Development of dengue virus replicons expressing HIV-1 gp120 and other heterologous genes: a potential future tool for dual...
We cloned into a Δpre-M/E dengue virus replicon genes for either green fluorescent protein (GFP), HIV gp160 or HIV gp120 and ... This suggested that gp160 expressed from dengue virus replicons is considerably more toxic than either GFP or gp120. The ... Previously we reported the successful construction of dengue virus replicons which lack structural genes necessary for virion ... we have attempted to create vectors which express dengue virus non-structural proteins and HIV immunogens. ...https://bmcmicrobiol.biomedcentral.com/articles/10.1186/1471-2180-1-28
Multiple nuclear-replicating viruses require the stress-induced protein ZC3H11A for efficient growth | PNAS
... herpes simplex virus, and adenovirus), whereas cytoplasmic replicating viruses are not (vaccinia virus and Semliki Forest virus ... by several nuclear-replicating viruses to promote their replication. ZC3H11A is therefore a potential target for development of ... and two viruses with a cytoplasmic replication cycle [vaccinia virus Western Reserve strain (VV) and Semliki Forest virus (SFV ... herpes simplex virus ICP27 and herpes virus saimiri ORF57 (32), Epstein-Barr virus EB2 (33), and human cytomegalovirus UL69 (34 ...http://www.pnas.org/content/115/16/E3808
Vaccine Media | BioFiles Volume 5 Number 3 Vaccine Adjuvants | Sigma-Aldrich
Avian oncolytic viruses (NDV / IBDV...). Newcastle disease virus. Bovine parainfluenza virus. Smallpox virus (Lister, Vaccinia ... Sindbis virus. Infectious bronchitis virus. Semliki forest virus. Encephalomyelitis virus. Venezuelan EEV virus. Anemia virus ( ... More recently, the potential for contamination by adventitious agents present in serum has heightened regulatory concerns ... Influenza virus. Influenza virus. Influenza virus (swine, equine). Canine distemper virus. Measles virus. Reovirus. Eastern ...http://www.sigmaaldrich.com/life-science/learning-center/biofiles/biofiles-5-3/vaccine-media.html
WO2002081709 GENES ET PROTEINES E6 ET E7 DU PVH MODIFIES POUVANT SERVIR A LA VACCINATION
Suitable viruses that may be used in the present invention include baculovirus, vaccinia, sindbis virus, SV40, Sendai virus, ... herpes simplex virus type 1 amplicon or recombinant Semliki forest virus vectors . Said DNA sequences encode the HPV proteins ... The transforming potential of the enhanced genes of the present invention and of their derivatives (fusion proteins like that ... 2) E2 glycoprotein of Semliki forest virus (SFV) . E2 is a spike component of the SFV virion and a major antigen for ...https://patentscope.wipo.int/search/fr/detail.jsf
Elucidation of antigenic epitopes on the rubella virus E1 glycoprotein - UBC Library Open Collections
Semliki Forest virus, Sindbis virus and Rubella virus. J. Gen. Virol 46:467-475.Vaheri, A. and Hovi, T. (1972) Structural ... Vaccinia recombinantsCV-1 cells were infected with vaccinia virus recombinants (E1, E2 and C, preparedin this laboratory) at 5 ... The potential . use of the defined epitopes in the developmentof subunit vaccine is discussed.TABLE OF CONTENTSABSTRACTTABLE OF ... Complexing of viruses withIgG antibody will also facilitate their phagocytosis by macrophages via Fc receptors onthese cells. ...https://open.library.ubc.ca/cIRcle/collections/ubctheses/831/items/1.0098839
NONNEUROTROPIC ADENOVIRUS: A VECTOR FOR GENE TRANSFER TO THE BRAIN AND GENE THERAPY OF NEUROLOGICAL DISORDERS
Semliki Forest virus (SFV), vaccinia], or promoter shut-off, a poorly understood phenomenon by which promoters within viral ... The potential for efficacy of the modified (ICP 34.5(−)) herpes simplex virus HSV1716 following intratumoural injection into ... Immune responses to viruses: Practical implications for the use of viruses as vectors for experimental and clinical gene ... Helper virus-free herpes simplex virus type 1 amplicon vectors for granulocyte-macrophage colony-stimulating factor-enhanced ...http://pubmedcentralcanada.ca/pmcc/articles/PMC2902245/
HIV Vaccine: Recent Advances, Current Roadblocks, and Future Directions
Measles virus (MV), modified vaccinia virus Ankara (MVA), vesicular stomatitis virus (VSV), canarypox (ALVAC), Semliki forest ... The potential candidates selected were ALVAC-C (expressing ZM96 gp120 (clade C strain) linked to gp41, and gag and pro clade B ... The majority of the neutralizing antibodies are directed towards the Env, which the viruses keep mutating to evade the host ... Venezuelan equine encephalitis virus (VEE), Sindbis virus (SIN), herpes simplex virus (HSV), ...https://www.hindawi.com/journals/jir/2015/560347/
Oncolytic virus - Wikipedia
Semliki Forest virus (SFV) is a virus that naturally infects cells of the central nervous system and causes encephalitis. A ... A number of viruses including adenovirus, reovirus, measles, herpes simplex, Newcastle disease virus and vaccinia have now been ... The potential of viruses as anti-cancer agents was first realised in the early twentieth century, although coordinated research ... JX-594 is a thymidine kinase-deleted Vaccinia virus plus GM-CSF. Seneca Valley virus (NTX-010) and (SVV-001), oncolytic ...https://en.wikipedia.org/wiki/Oncolytic_virus
Booktopia - New Comprehensive Biochemistry - Vol 38, Volume 38 by Makrides, 9780444513717. Buy this book online.
Virus-based vectors for gene expression in mammalian cells: Semliki Forest virus. p. 207. ... Virus-based vectors for gene expression in mammalian cells: Vaccinia virus. p. 125. ... Co-transfer of multiple plasmids/viruses as an attractive method to introduce several genes in mammalian cells. p. 337. ... Poliovirus vector development and its immunogenic potential. p. 176. Abbreviations. p. 185. ...https://www.booktopia.com.au/new-comprehensive-biochemistry-vol-38-makrides/prod9780444513717.html
Patent US20030052839 - Stabilized viral envelope proteins and uses thereof - Google Patents
... polyoma virus, adenovirus, vaccinia virus, baculovirus, retroviruses (RSV, MMTV or MOMLV), Semliki Forest virus or SV40 virus. ... Alternatively, viruses with heightened stability could in principle be selected following successive exposure of virus to ... It also means decreasing the potential of the subject to transmit the virus to an uninfected subject. ... the virus is the simian immunodeficiency virus. Another embodiment of the above virus is the human immunodeficiency virus (HIV ...http://www.google.com/patents/US20030052839
Assessment of the in vitro broad-spectrum antiviral activity of some selected antitumor organotin complexes.
... and vaccinia virus. The RNA viruses were vesicular stomatitis virus, Coxsackie virus type B4, Sindbis virus, Semliki forest ... this group of antitumor organotin complexes yields little promise as potential antiviral drugs. 9. Larnicol, N, Augery, Y, ... and vaccinia virus. The RNA viruses included vesicular stomatitis virus, Coxsackie virus type B4, Sindbis virus, Semliki forest ... vaccinia virus, vesicular stomatitis virus, Coxsackie virus type B4, and Sindbis virus - (see Ref. 16); Semliki forest virus ( ...https://www.docme.ru/doc/1902679/assessment-of-the-in-vitro-broad-spectrum-antiviral-activ..
Viruses: LECTURE TOPICS - PDF
LECTURE TOPICS Types of viruses: RNA and DNA Virus assembly: Simple (TMV) Complex (T4 bacteriophage) RNA viruses: Replication/ ... Infection Strategies (poliovirus) Membrane Viruses Influenza A SARS ... 20 Membrane viruses: Semliki Forest Virus (ss RNA). 21 Membrane virus infects cell by receptor-mediated endocytosis Cell and ... Vaccinia Virus. What is a Virus? Outline of Lecture. Result = horizontal gene transfer Fig. 13. Viruses and Prions Outline of ...http://docplayer.net/29349169-Viruses-lecture-topics.html
Patente US5441943 - Uses of aloe products - Google Patentes
... mayaro virus middleburg virus mucamba virus ndumu virus O'Nyong-nyong virus pixuna virus ross river virus semliki forest virus ... vaccinia virus smallpox virus cowpox virus monkeypox virus buffalopox virus camelpox virus ectromelia of mice virus rabbitpox ... Orf virus avipox virus sheep-pox virus goatpox virus lumpy skin disease (Neethling) virus myxoma virus of hares fibroma viruses ... The actual concentrations achievable in man have also bee shown to be in this range, further supporting the potential relevance ...http://www.google.es/patents/US5441943
CR-2 Binding Peptide P28 as Molecular Adjuvant for DNA Vaccines - Patent application
... which includes Sindbis virus, Semliki Forest virus (SFV) and Venezuelan equine encephalitis (VEE) virus. These RNA viruses ... recombinant vaccinia virus. Homologous boosting was weak or ineffective in this model (Sedegah M, 1998). `Self- ... 0047]The potential adjuvant effect of C3d in a DNA vaccine against P. berghei malaria was studied using a previously ... For this, some promoters derived from viruses such as cytomegalovirus (CMV) or simian virus 40 (SV40) have been used. A cloning ...http://www.patentsencyclopedia.com/app/20100255075
US Patent # 4,299,916. Preferential signal production on a surface in immunoassays - Patents.com
Equine Eucephalitis Virus Western Equine Eucephalitis Virus Sindbis Virus Chikugunya Virus Semliki Forest Virus Mayora Virus St ... Virus B Cytomegalovirus Pox Viruses Variola (smallpox) Vaccinia Poxvirus bovis Paravaccinia Molluscum contagiosum ... the potential for cross-linking of the linked compound, and the like. The linking group may be a bond or have up to about 12, ... Hepatitis A Virus Hepatitis B Virus Tumor Viruses Rauscher Leukemia Virus Gross Virus Maloney Leukemia Virus Epstein Barr Virus ...http://patents.com/us-4299916.html
DNA vaccination - Wikipedia
The Sindbis virus and Semliki Forest virus have been used to build recombinant alphavirus replicons. Unlike conventional DNA ... This was successfully demonstrated using recombinant vaccinia viruses expressing influenza proteins, but the principle should ... DNA vaccines have potential advantages over conventional vaccines, including the ability to induce a wider range of immune ... They altered the DNA of cowpox virus by inserting a gene from other viruses (namely Herpes simplex virus, hepatitis B and ...https://en.wikipedia.org/wiki/DNA_vaccination
METHODS OF TREATING ALZHEIMER'S DISEASE AND OTHER TAUOPATHIES WITH INHIBITORS OF MICROTUBULE AFFINITY REGULATING KINASE - THE...
Semliki Forest virus (SFV), and Venezuelan Equine Encephalitis virus (VEE), will also find use as viral vectors for delivering ... pox viruses and vaccinia viruses.. The term "derived from" is used herein to identify the original source of a molecule but is ... To circumvent potential functional redundancy among at least four mammalian MARK family members, we used a peptide inhibitor ( ... including vaccinia virus and avian poxvirus. By way of example, vaccinia virus recombinants expressing the CagA peptides or ...http://www.freepatentsonline.com/y2016/0030510.html
The Multiplicity of Cellular Infection Changes Depending on the Route of Cell Infection in a Plant Virus | Journal of Virology
Multiple mechanisms for the inhibition of entry and uncoating of superinfecting Semliki Forest virus. Virology 231:59-71. doi: ... Superinfection exclusion of vaccinia virus in virus-infected cell cultures. Virology 174:35-42. doi:10.1016/0042-6822(90)90051- ... in particular for other plant RNA viruses, such as Tobacco mosaic virus (TMV) (29), Soilborne wheat mosaic virus (SBWMV) (30), ... Potential differences in MOI depending on the route of infection, from the sieve elements versus from other cell types, ...https://jvi.asm.org/content/89/18/9665
HIV & AIDS Information :: Vaccines - Types of HIV vaccines
Semliki forest virus (SFV), and adeno-associated virus (AAV). All three have shown some success in animal studies. ... Researchers are working on the bird viruses fowlpox and canarypox, and bird-adapted strains of the smallpox virus vaccinia, ... Recombinant rabies virus as potential live-viral vaccines for HIV-1. Proc Natl Acad Sci U S A 97: 3544-3549, 2000 ... Vaccines can be made against toxins that bacteria and viruses produce as well as against parts of the mature virus. An example ...https://www.aidsmap.com/Types-of-HIV-vaccines/page/1065633/
Rabies and Related Lyssaviruses | SpringerLink
High-level expression of rabies virus glycoprotein with the RNA-based Semliki forest virus expression vector. J Biotechnol 139( ... Cross-protective and cross-reactive immune responses to recombinant vaccinia viruses expressing full-length lyssavirus ... Lee DN, Papeş M, Van den Bussche RA (2012) Present and potential future distribution of common vampire bats in the Americas and ... Lodmell DL, Esposito JJ, Ewalt LC (2004) Live vaccinia-rabies virus recombinants, but not an inactivated rabies virus cell ...https://link.springer.com/chapter/10.1007%2F978-3-319-90137-4_3
The interferon-induced double-stranded (ds)RNA-dependent protein kinase (PKR) limits viral replication by | Role of NK1 and NK2...
... rubella computer virus, Semliki Forest computer virus, Sindbis computer virus [43,44]), (SARS corona computer virus , ( ... Organic DNA viruses such as for example vaccinia pathogen, adenovirus, herpes virus or cytomegalovirus transcribe open up ... However, you can find obstructions that complicate the id of potential PKR activating RNAs within virus-infected cells. For ... Proof for these viral dsRNA originated from tests performing removal and re-annealing of RNA from computer virus contaminated ...http://stopvivisection.info/the-interferon-induced-double-stranded-dsrna-dependent-protein-kinase-pkr-limits-viral-replication-by/
SYNTHESIS AND ISOLATION OF DENDRIMER SYSTEMS - Patent application
... virus (German measles) and Semliki forest virus, arboviruses, and hepatitis type A virus.  It is contemplated that the ... and vaccinia virus; and RNA viruses, such as human immunodeficiency virus type I (HIV-I), human immunodeficiency virus type II ... Other techniques with potential to resolve product distributions such as gel permeation chromatography (GPC), high performance ... virus type II (HTLV-II), influenza virus, measles virus, rabies virus, Sendai virus, picornaviruses such as poliomyelitis virus ...http://www.patentsencyclopedia.com/app/20120232225
Indian Patents. 239166:A POLYNUCLEOTIDE HAVING THE NUCLEIC ACID SEQUENCE ACCORDING TO SEQ ID NO:1, 2 OR 3 OR A SEQUENCE FROM...
several other viruses are also qualified e.g. recombinant alpha-viruses, e.g. the Semliki-Forest. virus or the Venezuela- ... immunization with recombinant vaccine viruses such as Modified Vaccinia Ancara virus (MVA). attenuated by passage through ... Program (RIP, version 1.3; http://hiv-web.lanl.gov/tools) was used to identify potential mosaic. structures within the full- ... from alpha viruses such as Semliki-Forest (SFV) or Venezuela-Encephalitis virus (VEE). Here,. the aforementioned nuclear ...http://www.allindianpatents.com/patents/239166-a-polynucleotide-having-the-nucleic-acid-sequence-according-to-seq-id-no-1-2-or-3-or-a-sequence-from-the-nucleotide-numbers
MODIFIED LISTERIA BACTERIA AND USES THEREOF - Patent application
... such as Sindbis virus, Sindbis strain SAAR86, Semliki Forest virus (SFV), Venezuelan equine encephalitis (VEE), Eastern equine ... monkeypox virus, vaccinia virus, cowpox virus), yatapoxvirus (tanapox virus, Yaba monkey tumor virus), parapoxvirus, and ... AB195673; West Nile virus, AY762084). Dengue virus type 2 (see, e.g., GenBank Acc. Nos. Dengue viruses 1 to 4, NC--001474; ... For example, compounds that inhibit inosine monophosphate dehydrogenase (IMPDH) may have the potential to exert direct anti ...http://www.patentsencyclopedia.com/app/20150368654
Mutagenesis of the fusion peptide-like domain of hepatitis C virus E1 glycoprotein: involvement in cell fusion and virus entry ...
Lescar J, Roussel A, Wien MW, Navaza J, Fuller SD, Wengler G, Rey FA: The fusion glycoprotein shell of Semliki Forest virus: an ... Characterization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia viruses. J Virol. 1993 ... Cocquerel L, Voisset C, Dubuisson J: Hepatitis C virus entry: potential receptors and their biological functions. J Gen Virol. ... Conformational change and protein-protein interactions of the fusion protein of Semliki Forest virus. Nature. 2004, 427: 320- ...https://jbiomedsci.biomedcentral.com/articles/10.1186/1423-0127-16-89