*  "Rare, highly pyrimethamine-resistant alleles of the Plasmodium falcipa" by S.J. Bates, P.A. Winstanley et al.
We used a yeast-expression system to identify rare, highly pyrimethamine-resistant alleles of dhfr in isolates from 5 African ... associated with increased risk of clinical failure of sulfadoxine-pyrimethamine (S/P). Molecular methods for surveillance of ... Rare, highly pyrimethamine-resistant alleles of the Plasmodium falciparum dihydrofolate reductase gene from 5 African sites ... We used a yeast-expression system to identify rare, highly pyrimethamine-resistant alleles of dhfr in isolates from 5 African ...
  https://ecommons.aku.edu/eastafrica_fhs_mc_pathol/77/
*  Pyrimethamine (Oral Route) Before Using - Mayo Clinic
Allergy to pyrimethamine or any ingredient in the medicine-pyrimethamine should not be used ... Information about this pyrimethamine-oral-route. Pregnancy Category. Explanation. All Trimesters. C. Animal studies have shown ... Pyrimethamine has been used in children and, in effective doses, has not been shown to cause different side effects or problems ... Pyrimethamine, especially in high doses, may cause blood problems. These problems may result in a greater chance of certain ...
  https://www.mayoclinic.org/drugs-supplements/pyrimethamine-oral-route/before-using/DRG-20065700?p=1
*  Sulphadoxine/pyrimethamine: an appropriate first-line alternative...: Ingenta Connect
Sulphadoxine/pyrimethamine: an appropriate first-line alternative for the treatment of uncomplicated falciparum malaria in ... Keywords: Ghana; children; chloroquine; drug resistance; malaria; randomized trial; sulphadoxine-pyrimethamine; treatment ... first-line drug for the treatment of uncomplicated falciparum malaria in Ghana and whether sulphadoxine/pyrimethamine (SP) ...
  http://www.ingentaconnect.com/content/bsc/tmih/2002/00000007/00000007/art00005
*  Pyrimethamine - For All Medical Treatment Options Explained, Visit CureCrowd
Pyrimethamine. Also Known As: Pyrimethamine, Daraprim. Pyrimethamine (Daraprim) is a medication used for protozoal infections. ... Pyrimethamine interferes with tetrahydrofolic acid synthesis from folic acid by inhibiting the enzyme dihydrofolate reductase ( ... Mutations in the malarial gene for dihydrofolate reductase may reduce the effectiveness of pyrimethamine.[2] These mutations ... Complete a survey on Pyrimethamine to help the CureCrowd community. If you have tried to treat this ailment, please complete ...
  https://www.curecrowd.com/treatments/pyrimethamine
*  pyrimethamine | Ligand page | IUPHAR/BPS Guide to PHARMACOLOGY
pyrimethamine ligand page. Quantitative data and detailed annnotation of the targets of licensed and experimental drugs. ...
  http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?tab=structure&ligandId=4800
*  A Study of Azithromycin Plus Pyrimethamine in the Treatment of a Brain Infection in Patients With AIDS - Full Text View -...
All patients also receive pyrimethamine. Folinic acid is also provided for as long as patients receive pyrimethamine. Patients ... A Study of Azithromycin Plus Pyrimethamine in the Treatment of a Brain Infection in Patients With AIDS. This study has been ... Pyrimethamine plus azithromycin for treatment of acute toxoplasmic encephalitis in patients with AIDS. Eur J Clin Microbiol ... Pyrimethamine. Leucovorin. Drug Evaluation. Drug Therapy, Combination. Encephalitis. Administration, Oral. Acquired ...
  https://clinicaltrials.gov/show/NCT00000966?order=52
*  The American Journal of Tropical Medicine and Hygiene | Toxicity Studies of Pyrimethamine (Daraprim1)
... no toxic effects which could be unequivocably attributed to pyrimethamine were observed. ... Summary The administration of pyrimethamine (Daraprim) to 81 men in doses of 25 mg. weekly for 6 months failed to produce toxic ... Toxicity Studies of Pyrimethamine (Daraprim 1) * Authors: Raymond J. Dern, Ernest Beutler, John Arnold, Allan Lorincz, Matthew ... The administration of pyrimethamine (Daraprim) to 81 men in doses of 25 mg. weekly for 6 months failed to produce toxic effects ...
  http://www.ajtmh.org/content/journals/10.4269/ajtmh.1955.4.217
*  Intermittent preventive therapy - Wikipedia
Efficacy of sulfadoxine-pyrimethamine for prevention of placental malaria in an area of Kenya with a high prevalence of malaria ... Sulfadoxine-pyrimethamine is the drug currently recommended by the WHO because of its safety and efficacy in pregnancy. Several ... Intermittent sulphadoxine-pyrimethamine to prevent severe anaemia secondary to malaria in pregnancy: a randomised placebo- ... Intermittent sulfadoxine-pyrimethamine in pregnancy: effectiveness against malaria morbidity in Blantyre, Malawi, in 1997-99. ...
  https://en.wikipedia.org/wiki/Intermittent_preventive_therapy
*  Pyrimethamine | The BMJ
Pyrimethamine. Br Med J 1956; 1 doi: https://doi.org/10.1136/bmj.1.4976.1170-a (Published 19 May 1956) Cite this as: Br Med J ...
  http://www.bmj.com/content/1/4976/1170.2
*  Sulfadoxine-Pyrimethamine Indo Farma - Drugs.com
A list of US medications equivalent to Sulfadoxine-Pyrimethamine Indo Farma is available on the Drugs.com website. ... Sulfadoxine-Pyrimethamine Indo Farma is a medicine available in a number of countries worldwide. ... Pyrimethamine. Pyrimethamine is reported as an ingredient of Sulfadoxine-Pyrimethamine Indo Farma in the following countries:. ... Sulfadoxine-Pyrimethamine Indo Farma. Sulfadoxine-Pyrimethamine Indo Farma may be available in the countries listed below. ...
  https://www.drugs.com/international/sulfadoxine-pyrimethamine-indo-farma.html
*  Sulfadoxine and Pyrimethamine
Brand of Sulfadoxine and Pyrimethamine TABLETS WARNING FATALITIES ASSOCIATED WITH THE ADMINISTRATION OF FANSIDAR HAVE OCCURRED ...
  http://www.egeneralmedical.com/rxlist00000471.html
*  Pyrimethamine And Sulfadoxine (Oral Route) Side Effects - Mayo Clinic
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:. ...
  http://www.mayoclinic.org/drugs-supplements/pyrimethamine-and-sulfadoxine-oral-route/side-effects/drg-20062761
*  Pyrimethamine ("Daraprim") in the Treatment of Vivax Malaria | The BMJ
Pyrimethamine ("Daraprim") in the Treatment of Vivax Malaria Br Med J 1953; 2 :258 ... Pyrimethamine ("Daraprim") in the Treatment of Vivax Malaria. Br Med J 1953; 2 doi: https://doi.org/10.1136/bmj.2.4830.258 ( ...
  http://www.bmj.com/content/2/4830/258
*  Fatal multisystemic toxicity associated with prophylaxis with pyrimethamine and sulfadoxine (Fansidar). | The BMJ
Fatal multisystemic toxicity associated with prophylaxis with pyrimethamine and sulfadoxine (Fansidar). Br Med J (Clin Res Ed) ... Fatal multisystemic toxicity associated with prophylaxis with pyrimethamine and sulfadoxine (Fansidar).. Br Med J (Clin Res Ed) ...
  http://www.bmj.com/content/290/6462/113.2
*  Artesunate+Sulfadoxine-Pyrimethamine for the Treatment of Uncomplicated Falciparum Malaria
artesunate plus sulfadoxine-pyrimethamine (AS+SP). Location. Provincial Malaria Control Centers (MRC). Maimana. Faryab. ... Artesunate+Sulfadoxine-Pyrimethamine for the Treatment of Uncomplicated Falciparum Malaria. 2014-08-27 03:14:00 , BioPortfolio ... The objective of the study is to assess the efficacy and safety of Artesunate/Sulfadoxine-Pyrimethamine (AS+SP) for the ... The purpose of this study is to compare the efficacy of sulfadoxine-pyrimethamine plus artesunate with that of sulfadoxine- ...
  https://www.bioportfolio.com/resources/trial/65389/Artesunate-Sulfadoxine-Pyrimethamine-for-the-Treatment-of-Uncomplicated-Falciparum-Malaria.html
*  Pyrimethamine and Sulfadoxine for Treatment of Autoimmune Lymphoproliferative Syndrome - Tabular View - ClinicalTrials.gov
Pyrimethamine and Sulfadoxine for Treatment of Autoimmune Lymphoproliferative Syndrome. The safety and scientific validity of ... Pyrimethamine and Sulfadoxine for Treatment of Autoimmune Lymphoproliferative Syndrome. Official Title ICMJE Pilot Study of ... Fansidar is a combination of two drugs, sulfadoxine and pyrimethamine, that is used to treat or prevent parasitic infections ... If you are receiving and requiring anti-folate drugs such as sulfonamides, trimethoprim, pyrimethamine and methotrexate will be ...
  https://clinicaltrials.gov/ct2/show/record/NCT00013689
*  "Oral lichenoid reactions during antimalarial prophylaxis with sulphadoxine-pyrimethamine combination" by Rosnah Binti...
Oral lichenoid reactions during antimalarial prophylaxis with sulphadoxine-pyrimethamine combination. Southeast Asian Journal ... "Oral lichenoid reactions during antimalarial prophylaxis with sulphadoxine-pyrimethamine combination" Southeast Asian Journal ...
  https://works.bepress.com/rosnah_zain/42/
*  Isospora belli Infection: Treatment with Pyrimethamine | Annals of Internal Medicine | American College of Physicians
They were treated successfully with pyrimethamine alone, 75 mg/d, and recurrence was prevented with daily pyrimethamine therapy ... Isospora belli Infection: Treatment with Pyrimethamine Louis M. Weiss, MD, MPH; David C. Perlman, MD; Jeffrey Sherman, MD; ... Weiss LM, Perlman DC, Sherman J, Tanowitz H, Wittner M. Isospora belli Infection: Treatment with Pyrimethamine. Ann Intern Med ... Twice-Weekly Maintenance Therapy with Sulfadiazine-Pyrimethamine To Prevent Recurrent Toxoplasmic Encephalitis in Patients with ...
  http://annals.org/aim/article-abstract/702590/isospora-belli-infection-treatment-pyrimethamine
*  Efficacy of Sulphadoxine-pyrimethamine and Artemisinin-containing Combination Therapy for Malaria - Full Text View -...
Drug: Sulfadoxine-pyrimethamine Drug: sulfadoxine-pyrimethamine plus artesunate Drug: lumefantrine plus artemether Behavioral: ... Pyrimethamine. Sulfadoxine. Fanasil, pyrimethamine drug combination. Amebicides. Antiprotozoal Agents. Antiparasitic Agents. ... Efficacy of Sulphadoxine-pyrimethamine and Artemisinin-containing Combination Therapy for Malaria. The safety and scientific ... This is an ongoing monitoring activity of efficacy of sulfadoxine-pyrimethamine (SP), which is the current national treatment ...
  https://clinicaltrials.gov/ct2/show/NCT00140361
*  A Phase I Study of Pyrimethamine in Patients With GM2 Gangliosidosis - Full Text View - ClinicalTrials.gov
In 2006 ExSAR applied for orphan drug designation from the FDA for Pyrimethamine (Pyrimethamine) for the treatment of patients ... Drug: Pyrimethamine Pyrimethamine will be given PO once daily for 8 consecutive weeks. ... Pyrimethamine at 6.25, 12.5, 25 and 37.5 mg/day will be evaluated sequentially, starting from 6.25 mg/day. Escalation from 6.25 ... Pyrimethamine is an FDA-approved drug which readily passes the bloodbrain barrier (BBB). It is currently used to treat malaria ...
  https://clinicaltrials.gov/ct2/show/NCT00679744?cond=%22Sandhoff+disease%22&rank=2
*  A Phase I Study of Pyrimethamine in Patients With GM2 Gangliosidosis - Full Text View - ClinicalTrials.gov
In 2006 ExSAR applied for orphan drug designation from the FDA for Pyrimethamine (Pyrimethamine) for the treatment of patients ... Drug: Pyrimethamine Pyrimethamine will be given PO once daily for 8 consecutive weeks. ... A Phase I Study of Pyrimethamine in Patients With GM2 Gangliosidosis. The safety and scientific validity of this study is the ... Pyrimethamine is an FDA-approved drug which readily passes the bloodbrain barrier (BBB). It is currently used to treat malaria ...
  https://clinicaltrials.gov/ct2/show/NCT00679744?term=Tay-Sachs+Disease&rank=2