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*  Drosophila melanogaster - Wikipedia
About 75% of known human disease genes have a recognizable match in the genome of fruit flies, and 50% of fly protein sequences ... It has only four pairs of chromosomes: three autosomes, and one pair of sex chromosomes. Males do not show meiotic ... Three major genes are involved in determination of Drosophila sex. These are sex-lethal, sisterless, and deadpan. Deadpan is an ... At metamorphosis, the larva forms a pupa, inside which the larval tissues are reabsorbed and the imaginal tissues undergo ...
  https://en.wikipedia.org/wiki/Drosophila_melanogaster
*  Drosophila melanogaster : Wikis (The Full Wiki)
About 75% of known human disease genes have a recognizable match in the genetic code of fruit flies,[19] and 50% of fly protein ... D. melanogaster chromosomes to scale with megabase-pair references oriented as in the National Center for Biotechnology ... More than 60% of the genome appears to be functional non-protein-coding DNA[17] involved in gene expression control. ... At metamorphosis, the larva forms a pupa, inside which the larval tissues are reabsorbed and the imaginal tissues undergo ...
  http://www.thefullwiki.org/Drosophila_melanogaster
*  Protocols and Video Articles Authored by Lance Parsons (Translated to Korean)
The tiny macronuclear "nanochromosomes" typically encode single, protein-coding genes (a small portion, 10%, encode 2-8 genes ... suggests several candidate proteins that could be involved in genome rearrangement, including domesticated MULE and IS1595-like ... We also positioned sequences mapped to the second and X chromosomes to finer intervals by analyzing smaller deletions with ... Interestingly, 5% of the single base pair substitutions might represent double-slippage events that occurred at the junction of ...
  https://www.jove.com/author/Lance_Parsons?language=Korean
*  Schistosoma mansoni - Wikipedia
... of the bases organised into chromosomes. Schistosome eggs, which may become lodged within the hosts tissues, are the major ... When they recognise human skin, they penetrate it within a very short time. This occurs in three stages, an initial attachment ... It involves methylene blue-stained cellophane soaked in glycerine or glass slides. A bit costlier technique called formalin- ... "Killer parasites' genes decoded". BBC News. July 16, 2009. Retrieved 2009-07-16. Anna V. Protasio; Isheng J. Tsai; Anne Babbage ...
  https://en.wikipedia.org/wiki/Schistosoma_mansoni
*  Chimpanzee genome project - Wikipedia
Several genes involved in hearing were also found to have changed during human evolution, suggesting selection involving human ... Human and chimpanzee chromosomes are very similar. The primary difference is that humans have one fewer pair of chromosomes ... Many ribosomal protein L23a pseudogenes are scattered through the human genome. Human evolutionary genetics Human chromosome 2 ... which is important for ion transport in tissues such as the salt-secreting epithelium of sweat glands. Human mutations in the ...
  https://en.wikipedia.org/wiki/Chimpanzee_genome_project
*  Hemoglobinopathies facts, information, pictures | Encyclopedia.com articles about Hemoglobinopathies
Genes code for proteins. Because of that change in one nucleotide, a slightly different protein is produced. HbS differs from ... Since individuals possess a total of four genes for the alpha polypeptide (two genes on each of their two chromosomes 16), ... Like HbA, fetal hemoglobin contains a pair of alpha chains. But in place of the beta chains, it contains a pair of gamma chains ... When the concentration of oxygen is low, as it is deep in the body's tissues, HbS molecules will attach to each other. Since a ...
  https://www.encyclopedia.com/medicine/diseases-and-conditions/pathology/hemoglobinopathies
*  Cell (biology) - WOW.com
Although the mitochondrial DNA is very small compared to nuclear chromosomes,[3] it codes for 13 proteins involved in ... Protein synthesis. An overview of protein synthesis.. Within the nucleus of the cell (light blue), genes (DNA, dark blue) are ... including 22 homologous chromosome pairs and a pair of sex chromosomes. The mitochondrial genome is a circular DNA molecule ... A human cell has genetic material contained in the cell nucleus (the nuclear genome) and in the mitochondria (the mitochondrial ...
  http://www.wow.com/wiki/Cell_
*  Metabolism, Genomics, and DNA Repair in the Mouse Aging Liver
U. Rass, S. A. Compton, J. Matos et al., "Mechanism of Holliday junction resolution by the human GEN1 protein," Genes and ... Some proteins involved NER may, in some cases, also participate in the repair for certain oxidative lesions, mostly via protein ... many proteins of the NHEJ reaction are required for the maintenance of the telomeric ends of chromosomes, including Ku70, Ku80 ... or LacZ reporter genes have been intensively used to estimate the mutation frequency or rate in the genome of different tissues ...
  https://www.hindawi.com/journals/cggr/2011/859415/
*  Wireless Harm
... these emissions are received by the chromosomes and the probability is increased that the promoter regions of the genes ... Human brain tissue is maximally resonant in the Ultra High Frequency (UHF) bands between around 800 MHz-3 GHz -- right where ... Instead, the microwave pulse, upon absorption by soft tissues in the head, launches a thermoelastic wave of acoustic pressure ... regions of the cell membranes separated by embedded proteins, these proteins themselves and other cytoplasmic biomolecules. ...
  http://www.freewebs.com/maggiezhou/wirelessharm.htm
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
The end result is a metaphase and a karyotype classification image, in which each pair of chromosomes has a distinct color ( ... Chromosomes can be isolated from cells of live tissues, including blood lymphocytes, skin fibroblasts, amniocytes, placenta, ... for aberrations that involve gains or losses of portions of the genome and rearrangements involving one or more chromosomes. In ... Isolating highly pure human lymphatic endothelial cells (LECs) from diseased and healthy tissue would facilitate studies of the ...
  https://www.jove.com/visualize/abstract/25923652/fetal-calcifications-are-associated-with-chromosomal-abnormalities
*  MTRR (gene) - Wikipedia
"Polymorphisms in genes involved in folate metabolism as maternal risk factors for Down syndrome". American Journal of Human ... Binding domain involved in the interaction with proteins or protein complexes. (MTRR):c.66A>G - Polymorphism resulting in ... MTRR):r.1462_1557del96 - Associated with splicing of exon 11 due to a 7 base pair deletion. A large deletion of this mutant ... Mainly three different halotypes (GTACG, GCACA, GCACG) from the deamination of methyl cytosine in different chromosomes. (MTRR ...
  https://en.wikipedia.org/wiki/MTRR_(gene)
*  Patent US7507873 - Transgenic avians containing recombinant ovomucoid promoters - Google Patents
Pairs of genes control hereditary traits, each in the same position on a pair of chromosomes. These gene pairs, or alleles, may ... Proteins such as growth hormones, cytokines, structural proteins and enzymes, including human growth hormone, interferon, ... These methods involve a variety of techniques, such as treating the cells with high concentrations of salt such as, but not ... The term "tissue-specific chimeric animal" indicates that the recombinant gene is present and/or expressed in some tissues but ...
  http://www.google.com/patents/US7507873?dq=5920316
*  Chromosome conformation capture - Wikipedia
For example, in tissues that express globin genes, the β-globin locus control region forms a loop with these genes. This loop ... The pair of sequences are individually aligned to the genome, thus determining the fragments involved in that ligation event. ... In 2003, the Human Genome Project was finished. In 2006, Marieke Simonis invented 4C , Dostie invented 5C . In 2007, B. ... ChIP-loop combines 3C with ChIP-seq to detect interactions between two loci of interest mediated by a protein of interest. The ...
  https://en.wikipedia.org/wiki/Chromosome_conformation_capture
*  ATP-binding cassette transporter - Wikipedia
Human ABC transporters are involved in several diseases that arise from polymorphisms in ABC genes and rarely due to complete ... One class is involved in the protein (e.g. toxins, hydrolytic enzymes, S-layer proteins, lantibiotics, bacteriocins, and ... All of subgroup 2 is organized into a head to tail cluster of chromosomes on chromosome 17q24. Genes in this second subgroup ... Each member of the ABCF subgroup consist of a pair of ATP binding domains. Six half transporters with ATP binding sites on the ...
  https://en.wikipedia.org/wiki/ATP-binding_cassette_transporter
*  A Human Protein Atlas for Normal and Cancer Tissues Based on Antibody Proteomics | Molecular & Cellular Proteomics
Altogether 718 antibodies representing all human chromosomes were used to create the protein atlas, although the focus was on ... 4a). This gene product contains a type 1 RING-type zinc finger, and the protein is reported to be involved in cell cycle ... Number of genes/antibodies included in the database. The graph shows the number of genes per chromosome included in the ... Each pair (a and b and c and d) corresponds to antibodies generated against the same antigen in two different animals. The red ...
  http://www.mcponline.org/content/4/12/1920
*  Genetic Basis Of Life
... histone proteins organize the chromosome. 6. The spindle is involved in distributing the daughter chromosomes to the daughter ... 3. Therapeutic cloning to produce human tissues can begin with either adult stem cells or embryonic stem cells. 4. Embryonic ... b. The chromosomes have mutated; some chromosomes may be duplicated or deleted. c. Gene amplification, extra copies of genes, ... 2. Each centrosome contains a pair of barrel-shaped organelles called centrioles. 3. The mitotic spindle contains many fibers, ...
  https://www.slideshare.net/mandalina/genetic-basis-of-life
*  Genome-wide matching of genes to cellular roles using guilt-by-association models derived from single sample analysis | BMC...
... methods that ascribe a cellular or physiological function for each gene product are useful to understand the roles of genes ... PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet. ... Olfactory receptors are G-protein coupled receptors expressed in the main olfactory epithelia and other tissues that bind small ... Not all genes described in the book Genome were examined nor were all of the chromosomes represented. 5SRNA genes were ...
  https://bmcresnotes.biomedcentral.com/articles/10.1186/1756-0500-5-370
*  Thalassemia | Encyclopedia.com
... the oxygen-carrying protein inside the red blood cells. There are two basic groups of thalassemia disorders: alpha thalassemia ... HLA type- Refers to the unique set of proteins called human leukocyte antigens. These proteins are present on each individual's ... Globin- One of the component protein molecules found in hemoglobin. Normal adult hemoglobin has a pair each of alpha-globin and ... Red blood cell- Hemoglobin-containing blood cells that transport oxygen from the lungs to tissues. In the tissues, the red ...
  https://www.encyclopedia.com/medicine/diseases-and-conditions/pathology/thalassemia
*  Proteome of the human heart mapped for the first time
... thanks to the interplay of more than 10,000 proteins. Researchers from the Max Planck Institute of Biochemistry (MPIB) and the ... Each cell in the average human body contains 23 pairs of chromosomes, with four telomeres on each pair. Telomeres cover the end ... The comparison provided yet another interesting finding: Although the proteins involved in energy metabolism were changed in ... Id genes play surprise role in cardiac development. August 22, 2017 Researchers from Sanford Burnham Prebys Medical Discovery ...
  https://medicalxpress.com/news/2017-11-proteome-human-heart.html
*  Promoter Hypermethylation of the EMP3 Gene in a Series of 229 Human Gliomas
T. Liehr, G. Kuhlenbäumer, P. Wulf et al., "Regional localization of the human epithelial membrane protein genes 1, 2, and 3 ( ... Protein Extraction and Western Blotting (WB). Whole protein extracts from cells and FFPE tissues were isolated using a lysis ... The 144-base pair peak refers to the methylated allele (M) and the 155-base pair peak to the unmethylated allele (U). Arrow ... 1p and 19q chromosomes were considered to be completely deleted if all consecutive probes on 1p or 19q showed a ratio ,0.75. In ...
  https://www.hindawi.com/journals/bmri/2013/756302/
*  Frontiers | Identifying putative breast cancer-associated long intergenic non-coding RNA loci by high density SNP array...
Interestingly, lincRNA genes appear to be much less susceptible to CNV in comparison to both protein-coding and intergenic ... 700 nt throughout the intergenic region of the human genome. We mapped annotated or putative lincRNA genes to a subset of ... aberrations were detected predominantly with copy number losses and preferential clustering to the ends of chromosomes. ... Interestingly, lincRNA genes appear to be much less susceptible to CNV in comparison to both protein-coding and intergenic ...
  https://www.frontiersin.org/articles/10.3389/fgene.2012.00299/full
*  Most recent papers with the keyword Chia-pet | Read by QxMD
We examined human neutrophils and CD4 primary T cells to identify genes and functional elements located within those risk loci ... It is becoming clear that structural-maintenance-of-chromosomes (SMC) complexes such as condensin and cohesin are involved in ... Results: We developed a web browser, HUGIn, to visualize Hi-C data generated from 21 human primary tissues and cell lines. ... HiChIP: efficient and sensitive analysis of protein-directed genome architecture.. Maxwell R Mumbach, Adam J Rubin, Ryan A ...
  https://www.readbyqxmd.com/keyword/21782
*  Frontiers | Integrated Analysis of DNA Methylation and mRNA Expression Profiles to Identify Key Genes in Severe Oligozoospermia...
Integrated pathways analysis indicates that these genes are involved in response to hormone stimulus, activation of protein ... In this study, we examined DNA methylation and mRNA expression status in a set of testicular tissues of SO patients (n=3), and ... Integrated pathways analysis indicates that these genes are involved in response to hormone stimulus, activation of protein ... We also observed some genes with inversely correlated difference is novel in male infertility field, including PTPRN2, EPHX1, ...
  https://www.frontiersin.org/articles/10.3389/fphys.2017.00261/full
*  Gene Report for G00001955 - Genes2Cognition Neuroscience Research Programme
Sites of transcription of polyadenylated and nonpolyadenylated RNAs for 10 human chromosomes were mapped at 5-base pair ... A SNARE involved in protein transport through the Golgi apparatus.. Lowe SL, Peter F, Subramaniam VN, Wong SH and Hong W ... Human clathrin. Human orthologues of mouse clathrin coated vesicle genes adapted from Collins et al (2006). 150. ... Two of these proteins, alpha and gamma, are found in a wide range of tissues, and act synergistically in intra-Golgi transport ...
  http://www.genes2cognition.org/db/Gene/G00001955
*  Detection of a common chimeric transcript between human chromosomes 7 and 16 | Biology Direct | Full Text
... especially those involving genes on separate chromosomes, in normal human cells. We mined high-throughput RNA-seq data from ... a protein, and 2. an RNA that might serve to proximally position chromosomes. While the transcript has some of the hallmarks of ... we first verified the presence of this chimeric transcript in human mammary cells. Use of a primer pair (Table 1) that ... CHMP1A chimeric RNA in human cells and tissues. Filled arrowhead indicates the major predicted fusion; open arrowheads indicate ...
  https://0-biologydirect-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/1745-6150-7-49