*  Anti-Rab27A Antibody | Anti-Rab27B Antibody | Rab27A Antibody | Rab27B Antibody
Rab27A is also known as RAB27A, member RAS oncogene family; GTP-binding protein Ram, RAB27, GS2, RAM, and HsT18676. Rab27B is ... Antigen: Human Rab27B recombinant protein. *Specificity: Cross-reacts with mouse and rat Rab27B; does not cross-react with Rab3 ... Rab27A: RAB27A, member RAS oncogene family; GTP-binding protein Ram, RAB27, GS2, RAM, HsT18676 ... Rab27 is a member of the Rab subfamily of Ras GTPase proteins. Rab27 protein is membrane-bound and is post-translationally ...
  http://www.clontech.com/US/Products/Cell_Biology_and_Epigenetics/Metabolic_Diseases/Rab27?sitex=10020:22372:US&PEBCL1=cq0dewn0rVAFrds7f6eOhjy8vW&PEBCL1_pses=ZG4E38B5565A326FA821CC8A3B8ED83766B0BD0FD5BDE36DA2749EFFDF887E7D827991C5D6CB44C268B54681A27F97B77B03659B503712BC66
*  Cellular functions of Rab GTPases at a glance | Journal of Cell Science
... which specifically interact with effector proteins when GTP is bound (Eathiraj et al., 2005). In the GDP-bound state, the ... 2013). Mutation spectrum in RAB3 GAP1, RAB3 GAP2, and RAB18 and genotype-phenotype correlations in warburg micro syndrome and ... when GTP is bound and 'off' when GDP is bound. Conformational differences between the GDP- and GTP-bound forms mainly involve ... Rab effectors, defined as proteins that interact specifically with the GTP-bound from of a Rab GTPase, come in many flavours ...
  http://jcs.biologists.org/content/128/17/3171
*  Redistribution of a rab3-like GTP-binding protein from secretory granules to the Golgi complex in pancreatic acinar cells...
Redistribution of a rab3-like GTP-binding protein from secretory granules to the Golgi complex in pancreatic acinar cells ... Redistribution of a rab3-like GTP-binding protein from secretory granules to the Golgi complex in pancreatic acinar cells ... In this study, we analyzed the fate of a low M(r) GTP-binding protein during induced exocytosis and membrane retrieval using ... may be a novel rab3 isoform. In resting acinar cells, the rab3-like protein was detected primarily on the cytoplasmic face of ...
  http://jcb.rupress.org/content/124/1/43
*  rab3 GTP-Binding Proteins | Colorado PROFILES
... "rab3 GTP-Binding Proteins" by people in this website by year, and whether "rab3 GTP-Binding Proteins" was a major or minor ... rab3 GTP-Binding Proteins*rab3 GTP-Binding Proteins. *GTP-Binding Proteins, rab3 ... "rab3 GTP-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical ... Below are the most recent publications written about "rab3 GTP-Binding Proteins" by people in Profiles. ...
  https://profiles.ucdenver.edu/display/199561
*  Plus it
1990) rab3 is a small GTP-binding protein exclusively localized to synaptic vesicles. Proc Natl Acad Sci U S A 87:1988-1992. ... 1994) GTP cleavage by the small GTP-binding protein Rab3A is associated with exocytosis of synaptic vesicles induced by alpha- ... 1993) Regulation of the GTPase cycle of the neuronally expressed Ras-like GTP-binding protein Rab3A. J Biol Chem 268:22247- ... 1991) A small GTP-binding protein dissociates from synaptic vesicles during exocytosis. Nature 349:79-81. ...
  http://www.jneurosci.org/content/29/46/14534
*  Frontiers | Analysis of Synaptotagmin, SV2, and Rab3 Expression in Cortical Glutamatergic and GABAergic Axon Terminals |...
None of the proteins studied exhibited a differential laminar distribution. Since SV2B is reportedly expressed by glutamatergic ... None of the proteins studied exhibited a differential laminar distribution. Since SV2B is reportedly expressed by glutamatergic ... Immunoisolation studies showed that the expression levels of the protein isoforms varied in the three populations of SVs. ... Immunoisolation studies showed that the expression levels of the protein isoforms varied in the three populations of SVs. ...
  https://www.frontiersin.org/articles/10.3389/fncel.2011.00032/full
*  Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases
G. F. V. Mollard, G. A. Mignery, M. Baumert et al., "rab3 is a small GTP-binding protein exclusively localized to synaptic ... This includes the polyadenylate-binding protein 1 (Pabp1), predominant in EVs from metastatic duodenal tumor cell lines [26], ... K. Ohshima, K. Kanto, K. Hatakeyama et al., "Exosome-mediated extracellular release of polyadenylate-binding protein 1 in human ... Recently, protein-loaded dexosomes were used to protect against tumor growth, whereby CD8+ T-cell responses occurred in vivo [ ...
  https://www.hindawi.com/journals/jir/2015/832057/
*  A SMALL GTP-BINDING PROTEIN DISSOCIATES FROM SYNAPTIC VESICLES DURING EXOCYTOSIS
Synaptotagmin 1 directs repetitive release by coupling vesicle exocytosis to the Rab3 cycle.. Cheng Y, Wang J, Wang Y, Ding M ... A SMALL GTP-BINDING PROTEIN DISSOCIATES FROM SYNAPTIC VESICLES DURING EXOCYTOSIS. Fischer von Mollard G, SUDHOF TC, JAHN R ( ... Synthetic peptides to mimic the role of GTP binding proteins in membrane traffic and fusion.. Law GJ, Northrop AJ., Ann. N. Y. ... Study of rab6, a ras-like GTP-binding protein associated with the Golgi complex.. Goud B, Yang C, Roa M, Martinez O, Mayau V., ...
  https://pub.uni-bielefeld.de/publication/2374443
*  DMXL2 Gene - GeneCards | DMXL2 Protein | DMXL2 Antibody
Protein Coding), Dmx Like 2, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The ... Rabconnectin-3, a novel protein that binds both GDP/GTP exchange protein and GTPase-activating protein for Rab3 small G protein ... Protein Symbol:. Q8TDJ6-DMXL2_HUMAN. Recommended name:. DmX-like protein 2. Protein Accession:. Q8TDJ6. Secondary Accessions: * ... Protein Expression for DMXL2 Gene. See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB ...
  https://www.genecards.org/cgi-bin/carddisp.pl?gene=DMXL2
*  WikiGenes - RAB3GAP1 - RAB3 GTPase activating protein subunit 1...
A novel rabconnectin-3-binding protein that directly binds a GDP/GTP exchange protein for Rab3A small G protein implicated in ... Rab3 GEP stimulates the conversion of the GDP-bound inactive form to the GTP-bound active form, whereas Rab3 GAP stimulates the ... Therefore, the Rab3-GAP-binding site involves the switch I region of Rab3 and overlaps with the Rabphilin-binding domain [5]. ... Furthermore, Rabphilin, a putative target of Rab3, inhibited the activity of Rab3-GAP on Rab3 [5]. ...
  https://www.wikigenes.org/e/gene/e/22930.html
*  Plus it
... inducing neurodegeneration in glutaminergic interneurons by expressing a mutated GTP-binding protein Gαs (nuIs5 [Pglr-1::GFP; P ... I, J, Pan-neuronal expression of a GFP-tagged synaptic protein RAB-3 GTPase (I) and APL-1 (J) using the rab-3 promoter. K, L, ... Prab-3::GFP::rab-3] transgenic animals in which a GFP-tagged RAB-3 GTPase is expressed under the rab-3 promoter; these animals ... Prab-3::apl-1 cDNA::GFP], ynIs112 [Prab-3::apl-1 cDNA::GFP], ynIs91 [Prab-3::apl-1 cDNA::GFP], ynIs12 [Psnb-1::apl-1 cDNA], ...
  http://www.jneurosci.org/content/32/30/10156
*  TumorPortal
This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with ... RAB3 GTPase activating protein subunit 1 (catalytic). External References: Wikipedia GeneCards HUGO COSMIC Google Scholar NCBI ... This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non- ... catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. ...
  http://www.tumorportal.org/view?geneSymbol=RAB3GAP1
*  DMXL2 - Wikipedia
... a novel protein that binds both GDP/GTP exchange protein and GTPase-activating protein for Rab3 small G protein family". ... "A novel rabconnectin-3-binding protein that directly binds a GDP/GTP exchange protein for Rab3A small G protein implicated in ... Dmx-like 2 is a protein that in humans is encoded by the DMXL2 gene. This gene encodes a protein with 12 WD domains. Proteins ... Research has indicated that this is a result of altered function of CNS synapses (in which the protein product of Dmxl2 is ...
  https://en.wikipedia.org/wiki/DMXL2
*  RAB3B - Wikipedia
Zahraoui A, Touchot N, Chardin P, Tavitian A (1989). "The human Rab genes encode a family of GTP-binding proteins related to ... 1994). "Expression and polarized targeting of a rab3 isoform in epithelial cells". J. Cell Biol. 125 (3): 583-94. doi:10.1083/ ... Ras-related protein Rab-3B is a protein that in humans is encoded by the RAB3B gene. RAB3B has been shown to interact with ... 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. doi:10.1038 ...
  https://en.wikipedia.org/wiki/RAB3B
*  Plus it
... and GTP-bound Rab11b is unexpected in view of the GTP-dependent regulation of Rab proteins (Segev, 2001; Zerial and McBride, ... Among the Rab proteins tested, we found that besides the previously described Rab3 proteins, only members of the Rab11 family ( ... The differential potency of GTP-bound versus GDP-bound Rab11b suggests that the GTP- and GDP-bound forms of Rab11b have ... by a partially inactive GTP-bound form if the GTP-bound form was expressed at 10 times higher levels than the GDP-bound form) ...
  http://www.jneurosci.org/content/23/33/10531
*  Plus it
1994) GTP cleavage by the small GTP-binding protein Rab3A is associated with exocytosis of synaptic vesicles induced by alpha- ... 1999) High affinity Rab3 binding is dispensable for Rabphilin-dependent potentiation of stimulated secretion. J Cell Sci 112: ... Given the interaction between Rab3a and rabphilin, we investigated whether the absence of the small GTP-binding protein has an ... 1991) A small GTP-binding protein dissociates from synaptic vesicles during exocytosis. Nature 349:79-81. ...
  http://www.jneurosci.org/content/21/15/5473
*  Frontiers | Molecular mechanisms driving homeostatic plasticity of neurotransmitter release | Frontiers in Cellular Neuroscience
These proteins turned out to be major presynaptic substrates for remodeling during homeostatic plasticity. Finally, we discuss ... These proteins turned out to be major presynaptic substrates for remodeling during homeostatic plasticity. Finally, we discuss ... We particularly focus on the role of presynaptic scaffolding proteins, which functionally and spatially organize synaptic ... We particularly focus on the role of presynaptic scaffolding proteins, which functionally and spatially organize synaptic ...
  https://www.frontiersin.org/articles/10.3389/fncel.2013.00244/full
*  List of MeSH codes (D08) - Wikipedia
... rab2 gtp-binding protein MeSH D08.811.277.040.330.300.400.400.100 --- rab3 gtp-binding proteins MeSH D08.811.277.040.330.300. ... gtp-binding protein alpha subunit, gi2 MeSH D08.811.277.040.330.300.200.100.300 --- gtp-binding protein alpha subunits, gq-g11 ... gtp-binding protein alpha subunits, g12-g13 MeSH D08.811.277.040.330.300.200.100.200 --- gtp-binding protein alpha subunits, gi ... ran gtp-binding protein MeSH D08.811.277.040.330.300.400.475 --- rap gtp-binding proteins MeSH D08.811.277.040.330.300.400.475. ...
  https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D08)
*  Rab3d - Ras-related protein Rab-3D - Mus musculus (Mouse) - Rab3d gene & protein
Protein transport. Probably involved in vesicular traffic (By similarity). May be involved in the insulin-induced exocytosis of ... "Rim1 and rabphilin-3 bind Rab3-GTP by composite determinants partially related through N-terminal alpha-helix motifs.". Wang X. ... GTP binding Source: UniProtKB-KW. *GTP-dependent protein binding Source: MGI ,p>Inferred from Physical Interaction,/p> ,p> ... View protein in InterPro. IPR027417. P-loop_NTPase. IPR037872. Rab3. IPR005225. Small_GTP-bd_dom. IPR001806. Small_GTPase. ...
  http://www.uniprot.org/uniprot/P35276
*  RAB3A - Wikipedia
Zahraoui A, Touchot N, Chardin P, Tavitian A (1989). "The human Rab genes encode a family of GTP-binding proteins related to ... Clabecq A, Henry JP, Darchen F (2000). "Biochemical characterization of Rab3-GTPase-activating protein reveals a mechanism ... Geppert M, Goda Y, Stevens CF, Südhof TC (1997). "The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle ... "Characterization of the interaction of the monomeric GTP-binding protein Rab3a with geranylgeranyl transferase II". Eur. J. ...
  https://en.wikipedia.org/wiki/RAB3A
*  RAB3C - Wikipedia
Uphues I, Chern Y, Eckel J (Dec 1995). "Insulin-dependent translocation of the small GTP-binding protein rab3C in cardiac ... Schlüter OM, Khvotchev M, Jahn R, Südhof TC (Oct 2002). "Localization versus function of Rab3 proteins. Evidence for a common ... Ras-related protein Rab-3C is a protein that in humans is encoded by the RAB3C gene. Rab3C has been show to interact with ZWINT ... "A unique residue in rab3c determines the interaction with novel binding protein Zwint-1". FEBS Letters. 582 (19): 2838-42. doi: ...
  https://en.wikipedia.org/wiki/RAB3C
*  List of MeSH codes (D12.776.476) - Wikipedia
... rab1 gtp-binding proteins MeSH D12.776.476.525.400.050 -- rab2 gtp-binding protein MeSH D12.776.476.525.400.100 -- rab3 gtp- ... rac gtp-binding proteins MeSH D12.776.476.525.700.100.100 -- rac1 gtp-binding protein MeSH D12.776.476.525.700.200 -- rhoa gtp- ... rab3a gtp-binding protein MeSH D12.776.476.525.400.150 -- rab4 gtp-binding proteins MeSH D12.776.476.525.400.200 -- rab5 gtp- ... gtp-binding protein alpha subunits, g12-g13 MeSH D12.776.476.375.100.200 -- gtp-binding protein alpha subunits, gi-go MeSH ...
  https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D12.776.476)
*  CysLT2 Receptors - Page 2 - How NF-B is activated: the role of the IB kinase (IKK) complex
... whereas in a GTP-bound condition they are capable to mediate downstream results by communicating with joining protein known to ... RAB3Distance1 and RAB3Distance2 had been characterized as developing a complicated with Distance activity towards Rab3 isoforms ... to GTP or GDP. It can be believed that in a GDP-bound condition they are sedentary mainly, ... Without TBC1Chemical20-triggered RAB18 GTP-hydrolysis at the Er selvf?lgelig, the small percentage of the proteins that is GDP- ...
  http://cancercurehere.com/?cat=107&paged=2
*  RAB3GAP2 Gene - GeneCards | RBGPR Protein | RBGPR Antibody
Protein Coding), RAB3 GTPase Activating Non-Catalytic Protein Subunit 2, including: function, proteins, disorders, pathways, ... Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and ... GO annotations related to this gene include protein heterodimerization activity and Rab GTPase binding. ... Protein Symbol:. Q9H2M9-RBGPR_HUMAN. Recommended name:. Rab3 GTPase-activating protein non-catalytic subunit Protein Accession: ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=RAB3GAP2&ortholog_desc=all&rf=/home/genecards/current/website/carddisp.pl