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*  Protective Effect of Quercetin against Oxidative Stress and Brain Edema in an Experimental Rat Model of Subarachnoid Hemorrhage
Such species include free radicals and peroxides, which cause oxidative brain injury after cerebral hemorrhage [10]. ... If not terminated fast enough, there will be damage to the cell membrane, which consists mainly of lipids. Lipid peroxidation ... Brain edema is an abnormal accumulation of fluid within the brain parenchyma, producing a volumetric enlargement of the brain ... Free Radicals and Human Disease. CRC Handbook of Free Radicals and Antioxidants. 1989;1:209-221 ...
  http://www.medsci.org/v11p0282.htm
*  Preliminary phytochemical screening and In vitro antioxidant activities of the aqueous extract of Helichrysum longifolium DC |...
The percentage inhibition of lipid peroxide at the initial stage of oxidation showed antioxidant activity of 87% compared to ... Many oxidative stress related diseases are as a result of accumulation of free radicals in the body. A lot of researches are ... Many oxidative stress related diseases are as a result of accumulation of free radicals in the body. A lot of researches are ... belongs to the Asteraceae family and consists of an estimated 600 species. The name is derived from the Greek words helisso (to ...
  https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/1472-6882-10-21
*  The Effects of Tualang Honey on Bone Metabolism of Postmenopausal Women
Hydrogen peroxide and lipid peroxidation were found to increase. These results have shown that oxidative stress was induced in ... Postmenopausal women are not only subjected to high level of free radicals and oxidative stress, but in previous studies it was ... When body is subjected to high level of oxidative stress following estrogen reduction, lipid accumulation will occur. This will ... Honey consists of primarily sugars such as monosaccharides, disaccharides, oligosaccharides, and polysaccharides [30] as well ...
  https://www.hindawi.com/journals/ecam/2012/938574/
*  Exercise in the Metabolic Syndrome
Oxidative stress impacts almost all acute and chronic progressive disorders and on a cellular basis is intimately linked to ... Oxidative Medicine and Cellular Longevity is a unique peer-reviewed, Open Access journal that publishes original research and ... review articles dealing with the cellular and molecular mechanisms of oxidative stress in the nervous system and related organ ... accompanied by lipid accumulation in skeletal muscles [149]. Increased intramyocellular lipids will increase cellular oxidative ...
  https://www.hindawi.com/journals/omcl/2012/349710/
*  Frontiers | Melatonin Improved Anthocyanin Accumulation by Regulating Gene Expressions and Resulted in High Reactive Oxygen...
We found that free radical generation was downregulated, whereas the osmotic adjustment and antioxidant capacities were ... We found that free radical generation was downregulated, whereas the osmotic adjustment and antioxidant capacities were ... This finding further proved that exogenous melatonin treatment was able to affect anthocyanin accumulation. To gain a better ... This finding further proved that exogenous melatonin treatment was able to affect anthocyanin accumulation. To gain a better ...
  https://www.frontiersin.org/articles/10.3389/fpls.2016.00197/full
*  Beta-Thalassemia Major and Female Fertility: The Role of Iron and Iron-Induced Oxidative Stress
... which catalyzes the formation of free radicals, resulting in oxidative stress (OS) and damage to mitochondria, lysosomes, lipid ... A significant increase in the levels of lipid peroxide and iron and a significant decrease in the levels of vitamin E, total ... Nonenzymic defense consists of scavenging molecules that are endogenously produced (GSH, ubiquinols, and uric acid) or derived ... Y. Asano, "Age-related accumulation of non-heme ferric and ferrous iron in mouse ovarian stroma visualized by sensitive non- ...
  https://www.hindawi.com/journals/anemia/2013/617204/
*  Glutathione - Ocala
Free radicals or oxidative stress of aging suggests that the main cause of aging comes from accumulation of free radicals and ... It prevents free radicals, heavy metals, lipid and non-lipid peroxides and other reactive oxygen species from causing damage to ... Glutathione is a tripeptide that consists of glycine, glutamine and cysteine. Glutathione, or GSH, helps to prevent damage to ... By dealing with oxidative stress and free radical formation, glutathione helps to increase muscular strength and muscle stamina ...
  https://ocalawoundcare.com/glutathione/
*  Oxidative stress and endoplasmic reticulum (ER) stress in the development of neonatal hypoxic-ischaemic brain injury |...
2006) Free radicals, mitochondria, and hypoxia-ischemia in the developing brain. Free Radic. Biol. Med. 40, 388-397 doi:10.1016 ... The immature brain has a high oxygen consumption and consists of a high concentration of free iron, water content and easily ... This could be due to the accumulation of H2O2 being exposed to high levels of free iron in the immature brain moving the Fenton ... leading to generation of hydroxyl radicals (·OH−); subsequent ·OH−-mediated cellular impairment occurs through lipid ...
  http://www.biochemsoctrans.org/content/early/2017/09/20/BST20170017
*  Oxidative stability of blesbok, springbok and fallow deer droëwors with added rooibos extract
... free lipid radicals resulting in increased lipid oxidation.28 Lipid oxidation however may also initiate protein oxidation.29 A ... At slaughter, reducing enzymes in meat are depleted, resulting in the accumulation of metmyoglobin. Metmyoglobin consists of ... 38 Lipid oxidation products include superoxide anions and hydrogen atoms which react to form hydrogen peroxide (H2O2). H2O2 ... as the products will react with the free lipid radicals resulting in increased lipid peroxidation. Of importance are the ...
  http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0038-23532015000600014&lng=en&nrm=iso&tlng=en
*  IJMS | Free Full-Text | Oxidative Stress in Malaria | HTML
In this paper we review oxidative stress mechanisms involved in the disease and discuss the potential benefits of antioxidant ... responsible for an additional production of free radicals [39].. Indeed, increased lipid peroxidation and oxidative stress ... 64], on other ROS/RNS such as the superoxide radical and hydrogen peroxide. Similarly, increased levels of iNOS in human ... promoting accumulation of free heme. Thus, chloroquine increases the availability of intracellular heme by disrupting the ...
  http://www.mdpi.com/1422-0067/13/12/16346/htm
*  Metabolites | Free Full-Text | Multiple Roles of Photosynthetic and Sunscreen Pigments in Cyanobacteria Focusing on the...
... but also their antioxidative properties may be necessary for the protection of biological molecules against the oxidative ... Reactive oxygen species (ROS), such as superoxide anion radical (O2−•), hydrogen peroxide (H2O2), and hydroxyl radical (OH•), ... Lutein and zeaxanthin have extremely low IC50 values (50% inhibitory concentration) against O2−•, OH•, and lipid peroxide ... Many MAAs consists of an aminocyclohexene imine structure as a common chromophore. It is believed that the nitrogen atom at the ...
  http://www.mdpi.com/2218-1989/3/2/463/htm
*  Redox Control of Antioxidant and Antihepatotoxic Activities of Cassia surattensis Seed Extract against Paracetamol Intoxication...
Oxidative stress impacts almost all acute and chronic progressive disorders and on a cellular basis is intimately linked to ... Oxidative Medicine and Cellular Longevity is a unique peer-reviewed, Open Access journal that publishes original research and ... review articles dealing with the cellular and molecular mechanisms of oxidative stress in the nervous system and related organ ... Electrons or hydrogen atoms might react with free radicals to stabilize or transform the free radicals into more stable and ...
  https://www.hindawi.com/journals/omcl/2016/6841348/
*  GPX4 - Wikipedia
Inactivation of GPX4 leads to an accumulation of lipid peroxides, resulting in ferroptotic cell death. Mutations in GPX4 cause ... Muller FL, Lustgarten MS, Jang Y, Richardson A, Van Remmen H (2007). "Trends in oxidative aging theories". Free Radic. Biol. ... Free Radical Biology and Medicine. 75: 95-104. doi:10.1016/j.freeradbiomed.2014.07.019. PMID 25064324. Nakagawa Y (2005). "Role ... The antioxidant enzyme glutathione peroxidase 4 (GPx4) belongs to the family of glutathione peroxidases, which consists of 8 ...
  https://en.wikipedia.org/wiki/GPX4
*  Interrelation of Oxidative Stress and Inflammation in Neurodegenerative Disease: Role of TNF
Oxidative stress impacts almost all acute and chronic progressive disorders and on a cellular basis is intimately linked to ... Oxidative Medicine and Cellular Longevity is a unique peer-reviewed, Open Access journal that publishes original research and ... review articles dealing with the cellular and molecular mechanisms of oxidative stress in the nervous system and related organ ... T. J. Montine, M. D. Neely, J. F. Quinn et al., "Lipid peroxidation in aging brain and Alzheimer's disease," Free Radical ...
  https://www.hindawi.com/journals/omcl/2015/610813/
*  Modulation of Hypercholesterolemia-Induced Oxidative/Nitrative Stress in the Heart
Oxidative stress impacts almost all acute and chronic progressive disorders and on a cellular basis is intimately linked to ... Oxidative Medicine and Cellular Longevity is a unique peer-reviewed, Open Access journal that publishes original research and ... review articles dealing with the cellular and molecular mechanisms of oxidative stress in the nervous system and related organ ... The other major free radical which contributes to oxidative/nitrative stress is NO. NO is responsible for the relaxation of ...
  https://www.hindawi.com/journals/omcl/2016/3863726/
*  Simulating Sleep Apnea by Exposure to Intermittent Hypoxia Induces Inflammation in the Lung and Liver
Oxidative stress occurs through xanthine oxidase by producing the superoxide anion radical (. ) and hydrogen peroxide [42, 43 ... B. Nath, I. Levin, T. Csak et al., "Hepatocyte-specific hypoxia-inducible factor-1α is a determinant of lipid accumulation and ... xanthine oxidase generates free radicals in the presence of oxygen, contributing to oxidative stress [6-8]. ... 2.1.2. Assessment of Lipid Peroxidation. The TBARS technique consists of heating the homogenate with thiobarbituric acid to ...
  https://www.hindawi.com/journals/mi/2012/879419/
*  Thymoquinone attenuates cisplatin-induced hepatotoxicity via nuclear factor kappa- β | BMC Complementary and Alternative...
Formation of free radicals and induction of oxidative stress is a direct cause of lipid peroxidation. Lipid peroxidation was ... such as hydroxyl radicals, superoxide anions, and hydrogen peroxide are normally generated in liver. A detoxification mechanism ... The accumulation of intracellular ROS leads to an increase in both DNA damage and peroxidation of membrane lipids [4]. ... Rats were randomly divided into three groups each consists of 15 rats. Group 1 served as the normal control group. Animals of ...
  https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/1472-6882-14-282
*  Reactive oxygen species - Wikipedia
According to the Free-radical theory, oxidative damage initiated by reactive oxygen species is a major contributor to the ... turning that molecule into a free radical and thus propagating a chain reaction. However, hydrogen peroxide is actually more ... which is accompanied by an accumulation of oxidative damage. Current studies demonstrate that the accumulation of ROS can ... lipid peroxidation) oxidations of amino acids in proteins oxidative deactivation of specific enzymes by oxidation of co-factors ...
  https://en.wikipedia.org/wiki/Reactive_oxygen_species
*  aminoisovaleric acid-alpha: Topics by WorldWideScience.org
... and also scavenged radicals (IC(50) 12.8 +/- 2.5 to 437 +/- 3.5 mg/L) and inhibited lipid peroxide formation (IC(50) 51.2 +/- ... additives and spices for their anti-oxidant ability to counteract oxidative damage due to chronic exposure to free radicals ... lipid metabolism' (4.57%. A majority of the candidate genes involved in lipid biosynthesis and oil accumulation were identified ... The family consists of one acidic ({alpha}-syntrophin, analogous to mouse syntrophin-1) and two basic ({beta}{sub 1}-syntrophin ...
  https://worldwidescience.org/topicpages/a/aminoisovaleric+acid-alpha.html
*  Tocotrienol-Rich Fraction Prevents Cell Cycle Arrest and Elongates Telomere Length in Senescent Human Diploid Fibroblasts
... the most potent lipid peroxyl radical scavenger, significantly reduced free radical-induced chromosomal damage [15]. Vitamin E ... Besides oxidative DNA damage accumulation, telomere shortening has been widely considered as another important mechanism to ... hydrogen peroxide, hydroxyl radicals, and singlet oxygen are constantly generated in most cells. High level of ROS can cause ... This effect is possibly due to the antioxidant property of TRF which consists of α-tocopherols and all isomers of tocotrienols ...
  https://www.hindawi.com/journals/bmri/2011/506171/
*  IJMS | Free Full-Text | Metabolomics as a Tool to Investigate Abiotic Stress Tolerance in Plants | HTML
Moreover, the presence/absence and relative accumulation of certain metabolites along with gene expression data provides ... lipid peroxides and DNA fragments resulting from oxidative or enzymatic cleavage. Considering the metabolome, the balance ... Polyols are also implicated in stress tolerance due to its action as scavengers of hydroxyl radicals. In addition, accumulation ... A mQTL mapping consists in computing an association between genomic markers (SSR, SNPs or CNVs) and metabolic markers. However ...
  http://www.mdpi.com/1422-0067/14/3/4885/htm
*  Dysregulation of Iron Homeostasis in the CNS Contributes to Disease Progression in a Mouse Model of Amyotrophic Lateral...
1997) Iron accumulation in Alzheimer disease is a source of redox-generated free radicals. Proc Natl Acad Sci U S A 94:9866- ... 2006) Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target. Biochim Biophys Acta 1762:1051-1067. ... Total RNA was purified from cervical, thoracic, and lumbar segments of the spinal cord using the RNeasy Lipid Tissue kit ( ... Amyotrophic lateral sclerosis (ALS), characterized by degeneration of spinal motor neurons, consists of sporadic and familial ...
  http://www.jneurosci.org/content/29/3/610.long
*  Oxidative Stress and Longevity in Okinawa: An Investigation of Blood Lipid Peroxidation and Tocopherol in Okinawan Centenarians
Correlation coefficient between tocopherol and plasma lipid peroxide.. 4. Discussion. In 1956 Harman proposed the Free Radical ... Vitamin E consists of a group of eight related fat soluble tocopherols and tocotrienols, which have significant antioxidant ... For example, the literature shows that a progressive accumulation of oxidation-derived damage to cellular machinery is linked ... The Free Radical Theory of Aging mechanistically links oxidative stress to aging. Okinawa has among the world's longest-lived ...
  https://www.hindawi.com/journals/cggr/2010/380460/
*  Mechanism of Oxidative Stress in Neurodegeneration
Oxidative stress impacts almost all acute and chronic progressive disorders and on a cellular basis is intimately linked to ... Oxidative Medicine and Cellular Longevity is a unique peer-reviewed, Open Access journal that publishes original research and ... review articles dealing with the cellular and molecular mechanisms of oxidative stress in the nervous system and related organ ... Reduced GSH can nonenzymatically act directly with free radicals, notably superoxide radicals, hydroxyl radicals, nitric oxide ...
  https://www.hindawi.com/journals/omcl/2012/428010/
*  Agronomy | Free Full-Text | Arsenic Accumulation in Rice and Probable Mitigation Approaches: A Review | HTML
Arsenic is present in different oxidative states in the environment and enters in the food chain through soil and water. In the ... Different transporters have been reported in assisting the accumulation of arsenic in plant cells; for example, arsenate (AsV) ... a by-product of lipid peroxidation [109]. Arsenic induced lipid peroxidation in several arsenic hyperaccumulator plants [109, ... Further, increased levels of hydrogen peroxide (H2O2) and malondialdehyde (MDA) generated due to AsV exposure for 24 and 48 h ...
  http://mdpi.com/2073-4395/7/4/67/htm