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*  Phosphatidylinositol metabolism and membrane fusion | Biochemical Journal
... phosphoinositide phosphate; PIP5K, PtdIns4P 5-kinase; PKC, protein kinase C; PLA, phospholipase A; PLC, phospholipase C; PLD, ... Phosphatidylinositol metabolism and membrane fusion. Dominic Poccia, Banafshé Larijani. Biochemical Journal Mar 01, 2009, 418 ( ... Phosphatidylinositol metabolism and membrane fusion Message Subject (Your Name) has forwarded a page to you from Biochemical ...
  http://www.biochemj.org/content/418/2/233
*  phosphatidylinositol-5-phosphate 4-kinase type 2 beta | Phosphatidylinositol phosphate kinases | IUPHAR/BPS Guide to...
Phosphatidylinositol phosphate kinases. Detailed annotation on the structure, function, physiology, pharmacology and clinical ... Phosphatidylinositol phosphate kinases: phosphatidylinositol-5-phosphate 4-kinase type 2 beta. Last modified on 19/08/2015. ... 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta , 1-phosphatidylinositol-5-phosphate 4-kinase B , diphosphoinositide kinase ... phosphatidylinositol-5-phosphate 4-kinase, type II, beta , phosphatidylinositol-5-phosphate 4-kinase ...
  http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2162&familyId=782&familyType=ENZYME
*  ARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating phosphatidylinositol phosphate kinase type Iγ |...
Phosphatidylinositol 4-phosphate 5-kinase type Iγ (PIPKIγ) and synaptojanin 1, the major brain PI(4)phosphate 5-kinase and PI(4 ... phosphatidylinositol (4,5)-bisphosphate; PIPKIγ, phosphatidylinositol 4-phosphate 5-kinase type Iγ; PLD, phospholipase D; SV, ... DTSP, l-phosphatidylinositol 4-phosphate, and total brain lipid extracts were purchased from Sigma-Aldrich; γ[32P]ATP was ... Phosphatidylinositol 4-phosphate 5-kinase α is a downstream effector of the small G protein ARF6 in membrane ruffle formation. ...
  http://jcb.rupress.org/content/162/1/113
*  Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I α | JEM
... phosphatidylinositol 3, 4, 5-trisphosphate; PIPKI, type I phosphatidylinositol phosphate kinase; PIPKIα, α isozyme of PIPKI; ... Type I phosphatidylinositol-4-phosphate 5-kinases are distinct members of this novel lipid kinase family. J. Biol. Chem. 271: ... The phosphatidylinositol phosphate kinases (PIPKs) are enzymes important for PI(4,5)P2 synthesis. There are two types of PIPKs ... Regulation of anaphylactic responses by phosphatidylinositol phosphate kinase type I α. Junko Sasaki, Takehiko Sasaki, Masakazu ...
  http://jem.rupress.org/content/201/6/859
*  Phosphatidylinositol phosphate - Wikipedia
Phosphatidylinositol phosphate may refer to: Phosphatidylinositol 3-phosphate, also known as PI(3)P Phosphatidylinositol 4- ... phosphate, also known as PI(4)P Phosphatidylinositol 5-phosphate, also known as PI(5)P. ...
  https://en.wikipedia.org/wiki/Phosphatidylinositol_phosphate
*  Phosphatidylinositol phosphate kinases - Wikipedia
Phosphatidylinositol phosphate kinases (PIPK) are kinases that phosphorylate the phosphoinositides PtdInsP and PtdInsP2 that ... The activation loop of phosphatidylinositol phosphate kinases determines signaling specificity. Mol Cell 2000 5:1-11. ... Phosphatidylinositol phosphate kinases, a multifaceted family of signalling enzymes. J Biol Chem 1999; 274:9907-9910 Kunz J, ... are derivatives of phosphatidylinositol (PtdIns). It has been found that PtdIns is only phosphorylated on three (3,4,5) of its ...
  https://en.wikipedia.org/wiki/Phosphatidylinositol_phosphate_kinases
*  An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis | JCB
phosphatidylinositol. PI4,5P2. PI 4,5-bisphosphate. PI4P. PI 4-phosphate. PIP4K. PI 5-phosphate 4-kinase. PIP5K. PI4P 5-kinase ... Phosphatidic acid regulates the affinity of the murine phosphatidylinositol 4-phosphate 5-kinase-Ibeta for phosphatidylinositol ... Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis. J. Cell Biol. 169:139-149. doi: ... Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions. Nature. 420:89-93. doi:10.1038/ ...
  http://jcb.rupress.org/content/187/5/701
*  Molecular Cloning and Expression of a Phosphatidylinositol Phosphate Kinase From Rat Retina | IOVS | ARVO Journals
Abstract: : Purpose: Phosphatidylinositol phosphate kinase (PIPK) is an enzyme responsible for the synthesis of PI-4,5-P,sub≷2 ... Y-Z Le, M Agbaga, RE Anderson; Molecular Cloning and Expression of a Phosphatidylinositol Phosphate Kinase From Rat Retina . ... Molecular Cloning and Expression of a Phosphatidylinositol Phosphate Kinase From Rat Retina ... Molecular Cloning and Expression of a Phosphatidylinositol Phosphate Kinase From Rat Retina ...
  https://iovs.arvojournals.org/article.aspx?articleid=2418711
*  Novel phosphatidylinositol phosphate kinases with a G-protein coupled receptor signature are shared by Dictyostelium and...
Novel phosphatidylinositol phosphate kinases with a G-protein coupled receptor signature are shared by Dictyostelium and ... Novel phosphatidylinositol phosphate kinases with a G-protein coupled receptor signature are shared by Dictyostelium and ... Novel phosphatidylinositol phosphate kinases with a G-protein coupled receptor signature are shared by Dictyostelium and ...
  http://www.suddenoakdeath.org/?bibliography=novel-phosphatidylinositol-phosphate-kinases-with-a-g-protein-coupled-receptor-signature-are-shared-by-dictyostelium-and-phytophthora
*  Phosphatidylinositol-4-phosphate 5-kinase (IPR023610) | InterPro | EMBL-EBI
Phosphatidylinositol-4-phosphate 5-kinase (IPR023610) *Phosphatidylinositol-4-phosphate 5-kinase, plant (IPR017163) ... Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members ... Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members ... Phosphatidylinositol-4-phosphate 5-kinase (IPR023610). Short name: PInositol-4-P-5-kinase ...
  http://www.ebi.ac.uk/interpro/entry/IPR023610?q=kinase%20type:family
*  Phosphatidylinositol 4-phosphate - Wikipedia
Phosphatidylinositol 3-phosphate Phosphatidylinositol 5-phosphate Phosphatidylinositol (3,4,5)-trisphosphate Godi A et al., ... Phosphatidylinositol 4-phosphate (PtdIns4P, PI-4-P, PI4P, or PIP) is a precursor of phosphatidylinositol (4,5)-bisphosphate. ... "Lipid Membrane Curvature Induced by Distearoyl Phosphatidylinositol 4-Phosphate". Soft Matter. 8: 3090-3093. doi:10.1039/ ... "Pressure-dependent inverse bicontinuous cubic phase formation in a phosphatidylinositol 4-phosphate/phosphatidylcholine system ...
  https://en.wikipedia.org/wiki/Phosphatidylinositol_4-phosphate
*  PIP4K2A (phosphatidylinositol-5-phosphate 4-kinase, type II, alpha)
... phosphatidylinositol-5-phosphate 4-kinase, type II, alpha), Authors: Keli Lima, João Agostinho Machado-Neto. Published in: ... 4-phosphate 5-kinase activity 1-phosphatidylinositol-5-phosphate 4-kinase activity 1-phosphatidylinositol-5-phosphate 4-kinase ... 4-phosphate 5-kinase activity 1-phosphatidylinositol-5-phosphate 4-kinase activity 1-phosphatidylinositol-5-phosphate 4-kinase ... PIP4K2A (phosphatidylinositol-5-phosphate 4-kinase, type II, alpha). Written. 2015-09. Keli Lima, João Agostinho Machado-Neto. ...
  http://atlasgeneticsoncology.org/Genes/GC_PIP4K2A.html
*  Phosphatidylinositol 5-phosphate - Wikipedia
Type I phosphatidylinositol-4-phosphate 5-kinases synthesize the novel lipids phosphatidylinositol 3,5-bisphosphate and ... Phosphatidylinositol 4-phosphate and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate). Notably, steady-state PtdIns5P ... Phosphatidylinositol 5-phosphate is one of the 7 known cellular phosphoinositides with less understood functions. It is ... Cutting edge: Dok-1 and Dok-2 adaptor molecules are regulated by phosphatidylinositol 5-phosphate production in T cells. J ...
  https://en.wikipedia.org/wiki/Phosphatidylinositol_5-phosphate
*  Pip4k2b MGI Mouse Gene Detail - MGI:1934234 - phosphatidylinositol-5-phosphate 4-kinase, type II, beta
IPR027483 Phosphatidylinositol-4-phosphate 5-kinase, C-terminal. IPR027484 Phosphatidylinositol-4-phosphate 5-kinase, N- ... PIP4K2B, phosphatidylinositol-5-phosphate 4-kinase type 2 beta. Orthology source: HomoloGene, HGNC ... J:205288 Emerling BM, et al., Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53- ... interaction between the juxtamembrane region of the p55 tumor necrosis factor receptor and phosphatidylinositol-4-phosphate 5- ...
  http://www.informatics.jax.org/marker/MGI:1934234
*  Frontiers | Phosphatidylinositol 4-Phosphate 5-Kinases in the Regulation of T Cell Activation | Immunology
... and phosphatidylinositol 3,4,5-triphosphate (PIP3), which are essential for the activation of signalling pathways regulating ... and phosphatidylinositol 3,4,5-triphosphate (PIP3), which are essential for the activation of signalling pathways regulating ... are critical regulators of T cell activation being the main enzymes involved in the synthesis of phosphatidylinositol 4,5- ... are critical regulators of T cell activation being the main enzymes involved in the synthesis of phosphatidylinositol 4,5- ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2016.00186/full
*  Phosphatidylinositol 4-phosphate is a major source of GPCR-stimulated phosphoinositide production | Science Signaling
Phosphatidylinositol 4-phosphate is a major source of GPCR-stimulated phosphoinositide production ... Phosphatidylinositol 4-phosphate is a major source of GPCR-stimulated phosphoinositide production ... Phosphatidylinositol 4-phosphate is a major source of GPCR-stimulated phosphoinositide production ... Phosphatidylinositol 4-phosphate is a major source of GPCR-stimulated phosphoinositide production ...
  http://stke.sciencemag.org/content/11/547/eaan1210.full
*  Phosphatidylinositol 3-phosphate - Wikipedia
Phosphatidylinositol 3-phosphate (PtdIns3P or PI3P) is a phospholipid found in cell membranes that helps to recruit a range of ... D J Gillooly; A Simonsen; H Stenmark (April 15, 2001). "Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain ... It is the product of both the class II and III phosphoinositide 3-kinases (PI 3-kinases) activity on phosphatidylinositol. ...
  https://en.wikipedia.org/wiki/Phosphatidylinositol_3-phosphate
*  Phosphatidylinositol-4-phosphate 3-kinase - Wikipedia
In enzymology, a phosphatidylinositol-4-phosphate 3-kinase (EC 2.7.1.154) is an enzyme that catalyzes the chemical reaction ATP ... The systematic name of this enzyme class is ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 3-phosphotransferase. Other names in ... This enzyme participates in phosphatidylinositol signaling system. As of late 2007, 3 structures have been solved for this ... the two substrates of this enzyme are ATP and 1-phosphatidyl-1D-myo-inositol 4-phosphate, whereas its two products are ADP and ...
  https://en.wikipedia.org/wiki/Phosphatidylinositol-4-phosphate_3-kinase
*  PIK3C2B (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta)
... phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta), Authors: Dessen P. Published in: Atlas Genet ... 1-phosphatidylinositol-4-phosphate 3-kinase activity 1-phosphatidylinositol-4-phosphate 3-kinase activity phosphatidylinositol ... 1-phosphatidylinositol-4-phosphate 3-kinase activity 1-phosphatidylinositol-4-phosphate 3-kinase activity phosphatidylinositol ... phosphate biosynthetic process protein kinase B signaling phosphatidylinositol phosphorylation phosphatidylinositol-mediated ...
  http://atlasgeneticsoncology.org/Genes/GC_PIK3C2B.html
*  Pip4k2c MGI Mouse Gene Detail - MGI:2152214 - phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
IPR027483 Phosphatidylinositol-4-phosphate 5-kinase, C-terminal. IPR027484 Phosphatidylinositol-4-phosphate 5-kinase, N- ... J:75718 Akiba Y, et al., Localization of mRNAs for phosphatidylinositol phosphate kinases in the mouse brain during development ... PIP4K2C, phosphatidylinositol-5-phosphate 4-kinase type 2 gamma. Orthology source: HGNC, HomoloGene ... J:234283 Shim H, et al., Deletion of the gene Pip4k2c, a novel phosphatidylinositol kinase, results in hyperactivation of the ...
  http://www.informatics.jax.org/marker/MGI:2152214
*  Phosphatidylinositol, phosphatidylinositol phosphates and related phosphoinositides: structure, composition, biochemistry, and...
... phosphatidylinositol phosphates and related phosphoinositides: structure, composition, biochemistry, and analysis ... Thus, phosphatidylinositol 4-phosphate, phosphatidylinositol 4,5-bisphosphate, phosphatidylinositol 3-phosphate and ... and phosphatidylinositol 4-phosphate (by PI3K II) to produce phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol ... Phosphatidylinositol 3-phosphate (PI(3)P) and the other phosphatidylinositol monophosphates are present in cells at low levels ...
  http://lipidhome.co.uk/lipids/complex/pi/index.htm
*  Pip5k1c - Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma - Mus musculus (Mouse) - Pip5k1c gene & protein
The majority of PtdIns(4,5)P2 is thought to occur via type I phosphatidylinositol 4-phosphate 5-kinases given the abundance of ... to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). PtdIns(4,5)P2 is involved in a variety of cellular processes and ... is the substrate to form phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3), another second messenger. ... "Phosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brain.". Volpicelli-Daley ...
  https://www.uniprot.org/uniprot/O70161