High-Intensity Focused Ultrasound Therapy in Treating Patients With Localized Prostate Cancer
RATIONALE: High-intensity focused ultrasound energy may be able to kill tumor cells by heating them without affecting normal ... Primary. - To determine patient acceptability, feasibility, and side-effect profile by evaluating. records of adverse events.. ... To determine the effectiveness of therapy by post-treatment transrectal. ultrasound-guided biopsies at 6 months and if there is ... OUTLINE: Patients undergo hemiablation using high-intensity focused ultrasound to the side. of the prostate with cancer and up ...http://www.knowcancer.com/cancer-trials/NCT00561262/
Primary whole‐gland ablation for localized prostate cancer with high‐intensity focused ultrasound: The important predictors of...
... gland ablation for localized prostate cancer with high‐intensity focused ultrasound: The important predictors of biochemical ... Transrectal high‐intensity focused ultrasound for treatment of patients with stage T1b‐2n0 m0 localized prostate cancer: a ... Primary whole-gland ablation for localized prostate cancer with. high-intensity focused ultrasound: The important predictors of ... Results: Among 182 patients, 26.9% had prostate-speciﬁc antigen biochemical. recurrence after high-intensity focused ultrasound ...https://www.deepdyve.com/lp/wiley/primary-whole-gland-ablation-for-localized-prostate-cancer-with-high-dUns369Ous
Patent US6643535 - System for providing computer guided ablation of tissue - Google Patents
An imaging device receives imaging data from a treatment region of a patient, processes the imaging data and provides imaging ... Other ablative elements may include, for example, radio frequency devices, microwave devices, high intensity focused ultrasound ... The transrectal ultrasound probe 48 is used to visualize the prostate and the cryosurgical probes. A stepper assembly 50 ... In a primary application of the present invention the ablative devices 38 are cryosurgical probes, as will be explained in ...http://www.google.com/patents/US6643535?dq=6101531
Diagnostic Performance of Biparametric MRI for Detection of Prostate Cancer: A Systematic Review and Meta-Analysis.
Ultrasound, High-intensity Focused, Transrectal. Tissue ablation of the PROSTATE performed by ultrasound from a transducer ... PET/CT Imaging Study of the Safety and Diagnostic Performance of [68Ga]RM2 in Patients With Primary Prostate Cancer ... A performance measure for rating the ability of a person to perform usual activities, evaluating a patient's progress after a ... Radiology is the branch of medicine that studies imaging of the body; X-ray (basic, angiography, barium swallows), ultrasound, ...https://www.bioportfolio.com/resources/pmarticle/2068907/Diagnostic-Performance-of-Biparametric-MRI-for-Detection-of-Prostate-Cancer-A-Systematic.html
High-intensity Focused Ultrasound Offers New Opportunities | Imaging Technology News
The emerging technology of focused ultrasound expands into many treatment areas as a noninvasive alternative to surgery, ... The patient's head also is shaved to permit the transference of ultrasound waves. ... "The primary argument against targeted treatment for the prostate is that the disease is multifocal," Napoli explained. He said ... He said a special FUS transrectal transducer has been created so it can be placed against the rectal wall, next to the prostate ...https://www.itnonline.com/article/high-intensity-focused-ultrasound-offers-new-opportunities
Rectal wall MRI radiomics in prostate cancer patients: Prediction of and correlation with early rectal toxicity.
Ultrasound, High-intensity Focused, Transrectal. Tissue ablation of the PROSTATE performed by ultrasound from a transducer ... Intravoxel Incoherent Motion Diffusion-Weighted Imaging of Primary Rectal Carcinoma: Correlation with Histopathology. ... Since the advent of prostate-specific antigen (PSA)-based testing, transrectal ultrasound (TRUS)-guided prostate biopsy has ... prostate cancer patients: Prediction of and correlation with early rectal toxicity.". To investigate MRI radiomic analysis to ...https://www.bioportfolio.com/resources/pmarticle/2089233/Rectal-wall-MRI-radiomics-in-prostate-cancer-patients-Prediction-of-and-correlation.html
Benign prostatic hyperplasia and prostate J. Sausville, M. Naslund
High intensity focused ultrasound in the treatment of primary prostate cancer: the first UK series. Br J Cancer 2009; 101: 19- ... Cryotherapy delivered by a transperineal route under Transrectal ultrasound (TRUS) guidance has been described for both primary ... Limitations included high utilisation of screening by patients in the control arm, producing more diagnoses of prostate cancer ... High-intensity focused ultrasound: ready for primetime. Urol Clin N Am 2010; 37: 27-35. 51 Finley DS, Pouliot F, Miller DC, ...http://spotidoc.com/doc/18083/light-start-breakfast-more%E2%80%A6-lunch--after
Preoperative Radiation Therapy for High Risk Prostate Cancer
This is a Phase I dose-escalation study of moderate dose radiation therapy prior to radical prostatectomy for patients with... ... Ultrasound, High-intensity Focused, Transrectal. Tissue ablation of the PROSTATE performed by ultrasound from a transducer ... prostatectomy for patients with high-risk localized disease. Its hypothesis is that such treatment will be well tolerated with ... Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: ...https://www.bioportfolio.com/resources/trial/69373/Preoperative-Radiation-Therapy-for-High-Risk-Prostate-Cancer.html
Sonography After Thoracic Surgery (SATS)
Ultrasound, High-intensity Focused, Transrectal. Tissue ablation of the PROSTATE performed by ultrasound from a transducer ... sequencing assisted in establishing the diagnosis and treatment for a Chinese patient with breast and lung multiple primary ... the patient using the ultrasound machine in order to learn from his or her mistake. Management decisions regarding patient care ... Thoracic ultrasound evaluation of the chest will occur in the same time sequence as CXR for all patients enrolled in the study ...https://www.bioportfolio.com/resources/trial/63399/Sonography-After-Thoracic-Surgery-SATS.html
Ultrasound in Treating Patients With Prostate Cancer Confined to the Prostate
Highly focused ultrasound energy may be able to kill cancer cells by heating the tumor without affecting the surrounding tissue ... High-intensity focused ultrasound (HIFU) energy using. the Sonablate system is delivered to the prostate tissue over ... Able to visualize prostate gland adequately on transrectal ultrasound imaging. - No prostate calcification greater than 5 mm. ... Primary Purpose: Treatment. Principal Investigator. Michael O. Koch, MD. Investigator Role:. Study Chair ...http://www.knowcancer.com/cancer-trials/NCT00030290/
Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer - Full Text View -...
No prior radical surgery (prostatectomy), high-intensity focused ultrasound, or cryosurgery for prostate cancer ... Patients undergoing brachytherapy must have transrectal ultrasound confirmation of prostate volume , 60 cc, American Urological ... Primary. *Demonstrate an overall survival (OS) advantage in patients with intermediate-risk prostate cancer treated with dose- ... Patients undergo external-beam radiation therapy (EBRT) once daily on days 1-5. Some patients instead receive EBRT with high- ...https://clinicaltrials.gov/ct2/show/NCT00936390?term=NCT+00936390&rank=1
Prostate Cancer Signs, Causes, Treatment & Stages
Cryotherapy and high-intensity focused ultrasound (HIFU) have been used to destroy tissue, either by freezing or by generating ... Symptom palliation: The primary approach to the management of symptoms in patients with advanced prostate cancer is systemic ... This procedure utilizes transrectal ultrasound that is highly focused into a small area, creating intense heat of 80° C to 100 ... HIFU (high-intensity focused ultrasound) was first developed as a treatment for benign prostatic hyperplasia (BPH) and is now ...https://www.emedicinehealth.com/prostate_cancer/article_em.htm
Magnetic resonance-guided high-intensity focused ultrasound combined with radiotherapy for palliation of head and neck cancer-a...
A recent prospective development study of 42 patients utilized MRI mapping and trans-rectal HIFU ablation of prostate tumours ... Primary objectives. The primary aim of this study is to assess safety, toxicity and feasibility of MRg-HIFU treatments to the ... High-intensity focused ultrasound for prostate cancer: a systematic review. Clin Oncol (R Coll Radiol). 2011;23:117-27.Google ... Magnetic resonance-guided high-intensity focused ultrasound (MRg-HIFU) is a novel technique in the treatment of cancer that has ...https://jtultrasound.biomedcentral.com/articles/10.1186/s40349-016-0055-x
Maislos SD, Knauer C, Grunberger i: High intensity focused ultrasound for treatment of BPH. 19TH Workd Congress of Endourology ... Primary bladder neck dysfunction in children and adolescents: results of long term alpha blocker therapy. J. Urol. 181, #4, ... Schachter LR, Raboy A, Albert P: Brachytherapy in patients 60 years of age or less with minimum four year follow-up. J. Urol. ... when atypical glands are found on initial transrectal prostate biopsy. J. Urol 163, #4, Supplement, Abstract # 1241. ...http://www.downstate.edu/urology/Research.html
SonaCare Medical Partners with University College London to Create Center of Excellence for HIFU Surgical Ablation ... ( ...
CHARLOTTE N.C. May 2 2013 /-...According to Mark Emberton MD Directo... The highly precise Sonablate 500 HIFU transrectal s... ... SonaCare Medical, with its subsidiary Focus Surgery, Inc., designs and manufactures high intensity focused ultrasound (HIFU) ... "The highly precise Sonablate 500 HIFU transrectal system has already proven an effective way to transition from treating the ... The Center of Excellence will provide physician training and proctoring along with clinical studies, patient satisfaction ...http://www.bio-medicine.org/medicine-technology-1/SonaCare-Medical-Partners-with-University-College-London-to-Create-Center-of-Excellence-for-HIFU-Surgical-Ablation-Technology-32610-1/
Alternative Treatments | Central Florida Prostate Care
While we focus on the HIFU procedure, we do offer other methods of prostate cancer treatment. If you'd like more information, ... High Intensity Focused Ultrasound. HIFU with the Sonablate® 500 is a non invasive treatment option for prostate cancer that ... uses a transrectal probe to focus ultrasound waves in the prostate. In the focal zone, the temperature is rapidly elevated ... Some patients are choosing no treatment at all, or active surveillance, because of the effects on quality of life after ...http://www.hifucare.com/alternative-prostate-cancer-treatments
ELEVEN THINGS TO KNOW ABOUT PROSTATE CANCER
High-intensity focused ultrasound therapy has been used as a primary therapy in patients with localized prostate cancer not ... Destruction of cells through rapid freezing and thawing using transrectal guided placement of probes and injection of freezing/ ... High-intensity focused ultrasound therapy. There were no data from randomized trials comparing HIFU with other primary ... high-intensity focused ultrasound (HIFU), proton beam radiation therapy, or intensity modulated radiation therapy (IMRT) (0 ...http://healthfully.org/cvt/id6.html
Indian Journal of Urology: Table of Contents
Transrectal high-intensity focused ultrasound for the treatment of prostate cancer: Past, present, and future. p. 4. ... and in patients with bulky metastatic disease (≥CS IIb) due to their high risk of systemic disease and recurrence. Primary ... Upon a review of recently published articles on high-intensity focused ultrasound (HIFU) in the treatment of prostate cancer, ... patients. Follow-up renograms were available in 74 patients who showed improvement in drainage in 69 patients and obstructed ...http://www.indianjurol.com/showBackIssue.asp?issn=0970-1591
MRI Targeted Focal Laser Thermal Therapy of Prostate Cancer
... high-intensity focused... ... The primary purpose of this study is to evaluate the ... of MRI guided focal prostate cancer laser ablation in patients with a focus of prostate cancer who has not yet received ... Targeted Prostate Biopsy Using a Novel MRI-Ultrasound Fusion Device. The purpose of this study is to evaluate the effectiveness ... At visit 3, 12 cores transrectal us guided prostate biopsy will confirm yet again that this is a unilateral, unifocal ...https://www.bioportfolio.com/resources/trial/66506/MRI-Targeted-Focal-Laser-Thermal-Therapy-of-Prostate-Cancer.html
Patent US6413216 - Method and assembly for performing ultrasound surgery using cavitation - Google Patents
... cavitation induced by an ultrasound beam for creating a controlled surgical lesion in a selected treatment volume of a patient ... and a low frequency ultrasound beam may be used to cavitate the microbubbles within the treatment volume without causing damage ... and then the microbubbles in the treatment volume are cavitated with the ultrasound beam to create the controlled surgical ... 6a or 6 b, but by increasing all element drive amplitudes, the high intensity ultrasound beam 42 will focus at that same ...http://www.google.com/patents/US6413216?dq=5,581,513
Publications - Professor Hashim Ahmed
... and Patient Reported Outcomes in Patients Treated With Salvage Radiation Following Primary High Intensity Focal Ultrasound for ... WG cryotherapy was used in 2 studies, WG high-intensity focused ultrasound (HIFU) in 5, focal cryotherapy in 2, focal HIFU in 3 ... Development and Phantom Validation of a 3-D-Ultrasound-Guided System for Targeting MRI-Visible Lesions During Transrectal ... magnetic resonance imaging parameters for assessing oncological outcomes after high intensity-focused ultrasound focal therapy ...http://www.imperial.ac.uk/people/hashim.ahmed/publications.html
Prostate Cancer Guidelines: Guidelines Summary, Multiparametric Magnetic Resonance Imaging , Management of Clinically Localized...
... should inform low-risk prostate cancer patients who are considering focal therapy or high-intensity focused ultrasound (HIFU) ... Clinicians should not recommend primary ADT for patients with high-risk localized prostate cancer unless the patient has both ... At least a 12-core confirmatory transrectal ultrasound (TRUS)-guidedbiopsy (including anterior directed cores) within 6 to 12 ... Murat FJ, Gelet A. Current status of high-intensity focused ultrasound for prostate cancer: technology, clinical outcomes, and ...https://emedicine.medscape.com/article/1967731-guidelines
HIFU | Modern medicine
High-intensity focused ultrasound as salvage therapy allows for intermediate-term disease control in selected patients with ... Transrectal HIFU shows a statistically significant increase in per-core negative biopsy rates. ... Oncologic outcomes are similar using focal cryotherapy and focal high-intensity focused ultrasound for treatment of localized ... The Sonablate 450, SonaCare Medical's high-intensity focused ultrasound (HIFU) device, has received FDA clearance for prostate ...http://www.modernmedicine.com/tag/hifu
Kudos - helping increase the reach and impact of research
Short-term outcome after high-intensity focused ultrasound in the treatment of patients with high-risk prostate cancer. ... Editorial Comment on: First Analysis of the Long-Term Results with Transrectal HIFU in Patients with Localized Prostate Cancer ... Impact of Smoking and Smoking Cessation on Oncologic Outcomes in Primary Non-muscle-invasive Bladder Cancer. Published in: ... and other immunomarkers in the detection of adenocarcinoma in prostatic tissue damaged by high intensity focused ultrasound the ...https://www.growkudos.com/profiles/7023
Soy Protein Supplement in Preventing Prostate Cancer in Patients With Elevated Prostate-Specific Antigen Levels
Soy protein supplement may prevent or delay the development of prostate cancer in patients who have elevated pro... ... Ultrasound, High-intensity Focused, Transrectal. Tissue ablation of the PROSTATE performed by ultrasound from a transducer ... Allocation: Randomized, Control: Placebo Control, Masking: Double-Blind, Primary Purpose: Prevention. Conditions. Prostate ... Isoflavones and Radiation Therapy in Treating Patients With Localized Prostate Cancer. RATIONALE: Eating a diet high in soy ...https://www.bioportfolio.com/resources/trial/123095/Soy-Protein-Supplement-in-Preventing-Prostate-Cancer-in-Patients-With-Elevated-Prostate.html