*  Carboplatin and Paclitaxel With or Without Bevacizumab Compared to Docetaxel, Carboplatin, and Paclitaxel in Treating Patients...
MTD of IV paclitaxel with IP carboplatin and IV bevacizumab followed by IP paclitaxel, determined according to dose-limiting ... Patients receive IP carboplatin on day 1, paclitaxel IV on day 1, and IP paclitaxel on day 8 in course 1 as in part A dose- ... FEASIBILITY PHASE (PART C): Patients receive IP carboplatin on day 1, paclitaxel IV on day 1, and IP paclitaxel on day 8 in ... Carboplatin and Paclitaxel With or Without Bevacizumab Compared to Docetaxel, Carboplatin, and Paclitaxel in Treating Patients ...
  https://clinicaltrials.gov/ct2/show/NCT00085358?cond=%22Adenocarcinoma+of+the+appendix%22&rank=10
*  Paclitaxel and Carboplatin With or Without Bevacizumab in Treating Patients With Stage II, Stage III, or Stage IV Ovarian...
To compare the weekly paclitaxel to the every-3-week paclitaxel with respect to the incidence of severe or serious adverse ... To compare the weekly paclitaxel to the every-3-week paclitaxel with respect to patients' self-reported quality of life (QOL) ... A Phase III Trial of Every-3-Weeks Paclitaxel Versus Dose Dense Weekly Paclitaxel in Combination With Carboplatin With or ... I. To determine if the weekly paclitaxel increases the duration of overall survival compared to the every-3-week paclitaxel ...
  https://clinicaltrials.gov/ct2/show/record/NCT01167712?show_desc=Y
*  Resistance to Paclitaxel Is Proportional to Cellular Total Antioxidant Capacity | Cancer Research
P , 0.001, paclitaxel versus paclitaxel plus SOD. C, cells were treated (solid columns) or untreated (open columns) with 0.02 ... This theory is confirmed by our data showing that (a) paclitaxel induced the production of O2−, H2O2 and NO; (b) paclitaxel ... regardless whether they are paclitaxel sensitive or paclitaxel resistant. These results suggest that paclitaxel ... P , 0.001, paclitaxel versus paclitaxel plus antioxidant. B, cells were treated for 2 hours with 100 milliunits SOD and/or 0.04 ...
  http://cancerres.aacrjournals.org/content/65/18/8455?ijkey=7846fdcef81302dfadeb2b51f1be84207bab1fed&keytype2=tf_ipsecsha
*  Carboplatin/Paclitaxel Appears To Be as Effective as Cisplatin/Paclitaxel in Ovarian Cancer | Cancer Network | The Oncology...
... paclitaxel as first-line treatment in ovarian cancer found significantly less toxicity with carboplatin/paclitaxel, with no ... either cisplatin/paclitaxel or carboplatin/paclitaxel. Paclitaxel. (185 mg/m²) was given as a 3-hour infusion. Cisplatin was ... between cisplatin/paclitaxel and carboplatin/paclitaxel.. To date, he said, there have been 253 events in GOG-158, an. ... Carboplatin/Paclitaxel Appears To Be as Effective as Cisplatin/Paclitaxel in Ovarian Cancer ...
  http://www.cancernetwork.com/articles/carboplatinpaclitaxel-appears-be-effective-cisplatinpaclitaxel-ovarian-cancer
*  Paclitaxel - Wikipedia
Albumin-bound paclitaxel (trade name Abraxane, also called nab-paclitaxel) is an alternative formulation where paclitaxel is ... Space-filling model of paclitaxel Rotating paclitaxel molecule model Crystal structure of paclitaxel Total charge surface of ... Moreover, Paclitaxel has been used in vitro to inhibit insulin fibrillation; in a molar ratio of 10:1 (insulin:paclitaxel), it ... Paclitaxel is one of several cytoskeletal drugs that target tubulin. Paclitaxel-treated cells have defects in mitotic spindle ...
  https://en.wikipedia.org/wiki/Paclitaxel
*  DHA-paclitaxel - Wikipedia
The advantage of DHA-paclitaxel over paclitaxel is DHA-paclitaxel's ability to carry much higher concentrations of paclitaxel ... DHA-paclitaxel (or Taxoprexin) is an investigational drug (from Protarga Inc) made by linking paclitaxel to docosahexaenoic ... With increased activity, DHA-paclitaxel, also known as Taxoprexin, may have a more successful response in cancer patients than ... "A phase II open-label study of DHA-paclitaxel (Taxoprexin) by 2-h intravenous infusion in previously untreated patients with ...
  https://en.wikipedia.org/wiki/DHA-paclitaxel
*  Protein-bound paclitaxel - Wikipedia
Protein-bound paclitaxel, also known as nanoparticle albumin-bound paclitaxel or nab-paclitaxel, is an injectable formulation ... Stinchcombe, Thomas E (2007). "Nanoparticle albumin-bound paclitaxel: a novel Cremphor-EL®-free formulation of paclitaxel". ... In this formulation, paclitaxel is bonded to albumin as a delivery vehicle. It is manufactured and sold in the United States by ... "Paclitaxel (Abraxane)". U.S. Food and Drug Administration. 11 October 2012. Retrieved 10 December 2012. Resolution 9190, ...
  https://en.wikipedia.org/wiki/Protein-bound_paclitaxel
*  Paclitaxel total synthesis - Wikipedia
Paclitaxel total synthesis in organic chemistry is a major ongoing research effort in the total synthesis of paclitaxel (Taxol ... "Synthesis of Paclitaxel. 1. Synthesis of the ABC Ring of Paclitaxel by SmI2-Mediated Cyclization" Organic Letters 17 (11), 2570 ... but it also opens the way to paclitaxel derivatives not found in nature but with greater potential. The paclitaxel molecule ... Paclitaxel Total Syntheses @ SynArchive.com Taxolog for Taxol research, founded by Holto The complete Taxol story from Chemical ...
  https://en.wikipedia.org/wiki/Paclitaxel_total_synthesis
*  Paclitaxel | SpringerLink
A Case of Albumin-Bound Paclitaxel-Induced Peripheral Neuropathy without Exacerbation]. Gan to Kagaku Ryoho 44: 517-519, No. 6 ...
  https://link.springer.com/article/10.1007/s40278-017-37379-4
*  Cipla-Paclitaxel - Drugs.com
A list of US medications equivalent to Cipla-Paclitaxel is available on the Drugs.com website. ... Cipla-Paclitaxel is a medicine available in a number of countries worldwide. ... Ingredient matches for Cipla-Paclitaxel. Paclitaxel. Paclitaxel is reported as an ingredient of Cipla-Paclitaxel in the ... Cipla-Paclitaxel. Cipla-Paclitaxel may be available in the countries listed below. ...
  https://www.drugs.com/international/cipla-paclitaxel.html
*  Paclitaxel (taxol) - PubMed - NCBI
Paclitaxel (taxol). Rowinsky EK1, Donehower RC.. Author information. 1. Division of Pharmacology and Experimental Therapeutics ...
  https://www.ncbi.nlm.nih.gov/pubmed/7885406
*  Paclitaxel
... paclitaxel) Injection should be administered under the supervision of a physician experienced in the use of cancer ... Paclitaxel is a white to off- white crystalline powder with the empirical formula C47H51NO14 and a molecular weight of 853.9. ... Paclitaxel is a natural product with antitumor activity. TAXOL is obtained via a semi-synthetic process from Taxus baccata. The ... TAXOL® (paclitaxel) Injection should be administered under the supervision of a physician experienced in the use of cancer ...
  http://www.egeneralmedical.com/rxlist00000073.html
*  Abitaxel (Paclitaxel) Teva
Abitaxel information about active ingredients, pharmaceutical forms and doses by Teva, Abitaxel indications, usages and related health products lists
  http://drugs-about.com/drugs-a/abitaxel.html
*  Patent US5473055 - Polymer-bound paclitaxel derivatives - Google Patents
... are endowed with antitumor activity and show improved water solubility and decreased toxicity in comparison with paclitaxel or ... of units containing the paclitaxel and paclitaxel derivatives is from 0.5 to 2, more preferably, the content of paclitaxel in ... The paclitaxel content was 4% w/w%.. EXAMPLE 7. 2',7-di(carbobenzyloxy-β-alanyl)paclitaxel. To a solution of 200 mg of ... Water soluble paclitaxel prodrugs. US20080153865 *. Oct 29, 2007. Jun 26, 2008. Pg-Txl Company, L.P.. Water soluble paclitaxel ...
  http://www.google.com/patents/US5473055?dq=6,081,786
*  Paclitaxel - Paclitaxel Manufacturer, Supplier & Exporter
... paclitaxel dealers, suppliers, traders & exporters. Listed manufacturing companies are offering wide range of paclitaxel with ... Paclitaxel Paclitaxel is a used in . It was discovered in a program at the in 1967 when and isolated it from the bark of the ... Paclitaxel Paclitaxel, a potent disruptor of microtubules derived from the bark of the Pacific yew tree, is widely used as a ... Paclitaxel Paclitaxel is now used to treat patients with lung, ovarian, breast, head and neck cancer, and advanced forms of ...
  https://www.tradeindia.com/manufacturers/paclitaxel.html
*  Paclitaxel & carboplatin - Information and support - Macmillan Cancer Support
If you or someone close to you has been diagnosed with cancer, you're not alone. Find out what to expect, get information, practical advice and support, hear from experts and read about other people's experiences.
  https://www.macmillan.org.uk/information-and-support/lung-cancer/small-cell-lung-cancer/treating/chemotherapy/drugs-and-combination-regimens/combination-chemotherapy/paclitaxel-and-carboplatin.html
*  Phase I Study of Weekly LOC-paclitaxel Injection
The goal of this clinical research study is to find the highest tolerable dose of LOC-paclitaxel when given to patients with ... 3. To measure the plasma pharmacokinetics of LOC-paclitaxel and paclitaxel derived from LOC-paclitaxel in patients receiving ... The goal of this clinical research study is to find the highest tolerable dose of LOC-paclitaxel when given to patients with ... Part I 1. To determine the recommended dose of LOC-paclitaxel as a single agent, given weekly, 5/6 weeks. 2. To determine the ...
  https://www.mdanderson.org/patients-family/diagnosis-treatment/clinical-trials/clinical-trials-index/clinical-trials-detail.ID2009-0432.html
*  Paclitaxel Albumin-stabilized Nanoparticle Formulation - National Cancer Institute
This page contains brief information about paclitaxel albumin-stabilized nanoparticle formulation and a collection of links to ... Paclitaxel albumin-stabilized nanoparticle formulation is a form of paclitaxel contained in nanoparticles (very tiny particles ... This form may work better than other forms of paclitaxel and have fewer side effects. For more information about paclitaxel ... Paclitaxel albumin-stabilized nanoparticle formulation is approved to be used alone or with other drugs to treat:. *Breast ...
  https://www.cancer.gov/about-cancer/treatment/drugs/nanoparticlepaclitaxel
*  Paclitaxel-Triazine Dendrimer Constructs: Efficacy, Toxicity, and Characterization | SpringerLink
... a phase III randomized trial of paclitaxel poliglumex versus paclitaxel in chemotherapy-naive women with advanced-stage non- ... The discussion is restricted to our efforts in paclitaxel-laden constructs, an area that we have had the most success and have ... Bonomi P (2007) Paclitaxel poliglumex (PPX, CT-2103): macromolecular medicine for advanced non-small-cell lung cancer. Expert ... El Alaoui A, Saha N, Schmidt F, Monneret C, Florent J-C (2006) New Taxol (paclitaxel) prodrugs designed for ADEPT and PMT ...
  https://link.springer.com/chapter/10.1007/978-1-4614-2305-8_5
*  Paclitaxel Clinical Trials - Vanderbilt-Ingram Cancer Center
Three-Arm Randomized Phase II Study of Carboplatin and Paclitaxel in Combination with Cetuximab, IMC-A12 or Both for Advanced ... A Phase Ib Trial of LY2157299 (TGFβR1 Kinase Inhibitor) with Paclitaxel in Patients with Triple Negative Metastatic Breast ... A Randomized Phase III Trial Comparing Conventional-Dose Chemotherapy Using Paclitaxel, Ifosfamide, and Cisplatin (TIP) with ... High-Dose Chemotherapy Using Mobilizing Paclitaxel plus Ifosfamide followed by High-Dose Carboplatin and Etoposide (TI-CE) as ...
  http://www.vicc.org/ct/protocols.php?drug-id=3325&drug-name=Paclitaxel
*  PACLITAXEL Prescription Assistance Programs | PharmacyChecker.com
Prescription assistance can help you obtain free or low-cost PACLITAXEL. ... Get PACLITAXEL prescription assistance program information from Pharmacy Checker. ...
  https://www.pharmacychecker.com/patient-assistance-programs/paclitaxel
*  Apo Paclitaxel - PROXIM
APO PACLITAXEL, 6MG/ML, INJECTABLE. Common uses. This medication is typically used as part of chemotherapy or for the treatment ...
  https://www.groupeproxim.ca/en/article/apo-paclitaxel
*  Feasibility Study of Intraperitoneal Paclitaxel - Full Text View - ClinicalTrials.gov
Experimental: IP Paclitaxel Paclitaxel will be administered intraperitoneally at 40mg/m2 on Days 1 and 8 in a 21-day cycle in ... Paclitaxel. Oxaliplatin. Albumin-Bound Paclitaxel. Capecitabine. Antineoplastic Agents, Phytogenic. Antineoplastic Agents. ... Feasibility Study of Intraperitoneal Paclitaxel. The safety and scientific validity of this study is the responsibility of the ... Drug: IP Paclitaxel Each treatment cycle will consist of 21 days, with 14 days on treatment and 7 days off-treatment. ...
  https://clinicaltrials.gov/ct2/show/NCT01739894
*  Cancers | Free Full-Text | Clinically Relevant Anticancer Polymer Paclitaxel Therapeutics
Furthermore, we include a short review of our recent developments of a novel poly(L-g-glutamylglutamine)-paclitaxel nano- ... This review might shed light on designing new and better polymer paclitaxel therapeutics for potential anticancer applications ... Here we focus this review on specific clinically relevant anticancer polymer paclitaxel therapeutics. We emphasize their ... Keywords: polymer paclitaxel therapeutics; polymeric micelles; polymer paclitaxel conjugates polymer paclitaxel therapeutics; ...
  http://www.mdpi.com/2072-6694/3/1/17