-hormone-related protein release. Defects in LRP2 are the ... Protein type: Receptor, misc.; Membrane protein, integral; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog ... Metabolism Of Steroid Hormones And Vitamin D Pathway antibodies. Metabolism Of Steroid Hormones And Vitamin D Pathway Diagram. ...
  https://www.mybiosource.com/prods/ELISA-Kit/Human/Low-Density-Lipoprotein-Receptor-Related-Protein-2-LRP2/LRP2/datasheet.php?products_id=2023773
*  Nutrients | Free Full-Text | The Role of Vitamin D in Blood Pressure, Endothelial and Renal Function in Postmenopausal Women |...
Vitamin D is a pro-hormone that plays an essential role in the vasculature and in kidney function. Aims: To review the extra- ... Selective vitamin D receptor activation with paricalcitol for reduction of albuminuria in patients with type 2 diabetes (vital ... Sai, A.J.; Walters, R.W.; Fang, X.; Gallagher, J.C. Relationship between vitamin D, parathyroid hormone, and bone health. J. ... Reis, J.P.; von Muhlen, D.; Kritz-Silverstein, D.; Wingard, D.L.; Barrett-Connor, E. Vitamin D, parathyroid hormone levels, and ...
  http://www.mdpi.com/2072-6643/5/7/2590/htm
*  Jansen's metaphyseal chondrodysplasia - Wikipedia
... is a disease that results from ligand-independent activation of the type 1 of the parathyroid hormone receptor (PTHR1), due to ... Constitutively Activated Receptors for Parathyroid Hormone and Parathyroid Hormone-Related Peptide in Jansen's Metaphyseal ... A Novel Parathyroid Hormone (PTH)/PTH-Related Peptide Receptor Mutation in Jansen's Metaphyseal Chondrodysplasia, The Journal ... Monophosphate Signaling Pathway by Parathyroid Hormone (PTH)/PTH-Related Peptide Receptors Mutated at the Two Loci for Jansen's ...
  https://en.wikipedia.org/wiki/Jansen's_metaphyseal_chondrodysplasia
*  Plus it
... parathyroid hormone; Ptpre, protein tyrosine phosphatase, receptor type, epsilon polypeptide; Pygm, phosphorylase, glycogen ... dopamine receptor D4; Echs1, enoyl-CoA hydratase, short chain 1, mitochondrial; Fgfr2, fibroblast growth factor receptor 2; ... a hormone cocktail designed to stabilize the circulating levels of the most important sodium- and water-retaining hormones was ... Ninety minutes after the start of the hormone cocktail infusion, renal perfusion pressure was set to 110 mmHg for WKY and to ...
  http://physiolgenomics.physiology.org/content/8/1/15
*  Dr Samuel Webster
2003). Expression of type X collagen, Indian hedgehog and parathyroid hormone related-protein in normal and tibial ... 2003). The distribution of Notch receptors and their ligands during articular cartilage development. Journal of Anatomy 202(6) ... 2015). Evaluation of a novel skin tone meter and the correlation between Fitzpatrick skin type and skin color. Photonics & ... PM-349D Doctor as Scholar and Scientist 2 This module further develops the student's scientific knowledge, building on the ...
  https://www.swan.ac.uk/staff/medicine/learningandteaching/webstersv/
*  WikiGenes - AmbotzHAA1166 - (2S,3R)-2-amino-3-hydroxy-butanamide
Constitutively activated receptors for parathyroid hormone and parathyroid hormone-related peptide in Jansen's metaphyseal ... Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor. Franzén, P., ten ... Expression cloning of the TGF-beta type II receptor, a functional transmembrane serine/threonine kinase. Lin, H.Y., Wang, X.F ... Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic ...
  https://www.wikigenes.org/e/chem/e/444078.html
*  parathyroid hormone
b>Parathyroid hormone-related protein (PTHrP), and its receptor, parathyroid hormone receptor 1 (PTH1R), expressed in almost ... Vitamin D deficiency is an increasingly recognized comorbidity in patients with both type 1 (T1D) and type 2 diabetes, ... and hormone antagonists hormone substitutes hormones , hormones , peptide hormones , parathyroid hormone ... The PTH/PTHrP receptor (PTHR), a G protein-coupled receptor (GPCR) of the B family, transmits both parathyroid hormone (PTH) ...
  https://www.labome.org/topics/chemicals/and/hormones/peptide/parathyroid-hormone-12158.html
*  Vitamin D Supplementation with Cholecalciferol can Improve Glycemic Control
Vitamin D supplementation with cholecalciferol can help improve glycemic control and lipid profiles in type 2 patients with ... has been an area of focus for researchers due to its effects on the parathyroid hormone, glucose homeostasis and immune system ... Home / Conditions / Type 2 Diabetes / Cholecalciferol Improves Glycemic Control. Cholecalciferol Improves Glycemic Control. Dec ... It has been postulated that vitamin D may reduce insulin resistance indirectly through upregulation of the insulin receptor ...
  http://www.diabetesincontrol.com/cholecalciferol-improves-glycemic-control/
*  Parathyroid hormone 1 receptor - Wikipedia
"Nuclear localization of the type 1 parathyroid hormone/parathyroid hormone-related peptide receptor in MC3T3-E1 cells: ... Parathyroid hormone/parathyroid hormone-related peptide receptor also known as parathyroid hormone 1 receptor (PTH1R) is a ... PTH1R functions as a receptor for parathyroid hormone (PTH) and for parathyroid hormone-related protein (PTHrP), also called ... "Cloning of a parathyroid hormone/parathyroid hormone-related peptide receptor (PTHR) cDNA from a rat osteosarcoma (UMR 106) ...
  https://en.wikipedia.org/wiki/Parathyroid_hormone_1_receptor