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*  A SMALL GTP-BINDING PROTEIN DISSOCIATES FROM SYNAPTIC VESICLES DURING EXOCYTOSIS
Synaptotagmin 1 directs repetitive release by coupling vesicle exocytosis to the Rab3 cycle.. Cheng Y, Wang J, Wang Y, Ding M ... A SMALL GTP-BINDING PROTEIN DISSOCIATES FROM SYNAPTIC VESICLES DURING EXOCYTOSIS. Fischer von Mollard G, SUDHOF TC, JAHN R ( ... Synthetic peptides to mimic the role of GTP binding proteins in membrane traffic and fusion.. Law GJ, Northrop AJ., Ann. N. Y. ... Study of rab6, a ras-like GTP-binding protein associated with the Golgi complex.. Goud B, Yang C, Roa M, Martinez O, Mayau V., ...
  https://pub.uni-bielefeld.de/publication/2374443
*  Anti-Rab27A Antibody | Anti-Rab27B Antibody | Rab27A Antibody | Rab27B Antibody
Rab27A is also known as RAB27A, member RAS oncogene family; GTP-binding protein Ram, RAB27, GS2, RAM, and HsT18676. Rab27B is ... Antigen: Human Rab27B recombinant protein. *Specificity: Cross-reacts with mouse and rat Rab27B; does not cross-react with Rab3 ... Rab27A: RAB27A, member RAS oncogene family; GTP-binding protein Ram, RAB27, GS2, RAM, HsT18676 ... Rab27 is a member of the Rab subfamily of Ras GTPase proteins. Rab27 protein is membrane-bound and is post-translationally ...
  http://www.clontech.com/US/Products/Cell_Biology_and_Epigenetics/Metabolic_Diseases/Rab27?sitex=10020:22372:US&PEBCL1=cq0dewn0rVAFrds7f6eOhjy8vW&PEBCL1_pses=ZG4E38B5565A326FA821CC8A3B8ED83766B0BD0FD5BDE36DA2749EFFDF887E7D827991C5D6CB44C268B54681A27F97B77B03659B503712BC66
*  Cellular functions of Rab GTPases at a glance | Journal of Cell Science
... which specifically interact with effector proteins when GTP is bound (Eathiraj et al., 2005). In the GDP-bound state, the ... 2013). Mutation spectrum in RAB3 GAP1, RAB3 GAP2, and RAB18 and genotype-phenotype correlations in warburg micro syndrome and ... when GTP is bound and 'off' when GDP is bound. Conformational differences between the GDP- and GTP-bound forms mainly involve ... Rab effectors, defined as proteins that interact specifically with the GTP-bound from of a Rab GTPase, come in many flavours ...
  http://jcs.biologists.org/content/128/17/3171
*  What does rab3 gtp-binding proteins mean?
Meaning of rab3 gtp-binding proteins. What does rab3 gtp-binding proteins mean? Information and translations of rab3 gtp- ... binding proteins in the most comprehensive dictionary definitions resource on the web. ... Definition of rab3 gtp-binding proteins in the Definitions.net dictionary. ... What does rab3 gtp-binding proteins mean?. Definitions for rab3 gtp-binding proteins. rab3 gtp-bind·ing pro·teins. Here are all ...
  https://www.definitions.net/definition/rab3%20gtp-binding%20proteins
*  Redistribution of a rab3-like GTP-binding protein from secretory granules to the Golgi complex in pancreatic acinar cells...
Redistribution of a rab3-like GTP-binding protein from secretory granules to the Golgi complex in pancreatic acinar cells ... Redistribution of a rab3-like GTP-binding protein from secretory granules to the Golgi complex in pancreatic acinar cells ... In this study, we analyzed the fate of a low M(r) GTP-binding protein during induced exocytosis and membrane retrieval using ... may be a novel rab3 isoform. In resting acinar cells, the rab3-like protein was detected primarily on the cytoplasmic face of ...
  http://jcb.rupress.org/content/124/1/43
*  rab3 GTP-Binding Proteins | Colorado PROFILES
... "rab3 GTP-Binding Proteins" by people in this website by year, and whether "rab3 GTP-Binding Proteins" was a major or minor ... rab3 GTP-Binding Proteins*rab3 GTP-Binding Proteins. *GTP-Binding Proteins, rab3 ... "rab3 GTP-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical ... Below are the most recent publications written about "rab3 GTP-Binding Proteins" by people in Profiles. ...
  https://profiles.ucdenver.edu/display/199561
*  Plus it
1990) rab3 is a small GTP-binding protein exclusively localized to synaptic vesicles. Proc Natl Acad Sci U S A 87:1988-1992. ... 1994) GTP cleavage by the small GTP-binding protein Rab3A is associated with exocytosis of synaptic vesicles induced by alpha- ... 1993) Regulation of the GTPase cycle of the neuronally expressed Ras-like GTP-binding protein Rab3A. J Biol Chem 268:22247- ... 1991) A small GTP-binding protein dissociates from synaptic vesicles during exocytosis. Nature 349:79-81. ...
  http://www.jneurosci.org/content/29/46/14534
*  Frontiers | Analysis of Synaptotagmin, SV2, and Rab3 Expression in Cortical Glutamatergic and GABAergic Axon Terminals |...
None of the proteins studied exhibited a differential laminar distribution. Since SV2B is reportedly expressed by glutamatergic ... None of the proteins studied exhibited a differential laminar distribution. Since SV2B is reportedly expressed by glutamatergic ... Immunoisolation studies showed that the expression levels of the protein isoforms varied in the three populations of SVs. ... Immunoisolation studies showed that the expression levels of the protein isoforms varied in the three populations of SVs. ...
  https://www.frontiersin.org/articles/10.3389/fncel.2011.00032/full
*  Regulation of Early Endosome Fusion In Vitro | Springer for Research & Development
Within five minutes of internalization into animal cells, lipids, solutes and trans-membrane proteins (including... ... Rab3 is a small GTP-binding protein exclusively localized to synaptic vesicles. PNAS USA 87, 1988-1992.CrossRefGoogle Scholar ... 1990). GTPbinding YPT1 protein and Ca2+ function independently in a cell-free protein transport reaction. PNAS USA 87, 355-359. ... Pfeffer, S. (1992). GTP-binding proteins in intracellular transport. Trends Cell Biol. 2, 41-46.PubMedCrossRefGoogle Scholar ...
  https://rd.springer.com/chapter/10.1007/978-3-662-02928-2_45
*  Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases
G. F. V. Mollard, G. A. Mignery, M. Baumert et al., "rab3 is a small GTP-binding protein exclusively localized to synaptic ... This includes the polyadenylate-binding protein 1 (Pabp1), predominant in EVs from metastatic duodenal tumor cell lines [26], ... K. Ohshima, K. Kanto, K. Hatakeyama et al., "Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human ... Recently, protein-loaded dexosomes were used to protect against tumor growth, whereby CD8+ T-cell responses occurred in vivo [ ...
  https://www.hindawi.com/journals/jir/2015/832057/
*  DMXL2 Gene - GeneCards | DMXL2 Protein | DMXL2 Antibody
Protein Coding), Dmx Like 2, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The ... Rabconnectin-3, a novel protein that binds both GDP/GTP exchange protein and GTPase-activating protein for Rab3 small G protein ... Protein Symbol:. Q8TDJ6-DMXL2_HUMAN. Recommended name:. DmX-like protein 2. Protein Accession:. Q8TDJ6. Secondary Accessions: * ... Protein Expression for DMXL2 Gene. See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB ...
  https://www.genecards.org/cgi-bin/carddisp.pl?gene=DMXL2
*  WikiGenes - RAB3GAP1 - RAB3 GTPase activating protein subunit 1...
A novel rabconnectin-3-binding protein that directly binds a GDP/GTP exchange protein for Rab3A small G protein implicated in ... Rab3 GEP stimulates the conversion of the GDP-bound inactive form to the GTP-bound active form, whereas Rab3 GAP stimulates the ... Therefore, the Rab3-GAP-binding site involves the switch I region of Rab3 and overlaps with the Rabphilin-binding domain [5]. ... Furthermore, Rabphilin, a putative target of Rab3, inhibited the activity of Rab3-GAP on Rab3 [5]. ...
  https://www.wikigenes.org/e/gene/e/22930.html
*  Plus it
... inducing neurodegeneration in glutaminergic interneurons by expressing a mutated GTP-binding protein Gαs (nuIs5 [Pglr-1::GFP; P ... I, J, Pan-neuronal expression of a GFP-tagged synaptic protein RAB-3 GTPase (I) and APL-1 (J) using the rab-3 promoter. K, L, ... Prab-3::GFP::rab-3] transgenic animals in which a GFP-tagged RAB-3 GTPase is expressed under the rab-3 promoter; these animals ... Prab-3::apl-1 cDNA::GFP], ynIs112 [Prab-3::apl-1 cDNA::GFP], ynIs91 [Prab-3::apl-1 cDNA::GFP], ynIs12 [Psnb-1::apl-1 cDNA], ...
  http://www.jneurosci.org/content/32/30/10156
*  Rab3-GEF Controls Active Zone Development at the Drosophila Neuromuscular Junction | eNeuro
... acting as a linker between GTP-bound Rab3 and the kinesin family proteins KIF1A and KIF1Bβ (Iwasaki et al., 1997; Niwa et al., ... Rab3 cycles between an active GTP-bound state and an inactive GDP-bound state. Following the binding of GTP, Rab3 hydrolyzes ... GTP-binding is required for Rab3 to control Brp distribution as GTP-binding defective variants of Rab3 fail to rescue the rab3 ... Orthologues of Drosophila Rab3-GEF catalyze GTP to GDP exchange to increase the population of active, GTP-bound Rab3 (Oishi et ...
  http://www.eneuro.org/content/3/2/ENEURO.0031-16.2016
*  TumorPortal
This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with ... RAB3 GTPase activating protein subunit 1 (catalytic). External References: Wikipedia GeneCards HUGO COSMIC Google Scholar NCBI ... This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non- ... catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. ...
  http://www.tumorportal.org/view?geneSymbol=RAB3GAP1
*  DMXL2 - Wikipedia
... a novel protein that binds both GDP/GTP exchange protein and GTPase-activating protein for Rab3 small G protein family". ... "A novel rabconnectin-3-binding protein that directly binds a GDP/GTP exchange protein for Rab3A small G protein implicated in ... Dmx-like 2 is a protein that in humans is encoded by the DMXL2 gene. This gene encodes a protein with 12 WD domains. Proteins ... Research has indicated that this is a result of altered function of CNS synapses (in which the protein product of Dmxl2 is ...
  https://en.wikipedia.org/wiki/DMXL2
*  RAB3B - Wikipedia
Zahraoui A, Touchot N, Chardin P, Tavitian A (1989). "The human Rab genes encode a family of GTP-binding proteins related to ... 1994). "Expression and polarized targeting of a rab3 isoform in epithelial cells". J. Cell Biol. 125 (3): 583-94. doi:10.1083/ ... Ras-related protein Rab-3B is a protein that in humans is encoded by the RAB3B gene. RAB3B has been shown to interact with ... 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. doi:10.1038 ...
  https://en.wikipedia.org/wiki/RAB3B
*  WDR7 - PrimePCR Assay and Template | Life Science | Bio-Rad
The encoded protein forms the beta subunit of rabconnectin-3 and binds directly with Rab3A GDP/GTP exchange protein and ... indirectly with Rab3A GDP/GTP activating protein; these proteins are regulators of Rab3 small G protein family members involved ... This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 ... The pathway maps illustrate protein interactions and regulation to provide a comprehensive picture of signaling and disease ...
  http://www.bio-rad.com/en-us/prime-pcr-assays/gene/wdr7-human
*  TGF-beta resistance-associated protein TRAG | definition of TGF-beta resistance-associated protein TRAG by Medical dictionary
What is TGF-beta resistance-associated protein TRAG? Meaning of TGF-beta resistance-associated protein TRAG medical term. What ... TGF-beta resistance-associated protein TRAG explanation free. ... does TGF-beta resistance-associated protein TRAG mean? ... Looking for online definition of TGF-beta resistance-associated protein TRAG in the Medical Dictionary? ... it binds directly with Rab3A GDP/GTP exchange protein and indirectly with Rab3A GDP/GTP activating protein, which regulate the ...
  https://medical-dictionary.thefreedictionary.com/TGF-beta+resistance-associated+protein+TRAG
*  Plus it
... and GTP-bound Rab11b is unexpected in view of the GTP-dependent regulation of Rab proteins (Segev, 2001; Zerial and McBride, ... Among the Rab proteins tested, we found that besides the previously described Rab3 proteins, only members of the Rab11 family ( ... The differential potency of GTP-bound versus GDP-bound Rab11b suggests that the GTP- and GDP-bound forms of Rab11b have ... by a partially inactive GTP-bound form if the GTP-bound form was expressed at 10 times higher levels than the GDP-bound form) ...
  http://www.jneurosci.org/content/23/33/10531
*  Plus it
1994) GTP cleavage by the small GTP-binding protein Rab3A is associated with exocytosis of synaptic vesicles induced by alpha- ... 1999) High affinity Rab3 binding is dispensable for Rabphilin-dependent potentiation of stimulated secretion. J Cell Sci 112: ... Given the interaction between Rab3a and rabphilin, we investigated whether the absence of the small GTP-binding protein has an ... 1991) A small GTP-binding protein dissociates from synaptic vesicles during exocytosis. Nature 349:79-81. ...
  http://www.jneurosci.org/content/21/15/5473
*  The signaling module cAMP/Epac/Rap1/PLCε/IP3 mobilizes acrosomal calcium during sperm exocytosis. - PubMed - NCBI
rap1 GTP-Binding Proteins/metabolism. *rap1 GTP-Binding Proteins/physiology. Substances. *Guanine Nucleotide Exchange Factors ... Progesterone increased the population of sperm with Rap1-GTP, Rab3-GTP, and Rab27-GTP in the acrosomal region; pretreatment ... The TAT-cAMP sponge consists of the cAMP-binding sites of protein kinase A regulatory subunit RIβ fused to the protein ...
  https://www.ncbi.nlm.nih.gov/pubmed/26704387
*  Frontiers | Molecular mechanisms driving homeostatic plasticity of neurotransmitter release | Frontiers in Cellular Neuroscience
These proteins turned out to be major presynaptic substrates for remodeling during homeostatic plasticity. Finally, we discuss ... These proteins turned out to be major presynaptic substrates for remodeling during homeostatic plasticity. Finally, we discuss ... We particularly focus on the role of presynaptic scaffolding proteins, which functionally and spatially organize synaptic ... We particularly focus on the role of presynaptic scaffolding proteins, which functionally and spatially organize synaptic ...
  https://www.frontiersin.org/articles/10.3389/fncel.2013.00244/full
*  List of MeSH codes (D08) - Wikipedia
... rab2 gtp-binding protein MeSH D08.811.277.040.330.300.400.400.100 --- rab3 gtp-binding proteins MeSH D08.811.277.040.330.300. ... gtp-binding protein alpha subunit, gi2 MeSH D08.811.277.040.330.300.200.100.300 --- gtp-binding protein alpha subunits, gq-g11 ... gtp-binding protein alpha subunits, g12-g13 MeSH D08.811.277.040.330.300.200.100.200 --- gtp-binding protein alpha subunits, gi ... ran gtp-binding protein MeSH D08.811.277.040.330.300.400.475 --- rap gtp-binding proteins MeSH D08.811.277.040.330.300.400.475. ...
  https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D08)