*  Effects of GABAA receptor antagonist on LTP-like synapt | Open-i
Effects of GABAA receptor antagonist on LTP-like synaptic plasticity in control and VH rats. (A) Representative curves of LFP ... Excitatory Amino Acid Antagonists/pharmacology. *GABA-A Receptor Antagonists/pharmacology. *Male. *Muscle, Skeletal/drug ... Mentions: In separate groups of control (n = 8) and VH rats (n = 10), GABAA receptor antagonist BIC (100 µM) was applied to the ... Mentions: In separate groups of control (n = 8) and VH rats (n = 10), GABAA receptor antagonist BIC (100 µM) was applied to the ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4379994_bht27305&req=4
*  γ-Hydroxybutyrate (GHB)-Induced Respiratory Depression: Combined Receptor-Transporter Inhibition Therapy for Treatment in GHB...
1995) The pharmacology of SCH 50911: a novel, orally-active GABAreceptor antagonist. J Pharmacol Exp Ther 274:1393-1398. ... alone and after pretreatment with the GABAB receptor antagonist SCH50911 (150 mg/kg) and the GABAA receptor antagonist ... a specific GABAB receptor antagonist, (2S)-(+)-5,5-dimethyl-2-morpholineacetic acid (SCH50911), and a specific GABAA receptor ... was administered for inhibition of GABAA receptors and SCH50911 (150 mg/kg) for inhibition of GABAB receptors (three to four ...
  http://molpharm.aspetjournals.org/content/82/2/226
*  Plus it
Pharmacology. To study propagation under reduced inhibition, the noncompetitive GABAA-receptor antagonist picrotoxin (2 μm; ... However, when spontaneous activity in the network was increased by application of the GABAA-receptor antagonist picrotoxin (2 μ ... Reduction in inhibition in the presence of the GABAA receptor antagonist picrotoxin destroys the power law and renders the ... C, Raster plot of LFP activity in response to bath application of the NMDA receptor agonist NMDA and the D1 receptor agonist ...
  http://www.jneurosci.org/content/23/35/11167
*  Neuronal Avalanches in Neocortical Circuits | Journal of Neuroscience
Pharmacology. To study propagation under reduced inhibition, the noncompetitive GABAA-receptor antagonist picrotoxin (2 μm; ... However, when spontaneous activity in the network was increased by application of the GABAA-receptor antagonist picrotoxin (2 μ ... Reduction in inhibition in the presence of the GABAA receptor antagonist picrotoxin destroys the power law and renders the ... C, Raster plot of LFP activity in response to bath application of the NMDA receptor agonist NMDA and the D1 receptor agonist ...
  http://www.jneurosci.org/content/23/35/11167?ijkey=c1a13306114662125f5e8aae2d16422e54eed948&keytype2=tf_ipsecsha
*  The effect of bilateral chronic microinfusion of D-AP5, | Open-i
GABA-A Receptor Antagonists/pharmacology. *Pregnancy. *Rats, Sprague-Dawley. *Receptors, GABA-A/metabolism ... Chronic GABAA receptor antagonism in the MePD from postnatal day 21 for 14 days also advanced puberty, increased socialization ... Chronic GABAA receptor antagonism in the MePD from postnatal day 21 for 14 days also advanced puberty, increased socialization ... Glutamatergic activity also increases in the MePD during puberty without a corresponding γ-aminobutyric acid (GABA)ergic change ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4588820_zee9991581770007&req=4
*  Alcohol- and Alcohol Antagonist-Sensitive Human GABAA Receptors: Tracking δ Subunit Incorporation into Functional Receptors |...
2008) Physiology and pharmacology of alcohol: the imidazobenzodiazepine alcohol antagonist site on subtypes of GABAA receptors ... Alcohol- and Alcohol Antagonist-Sensitive Human GABAA Receptors: Tracking δ Subunit Incorporation into Functional Receptors. ... Alcohol- and Alcohol Antagonist-Sensitive Human GABAA Receptors: Tracking δ Subunit Incorporation into Functional Receptors. ... Alcohol- and Alcohol Antagonist-Sensitive Human GABAA Receptors: Tracking δ Subunit Incorporation into Functional Receptors. ...
  http://molpharm.aspetjournals.org/content/78/5/918
*  GABAB receptor - Wikipedia
... the first GABA(B) receptor antagonist in clinical trials". Biochemical Pharmacology. 68 (8): 1479-87. doi:10.1016/j.bcp.2004.07 ... GABA receptor GABAA receptor GABAA-ρ receptor Chen K, Li HZ, Ye N, Zhang J, Wang JJ (2005). "Role of GABAB receptors in GABA ... Hyland, NP; Cryan, JF (2010). "A Gut Feeling about GABA: Focus on GABA(B) Receptors". Frontiers in Pharmacology. 1: 124. doi: ... GABAB receptors (GABABR) are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA) that are linked via G- ...
  https://en.wikipedia.org/wiki/GABAB_receptor
*  GABAB receptor - Википедија, слободна енциклопедија
... receptor antagonist in clinical trials". Biochemical Pharmacology. 68 (8): 1479-87. PMID 15451390. doi:10.1016/j.bcp.2004.07. ... Kalcijum-detektujući receptorGABA B (1, 2) • Glutamatni receptor (Metabotropni glutamat (1, 2, 3, 4, 5, 6, 7, 8)) • GPRC6A ... GABAB receptori (GABABR) su metabotropni transmembranski receptori za gama-aminobuternu kiselinu (GABA) koji su vezani putem G ... GABAB posredovana promena potencijala je -100 mV, to je znatno više od promene potencijala koju proizvodi GABAA. GABAB ...
  https://sr.wikipedia.org/wiki/GABAB_receptor
*  Pitrazepin - Wikipedia
Murphy VF, Wann KT (November 1988). "The action of GABA receptor agonists and antagonists on muscle membrane conductance in ... Curtis DR, Gynther BD (November 1986). "Pitrazepin: a central glycine and GABA antagonist". European Journal of Pharmacology. ... GABA) receptors in a snail neuron". General Pharmacology. 28 (1): 45-53. doi:10.1016/S0306-3623(96)00152-8. PMID 9112076. Kim ... "Interaction of pitrazepin with the GABA/benzodiazepine receptor complex and with glycine receptors". European Journal of ...
  https://en.wikipedia.org/wiki/Pitrazepin
*  Pharmacology of G Protein Coupled Receptors, Volume 62 - 1st Edition
Purchase Pharmacology of G Protein Coupled Receptors, Volume 62 - 1st Edition. Print Book & E-Book. ISBN 9780123859525, ... the development of receptor antagonists for NMDA, cholinergic muscarinic and bradykinin receptors, and the identification of ... in particular those for GABA. He has also conducted research into the effects of hormones on neurotransmitter receptor function ... Pharmacology, Signaling and Physiological Relevance of the G Protein-coupled Receptor 55 I. Introduction ...
  https://www.elsevier.com/books/pharmacology-of-g-protein-coupled-receptors/neubig/978-0-12-385952-5
*  GABAB Receptors
"γ‐Aminobutyric acid (GABA), the principal inhibitory neurotransmitter in the brain, signals through ionotropic (GABAA/C) and ... 1994) GABA and glutamate release affected by GABAB receptor antagonists with similar potency: no evidence for pharmacologically ... British Journal of Pharmacology 113: 1515-1521. Wojcik WJ and Neff NH (1984) GABAB receptors are negatively coupled to adenylyl ... GABAA/C) and metabotropic (GABAB) receptor systems. GABAB receptors modulate synaptic transmission and are structurally related ...
  http://www.els.net/WileyCDA/ElsArticle/refId-a0000234.html
*  GABAC receptor ion channels. - Semantic Scholar
... develop selective GABAC receptor ligands; and (ii) understand the impact of amino acid changes on GABAC receptor pharmacology ... It concentrates on the structure-activity relationship profiles of the receptor and how these studies were used to: (i) ... 2. Structure-activity relationship studies involving variations of both ligands and their receptor targets are vital to the ... discovery of drugs that interact selectively with particular native and mutant receptor subtypes. Such agents may be useful for ...
  https://www.semanticscholar.org/paper/GABAC-receptor-ion-channels.-Chebib/845d60de212d6a3e10bb8567d48405797f7da929
*  What Is Pharmacology - Flumazenil - Medicalrealm
Flumazenil will act as antagonist to the action of benzodiazepines by competitively bind to the GABA A receptor on the ... Flumazenil will act as antagonist to the action of benzodiazepines by competitively bind to the GABA A receptor on the ... What Is Pharmacology - Flumazenil Flumazenil Flumazenil is useful in treating condition due to overdose of benzodiazepine. ...
  http://www.medicalrealm.net/what-is-pharmacology---flumazenil.html
*  Browse by Ulster Authors and Editors - Ulster Institutional Repository
EFFECTS OF AGONISTS AND ANTAGONISTS AT THE GABA BENZODIAZEPINE RECEPTOR ON CONDITIONED SUPPRESSION IN RATS. PHARMACOLOGY ... Leslie, Julian, Shaw, David, McCabe, C, Reynolds, DS and Dawson, GR (2004) Effects of drugs that potentiate GABA on extinction ... Leslie, Julian (2003) A history of reinforcement: the role of reinforcement schedules in behavior pharmacology. The Behavior ... PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 59 (2). pp. 387-397. [Journal article] ...
  http://uir.ulster.ac.uk/view/author_or_editor/499.html
*  Characterization of the Discriminative Stimulus Effects of the Neuroactive Steroid Pregnanolone in DBA/2J and C57BL/6J Inbred...
Prince RJ and Simmonds MA (1992) 5β-Pregnan-3β-ol-20-one, a specific antagonist at the neurosteroid site of the GABAA receptor ... γ-Aminobutyric acidA receptor α5-subunit creates novel type II benzodiazepine receptor pharmacology. J Neurochem 54: 1802-1804. ... 4A), inactive at GABAA receptors (Purdy et al., 1990; Lambert et al., 1995), and both can act as competitive antagonists of ... Zolpidem has a high affinity for GABAA receptors containing the α1 subunit but lower affinity at receptors containing α4, α5, ...
  http://jpet.aspetjournals.org/content/314/2/675
*  PhD Małgorzata Frankowska - Employees - Institute of Pharmacology - Polish Academy of Sciences
Effects of GABA(B) receptor antagonist, agonists and allosteric positive modulator on the cocaine-induced self-administration ... European journal of pharmacology, 10.1016/j.ejphar.2010.02.010 PMID:20171207 * Effects of imipramine or GABA(B) receptor ... European journal of pharmacology, PMID:17698060 * Effects of GABA(B) receptor agents on cocaine priming, discrete contextual ... The changing world of G protein-coupled receptors: from monomers to dimers and receptor mosaics with allosteric receptor- ...
  http://if-pan.krakow.pl/en/departments/employees/43/PhD-Malgorzata-Frankowska/
*  SKF-97,541 - Wikipedia
... and GABA(B) receptor agonists: time course and differential antagonism by the GABA(B) receptor antagonist 3-aminopropyl( ... and postsynaptic GABAB receptors on neurones in rat brain slices". British Journal of Pharmacology. 101 (4): 949-57. doi: ... Jackson GL; Kuehl D (May 2002). "The GABA(B) antagonist CGP 52432 attenuates the stimulatory effect of the GABA(B) agonist SKF ... and GABAB receptor agonists in mice: differential antagonism by the GABAB receptor antagonist CGP35348". Psychopharmacology. ...
  https://en.wikipedia.org/wiki/SKF-97,541
*  CGP-35348 - Wikipedia
... and GABA(B) receptor agonists: time course and differential antagonism by the GABA(B) receptor antagonist 3-aminopropyl( ... "Functional Pharmacology in Human Brain". Pharmacological Reviews. 58: 162-193. doi:10.1124/pr.58.2.5. Koek W1, Mercer SL, Coop ... and GABAB receptor agonists in mice: differential antagonism by the GABAB receptor antagonist CGP35348". Psychopharmacology. ... CGP-35348 is a compound used in scientific research which acts as an antagonist at GABAB receptors. CGP-35348 was ineffective ...
  https://en.wikipedia.org/wiki/CGP-35348
*  Stimulus-dependent recruitment of lateral inhibition underlies retinal direction selectivity | eLife
Furthermore, the effect of the antagonist cannot be attributed to specific type(s) of GABAergic synapses since GABAA receptors ... Here, we combined pharmacology with the genetic dissection of the GABAergic circuitry to determine the synaptic loci that ... Comparison to previous pharmacological results using GABA receptor antagonist. The role of lateral inhibition onto SACs in ... Adding the GABAA receptor antagonist SR95531 to Slc32a1 KO retinas reduces these direction selectivity parameters for both On ...
  https://elifesciences.org/articles/21053
*  NAVER Academic | Double dissociation between the effects of muscarinic antagonists and benzodiazepine receptor agonists on the...
These results therefore demonstrate a double dissociation between the effects of muscarinic antagonists and BZR agonists on the ... and benzodiazepine receptor (BZR) agonists, such as diazepam, produce a reliable impairment in the performance of one trial ... with the effects of two muscarinic antagonists, scopolamine (0, 0.6, 0.8 and 1.0 mg/kg, SC) and atropine (0, 15, 30 and 60 mg/ ... GABA-A Receptor Agonists, Lorazepam, Male, Memory, Muscarinic Antagonists, Rats, Rats, Wistar, Scopolamine Hydrobromide. ...
  http://academic.naver.com/article.naver?doc_id=139549764
*  A comparison of GABAC and ρ subunit receptors from the white perch retina | Visual Neuroscience | Cambridge Core
A comparison of GABAC and ρ subunit receptors from the white perch retina - Volume 14 Issue 5 - Aohua Qian, George Hyatt, ... I4AA acts as a partial agonist on perch-s receptors whereas it is strictly an antagonist on native GABAC receptors. Picrotoxin ... Feigenspan A., Wassle H. & Bormann J. (1993). Pharmacology of GABA receptor C1− channels in rat retinal bipolar cells. Nature ... but both competitive and noncompetitive on GABAC receptors. We conclude that GABAC receptors are formed by GABA p subunits but ...
  https://www.cambridge.org/core/journals/visual-neuroscience/article/comparison-of-gabac-and-subunit-receptors-from-the-white-perch-retina/EA41F8F31BF921FC387B0C128608AE32
*  Clobenpropit - Wikipedia
It has neuroprotective effects via stimulation of GABA release in the brain. H3 receptor antagonist Sahlholm K, Nilsson J, ... European Journal of Pharmacology. 567 (3): 206-210. doi:10.1016/j.ejphar.2007.04.032. PMID 17537431. Dai H, Fu Q, Shen Y, Hu W ... Zhang Z, Timmerman H, Leurs R, Chen Z (2007). "The histamine H3 receptor antagonist clobenpropit enhances GABA release to ... Clobenpropit is a histamine H3 receptor antagonist. ... "The human histamine H3 receptor couples to GIRK channels in ...
  https://en.wikipedia.org/wiki/Clobenpropit
*  CGP-7930 - Wikipedia
2006 Apr;50(5):632-9. PMID 16406445 Filip M, Frankowska M, Przegaliński E. Effects of GABA(B) receptor antagonist, agonists and ... In vivo effectiveness of CGP7930, a positive allosteric modulator of the GABAB receptor. European Journal of Pharmacology. 2004 ... The GABA(B) receptor allosteric modulator CGP7930, like baclofen, reduces operant self-administration of ethanol in alcohol- ... a positive allosteric modulator of the GABA(B) receptor. Journal of Biological Chemistry. 2004 Jul 9;279(28):29085-91. PMID ...
  https://en.wikipedia.org/wiki/CGP-7930
*  Imidazenil - Wikipedia
Behavioural Pharmacology. 1995 Jun;6(4):323-332. Auta J, Costa E, Davis JM, Guidotti A. Imidazenil: an antagonist of the ... Comparison of the effects of full and partial allosteric modulators of GABA(A) receptors on complex behavioral processes in ... Anxioselective compounds acting at the GABA(A) receptor benzodiazepine binding site. Current Drug Targets. CNS and Neurological ... Rump S, Gidynska T, Galecka E, Antkowiak O, Nawrocka M, Kowalczyk M. Effects of imidazenil, a new benzodiazepine receptor ...
  https://en.wikipedia.org/wiki/Imidazenil
*  Pharmacology of Caffeine | SpringerLink
... receptor agonist and antagonist on spatial learning and memory. European Journal of Pharmacology, 249, 271-280.CrossRefGoogle ... and GABA, receptors and calcium channels in mouse brain. Cellular and Molecular Neurobiology 13, 247-261.PubMedCrossRefGoogle ... dopamine receptor antagonists block caffeine-induced stimulation of locomotor activity in rats. Pharmacology, Biochemistry and ... Caffeine and theophylline as adenosine receptor antagonists in humans. Journal of Pharmacology and Experimental Therapeutics, ...
  https://link.springer.com/chapter/10.1007/978-1-4757-2913-9_5