*  Squaring up to DNA: pentapeptide repeat proteins and DNA mimicry | SpringerLink
Drlica K, Zhao X (1997) DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev 61(3):377-392PubMedCentral ... Wang M, Guo Q, Xu X, Wang X, Ye X, Wu S, Hooper DC, Wang M (2009) New plasmid-mediated quinolone resistance gene, qnrC, found ... Hata M, Suzuki M, Matsumoto M, Takahashi M, Sato K, Ibe S, Sakae K (2005) Cloning of a novel gene for quinolone resistance from ... Tran JH, Jacoby GA (2002) Mechanism of plasmid-mediated quinolone resistance. Proc Natl Acad Sci U S A 99(8):5638-5642. doi: ...
  https://link.springer.com/article/10.1007/s00253-014-6151-3
*  Quinolones - A Powerful Friend if Used Sparingly | AskDrMarisela.com
Quinolones - A Powerful Friend if Used Sparingly. Posted on March 20, 2015. by Marisela ... The quinolones work by inhibiting the synthesis of bacterial DNA, a process which results in bacterial cell death. These ... The quinolone antibiotics should not be given to pregnant females or children, as they can cause cartilage damage. Additionally ... Quinolones are associated with a variety of significant complications, including: A) development of clostridium difficile ...
  http://www.askdrmarisela.com/quinolones-a-powerful-friend-if-used-sparingly/
*  Quinolone antibiotic - Wikipedia
Andriole, VT The Quinolones. Academic Press, 1989. *^ Andersson MI, MacGowan AP (2003). "Development of the quinolones". ... Quinolone antibiotic at Curlie (based on DMOZ). *Healthcare-associated Infections (HAIs)- Quinolones and the Clinical ... Norris, S; Mandell, GL (1988). "The quinolones: history and overview". The quinolones: history and overview. San Diego: ... Although not formally a quinolone, nalidixic acid is considered the first quinolone drug. It was introduced in 1962 for ...
  https://en.wikipedia.org/wiki/Adverse_effects_of_fluoroquinolones
*  Quinolones and the Clinical Laboratory | HAI | CDC
What are quinolones?. Quinolones are antimicrobial agents effective in the treatment of selected community-acquired and ... Resistance to quinolones limits drug selection for treatment of many infections.. *Organisms resistant to quinolones often are ... Quinolone activity: Early quinolones, such as nalidixic acid, had poor systemic distribution and limited activity and were used ... What organisms can be resistant to quinolones?. Resistance to quinolones has been reported in a variety of important bacterial ...
  https://www.cdc.gov/hai/settings/lab/quinolones-clinical-laboratory.html
*  Overview of Quinolones (Example) - MindMeister
Overview of Quinolones, General information, Mechanism of action, Pharmacokinetics, Classification, Therapeutic use, Adverse ... Overview of Quinolones. by Mohammed Haneef 1. General information. 1.1. Synthetic antimicrobial agents. 1.2. First quinolone ... treated by quinolones. 5.4. Respiratory tract infections. 5.4.1. treated by respiratory fluroquinolones. 5.4.1.1. gemifloxacin ...
  https://www.mindmeister.com/164425379/overview-of-quinolones
*  Interactions between Insulin Regular Human Injection and antidiabetic-agents-selected-quinolones
... provides information about interactions between Insulin Regular Human Injection and antidiabetic-agents-selected-quinolones. ... Antidiabetic Agents/Selected Quinolones. This information is generalized and not intended as specific medical advice. Consult ... Using some quinolone antibiotics with your diabetes medicine may make your blood sugar too low. ...
  https://www.webmd.com/drugs/2/drug-5233/insulin-regular-human-injection/details/list-interaction-details/dmid-1442/dmtitle-antidiabetic-agents-selected-quinolones/intrtype-drug
*  The Quinolones, Book by Vincent T. Andriole (Hardcover) | chapters.indigo.ca
Buy the Hardcover Book The Quinolones by Vincent T. Andriole at Indigo.ca, Canada's largest bookstore. + Get Free Shipping on ... Use of the Quinolones in Sexually Transmitted Diseases. Treatment of Respiratory Infections with Quinolones. Use of Quinolones ... Use of the Quinolones in Treatment of Bacterial Meningitis. Use of the Quinolones in Immunocompromised Patients. Use of the ... The Quinolones: History and Overview. Chemistry and Mechanism of Action of the Quinolone Antibacterials. Comparative In-Vitro ...
  https://www.chapters.indigo.ca/en-ca/books/the-quinolones/9780120595174-item.html
*  ASMscience | Effects of Quinolones on
A plethora of quinolone effects on specific components of the immune response have been reviewed. Downregulation of cytokine ... Effects of the quinolones on the immune system, p. 519-526. In D. C. Hooper, and J. S. Wolfson (ed.), Quinolone Antimicrobial ... Home / Books / Quinolone Antimicrobial Agents, Third Edition / Chapter Chapter 30 : Effects of Quinolones on the Immune System ... Effects of Quinolones on the Immune System, p 467-473. In Hooper D, Rubinstein E (ed), Quinolone Antimicrobial Agents, Third ...
  http://www.asmscience.org/content/book/10.1128/9781555817817.chap30
*  Activity of the newer quinolones against Chlamydia trachomatis. | Sexually Transmitted Infections
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center's RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...
  http://sti.bmj.com/content/60/5/350.1
*  Addition of quinolones to hospital formularies changes pneumonia treatment | Managed Care magazine
Simultaneously, systemic quinolone therapy rose from 28 percent in 1998 to over 56 percent in 2002. In the quinolone market, ... Most cephalosporins, except for Rocephin, need to be administered every eight hours, while the newer quinolones are ... the introduction of quinolones to hospital formularies has eroded the cephalosporin market share considerably in the past few ...
  http://managedcaremag.com/archives/2003/2/addition-quinolones-hospital-formularies-changes-pneumonia-treatment
*  Interactions between Calcium Carbonate And Calcium Citrate-Magnesium Oxide Oral and selected-oral-cations-selected-oral...
... between Calcium Carbonate And Calcium Citrate-Magnesium Oxide Oral and selected-oral-cations-selected-oral-quinolones. ... Selected Oral Quinolones/Selected Oral Cations. This information is generalized and not intended as specific medical advice. ...
  https://www.webmd.com/drugs/2/drug-163244/calcium-carbonate-and-calcium-citrate-magnesium-oxide-oral/details/list-interaction-details/dmid-2076/dmtitle-selected-oral-cations-selected-oral-quinolones/intrtype-drug
*  Macrolides, quinolones and amoxicillin/clavulanate for chronic bronchitis: a meta-analysis | European Respiratory Society
A/C was compared with quinolones in four RCTs 24, 32-34 and with macrolides in eight RCTs 35-42. In detail, the quinolone ... Thus, 19 RCTs that compared macrolides with quinolones (n = 8) 24-31 and A/C with quinolones (n = 4) 24, 32-34 or macrolides (n ... b) Amoxicillin/clavulanate (A/C) versus quinolones (0.86 (0.55-1.34)), 0.20-1.00 favours quinolones and 1.00-4.97 favours A/C. ... Macrolides versus quinolones (odds ratio 0.94 (95% confidence interval 0.73-1.21)), 0.30-1.00 favours quinolones and 1.00-3.38 ...
  http://erj.ersjournals.com/content/29/6/1127
*  British Library EThOS: Attempts to synthesise substituted quinolones as antibiotic targets using solid phase techniques
Quinolones, and especially fluoroquinolones, are one of the largest classes of antibacterial agents used worldwide. Thus, the ... In addition, quinolone derivative analogues were synthesised and investigated as amylolytic agents towards some Aspergillus ... The Vilsmeier approach had limited applicability in quinolone synthesis. On the other hand, the Vilsmeier reaction with oxalyl ... The 7-bromoquinolone analogue, 7-bromo-6-(N-benzylpiperazin-1-yl)-4-oxo-3- quinolone carboxylic acid 91 showed the high potency ...
  http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.592878
*  1-hydroxy-2-dodecyl-4(1H)quinolone | C21H31NO2 - PubChem
... quinolone , C21H31NO2 , CID 600305 - structure, chemical names, physical and chemical properties, classification, patents, ...
  https://pubchem.ncbi.nlm.nih.gov/compound/600305
*  British Library EThOS: Molecular interactions between DNA gyrase and the quinolone antibacterials
The acquisition of quinolone-resistance in E. coli and Salmonella has also been investigated. Firstly, part of gyrA of S. ... The quinolone antibacterials have previously been shown to "poison" DNA gyrase of Escherichia coli, resulting in rapid ... Following on from the finding that the complex of quinolone and gyrase on DNA results in truncated mRNAs in vitro, the results ... It has also been shown that the newer more potent quinolone drugs such as ciprofloxacin and ofloxacin have an additional effect ...
  http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.642096
*  Risk Factors for Quinolone Resistance Among ESBL Producing Klebsiella Species - Full Text View - ClinicalTrials.gov
Risk Factors for Quinolone Resistance Among ESBL Producing Klebsiella Species. This study is ongoing, but not recruiting ... Risk Factors for Quinolone Resistance Among Extended-Spectrum Beta-Lactamase-Producing Klebsiella Species. ... This proposed study aims to document the risk factors for quinolone resistance in bloodstream isolates of Klebsiella species. ... This proposed study aims to document the risk factors for quinolone resistance in bloodstream isolates of Klebsiella species. ...
  https://clinicaltrials.gov/ct2/show/NCT00518661?cond=%22Klebsiella%22&rank=2
*  Plasmid mediated quinolone resistance (PMQR) is rare, but widespread found in European farm animals - WUR
However, in recent years, this type of quinolone resistance was more frequently observed in animals to which more quinolones ... Plasmid mediated quinolone resistance (PMQR) is rare, but widespread found in European farm animals. A new type of ... Plasmid mediated quinolone resistance (PMQR) is rare, but widespread found in European farm animals ... In his research, Veldman describes the first Salmonella and E. coli bacteria with transferable quinolone resistance in farm ...
  https://www.wur.nl/nl/activiteit/Plasmid-mediated-quinolone-resistance-PMQR-is-rare-but-widespread-found-in-European-farm-animals.htm
*  Molecules | Free Full-Text | Chemistry of Nitroquinolones and Synthetic Application to Unnatural 1-Methyl-2-quinolone...
8-dinitro-2-quinolones upon treatment with nucleophilic reagents. Contrary to this, 1-methyl-3,6-dinitro-2-quinolone (3,6-DNQ) ... Among nitroquinolones, 1-methyl-3,6,8-trinitro-2-quinolone (TNQ) exhibits unusual reactivity favoring region-selective cine- ... The 1-methyl-2-quinolone (MeQone) framework is often found in alkaloids and recently attention was drawn to unnatural MeQone ... 8-dinitro-2-quinolones upon treatment with nucleophilic reagents. Contrary to this, 1-methyl-3,6-dinitro-2-quinolone (3,6-DNQ) ...
  http://www.mdpi.com/1420-3049/15/8/5174
*  Targeting quinolone- and aminocoumarin-resistant bacteria with new gyramide analogs that inhibit DNA gyrase - MedChemComm (RSC...
Targeting quinolone- and aminocoumarin-resistant bacteria with new gyramide analogs that inhibit DNA gyrase K. A. Hurley, T. M ... Targeting quinolone- and aminocoumarin-resistant bacteria with new gyramide analogs that inhibit DNA gyrase ...
  http://pubs.rsc.org/en/content/articlelanding/2017/md/c7md00012j
*  Spectrophotometric Determination of Quinolones by Charge Transfer Complexation with Chloranilic Acid: Synthesis and...
Spectrophotometric Determination of Quinolones by Charge Transfer Complexation with Chloranilic Acid: Synthesis and ... A simple and sensitive spectrophotometric method has been described for the assay of quinolones in bulk drug and in ... The developed method is based on the formation of colored charge transfer complexes of quinolones with chloranilic acid in ... Spectrophotometric Determination of Quinolones by Charge Transfer Complexation with Chloranilic Acid: Synthesis and ...
  https://www.omicsonline.org/peer-reviewed/spectrophotometric-determination-of-quinolones-by-charge-transfercomplexation-with-chloranilic-acid-synthesis-and-characterization-18849.html
*  4-Quinolone - Wikipedia
It and 2-quinolone are the two most important parent (meaning simplified) quinolones. 4-Quinolone exists in equilibrium with a ... The hydroxyquinolines tautomerize to the quinolones. Andriole, VT The Quinolones. Academic Press, 1989. Shi, Pengfei; Wang, ... the 4-quinolone antibiotics represent a large class of important drugs. The chemical synthesis of quinolones often involves ... 4-Quinolone is an organic compound derived from quinoline. ... 4-Quinolone is of little intrinsic value but its derivatives, ...
  https://en.wikipedia.org/wiki/4-Quinolone
*  Investigations into quinolone and fluoroquinolone resistance in Salmonella enterica - Enlighten: Theses
Plasmid-mediated quinolone resistance has recently been identified in isolates of S. enterica in a number of countries at low ... Murray, Angela (2009) Investigations into quinolone and fluoroquinolone resistance in Salmonella enterica. MSc(R) thesis, ... all other isolates examined were resistant to the quinolone nalidixic acid. Resistance to fluoroquinolones was rare during this ... methods of Plasmid Profile Analysis and Pulsed Field Gel Electrophoresis and levels of resistance were determined for quinolone ...
  http://theses.gla.ac.uk/1499/
*  2-Quinolone - Wikipedia
The isomer 4-quinolone is the parent of a large class of quinolone antibiotics. Tashima, Toshihiko (2015). "The structural use ... 2-Quinolone is an organic compound related structurally to quinoline. It is the majority tautomer in equilibrium with 2- ...
  https://en.wikipedia.org/wiki/2-Quinolone