*  Pulsed Oral Sirolimus in Autosomal Dominant Polycystic Kidney Disease - Full Text View - ClinicalTrials.gov
Polycystic Kidney, Type 1 Autosomal Dominant Disease Polycystic Kidney, Type 2 Autosomal Dominant Disease Drug: Sirolimus Drug ... Kidney Diseases. Polycystic Kidney Diseases. Polycystic Kidney, Autosomal Dominant. Urologic Diseases. Kidney Diseases, Cystic ... Pulsed Oral Sirolimus in Autosomal Dominant Polycystic Kidney Disease (RAP). The safety and scientific validity of this study ... Riegersperger M, Herkner H, Sunder-Plassmann G. Pulsed oral sirolimus in advanced autosomal-dominant polycystic kidney disease ...
  https://clinicaltrials.gov/ct2/show/NCT02055079?term=pulsed+oral+sirolimus+RAP&rank=1
*  8-Week Study of Tolvaptan Dose Forms in Autosomal Dominant Polycystic Kidney Disease (ADPKD) - Full Text View - ClinicalTrials...
Polycystic Kidney Diseases. Polycystic Kidney, Autosomal Dominant. Kidney Diseases. Urologic Diseases. Kidney Diseases, Cystic ... Kidney Disease. Polycystic Kidney Disease. Autosomal Dominant Polycystic Kidney Disease. PKD. ADPKD. ... Autosomal Dominant Polycystic Kidney Disease Drug: Tolvaptan MR Drug: Tolvaptan IR Drug: Placebo Phase 2 ... 8-Week Study of Tolvaptan Dose Forms in Autosomal Dominant Polycystic Kidney Disease (ADPKD) (NOCTURNE). This study has been ...
  https://clinicaltrials.gov/ct2/show/NCT01451827?cond=%22polycystic+kidney+disease%22&rank=4
*  Autosomal Dominant Polycystic Kidney Disease - American Family Physician
Renal manifestations include varying degrees of kidney injury, urinary tract infections, kidney stones, and hematuria. ... is the most common inherited cause of kidney disease. Enlarging cysts within the kidneys are the clinical hallmark of the ... Epidemiological study of kidney survival in autosomal dominant polycystic kidney disease. Kidney Int. 2003;63(2):678-685. ... Autosomal dominant polycystic kidney disease. Lancet. 2007;369(9569):1287-1301.. 7. Steinman TI. Polycystic kidney disease: a ...
  https://www.aafp.org/afp/2014/0901/p303.html
*  Treatment of autosomal dominant polycystic kidney disease (ADPKD) - Tolvaptan]. | Archivio della ricerca dell'Università degli...
... tolvaptan slowed kidney failure progression (-23%-46% for different objectives) and reduced kidney volume increase and pain ... tolvaptan slowed kidney failure progression (-23%-46% for different objectives) and reduced kidney volume increase and pain ... predicted creatinine clearance 60 mL/min and kidney total volume 750 mL, ... predicted creatinine clearance 60 mL/min and kidney total volume 750 mL, ...
  https://www.iris.unisa.it/handle/11386/4675362
*  Autosomal dominant polycystic kidney disease | The BMJ
When the BMJ last published an editorial on adult autosomal dominant polycystic kidney disease1 there was no chromosomal ... Autosomal dominant polycystic kidney disease. BMJ 1994; 308 doi: https://doi.org/10.1136/bmj.308.6938.1183 (Published 07 May ...
  http://www.bmj.com/content/308/6938/1183
*  Autosomal dominant polycystic kidney disease in children
... the term polycystic kidney disease is reserved for the following hereditary conditions:Autosomal recessive polycystic kidney ... Extrarenal manifestations of autosomal dominant polycystic kidney disease. *Genetics of autosomal dominant polycystic kidney ... Autosomal recessive polycystic kidney disease in children. *Course and treatment of autosomal dominant polycystic kidney ... The incidence of autosomal dominant polycystic kidney disease (ADPKD) is greater than autosomal recessive polycystic kidney ...
  https://www.uptodate.com/contents/autosomal-dominant-polycystic-kidney-disease-in-children
*  Bosutinib For Autosomal Dominant Polycystic Kidney Disease - Study Results - ClinicalTrials.gov
Bosutinib For Autosomal Dominant Polycystic Kidney Disease. This study has been completed. ... Change From Baseline in Kidney Disease Quality of Life (KDQoL)-36 Scale Scores at Month 25 [ Time Frame: Baseline and end of ... Change From Baseline (CFB) in Total Kidney Volume (TKV) at Month 25 [ Time Frame: Baseline and Month 25 (end of Initial ...
  https://clinicaltrials.gov/ct2/show/results/NCT01233869?term=%22High+Blood+Pressure%22&lup_s=03%2F07%2F2013&lup_d=14&show_rss=Y&sel_rss=mod14
*  'polycystic kidney autosomal dominant' Protocols and Video...
Video articles in JoVE about polycystic kidney autosomal dominant include 'Trans-vivo Delayed Type Hypersensitivity Assay for ... Polycystic Kidney, Autosomal Dominant: Kidney disorders with autosomal dominant inheritance and characterized by multiple Cysts ... A p-type semiconductor is formed when doping makes holes that are the dominant charge carrier in the material. An n-type ... In indirect percussion, the plexor finger strikes a pleximeter, which is typically the middle finger of the non-dominant hand ...
  https://www.jove.com/keyword/polycystic+kidney+autosomal+dominant?page=6
*  Renal and extrarenal manifestations of autosomal dominant polycystic kidney disease
The autosomal dominant polycystic kidney disease (ADPKD) belongs to a group of inherited polycystic kidney diseases (1) and is ... study of kidney survival in autosomal dominant polycystic kidney disease. Kidney International, 63: 678-685. [ Links ]. 11. ... 2001). Progression of autosomal-dominant polycystic kidney disease in children. Kidney International, 59: 1654-1662. [ Links ] ... 1998). The association of nephrolithiasis and autosomal dominant polycystic kidney disease. American Journal of Kidney Diseases ...
  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000400014&lng=en&nrm=iso&tlng=en
*  Observational Study in Patients With Autosomal Dominant Polycystic Kidney Disease - Tabular View - ClinicalTrials.gov
Observational Study in Patients With Autosomal Dominant Polycystic Kidney Disease (OVERTURE). The safety and scientific ... Observational Study in Patients With Autosomal Dominant Polycystic Kidney Disease. Official Title A Multi-center, Longitudinal ... Observational Study of Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) to Establish the Rate, ... Total kidney volume ,= 300 cc/m height by ultrasound or ,= 250 cc/m height by MRI ...
  https://clinicaltrials.gov/ct2/show/record/NCT01430494?cond=%22Polycystic+Kidney+Disease%22
*  Axial Spondyloarthritis and Autosomal Dominant Polycystic Kidney Disease in Two Siblings: A Rare Cooccurrence
Autosomal dominant polycystic kidney disease (ADPKD) is the most frequently occurring hereditary kidney disease, and axial ... Autosomal dominant polycystic kidney disease (ADPKD), the most common hereditary kidney disease, is characterized by impaired ... P. A. Gabow, "Autosomal dominant polycystic kidney disease," New England Journal of Medicine, vol. 329, no. 5, pp. 332-342, ... Axial Spondyloarthritis and Autosomal Dominant Polycystic Kidney Disease in Two Siblings: A Rare Cooccurrence. Ozan Volkan ...
  https://www.hindawi.com/journals/crirh/2018/6150875/
*  Risk of intracranial aneurysm bleeding in autosomal-dominant polycystic kidney disease
Patients with autosomal-dominant polycystic kidney disease (ADPKD) carry an increased risk of developing intracranial aneurysms ... Intracranial aneurysms in autosomal dominant polycystic kidney disease. Chauveau, Dominique; Pirson, Yves; Verellen-Dumoulin, ... Rupture of intracranial aneurysm (ICA) is a rare but severe manifestation of autosomal dominant polycystic kidney disease ( ... Home » Risk of intracranial aneurysm bleeding in autosomal-dominant polycystic kidney disease ...
  http://connection.ebscohost.com/c/articles/27488719/risk-intracranial-aneurysm-bleeding-autosomal-dominant-polycystic-kidney-disease
*  Water as Therapy in Autosomal Dominant Polycystic Kidney Disease (ADPKD) - Full Text View - ClinicalTrials.gov
Kidney Diseases. Polycystic Kidney Diseases. Polycystic Kidney, Autosomal Dominant. Urologic Diseases. Kidney Diseases, Cystic ... Water as Therapy in Autosomal Dominant Polycystic Kidney Disease (ADPKD). The safety and scientific validity of this study is ... Water prescription in autosomal dominant polycystic kidney disease: a pilot study. Clin J Am Soc Nephrol. 2011 Jan;6(1):192-7. ... Autosomal dominant polycystic kidney disease (ADPKD) is the most common single gene disorder that is potentially fatal. ADPKD ...
  https://clinicaltrials.gov/ct2/show/NCT00759369?cond=%22polycystic+kidney+disease%22&rank=10
*  Observational Study in Patients With Autosomal Dominant Polycystic Kidney Disease - Full Text View - ClinicalTrials.gov
Kidney Diseases. Polycystic Kidney Diseases. Polycystic Kidney, Autosomal Dominant. Urologic Diseases. Kidney Diseases, Cystic ... Observational Study in Patients With Autosomal Dominant Polycystic Kidney Disease (OVERTURE). The safety and scientific ... A Multi-center, Longitudinal, Observational Study of Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) to ... Total kidney volume ,= 300 cc/m height by ultrasound or ,= 250 cc/m height by MRI ...
  https://clinicaltrials.gov/ct2/show/NCT01430494?cond=%22Polycystic+Kidney+Disease%22&rank=14
*  Sirolimus In Autosomal Dominant Polycystic Kidney Disease And Severe Renal Insufficiency - Tabular View - ClinicalTrials.gov
Autosomal Dominant Polycystic Kidney Disease (ADPKD). Intervention ICMJE *Drug: Sirolimus Patients will be given SRL for one ... Sirolimus In Autosomal Dominant Polycystic Kidney Disease And Severe Renal Insufficiency. Official Title ICMJE EFFECTS OF ... Sirolimus In Autosomal Dominant Polycystic Kidney Disease And Severe Renal Insufficiency (SIRENA-II). This study has been ... Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common hereditary renal disease, responsible for the 8% to 10 ...
  https://clinicaltrials.gov/ct2/show/record/NCT01223755?term=%22High+Blood+Pressure%22&lup_s=01%2F28%2F2013&lup_d=14&show_rss=Y&sel_rss=mod14
*  Mineralocorticoid Antagonism and Endothelial Dysfunction in Autosomal Dominant Polycystic Kidney Disease (ADPKD) - Tabular View...
Mineralocorticoid Antagonism and Endothelial Dysfunction in Autosomal Dominant Polycystic Kidney. Brief Summary The proposed ... Mineralocorticoid Antagonism and Endothelial Dysfunction in Autosomal Dominant Polycystic Kidney Disease (ADPKD). This study ... Mineralocorticoid Antagonism and Endothelial Dysfunction in Autosomal Dominant Polycystic Kidney Disease (ADPKD). ... of blocking aldosterone for improving the health and function of arteries in patients with autosomal dominant polycystic kidney ...
  https://clinicaltrials.gov/ct2/show/record/NCT01853553?term=mineralocorticoid+antagonism&rank=1
*  Sirolimus In Autosomal Dominant Polycystic Kidney Disease And Severe Renal Insufficiency - No Study Results Posted -...
Sirolimus In Autosomal Dominant Polycystic Kidney Disease And Severe Renal Insufficiency (SIRENA-II). This study has been ... Effect of Sirolimus on Disease Progression in Patients with Autosomal Dominant Polycystic Kidney Disease and CKD Stages 3b-4. ...
  https://clinicaltrials.gov/ct2/show/results/NCT01223755?term=%22High+Blood+Pressure%22&lup_s=01%2F28%2F2013&lup_d=14&show_rss=Y&sel_rss=mod14
*  Effect of Statin Therapy on Disease Progression in Autosomal Dominant Polycystic Kidney Disease (ADPKD) - Tabular View -...
Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease, affecting 1 in 400 to 1000 ... Autosomal-dominant polycystic kidney disease in infancy and childhood: progression and outcome. Kidney Int. 2005 Nov;68(5):2218 ... Polycystic Kidney, Autosomal Dominant. Intervention ICMJE *Drug: pravastatin Pravastatin 20 mg daily (subject age 8-12 years) ... Effect of Statin Therapy on Disease Progression in Autosomal Dominant Polycystic Kidney Disease (ADPKD). The safety and ...
  https://clinicaltrials.gov/ct2/show/record/NCT00456365?term=Polycystic+Kidney+Disease&rank=7&view=results
*  8-Week Study of Tolvaptan Dose Forms in Autosomal Dominant Polycystic Kidney Disease (ADPKD) - Full Text View - ClinicalTrials...
Polycystic Kidney Diseases. Polycystic Kidney, Autosomal Dominant. Kidney Diseases. Urologic Diseases. Kidney Diseases, Cystic ... Kidney Disease. Polycystic Kidney Disease. Autosomal Dominant Polycystic Kidney Disease. PKD. ADPKD. ... Autosomal Dominant Polycystic Kidney Disease Drug: Tolvaptan MR Drug: Tolvaptan IR Drug: Placebo Phase 2 ... 8-Week Study of Tolvaptan Dose Forms in Autosomal Dominant Polycystic Kidney Disease (ADPKD) (NOCTURNE). The safety and ...
  https://clinicaltrials.gov/ct2/show/NCT01451827?cond=%22polycystic+kidney+disease%22&rank=2
*  Tolvaptan Phase 3 Efficacy and Safety Study in Autosomal Dominant Polycystic Kidney Disease (ADPKD) - Full Text View -...
Kidney Diseases. Polycystic Kidney Diseases. Polycystic Kidney, Autosomal Dominant. Urologic Diseases. Kidney Diseases, Cystic ... Tolvaptan Phase 3 Efficacy and Safety Study in Autosomal Dominant Polycystic Kidney Disease (ADPKD) (TEMPO3:4). The safety and ... Tolvaptan in autosomal dominant polycystic kidney disease. N Engl J Med. 2013 Mar 28;368(13):1259. doi: 10.1056/NEJMc1300762. ... Tolvaptan in autosomal dominant polycystic kidney disease. N Engl J Med. 2013 Mar 28;368(13):1258-9. doi: 10.1056/NEJMc1300762# ...
  https://clinicaltrials.gov/ct2/show/study/NCT00428948?view=results
*  Somatostatin In Patients With Autosomal Dominant Polycystic Kidney Disease And Moderate To Severe Renal Insufficiency - Full...
Polycystic Kidney Diseases. Polycystic Kidney, Autosomal Dominant. Kidney Diseases. Renal Insufficiency. Urologic Diseases. ... Autosomal Dominant Polycystic Kidney Disease Drug: Octreotide-LAR Other: Saline solution. Phase 3 ... Autosomal Dominant Polycystic Kidney Disease (ADPKD), the most common hereditary cystic renal disease, has an incidence of 1 in ... Somatostatin In Patients With Autosomal Dominant Polycystic Kidney Disease And Moderate To Severe Renal Insufficiency (ALADIN2) ...
  https://clinicaltrials.gov/ct2/show/NCT01377246?cond=%22polycystic+kidney+disease%22&rank=8
*  Rapamycin as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD): The Role of Biomarkers in Predicting a...
Kidney Diseases. Polycystic Kidney Diseases. Polycystic Kidney, Autosomal Dominant. Urologic Diseases. Kidney Diseases, Cystic ... Autosomal Dominant Polycystic Kidney Disease Drug: Rapamycin Other: Standard of Care-Placebo Phase 2 Phase 3 ... Rapamycin as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD): The Role of Biomarkers in Predicting a ... Total Kidney Volume (mL) [ Time Frame: 2 years ]. Secondary Outcome Measures : *Glomerular Filtration Rate (Kidney Function) [ ...
  https://clinicaltrials.gov/ct2/show/NCT00920309?recr=Open&cond=%22Polycystic+Kidney+Diseases%22&rank=11
*  A Long-term Administration Study of OPC-41061 in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) (2) ...
Kidney Diseases, Cystic. Kidney Diseases. Polycystic Kidney Diseases. Polycystic Kidney, Autosomal Dominant. Urologic Diseases ... A Long-term Administration Study of OPC-41061 in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) (2) [ ... A Long-term Administration Study of OPC-41061 in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) (2) [ ... combined renal volume (right and left kidneys) and renal function test [ Time Frame: Every 12 or 48 weeks ]. *adverse events [ ...
  https://clinicaltrials.gov/ct2/show/NCT01022424?cond=%22Kidney+Diseases%2C+Cystic%22&rank=18
*  JCI - Volume 127, Issue 5
... of liver cysts that are radiologically and pathologically identical to those seen in autosomal dominant polycystic kidney ... We also found enrichment on a genome-wide basis of heterozygous mutations in the autosomal recessive polycystic kidney disease ... Autosomal recessive, partial GINS1 deficiency impairs DNA replication and underlies intra-uterine (and postnatal) growth ... This water-conserving mechanism of dietary salt excretion relies on urea transporter-driven urea recycling by the kidneys and ...
  https://hzyouma.com.www.mobile.jci.org/127/5
*  Kidney Institute
... clinical and translational research leading to major advances in the prevention and treatment of kidney diseases. KI Kansas at ... The Kidney Institute at the University of Kansas Medical Center is an internationally recognized, multidisciplinary research ... Xia 'Julie' Zhou on being awarded a NIH K01 grant titled, "Crosstalk of DNMT1 and Sirt1 in Autosomal Dominant Polycystic Kidney ... Xia 'Julie' Zhou on being awarded a AHA grant tittled, "Functional Roles of DNMT1 in Autosomal Dominant Polycystic Kidney ...
  http://www.kumc.edu/school-of-medicine/kidney-institute.html