*  Acute myelogenous leukemia. Causes, symptoms, treatment Acute myelogenous leukemia
Treatment Acute myelogenous leukemia. Symptoms and causes Acute myelogenous leukemia Prophylaxis Acute myelogenous leukemia ... and molecular genetic studies (DNA and RNA tests of the cancer cells). The primary treatment of AML is chemotherapy. Radiation ... There are two phases of treatment for AML. The first phase is called induction therapy. The purpose of induction therapy is to ... Treatment may include a combination of cytarabine, daunorubicin, idarubicin, etoposide, cyclophosphamide, mitoxantrone, or ...
  http://drugster.info/medic/term/acute-myelogenous-leukemia/
*  Tandutinib Inhibits the Akt/mTOR Signaling Pathway to Inhibit Colon Cancer Growth | Molecular Cancer Therapeutics
... chemotherapy, and radiation, are often inadequate in treating this disease, new treatment options are critically needed. ... In conclusion, our studies show that treatment of colon cancer cells with tandutinib results in significant inhibition of tumor ... Chemotherapeutic compounds currently being used for the treatment of colorectal cancer include 5-flurouracil, oxaliplatin, and ... leading to an inhibition of Akt and Erk signaling and to induction of apoptosis in FLT3-ITD-positive human AML cell lines (5). ...
  http://mct.aacrjournals.org/content/12/5/598?rss=1
*  Head and neck cancer - Wikipedia
Treatment may include a combination of surgery, radiation therapy, chemotherapy, and targeted therapy. Following treatment of ... These staging systems attempt to standardize clinical trial criteria for research studies, and attempt to define prognostic ... there has been an emphasis on the use of various induction or concomitant chemotherapy regimens. Surgery as a treatment is ... the 2006 publication of a randomized clinical trial comparing radiation treatment plus cetuximab versus radiation treatment ...
  https://en.wikipedia.org/wiki/Head_and_neck_cancer
*  Benzene Exposure and Risk of Non-Hodgkin Lymphoma | Cancer Epidemiology, Biomarkers & Prevention
Numerous studies have reported associations between benzene exposure and the induction of lymphomas in mice. Studies by ... The eight studies showing increased risks are diverse in nature and include the recent study of Miligi, Vineis, Costantini, and ... Studies in experimental animals and of therapy-related lymphoma in the clinical setting support this finding. Potential ... Interestingly, as discussed by Krishnan and Morgan in this issue, numerous studies show that alkylating agent chemotherapy also ...
  http://cebp.aacrjournals.org/content/16/3/385.full
*  Frontiers | Paradigm Shift in Dendritic Cell-Based Immunotherapy: From in vitro Generated Monocyte-Derived DCs to Naturally...
Upcoming treatment paradigms aim to include several primary dendritic cell subsets in a single vaccine as preclinical studies ... The first clinical trials not only showed increased survival rates but also the induction of diversified anticancer immune ... Upcoming treatment paradigms aim to include several primary dendritic cell subsets in a single vaccine as preclinical studies ... The first clinical trials not only showed increased survival rates but also the induction of diversified anticancer immune ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2014.00165/full
*  In vitro and In vivo Radiation Sensitization of Human Tumor Cells by a Novel Checkpoint Kinase Inhibitor, AZD7762 | Clinical...
As was seen for in vitro studies (Supplementary Fig. S7A-B; Fig. 3A-B), radiation treatment induced γ-H2AX in a time-dependent ... Lastly, radiation was shown to induce cyclin B and AZD7762 markedly inhibited its induction, consistent with the radiation- ... Cytotoxic chemotherapy combined with radiation is currently used to enhance local tumor control at the expense of increasing ... Other mechanisms identified in the current study that may be more pertinent include the effects of AZD7762 on radiation-induced ...
  http://clincancerres.aacrjournals.org/content/16/7/2076
*  Purpose To assess the effect of induction chemotherapy, and associated tumor
Radiation All individuals received the 3-dimensionally-planned external beam radiation treatment. The treated quantities were ... Most individuals were treated with standard beam plans [i.e., initial opposed anterior-posterior (AP/PA) fields to include the ... Nevertheless, many of the individuals were treated on prospective studies there the prospective volume and doses were specified ... 303 individuals with lung malignancy were enrolled in a prospective IRB-approved clinical study to better understand RT-induced ...
  http://researchhunt.com/2017/09/20/purpose-to-assess-the-effect-of-induction-chemotherapy-and-associated-tumor/
*  Primary Vaginal Myeloid Sarcoma: A Rare Case Report and Review of the Literature
Treatment is variable and often delayed. Treatment of isolated MS similar to leukemic AML and induction chemotherapy is now the ... Treatment options include systemic treatment for AML, with or without local therapies. It is important to consider individual ... surgical and radiation therapy are accepted treatment modalities; however, their precise roles in the treatment algorithm are ... a clinical review," Journal of Clinical Oncology, vol. 13, no. 7, pp. 1800-1816, 1995. View at Google Scholar · View at Scopus ...
  https://www.hindawi.com/journals/criog/2015/957490/
*  Hematology <span class="indicator">...
Treatment approaches for blood cancers may include chemotherapy, radiation oncology, stem cell or marrow transplantation, or ... which includes standard care and/or clinical trials. Clinical Trials offering novel treatment options are available through ... Yale Cancer Center maintains a tissue bank used for novel research studies in cancer treatment and prevention. ... Hematology plays an important role in the continuity of care of patients from inpatient induction therapy, through outpatient ...
  http://www.yalecancercenter.org/patient/programs/hematology/
*  Genetics of Skin Cancer (PDQ®) (Health professionals) | OncoLink
Similarly, treatment of BCC of the skin with radiation therapy may result in induction of large numbers of additional BCCs. ... Few studies have examined motivation and interest in genetic testing for melanoma risk. In summary, the findings include the ... Getting Cancer Treatment? Start Here! * Bone Marrow Transplants * Chemotherapy * Clinical Trials * Complementary and ... Although few studies on treatment of SCC in the XP population have been done, in most cases treatment is similar to what would ...
  https://www.oncolink.org/healthcare-professionals/nci/pqid-CDR0000552637
*  Decision Making in Feline Cancer Patients - WSAVA2008 - VIN
... standard treatment protocols and advances in radiation and chemotherapy-based treatments. Particular emphasis will be placed ... Typical clinical signs include dyspnoea and exercise intolerance due to the presence of the space-occupying lesion and pleural ... FeLV negative cats that achieve a complete remission following induction therapy are likely to have durable (i.e., , 6 month) ... Royal (Dick) School of Veterinary Studies Hospital for Small Animals. Easter Bush, Midlothian, UK ...
  http://www.vin.com/apputil/content/defaultadv1.aspx?pId=11268&id=3866631
*  UNC spin-off receives $3 million Small Business Innovation Rese... ( Chapel Hill NC G-Zero Therapeutics ...)
While radiation and chemotherapy have therapeutic uses, too much is damaging to cells. The most important acute side effect of ... Previously, Sharpless' lab has shown that the induction of PQTM even up to 20 hours after radiation exposure protects mice from ... Examples of applications for G-Zero's technology include unexpected radiation exposures, such as the recent Fukushima nuclear ... His group showed that treatment with certain of these agents causes specific groups of bone marrow cells to temporarily stop ...
  http://www.bio-medicine.org/biology-news-1/UNC-spin-off-receives--243-million-Small-Business-Innovation-Research-Grant-21592-1/
*  Radiation Oncology/SCLC/PCI - Wikibooks, open books for an open world
1973 PMID 4354042 -- "Should initial treatment of small cell carcinoma include systemic chemotherapy and brain irradiation?" ( ... There is significant neurotoxicity present in patients completing induction chemotherapy, prior to PCI ... Calculated clinical failure: 12 months: +PCI 11% vs. -PCI 28%; 24 months +PCI 11% vs. -PCI 58% (SS) ... Results of RTOG/EORTC studies should provide clarification; in abstract publication (ASCO 2008) 25/10 appears comparable in ...
  https://en.wikibooks.org/wiki/Radiation_Oncology/SCLC/PCI
*  Distribution and Supply Agreement - Smithkline Beecham Corp. d/b/a GlaxoSmithKline and Celgene Corp - Sample Contracts and...
CLINICAL TRIAL: A randomized trial compared prednisone plus IV melphalan to prednisone plus oral melphalan in the treatment of ... While adequate animal studies have not been conducted with IV melphalan, oral (6 to 18 mg/m2 per day for 10 days) and IP (18 mg ... viii) include all Products in its Patient Assistance Program. For purposes of this clause (viii), the "Patient Assistance ... This does not mean that there is a cumulative dose below which there is no risk of the induction of secondary malignancy. The ...
  http://contracts.onecle.com/celgene/smithkline.distrib.2003.03.31.shtml
*  Acute Lymphoblastic Leukemia Treatment | OSUCCC - James
... including clinical trials, available at the OSUCCC - James to care for Acute Lymphoblastic Leukemia. ... They may recommend that your treatment be completed in phases. These include:. Remission Induction. The first treatment phase, ... Combination chemotherapy uses more than one anticancer drug. Radiation Therapy. Radiation therapy uses high-energy X-rays to ... These teams also run groundbreaking studies, and through detailed observations, evaluate the latest treatments and targeted ...
  https://cancer.osu.edu/cancer-specialties/cancer-care-and-treatment/acute-lymphoblastic-leukemia/treatment
*  Malignant Mesothelioma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - WellSpan Health Library
... therapy with induction chemotherapy followed by extrapleural pneumonectomy and adjuvant high-dose hemithoracic radiation for ... and most clinical studies show that patients with epithelial mesotheliomas have a better prognosis than patients do with ... Standard treatment options: *Symptomatic treatment to include drainage of effusions, chest tube pleurodesis, or thoracoscopic ... Treatment trials for advanced malignant mesothelioma *Many phase II trials of chemotherapy for the treatment of advanced ...
  http://www.wellspan.org/health-library/Document.aspx?id=ncicdr0000062895
*  POR - Content
Treatment options include chemotherapy, surgery, radiation and immunotherapy. In some recent studies an increased incidence of ... HCV infection may result in increased risk of SMZL due to the induction of B-cell lymphoproliferation. Because of possible ... Splenic marginal zone lymphoma (SMZL) is a rare malignant B-cell neoplasm, usually with an indolent clinical course and ... Following surgery, chemotherapy (CHOP regimen) and immunotherapy (anti-CD20 antibody) were given. At the last follow-up 15 ...
  http://por.hu/content.php?article=968
*  Protocols and Video Articles Authored by Gersende Alphonse
Photon radiation has proved its benefits in overall survival in many clinical studies. However, some patients present local ... chemotherapy and combinations of each are used in the management of the disease. In most cases, treatment fails to obtain total ... Secondly, all-trans retinoic acid (ATRA) resulted in an inhibition of ALDH activity, and induction of the differentiation and ... Since typical treatments for GBM include RT, our objective was to evaluate the efficiency of Imetelstat (TA inhibitor) combined ...
  https://www.jove.com/author/Gersende_Alphonse
*  Leukemia | definition of leukemia by Medical dictionary
Treatment is often given in several phases, with a period of induction chemotherapy to induce remission by completely ... Clinical findings such as anemia, fatigue, lethargy, fever, and bone and joint pain may be present. Physical findings include ... These studies are followed by cytochemical and cytogenetic studies of abnormal cells found in the marrow or the peripheral ... Individuals exposed to high amounts of radiation are at higher risk of developing this disease, as are those with a variety of ...
  http://medical-dictionary.thefreedictionary.com/leukemia
*  Childhood Leukemia | definition of Childhood Leukemia by Medical dictionary
Treatment is often given in several phases, with a period of induction chemotherapy to induce remission by completely ... Clinical findings such as anemia, fatigue, lethargy, fever, and bone and joint pain may be present. Physical findings include ... These studies are followed by cytochemical and cytogenetic studies of abnormal cells found in the marrow or the peripheral ... Radiofrequency radiation exposure from AM radio transmitters and childhood leukemia and brain cancer.. Childhood leukemia and ...
  https://medical-dictionary.thefreedictionary.com/Childhood+Leukemia
*  CML | definition of CML by Medical dictionary
Treatment is often given in several phases, with a period of induction chemotherapy to induce remission by completely ... Clinical findings such as anemia, fatigue, lethargy, fever, and bone and joint pain may be present. Physical findings include ... These studies are followed by cytochemical and cytogenetic studies of abnormal cells found in the marrow or the peripheral ... These genetic lesions in turn can be produced by viruses, ionizing radiation, chemotherapeutic drugs, and toxic chemicals. ...
  http://medical-dictionary.thefreedictionary.com/CML
*  Significance of Hypoxia in Malignant Glioma. Re: Evans et al. Hypoxia is important in the biology and aggression of human glial...
It is relevant to revisit the history of radiation oncology's clinical studies of hypoxic cell sensitizers for some perspective ... radiation-resistant tumor cells as one reason for treatment resistance, escalation of radiation dose is a logical consequence. ... HIF-1α induction has been shown to be of prognostic significance in several tumor types, but studies have not been performed to ... We now understand that hypoxia modulates much more than radiation efficacy. Hypoxia affects chemotherapy response (13, 14) and ...
  http://clincancerres.aacrjournals.org/content/11/10/3966
*  Leiomyosarcoma - The Clinical Advisor
Physician assistants and nurse practitioners use Clinical Advisor for updated medical guidance to diagnose and treat common ... The role of chemotherapy is less well defined. Because of the evolving nature of the state of the art in the treatment of this ... Radiation therapy is an important additional treatment for improving rates of local control when surgical margins are close, ... Preoperative induction treatment may reduce the size of tumors of distal limbs and facilitate better functional results. ...
  http://www.clinicaladvisor.com/dermatology/leiomyosarcoma/article/588858/
*  Sequential FDG-PET (Positron Emission Tomography) and Induction Chemotherapy in Locally Advanced Adenocarcinoma of the...
Intervention/treatment Phase Adenocarcinomas of the Esophagogastric Junction Radiation: neoadjuvant radiochemotherapy in ... For general information, Learn About Clinical Studies. Ages Eligible for Study: 18 Years to 75 Years (Adult, Senior). ... Staging procedures include endoscopy, endoscopic ultrasound and computed tomography (CT) of the chest and abdomen. ... Treatment. Official Title:. Sequential FDG-PET (Positron Emission Tomography) and Induction Chemotherapy in Locally Advanced ...
  https://clinicaltrials.gov/ct2/show/NCT01271322
*  Surgical management of pelvic Ewing's sarcoma
In two studies from the Mayo Clinic, patients undergoing surgery with or without adjuvant chemotherapy had higher survival ... are necessary for conclusive evidence regarding improved clinical outcome when surgical resection is used in the treatment of ... Adjuvant chemotherapy and radiation therapy have improved the survival rates for other primary bone tumors, but the prognosis ... suggest the combination of chemotherapy with alkylating agents and radiotherapy may have an enhancing effect on the induction ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2947726/