Identification of a novel temperature sensitive promoter in cho cells | BMC Biotechnology | Full Text
3. Promoter mapping and dissection. The 1.5 kb upstream region of the CHO S100a6 gene was examined for promoter activity using ... In this context, the genetic vector construct has to be considered since it significantly affects productivity . For ... these strong promoters can also trigger the undesired silencing phenomenon due to methylation of the promoter region and part ... Beside TATA-box promoters, the majority of mammalian promoters occur as so called CpG island promoters  where the ...https://bmcbiotechnol.biomedcentral.com/articles/10.1186/1472-6750-11-51
Progesterone Receptor Isoform-Specific Promoter Methylation: Association of PRA Promoter Methylation with Worse Outcome in...
... the presence of DNA methylation at each promoter region could be potentially used as a surrogate marker for PR isoform status. ... A sensitive genetic assay for the detection of cytosine deamination: determination of rate constants and the activation energy ... In our study, PRA promoter was methylated in 9.5% of breast tumors and PRB promoter was methylated in 14.1% breast tumors, ... Progesterone Receptor Isoform-Specific Promoter Methylation: Association of PRA Promoter Methylation with Worse Outcome in ...http://clincancerres.aacrjournals.org/content/17/12/4177.long
Patent US7074590 - Chimeric promoters - Google Patents
The chimeric promoter/enhancers are particularly suitable for directing gene expression in mammalian cells. ... For example, the major IE region promoter/enhancer regions of the resulting library of chimeric promoter nucleic acids was ... Therefore, promoters of the invention having a range of activities are likely to be useful in the dose escalation of genetic ... A promoter is sometimes bounded at its 3′ terminus by the transcription initiation site, but often the promoter/enhancer region ...http://www.google.co.uk/patents/US7074590
We produced Tg mice that carry the IL-2Rα/GFP gene cassette downstream of the 5′-flanking region of the gene encoding NP, which ... under the control of a cell type-specific promoter. These mice are then treated with a recombinant immunotoxin (IT), which is ... Genetic alteration of catecholamine specificity. Proc Natl Acad Sci USA 89: 1631-1635. ... The transgene construct contained a 10 kb DNA fragment encoding the 5′-flanking region of the mouse neuropsin (NP) gene (Hirata ...http://www.jneurosci.org/content/25/34/7743
Promoter Regions, Genetic | Colorado PROFILES
"Promoter Regions, Genetic" by people in this website by year, and whether "Promoter Regions, Genetic" was a major or minor ... "Promoter Regions, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical ... Promoter Regions, Genetic*Promoter Regions, Genetic. *Genetic Promoter Region. *Genetic Promoter Regions ... Below are the most recent publications written about "Promoter Regions, Genetic" by people in Profiles. ...https://profiles.ucdenver.edu/display/219535
Association of Genetic Variation in the Promoter Region of OXTR with Differences in Social Affective Neural Processing
... we investigated the effect of variation in the common functional rs2268498 T/C polymorphism in the promoter region of OXTR on ... These results indicate the impact of this OXTR genetic variant on individual differences in social affective neural processing. ... "Association of Genetic Variation in the Promoter Region of OXTR with Differences in Social Affective Neural Processing," ... we investigated the effect of variation in the common functional rs2268498 T/C polymorphism in the promoter region of OXTR on ...http://www.scirp.org/journal/PaperInformation.aspx?paperID=17727
Genetic polymorphisms in promoter and intronic regions of CYP1A2 gene in Roma and Hungarian population samples. - PubMed - NCBI
Genetic polymorphisms in promoter and intronic regions of CYP1A2 gene in Roma and Hungarian population samples.. Szalai R1, ...https://www.ncbi.nlm.nih.gov/pubmed/25461540
Association of Genetic Variation in the Promoter Region of OXTR with Differences in Social Affective Neural Processing
... and genetic variation in OXTR  on emotion processing in the amygdala and connected social brain regions . ... we investigated the effect of variation in the common functional rs2268498 T/C polymorphism in the promoter region of OXTR on ... parietal cortex and occipital regions (Pcorr < 0.01). For fear versus neutral activated regions were restricted to the right ... Effect of OXTR genetic variation at SNP rs- 2268498 during the emotion processing task. The T/T group (n = 14) had bilaterally ...http://file.scirp.org/Html/7-3900070_17727.htm
Association of genetic variants in the promoter region of genes encoding p22phox (CYBA) and glutamate cysteine ligase catalytic...
Association of genetic variants in the promoter region of genes encoding p22phox (CYBA) and glutamate cysteine ligase catalytic ... at the promoter region of the CYBA and GCLC genes modulate the risk for decreased GFR in type 1 diabetes patients even after ... in the promoter region of three genes related to cellular redox balance: (1) -675 T → A in CYBA (unregistered), where the T ... Biochemical and genetic characterization of Italian subpopulation. Am Heart J. 2007, 154: 1123-1129. 10.1016/j.ahj.2007.07.029. ...https://0-bmcmedgenet-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/1471-2350-12-129
WUSCHEL is a primary target for t... preview & related info | Mendeley
... important role in ensuring proper development in higher eukaryotes by controlling accessibility of cis-regulatory DNA regions ... Promoter Regions, Genetic/genetics. *Reverse Transcriptase Polymerase Chain Reaction. *Sequence Analysis, DNA ... Using genetic and molecular analyses we have identified WUSCHEL (WUS) as a biologically important target of the SNF2-class ... We present evidence that SYD is recruited to the WUS promoter and that it is involved in regulation of the stem cell pool ...https://www.mendeley.com/research-papers/wuschel-primary-target-transcriptional-regulation-splayed-dynamic-control-stem-cell-fate-arabidopsis/
Masculine epigenetic sex marks of the CYP19A1/aromatase promoter in genetically male chicken embryonic gonads are resistant to...
... the genetic sex is experimentally reversible by in ovo exposure to exo ... Genetic Markers. Male. Ovary / drug effects, embryology. Phenotype. Promoter Regions, Genetic. RNA, Messenger / genetics, ... In this study, we show that a 170-nt region in the promoter of CYP19A1/aromatase, a key gene required for ovarian estrogen ... Epigenesis, Genetic / drug effects. Ethinyl Estradiol / administration & dosage. Female. Feminization / chemically induced, ...http://www.biomedsearch.com/nih/Masculine-Epigenetic-Sex-Marks-Promoter/22539680.html
A polymorphism in the serotonin transporter gene moderates cardiovascular reactivity to psychosocial stress.
... in the promoter of the serotonin transporter gene (SLC6A4) moderates cardiovascular reactivity to social threat. ... Polymorphism, Genetic / genetics. Promoter Regions, Genetic. Psychological Tests. Serotonin / genetics*, physiology. Serotonin ... OBJECTIVE: To examine whether a polymorphism (5-HTTLPR: serotonin transporter linked polymorphic region) in the promoter of the ...http://www.biomedsearch.com/nih/Polymorphism-in-Serotonin-Transporter-Gene/21364196.html
Transcription of the extended hyp-operon in Nostoc sp. strain PCC 7120.
Promoter Regions, Genetic. Tandem Repeat Sequences. Transcription Initiation Site. Transcription, Genetic*. Chemical. ... The promoter region upstream hypF contains an extended -10 box (TGNTAN3T) which belongs to a subclass of E. coli promoters ... Schematic presentation of the regulatory promoter regions of (A) asr0689, (B) hypF and (C) hypC. Putative NtcA, -35, -10, ... strain PCC 7120, is transcribed together with the hyp-genes with a defined TSP and a promoter region putatively controlled by ...http://www.biomedsearch.com/nih/Transcription-extended-hyp-operon-in/18442387.html
beta-Catenin is not necessary for maintenance or repair of the bronchiolar epithelium.
Promoter Regions, Genetic. RNA, Messenger / metabolism. Rats. Regeneration* / drug effects, genetics. Respiratory Mucosa / drug ... Repair of the naphthalene-injured airway proceeded with establishment of focal regions of beta-catenin-null epithelium. The ...http://www.biomedsearch.com/nih/beta-Catenin-Not-Necessary-Maintenance/19213872.html
The -1185 A/G and -1051 G/A dimorphisms in the von Willebrand factor gene promoter and risk of myocardial infarction.
Recently, four linked dimorphisms in the VWF gene promoter were demonstrated to influence plasma VWF l ... Polymorphism, Genetic*. Promoter Regions, Genetic*. Risk. Smoking / adverse effects. von Willebrand Factor / genetics*. ... Recently, four linked dimorphisms in the VWF gene promoter were demonstrated to influence plasma VWF level. We conducted a case ...http://www.biomedsearch.com/nih/1185-1051-dimorphisms-in-von/11736957.html
Site-specific chromatin immunoprecipitation: a selective method to individually analyze neighboring transcription factor...
Promoter Regions, Genetic. Protein Binding. Receptor, Epidermal Growth Factor / chemistry, genetics, metabolism*. Sp1 ... Site-specific ChIP on cell culture extracts: Individual detection of Sp1 TFBSs within the egfr promoter region. PCR-based ... In the center of the image, the egfr promoter region with all investigated Sp1 TFBSs and enzyme cleavage sites is shown. Dashed ... Sp1 TFBSs within egfr promoter region are represented by grey oval disks, indicating their positions in relation to the ...http://www.biomedsearch.com/nih/Site-specific-chromatin-immunoprecipitation-selective/22348285.html
Pluripotential reprogramming of the somatic genome in hybrid cells occurs with the first cell cycle.
Oct4-green fluorescent protein (GFP) transgenes that do not contain the proximal enhancer (PE) region are widely used to ... Promoter Regions, Genetic. Recombinant Fusion Proteins / genetics. Chemical. Reg. No./Substance: 0/Octamer Transcription Factor ... Enhancer Elements, Genetic. Female. Gene Expression Regulation. Genome. Green Fluorescent Proteins / genetics. Hybrid Cells / ... In the current study, we show that activation of an Oct4-GFP transgene that contains the PE region occurs within 22 hours of ...http://www.biomedsearch.com/nih/Pluripotential-reprogramming-somatic-genome-in/18065396.html
Histone deacetylation during brain development is essential for permanent masculinization of sexual behavior.
Promoter Regions, Genetic. Rats. Rats, Sprague-Dawley. Sex Characteristics. Sex Differentiation*. Sexual Behavior, Animal* / ... Consistent with these findings, binding of histone deacetylase (HDAC) 2 and 4 to the promoters was higher in males than in ... It was found that during the critical period for sexual differentiation, histones associated with promoters of essential genes ...http://www.biomedsearch.com/nih/Histone-Deacetylation-during-Brain-Development/21586557.html
Growth hormone signal transduction.
Promoter Regions, Genetic / genetics. Protein-Tyrosine Kinases / physiology. Proto-Oncogene Proteins*. Receptor, Insulin / ...http://www.biomedsearch.com/nih/Growth-hormone-signal-transduction/12099386.html
Impact of sodium/proton exchanger 3 gene variants on sudden infant death syndrome.
Variations in the exons and promoter of the NHE3 gene were analyzed with direct sequencing analy ... Genetic Variation*. Humans. Infant. Male. Medulla Oblongata. Molecular Sequence Data. Promoter Regions, Genetic / genetics. ... CONCLUSIONS: Our findings suggest the involvement of polymorphisms in the NHE3 gene and promoter in cases of SIDS, which may ... RESULTS: The C2405T variant (exon 16) and 2 polymorphisms in the promoter (G1131A and C1197T) were encountered significantly ...http://www.biomedsearch.com/nih/Impact-Exchanger-3-Gene-Variants/19772970.html
In vivo expression profile of an endothelial nitric oxide synthase promoter-reporter transgene.
Promoter Regions, Genetic / genetics*. RNA, Messenger / analysis. Renal Circulation / physiology. Transgenes / genetics*. ... promoter-reporter insertional transgenic murine lines were created containing 5,200 bp of the native murine eNOS promoter ... These transgenic eNOS promoter-reporter lines will be a valuable resource for ongoing studies addressing the regulated ... Only in the brain was the reporter expressed in non-endothelial cell types, such as the CA1 region of the hippocampus. ...http://www.biomedsearch.com/nih/In-vivo-expression-profile-endothelial/10749733.html
Association of LIPC and advanced age-related macular degeneration.
Promoter Regions, Genetic / genetics. Chemical. Reg. No./Substance: EC 126.96.36.199/LIPH protein, human; EC 188.8.131.52/Lipase ... in the promoter region of LIPC. The associations between the SNPs and AMD were examined by χ(2) tests.. RESULTS: In the ... Genetic Predisposition to Disease. Humans. Lipase / genetics*. Macular Degeneration / genetics*. Male. Middle Aged. ... CONCLUSION: The LIPC promoter variants rs493258 and rs10468017 were associated with advanced AMD in two independent Caucasian ...http://www.biomedsearch.com/nih/Association-LIPC-advanced-age-related/23348725.html
LH-induced neuregulin 1 (NRG1) type III transcripts control granulosa cell differentiation and oocyte maturation.
Promoter Regions, Genetic / genetics. Proto-Oncogene Proteins c-akt / metabolism. RNA, Messenger / genetics, metabolism. ...http://www.biomedsearch.com/nih/LH-Induced-Neuregulin-1-NRG1/21047912.html
Insights into the genetic foundation of aggression in Papio and the evolution of two length-polymorphisms in the promoter...
... into the genetic foundation of aggression in Papio and the evolution of two length-polymorphisms in the promoter regions of ... Insights into the genetic foundation of aggression in Papio and the evolution of two length-polymorphisms in the promoter ... Insights into the genetic foundation of aggression in Papio and the evolution of two length-polymorphisms in the promoter ... into the genetic foundation of aggression in Papio and the evolution of two length-polymorphisms in the promoter regions of ...https://kops.uni-konstanz.de/handle/123456789/40026
Endothelial-specific CYP4A2 overexpression leads to renal injury and hypertension via increased production of 20-HETE. |...
Promoter Regions, Genetic. *Proteinuria (metabolism) *Proto-Oncogene Proteins c-akt (metabolism) *Rats ... vascular endothelium by using a lentivirus construct expressing CYP4A2 under the control of the endothelium-specific promoter ...http://www.curehunter.com/public/pubmed19675180.do