*  Microbiology Society Journals | Detection of mutations in the gyrA and parC genes in Escherichia coli isolates carrying plasmid...
The quinolone resistance-determining regions (QRDRs) of the gyrA and parC genes were analysed for mutations in 55 isolates ... the prevalence of oqxAB had significant Spearman correlation coefficients in relation to the MICs of all four tested quinolones ... demonstrated that the number of mutations in QRDRs of gyrA and/or parC was significantly associated with the MICs of quinolones ... the prevalence of plasmid-mediated quinolone resistance (PMQR) was investigated in 495 Escherichia coli isolates from diseased ...
  http://jmm.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.043307-0
*  Quinolones - A Powerful Friend if Used Sparingly | AskDrMarisela.com
Quinolones - A Powerful Friend if Used Sparingly. Posted on March 20, 2015. by Marisela ... The quinolones work by inhibiting the synthesis of bacterial DNA, a process which results in bacterial cell death. These ... The quinolone antibiotics should not be given to pregnant females or children, as they can cause cartilage damage. Additionally ... Quinolones are associated with a variety of significant complications, including: A) development of clostridium difficile ...
  http://www.askdrmarisela.com/quinolones-a-powerful-friend-if-used-sparingly/
*  Overview of Quinolones (Example) - MindMeister
Overview of Quinolones, General information, Mechanism of action, Pharmacokinetics, Classification, Therapeutic use, Adverse ... Overview of Quinolones. by Mohammed Haneef 1. General information. 1.1. Synthetic antimicrobial agents. 1.2. First quinolone ... treated by quinolones. 5.4. Respiratory tract infections. 5.4.1. treated by respiratory fluroquinolones. 5.4.1.1. gemifloxacin ...
  https://www.mindmeister.com/164425379/overview-of-quinolones
*  Interactions between Insulin Regular Human Injection and antidiabetic-agents-selected-quinolones
... provides information about interactions between Insulin Regular Human Injection and antidiabetic-agents-selected-quinolones. ... Antidiabetic Agents/Selected Quinolones. This information is generalized and not intended as specific medical advice. Consult ... Using some quinolone antibiotics with your diabetes medicine may make your blood sugar too low. ...
  https://www.webmd.com/drugs/2/drug-5233/insulin-regular-human-injection/details/list-interaction-details/dmid-1442/dmtitle-antidiabetic-agents-selected-quinolones/intrtype-drug
*  The Quinolones, Book by Vincent T. Andriole (Hardcover) | chapters.indigo.ca
Buy the Hardcover Book The Quinolones by Vincent T. Andriole at Indigo.ca, Canada's largest bookstore. + Get Free Shipping on ... Use of the Quinolones in Sexually Transmitted Diseases. Treatment of Respiratory Infections with Quinolones. Use of Quinolones ... Use of the Quinolones in Treatment of Bacterial Meningitis. Use of the Quinolones in Immunocompromised Patients. Use of the ... The Quinolones: History and Overview. Chemistry and Mechanism of Action of the Quinolone Antibacterials. Comparative In-Vitro ...
  https://www.chapters.indigo.ca/en-ca/books/the-quinolones/9780120595174-item.html
*  Toxicity of Quinolones | Springer for Research & Development
Quinolone binding to DNA is mediated by magnesium ions. Proc Natl Acad Sci USA 1992; 89: 9671-5PubMedCrossRefGoogle Scholar ... Quinolone-induced cartilage lesions are not reversible in rats. Arch Toxicol 1996; 70: 474-81PubMedCrossRefGoogle Scholar ... Toxicity of quinolone antimicrobial agents. J Toxicol Environ Health 1995; 45: 1-45PubMedCrossRefGoogle Scholar ... Stahlmann R. Safety profile of the quinolones. J Antimicrob Chemother 1990; 26 Suppl. D: 31-44PubMedCrossRefGoogle Scholar ...
  https://rd.springer.com/article/10.2165/00003495-199958002-00007
*  Activity of the newer quinolones against Chlamydia trachomatis. | Sexually Transmitted Infections
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center's RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...
  http://sti.bmj.com/content/60/5/350.1
*  Addition of quinolones to hospital formularies changes pneumonia treatment | Managed Care magazine
Simultaneously, systemic quinolone therapy rose from 28 percent in 1998 to over 56 percent in 2002. In the quinolone market, ... Most cephalosporins, except for Rocephin, need to be administered every eight hours, while the newer quinolones are ... the introduction of quinolones to hospital formularies has eroded the cephalosporin market share considerably in the past few ...
  http://managedcaremag.com/archives/2003/2/addition-quinolones-hospital-formularies-changes-pneumonia-treatment
*  Interactions between Calcium Carbonate And Calcium Citrate-Magnesium Oxide Oral and selected-oral-cations-selected-oral...
... between Calcium Carbonate And Calcium Citrate-Magnesium Oxide Oral and selected-oral-cations-selected-oral-quinolones. ... Selected Oral Quinolones/Selected Oral Cations. This information is generalized and not intended as specific medical advice. ...
  https://www.webmd.com/drugs/2/drug-163244/calcium-carbonate-and-calcium-citrate-magnesium-oxide-oral/details/list-interaction-details/dmid-2076/dmtitle-selected-oral-cations-selected-oral-quinolones/intrtype-drug
*  Macrolides, quinolones and amoxicillin/clavulanate for chronic bronchitis: a meta-analysis | European Respiratory Society
A/C was compared with quinolones in four RCTs 24, 32-34 and with macrolides in eight RCTs 35-42. In detail, the quinolone ... Thus, 19 RCTs that compared macrolides with quinolones (n = 8) 24-31 and A/C with quinolones (n = 4) 24, 32-34 or macrolides (n ... b) Amoxicillin/clavulanate (A/C) versus quinolones (0.86 (0.55-1.34)), 0.20-1.00 favours quinolones and 1.00-4.97 favours A/C. ... Macrolides versus quinolones (odds ratio 0.94 (95% confidence interval 0.73-1.21)), 0.30-1.00 favours quinolones and 1.00-3.38 ...
  http://erj.ersjournals.com/content/29/6/1127
*  British Library EThOS: Attempts to synthesise substituted quinolones as antibiotic targets using solid phase techniques
Quinolones, and especially fluoroquinolones, are one of the largest classes of antibacterial agents used worldwide. Thus, the ... In addition, quinolone derivative analogues were synthesised and investigated as amylolytic agents towards some Aspergillus ... The Vilsmeier approach had limited applicability in quinolone synthesis. On the other hand, the Vilsmeier reaction with oxalyl ... The 7-bromoquinolone analogue, 7-bromo-6-(N-benzylpiperazin-1-yl)-4-oxo-3- quinolone carboxylic acid 91 showed the high potency ...
  http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.592878
*  1-hydroxy-2-dodecyl-4(1H)quinolone | C21H31NO2 - PubChem
... quinolone , C21H31NO2 , CID 600305 - structure, chemical names, physical and chemical properties, classification, patents, ...
  https://pubchem.ncbi.nlm.nih.gov/compound/600305
*  British Library EThOS: Molecular interactions between DNA gyrase and the quinolone antibacterials
The acquisition of quinolone-resistance in E. coli and Salmonella has also been investigated. Firstly, part of gyrA of S. ... The quinolone antibacterials have previously been shown to "poison" DNA gyrase of Escherichia coli, resulting in rapid ... Following on from the finding that the complex of quinolone and gyrase on DNA results in truncated mRNAs in vitro, the results ... It has also been shown that the newer more potent quinolone drugs such as ciprofloxacin and ofloxacin have an additional effect ...
  http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.642096
*  Risk Factors for Quinolone Resistance Among ESBL Producing Klebsiella Species - Full Text View - ClinicalTrials.gov
Risk Factors for Quinolone Resistance Among ESBL Producing Klebsiella Species. This study is ongoing, but not recruiting ... Risk Factors for Quinolone Resistance Among Extended-Spectrum Beta-Lactamase-Producing Klebsiella Species. ... This proposed study aims to document the risk factors for quinolone resistance in bloodstream isolates of Klebsiella species. ... This proposed study aims to document the risk factors for quinolone resistance in bloodstream isolates of Klebsiella species. ...
  https://clinicaltrials.gov/ct2/show/NCT00518661?cond=%22Klebsiella%22&rank=2
*  Spectrophotometric Determination of Quinolones by Charge Transfer Complexation with Chloranilic Acid: Synthesis and...
Spectrophotometric Determination of Quinolones by Charge Transfer Complexation with Chloranilic Acid: Synthesis and ... A simple and sensitive spectrophotometric method has been described for the assay of quinolones in bulk drug and in ... The developed method is based on the formation of colored charge transfer complexes of quinolones with chloranilic acid in ... Spectrophotometric Determination of Quinolones by Charge Transfer Complexation with Chloranilic Acid: Synthesis and ...
  https://www.omicsonline.org/peer-reviewed/spectrophotometric-determination-of-quinolones-by-charge-transfercomplexation-with-chloranilic-acid-synthesis-and-characterization-18849.html
*  Investigations into quinolone and fluoroquinolone resistance in Salmonella enterica - Enlighten: Theses
Plasmid-mediated quinolone resistance has recently been identified in isolates of S. enterica in a number of countries at low ... Murray, Angela (2009) Investigations into quinolone and fluoroquinolone resistance in Salmonella enterica. MSc(R) thesis, ... all other isolates examined were resistant to the quinolone nalidixic acid. Resistance to fluoroquinolones was rare during this ... methods of Plasmid Profile Analysis and Pulsed Field Gel Electrophoresis and levels of resistance were determined for quinolone ...
  http://theses.gla.ac.uk/1499/
*  4-Quinolone - Wikipedia
It and 2-quinolone are the two most important parent (meaning simplified) quinolones. 4-Quinolone exists in equilibrium with a ... The hydroxyquinolines tautomerize to the quinolones. Andriole, VT The Quinolones. Academic Press, 1989. Shi, Pengfei; Wang, ... the 4-quinolone antibiotics represent a large class of important drugs. The chemical synthesis of quinolones often involves ... 4-Quinolone is an organic compound derived from quinoline. ... 4-Quinolone is of little intrinsic value but its derivatives, ...
  https://en.wikipedia.org/wiki/4-Quinolone
*  Quinolone antibiotic - Wikipedia
Quinolone antibiotic at Curlie (based on DMOZ) Healthcare-associated Infections (HAIs)- Quinolones and the Clinical Laboratory ... Although not formally a quinolone, nalidixic acid is considered the first quinolone drug. It was introduced in 1962 for ... Norris, S; Mandell, GL (1988). "The quinolones: history and overview". The quinolones: history and overview. San Diego: ... VT The Quinolones. Academic Press, 1989. Andersson MI, MacGowan AP (2003). "Development of the quinolones". Journal of ...
  https://en.wikipedia.org/wiki/Quinolone_antibiotic
*  2-Quinolone - Wikipedia
The isomer 4-quinolone is the parent of a large class of quinolone antibiotics. Tashima, Toshihiko (2015). "The structural use ... 2-Quinolone is an organic compound related structurally to quinoline. It is the majority tautomer in equilibrium with 2- ...
  https://en.wikipedia.org/wiki/2-Quinolone
*  US Patent # 8,129,533. Method for production of quinolone-containing lyophilized preparation - Patents.com
The present invention is directed to a lyophilized preparation which contains a synthetic quinolone antibacterial compound and ... When a quinolone compound is prepared into a lyophilized preparation through the method of the present invention, the quinolone ... In formula (1), R.sup.1 and R.sup.2 may be linked together to form a ring including a part of the quinolone skeleton. The thus- ... X.sup.2 and the aforementioned R.sup.1 may be linked together to form a ring including a part of the quinolone skeleton, and ...
  http://patents.com/us-8129533.html
*  Quinolones | definition of quinolones by Medical dictionary
... quinolones explanation free. What is quinolones? Meaning of quinolones medical term. What does quinolones mean? ... Looking for online definition of quinolones in the Medical Dictionary? ... quinolones. Also found in: Dictionary.. Related to quinolones: ciprofloxacin, Aminoglycosides quin·o·lones. (kwin'ō-lōnz), A ... Quinolones , definition of quinolones by Medical dictionary https://medical-dictionary.thefreedictionary.com/quinolones ...
  http://medical-dictionary.thefreedictionary.com/quinolones
*  Quinolone-Based Antibacterial Chemoprophylaxis in Neutropenic Patients: Effect of Augmented Gram-Positive Activity on...
Quinolone-Based Antibacterial Chemoprophylaxis in Neutropenic Patients: Effect of Augmented Gram-Positive Activity on ... Quinolone-Based Antibacterial Chemoprophylaxis in Neutropenic Patients: Effect of Augmented Gram-Positive Activity on ... Quinolone-based antibacterial chemoprophylaxis protected patients from aerobic gram-negative bacillary infections. Augmentation ... To determine whether augmented quinolone-based antibacterial prophylaxis in neutropenic patients with cancer reduces infections ...
  http://annals.org/aim/article-abstract/709847/quinolone-based-antibacterial-chemoprophylaxis-neutropenic-patients-effect-augmented-gram-positive
*  Biotic inactivation of the Pseudomonas aeruginosa quinolone signal molecule - Nottingham ePrints
To identify bacteria capable of inactivating the QS signal molecule 2-heptyl-3- hydroxy-4(1H)-quinolone (PQS), a minimal medium ... Biotic inactivation of the Pseudomonas aeruginosa quinolone signal molecule. Environmental Microbiology, 17 (11). pp. 4352-4365 ...
  http://eprints.nottingham.ac.uk/34902/