Presynaptic Ca2+ stores contribute to odor-induced responses in Drosophila olfactory receptor neurons | Journal of Experimental...
olfactory receptor neurons. PNs. projections neurons. RNAi. RNA interference. ROI. region of interest. RyR. ryanodine receptor ... In Drosophila, olfactory receptor neurons (ORNs), with their cell bodies and dendrites located in the antennae, detect odors ... 2009). Presynaptic peptidergic modulation of olfactory receptor neurons in Drosophila. Proc. Natl. Acad. Sci. USA 106, 13070- ... In both vertebrates and invertebrates, olfactory receptor neurons (ORNs) respond to several odors. They also adapt to stimulus ...http://jeb.biologists.org/content/213/24/4163
Gene Expression Literature Summary - MGI
Neurotrophin-3 is expressed in a discrete subset of olfactory receptor neurons in the mouse. J Comp Neurol. 2003 Aug 18;463(2): ...http://www.informatics.jax.org/gxdlit/summary/ageAssay?age=17.5&assayType=In%20situ%20reporter%20
'olfactory receptor neurons' Protocols and Video...
Functional Analysis of Neurons Expressing an Identified Odorant Receptor', 'Odorant-induced Responses Recorded from Olfactory ... Receptor Neurons using the Suction Pipette Technique', 'Whole Mount Immunolabeling of Olfactory Receptor Neurons in the ... Flash Photolysis of Caged Compounds in the Cilia of Olfactory Sensory Neurons', 'Inducing Plasticity of Astrocytic Receptors by ... Elegans Head Neurons', 'Receptor Autoradiography Protocol for the Localized Visualization of Angiotensin II Receptors', 'Insect ...https://www.jove.com/keyword/olfactory+receptor+neurons
The role of the coreceptor Orco in insect olfactory transduction | SpringerLink
Each antennal olfactory receptor neuron expresses one OR with an odorant binding site together with a conserved coreceptor ... Insects sense odorants with specialized odorant receptors (ORs). ... Each antennal olfactory receptor neuron expresses one OR with ... Stengl M, Zufall F, Hatt H, Hildebrand JG (1992) Olfactory receptor neurons from antennae of developing male Manduca sexta ... Stengl M (1993) Intracellular-messenger-mediated cation channels in cultured olfactory receptor neurons. J Exp Biol 178:125-147 ...https://link.springer.com/article/10.1007/s00359-013-0837-3
Mechanism of Signal Amplification in the Olfactory Sensory Cilia | Journal of Neuroscience
Reisert J, Bauer PJ, Yau KW, Frings S (2003) The Ca-activated Cl channel and its control in rat olfactory receptor neurons. J ... Direct modulation by Ca2+-calmodulin of cyclic nucleotide-activated channel of rat olfactory receptor neurons. Nature 368: 545- ... Time course of the membrane current underlying sensory transduction in salamander olfactory receptor neurons. J Physiol (Lond) ... Calcium/calmodulin-activated phosphodiesterase expressed in olfactory receptor neurons. J Neurosci 12: 915-923. ...http://www.jneurosci.org/content/25/48/11084
Activation of the Wnt-ßCatenin Pathway in a Cell Population on the Surface of the Forebrain Is Essential for the Establishment...
A variety of signals governing early extension, guidance, and connectivity of olfactory receptor neuron (ORN) axons has been ... The olfactory placode expresses a number of ßcatenin-activating Wnt genes, and the Frizzled7 receptor transduces the 'canonical ... These data reveal a novel function for Wnt signaling in the establishment of periphery-CNS olfactory connections and highlight ... Organotypic slice cultures that recapitulate olfactory-associated Wnt-ßcatenin activation show that the ßcatenin response ...https://air.unimi.it/handle/2434/62821
Olfactory Receptor Neurons
... are the primary sensory cell in a system designed to detect and discriminate between a large and ... Neuron 8: 205-209. Shepherd GM (1994) Discrimination of molecular signals by the olfactory receptor neuron. Neuron 13: 771-790 ... Olfactory receptor neurons are the primary sensory cell in a system designed to detect and discriminate between a large and ... Olfactory Receptor Neurons. Stuart J Firestein, Columbia University, New York, New York, USA ...http://www.els.net/WileyCDA/ElsArticle/refId-a0000273.html
Olfactory receptor neuron - Wikipedia
An olfactory receptor neuron (ORN), also called an olfactory sensory neuron (OSN), is a transduction cell within the olfactory ... Each olfactory receptor cell expresses only one type of olfactory receptor (OR), but many separate olfactory receptor cells ... The olfactory receptor neuron has a fast working negative feedback response upon depolarization. When the neuron is ... Humans have about 10 million olfactory receptor neurons. In vertebrates, ORNs are bipolar neurons with dendrites facing the ...https://en.wikipedia.org/wiki/Olfactory_receptor_neuron
Retinoic Acid Receptor-Dependent Survival of Olfactory Sensory Neurons in Postnatal and Adult Mice | Journal of Neuroscience
Expression of Bcl-2 extends the survival of olfactory receptor neurons in the absence of an olfactory bulb. Brain Res Mol Brain ... we expressed a dominant-negative retinoic acid receptor selectively in olfactory sensory neurons. We show that neurons ... OMP and odorant receptor transcripts are expressed before olfactory axons form synapses with olfactory bulb neurons, and ... Retinoic Acid Receptor-Dependent Survival of Olfactory Sensory Neurons in Postnatal and Adult Mice. Maria Hägglund, Anna ...http://www.jneurosci.org/content/26/12/3281
Frontiers | Retronasal odor concentration coding in glomeruli of the rat olfactory bulb | Frontiers in Integrative Neuroscience
... and that their olfactory bulbs (OBs) can respond to retronasal odorants but differently than to orthonasal odors. To further ... and that their olfactory bulbs (OBs) can respond to retronasal odorants but differently than to orthonasal odors. To further ... The mammalian olfactory system processes odorants presented orthonasally (inhalation through the nose) and also retronasally ( ... The mammalian olfactory system processes odorants presented orthonasally (inhalation through the nose) and also retronasally ( ...https://www.frontiersin.org/articles/10.3389/fnint.2014.00081/full
Presynaptic GABA Receptors Mediate Temporal Contrast Enhancement in Drosophila Olfactory Sensory Neurons and Modulate Odor...
Presynaptic GABA Receptors Mediate Temporal Contrast Enhancement in Drosophila Olfactory Sensory Neurons and Modulate Odor- ... Presynaptic GABA Receptors Mediate Temporal Contrast Enhancement in Drosophila Olfactory Sensory Neurons and Modulate Odor- ... Presynaptic GABA Receptors Mediate Temporal Contrast Enhancement in Drosophila Olfactory Sensory Neurons and Modulate Odor- ... Presynaptic GABA Receptors Mediate Temporal Contrast Enhancement in Drosophila Olfactory Sensory Neurons and Modulate Odor- ...https://www.ncbi.nlm.nih.gov/pubmed?term=27588305
'action potentials' Protocols and Video...
Odorant-induced Responses Recorded from Olfactory Receptor Neurons using the Suction Pipette Technique', 'Implementing Dynamic ... Using Single Sensillum Recording to Detect Olfactory Neuron Responses of Bed Bugs to Semiochemicals', 'Zebrafish In Situ Spinal ... Extracellularly Identifying Motor Neurons for a Muscle Motor Pool in Aplysia californica', 'Slice Patch Clamp Technique for ... and Culturing Identified Neurons in the Leech, Hirudo medicinalis', 'An Optogenetic Approach for Assessing Formation of ...https://www.jove.com/keyword/action+potentials
Olfactory receptor neurons. Microglomeruli were counted in 400 μm2 circles placed in the medial lip (continuous outlines) and ... 1993) An identified neuron mediates the unconditioned stimulus in associative olfactory learning in honeybees. Nature 366:59-63 ... 2007) Sequential use of mushroom body neuron subsets during Drosophila odor memory processing. Neuron 53:103-115. ... where synaptic contacts between olfactory input and MB neurons are segregated into discrete units (microglomeruli) which can be ...http://www.jneurosci.org/content/30/18/6461
Odorant Receptor Expression Defines Functional Units in the Mouse Olfactory System | Journal of Neuroscience
2001) Representation of odorants by receptor neuron input to the mouse olfactory bulb. Neuron 32:723-735. ... Odorant receptors (ORs) mediate the interaction of odorous compounds with olfactory sensory neurons (OSNs) and influence the ... 1999) Functional identification and reconstitution of an odorant receptor in single olfactory neurons. Proc Natl Acad Sci USA ... 1999) Concentration tuning mediated by spare receptor capacity in olfactory sensory neurons: a theoretical study. Neural Comput ...http://www.jneurosci.org/content/22/8/3033.full
Outline of the human brain - Wikipedia
Olfactory nerve (cranial nerve 1) Smell. See also: olfactory receptor neurons Optic nerve (cranial nerve 2) Sight. See also: ... Olfactory sensory neurons project axons to the brain within the olfactory nerve, (cranial nerve #1). How olfactory information ... Sensory neuron, Sensory receptor, Proprioception, and Category:Sensory receptors), as a center for coordinating certain ... Many neurons connect to the brain on one end, with the other end connected to another neuron, with the outside (the brain) ...https://en.wikipedia.org/wiki/Outline_of_the_human_brain
Connexin Composition in Apposed Gap Junction Hemiplaques Revealed by Matched Double-Replica Freeze-Fracture Replica Immunogold...
Mature olfactory receptor neurons express connexin43. Zhang, C; Finger, TE; Restrepo, D ... glutamate receptors and aquaporin-4 in rodent olfactory mucosa, olfactory nerve and olfactory bulb ... Connexin expression in electrically coupled postnatal rat brain neurons. Venance, L; Rosov, A; Blatow, M; Burnashev, N; ... Functional expression of the new gap junction gene connexin47 transcribed in mouse brain and spinal cord neurons ...https://www.deepdyve.com/lp/springer_journal/connexin-composition-in-apposed-gap-junction-hemiplaques-revealed-by-eIld6yiuvk
Drosophila olfactory receptor neurons project to the antennal lobe, the insect analog of the mammalian olfactory bulb. ... Smell begins when odor molecules interact with olfactory receptor neurons (ORNs). ORNs then project to the brain following ... Luo M, Katz LC (2001) Response correlation maps of neurons in the mammalian olfactory bulb. Neuron 32: 1165-1179. ... Transmission of olfactory information between three populations of neurons in the antennal lobe of the fly. Neuron 36: 463-474. ...http://www.jneurosci.org/content/25/40/9069
The Ciliary Neurotrophic Factor/Leukemia Inhibitory Factor/gp130 Receptor Complex Operates in the Maintenance of Mammalian...
1994) Discrimination of molecular signals by the olfactory receptor neuron. Neuron 13:771-790. ... Although it is known that these periglomerular neurons receive innervation from olfactory receptor cells and regulate the ... 1995) Mice lacking the CNTF receptor unlike mouse lack CNTF exhibit profound motor neuron deficits at birth. Cell 83:313-322. ... 2000) Importance of newly generated neurons in the adult olfactory bulb for odor discrimination. Proc Natl Acad Sci USA 97:1823 ...http://www.jneurosci.org/content/21/19/7642?ijkey=3e35ce8d5694ce74840bc9ca9a1f4a2e8e23ca52&keytype2=tf_ipsecsha
Drosophila Psidin Regulates Olfactory Neuron Number and Axon Targeting through Two Distinct Molecular Mechanisms | Journal of...
... contain olfactory receptor neurons (ORNs) located mostly in groups of two to four neurons inside chemosensory sensilla. ORNs ... We show that Psidin is required in several classes of olfactory receptor neurons (ORNs) for survival and subsequently for axon ... Psidin is required for pathfinding of a subset of olfactory receptor neurons. Adult brains were stained with anti-GFP (green) ... Each ORN expresses the general olfactory receptor named ORCO (Or83b) together with a specific odorant-binding receptor (OR) out ...http://www.jneurosci.org/content/32/46/16080
KAKEN - Research Projects | Analysis on gene expression involved in migration and differentiation of cranial neural crest cells...
Immunohistological detection of N-CAM and intermediate filament in the developing mouse olfactory receptor neuron.' Chemical ... These results together with region-specificity of retinoic acid receptor gene expression, retinoic acid is suggested to be ... To elucidate whether retinoic acid madiates chondrogenesis via its receptors, micromass culture was carried out using facial ... Publications] OsumiーYamashita,N.et al.: 'Retinoic acid treatment induces the ectopic expression of retinoic acid receptor beta ...https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-03670844/
Elementary response of olfactory receptor neurons to odorants. Bhandawat V, Reisert J, and Yau KW. Science 308: 1931-1934, 2005 ... This was corroborated by the fact that receptor mutations did not affect acetylcholine receptor cluster formations, timing of ... by the repetitive binding of a ligand to a receptor, or by many cells expressing the same receptor. Although this is the first ... For example, mice lacking the neuregulin-1 gene (nrg-1) or its receptors (erbB2 or erbB4) do not survive past the embryonic ...http://physiologyonline.physiology.org/content/20/5/287
Responses of olfactory receptor cells of spiny lobsters to binary mixtures. I. Intensity mixture interactions. - Semantic...
... a single receptor model, which assumes that the two compounds of a mixture bind to the same receptor site; a multiple receptor ... 2. Extracellular recordings of spiking activity of 98 primary olfactory receptor cells in the antennules were measured in ... which incorporates our current state of knowledge of transduction processes in olfactory receptor cells of spiny lobsters. 3. ... 5. The results suggest that mixture interactions in individual olfactory cells can result in intensity mixture interactions in ...https://www.semanticscholar.org/paper/Responses-of-olfactory-receptor-cells-of-spiny-to-Derby-Girardot/d28f8828400ee358482aa1443cc89e5936556a22
Pheromone Autodetection: Evidence and Implications
Grant A.J., Connell R.J. Responses of olfactory receptor neurons in Utetheisa ornatrix to gender-specific odors. J. Comp. ... Larsson M.C., Leal W.S., Hansson B.S. Olfactory receptor neurons detecting plant odours and male volatiles in Anomala cuprea ... Larsson M.C., Leal W.S., Hansson B.S. Olfactory receptor neurons specific to chiral sex pheromone components in male and female ... Ansebo L., Ignell R., Löfqvist J., Hansson B.S. Responses to sex pheromone and plant odours by olfactory receptor neurons ...http://pubmedcentralcanada.ca/pmcc/articles/PMC4931429/
Events | research.vtc.vt.edu
GABA Neurons in Schizophrenia: From Circuits to Cells to Molecular Regulation Nov. 25, 2012,. 9:12 a.m. ... The Lactate Receptor is Important for Brain Vascularization Oct. 25, 2016,. 8:34 a.m. ... How does the brain identify smells? Understanding the olfactory sense is difficult because animals must detect and identify a ... Dopamine Neuron Regulation and its Disruption in Schizophrenia and Depression Sept. 9, 2014,. 1:08 p.m. ...http://research.vtc.vt.edu/categories/events/
IL17RD Gene - GeneCards | I17RD Protein | I17RD Antibody
Interleukin 17 Receptor D, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human ... IL-17RD (Sef or IL-17RLM) interacts with IL-17 receptor and mediates IL-17 signaling. (PMID: 19079364) Rong Z … Chang Z (Cell ... Might have a role in the early stages of fate specification of GnRH-secreting neurons (By similarity). *I17RD_HUMAN,Q8NFM7 ... Anosmia or hyposmia is related to the absence or hypoplasia of the olfactory bulbs and tracts. Hypogonadism is due to ...http://www.genecards.org/cgi-bin/carddisp.pl?gene=IL17RD
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