Olfactory Receptor Neurons
... are the primary sensory cell in a system designed to detect and discriminate between a large and ... Neuron 8: 205-209. Shepherd GM (1994) Discrimination of molecular signals by the olfactory receptor neuron. Neuron 13: 771-790 ... Olfactory receptor neurons are the primary sensory cell in a system designed to detect and discriminate between a large and ... Olfactory Receptor Neurons. Stuart J Firestein, Columbia University, New York, New York, USA ...http://www.els.net/WileyCDA/ElsArticle/refId-a0000273.html
'olfactory receptor neurons' Protocols and Video...
Functional Analysis of Neurons Expressing an Identified Odorant Receptor', 'Odorant-induced Responses Recorded from Olfactory ... Receptor Neurons using the Suction Pipette Technique', 'Whole Mount Immunolabeling of Olfactory Receptor Neurons in the ... Flash Photolysis of Caged Compounds in the Cilia of Olfactory Sensory Neurons', 'Inducing Plasticity of Astrocytic Receptors by ... Elegans Head Neurons', 'Receptor Autoradiography Protocol for the Localized Visualization of Angiotensin II Receptors', 'Insect ...https://www.jove.com/keyword/olfactory+receptor+neurons
Presynaptic Ca2+ stores contribute to odor-induced responses in Drosophila olfactory receptor neurons | Journal of Experimental...
olfactory receptor neurons. PNs. projections neurons. RNAi. RNA interference. ROI. region of interest. RyR. ryanodine receptor ... In Drosophila, olfactory receptor neurons (ORNs), with their cell bodies and dendrites located in the antennae, detect odors ... 2009). Presynaptic peptidergic modulation of olfactory receptor neurons in Drosophila. Proc. Natl. Acad. Sci. USA 106, 13070- ... In both vertebrates and invertebrates, olfactory receptor neurons (ORNs) respond to several odors. They also adapt to stimulus ...http://jeb.biologists.org/content/213/24/4163
Olfactory receptor neuron - Wikipedia
An olfactory receptor neuron (ORN), also called an olfactory sensory neuron (OSN), is a transduction cell within the olfactory ... Each olfactory receptor cell expresses only one type of olfactory receptor (OR), but many separate olfactory receptor cells ... The olfactory receptor neuron has a fast working negative feedback response upon depolarization. When the neuron is ... Humans have about 10 million olfactory receptor neurons. In vertebrates, ORNs are bipolar neurons with dendrites facing the ...https://en.wikipedia.org/wiki/Olfactory_receptor_neuron
Retinoic Acid Receptor-Dependent Survival of Olfactory Sensory Neurons in Postnatal and Adult Mice | Journal of Neuroscience
Expression of Bcl-2 extends the survival of olfactory receptor neurons in the absence of an olfactory bulb. Brain Res Mol Brain ... we expressed a dominant-negative retinoic acid receptor selectively in olfactory sensory neurons. We show that neurons ... OMP and odorant receptor transcripts are expressed before olfactory axons form synapses with olfactory bulb neurons, and ... Retinoic Acid Receptor-Dependent Survival of Olfactory Sensory Neurons in Postnatal and Adult Mice. Maria Hägglund, Anna ...http://www.jneurosci.org/content/26/12/3281
Frontiers | Retronasal odor concentration coding in glomeruli of the rat olfactory bulb | Frontiers in Integrative Neuroscience
... and that their olfactory bulbs (OBs) can respond to retronasal odorants but differently than to orthonasal odors. To further ... and that their olfactory bulbs (OBs) can respond to retronasal odorants but differently than to orthonasal odors. To further ... The mammalian olfactory system processes odorants presented orthonasally (inhalation through the nose) and also retronasally ( ... The mammalian olfactory system processes odorants presented orthonasally (inhalation through the nose) and also retronasally ( ...https://www.frontiersin.org/articles/10.3389/fnint.2014.00081/full
Expression of a GABAB - Receptor in Olfactory Sensory Neurons of Sensilla trichodea on the Male Antenna of the Moth Heliothis...
Expression of a GABAB - Receptor in Olfactory Sensory Neurons of Sensilla trichodea on the Male Antenna of the Moth Heliothis ... Pregitzer P, Schultze A, Raming K, Breer H, Krieger J. Expression of a GABAB - Receptor in Olfactory Sensory Neurons of ... a GABAB receptor mediated presynaptic gain control mechanism at the first synapse between olfactory sensory neurons (OSNs) and ... Together, the results indicate that a GABAB receptor is expressed in pheromone-responsive OSNs of H. virescens and suggest a ...http://www.ijbs.com/v09p0707
Specific Mesenchymal/Epithelial Induction of Olfactory Receptor, Vomeronasal, and Gonadotropin-Releasing Hormone (GnRH) Neurons
... induction generates olfactory receptor neurons (ORNs), vomeronasal neurons (VRNs), and gonadotropin-releasing hormone (GnRH) ... neurons, the major neuron classes associated with the olfactory epithelium (OE). To assess specificity of M/E-mediated ... Moreover, only appropriate pairing of frontonasal epithelial and mesenchymal partners yields ORNs, VRNs, and GnRH neurons. ... subsequent inductive interactions specify the genesis and differentiation of peripheral chemosensory and neuroendocrine neurons ...https://dash.harvard.edu/handle/1/9888894
Presynaptic GABA Receptors Mediate Temporal Contrast Enhancement in Drosophila Olfactory Sensory Neurons and Modulate Odor...
Presynaptic GABA Receptors Mediate Temporal Contrast Enhancement in Drosophila Olfactory Sensory Neurons and Modulate Odor- ... Presynaptic GABA Receptors Mediate Temporal Contrast Enhancement in Drosophila Olfactory Sensory Neurons and Modulate Odor- ... Presynaptic GABA Receptors Mediate Temporal Contrast Enhancement in Drosophila Olfactory Sensory Neurons and Modulate Odor- ... Presynaptic GABA Receptors Mediate Temporal Contrast Enhancement in Drosophila Olfactory Sensory Neurons and Modulate Odor- ...https://www.ncbi.nlm.nih.gov/pubmed?term=27588305
'action potentials' Protocols and Video...
Odorant-induced Responses Recorded from Olfactory Receptor Neurons using the Suction Pipette Technique', 'Implementing Dynamic ... Using Single Sensillum Recording to Detect Olfactory Neuron Responses of Bed Bugs to Semiochemicals', 'Zebrafish In Situ Spinal ... Extracellularly Identifying Motor Neurons for a Muscle Motor Pool in Aplysia californica', 'Slice Patch Clamp Technique for ... and Culturing Identified Neurons in the Leech, Hirudo medicinalis', 'An Optogenetic Approach for Assessing Formation of ...https://www.jove.com/keyword/action+potentials
Dopamine Systems in the Forebrain | SpringerLink
Olfactory receptor neurons express D2 dopamine receptors. J Comp Neurol 1999; 411(4):666-673.PubMedCrossRefGoogle Scholar ... Tyrosine Hydroxylase Olfactory Bulb Neural Stem Cell Subventricular Zone Olfactory Receptor Neuron These keywords were added by ... Olfactory deprivation increases dopamine D2 receptor density in the rat olfactory bulb. Synapse 1991; 8:61-70.PubMedCrossRef ... Dopamine receptor subtypes modulate olfactory bulb gamma-aminobutyric acid type A receptors. Proc Natl Acad Sci USA 1999; 96(5 ...https://link.springer.com/chapter/10.1007/978-1-4419-0322-8_2
Frontiers | Functional and evolutionary aspects of chemoreceptors | Frontiers in Cellular Neuroscience
This perspective discusses the physical limits of chemoreception and gives an overview on the receptor types developed during ... This perspective discusses the physical limits of chemoreception and gives an overview on the receptor types developed during ... In mammalian olfactory sensory neurons, odor binding activates the olfactory receptor (OR), a GPCR bound to a stimulatory Golf ... Ben-Chaim, Y., Cheng, M. M., and Yau, K. W. (2011). Unitary response of mouse olfactory receptor neurons. Proc. Natl. Acad. Sci ...https://www.frontiersin.org/articles/10.3389/fncel.2012.00048/full
Linking neuronal lineage and wiring specificity | Springer for Research & Development
Drosophila olfactory receptor neurons. Olfactory receptor neurons (ORNs) are the primary sensory neurons of the Drosophila ... Drosophila olfactory projection neurons. In the Drosophila olfactory system, 50 classes of olfactory receptor neurons (ORNs) ... GABAergic projection neurons route selective olfactory inputs to specific higher-order neurons. Neuron. 2013;79:917-31. https ... including Drosophila olfactory projection neurons (PNs), mushroom body (MB) neurons and mouse cortical excitatory neurons. In ...https://rd.springer.com/article/10.1186/s13064-018-0102-0
Olfactory receptor neurons. Microglomeruli were counted in 400 μm2 circles placed in the medial lip (continuous outlines) and ... 1993) An identified neuron mediates the unconditioned stimulus in associative olfactory learning in honeybees. Nature 366:59-63 ... 2007) Sequential use of mushroom body neuron subsets during Drosophila odor memory processing. Neuron 53:103-115. ... where synaptic contacts between olfactory input and MB neurons are segregated into discrete units (microglomeruli) which can be ...http://www.jneurosci.org/content/30/18/6461
Odorant Receptor Expression Defines Functional Units in the Mouse Olfactory System | Journal of Neuroscience
2001) Representation of odorants by receptor neuron input to the mouse olfactory bulb. Neuron 32:723-735. ... Odorant receptors (ORs) mediate the interaction of odorous compounds with olfactory sensory neurons (OSNs) and influence the ... 1999) Functional identification and reconstitution of an odorant receptor in single olfactory neurons. Proc Natl Acad Sci USA ... 1999) Concentration tuning mediated by spare receptor capacity in olfactory sensory neurons: a theoretical study. Neural Comput ...http://www.jneurosci.org/content/22/8/3033.full
Outline of the human brain - Wikipedia
Olfactory nerve (cranial nerve 1) Smell. See also: olfactory receptor neurons Optic nerve (cranial nerve 2) Sight. See also: ... Olfactory sensory neurons project axons to the brain within the olfactory nerve, (cranial nerve #1). How olfactory information ... Sensory neuron, Sensory receptor, Proprioception, and Category:Sensory receptors), as a center for coordinating certain ... Many neurons connect to the brain on one end, with the other end connected to another neuron, with the outside (the brain) ...https://en.wikipedia.org/wiki/Outline_of_the_human_brain
Frontiers | Tachykinin Expression Levels Correlate with Caste-Specific Aggression in Workers of the Leaf-Cutting Ant Acromyrmex...
... in combination with behavioral assays to test for associations between the expression of Tachykinin and its receptor, and the ... in combination with behavioral assays to test for associations between the expression of Tachykinin and its receptor, and the ... Expression of tachykinin in a cluster of neurons was recently shown to determine the stimulus response threshold for aggressive ... Expression of tachykinin in a cluster of neurons was recently shown to determine the stimulus response threshold for aggressive ...https://www.frontiersin.org/articles/10.3389/fevo.2016.00055/full
Connexin Composition in Apposed Gap Junction Hemiplaques Revealed by Matched Double-Replica Freeze-Fracture Replica Immunogold...
Mature olfactory receptor neurons express connexin43. Zhang, C; Finger, TE; Restrepo, D ... glutamate receptors and aquaporin-4 in rodent olfactory mucosa, olfactory nerve and olfactory bulb ... Connexin expression in electrically coupled postnatal rat brain neurons. Venance, L; Rosov, A; Blatow, M; Burnashev, N; ... Functional expression of the new gap junction gene connexin47 transcribed in mouse brain and spinal cord neurons ...https://www.deepdyve.com/lp/springer_journal/connexin-composition-in-apposed-gap-junction-hemiplaques-revealed-by-eIld6yiuvk
Drosophila olfactory receptor neurons project to the antennal lobe, the insect analog of the mammalian olfactory bulb. ... Smell begins when odor molecules interact with olfactory receptor neurons (ORNs). ORNs then project to the brain following ... Luo M, Katz LC (2001) Response correlation maps of neurons in the mammalian olfactory bulb. Neuron 32: 1165-1179. ... Transmission of olfactory information between three populations of neurons in the antennal lobe of the fly. Neuron 36: 463-474. ...http://www.jneurosci.org/content/25/40/9069
2002) 3-Phosphoinositides modulate cyclic nucleotide signaling in olfactory receptor neurons. Neuron 33:731-739. ... 2008) A behavioral switch: cGMP and PKC signaling in olfactory neurons reverses odor preference in C. elegans. Neuron 59:959- ... has been shown to modulate the excitability of rodent olfactory receptor neurons (Spehr et al., 2002). The finding that daf-18 ... in ASER neurons using the gcy-5 promoter, in AWB neurons using str-1 promoter, or in ASH and ASI neurons using promoter sra-6 ...http://www.jneurosci.org/content/30/23/8001
Frontiers | Tuning Insect Odorant Receptors | Frontiers in Cellular Neuroscience
A special property of this receptor type is the capability to adjust sensitivity of odor detection according to previous odor ... A special property of this receptor type is the capability to adjust sensitivity of odor detection according to previous odor ... Among the insect olfactory receptors the odorant receptors (ORs) evolved in parallel to the onset of insect flight. ... Among the insect olfactory receptors the odorant receptors (ORs) evolved in parallel to the onset of insect flight. ...https://www.frontiersin.org/articles/10.3389/fncel.2018.00094/full?utm_source=F-NTF&utm_medium=EMLX&utm_campaign=PRD_FEOPS_20170000_ARTICLE
The Ciliary Neurotrophic Factor/Leukemia Inhibitory Factor/gp130 Receptor Complex Operates in the Maintenance of Mammalian...
1994) Discrimination of molecular signals by the olfactory receptor neuron. Neuron 13:771-790. ... Although it is known that these periglomerular neurons receive innervation from olfactory receptor cells and regulate the ... 1995) Mice lacking the CNTF receptor unlike mouse lack CNTF exhibit profound motor neuron deficits at birth. Cell 83:313-322. ... 2000) Importance of newly generated neurons in the adult olfactory bulb for odor discrimination. Proc Natl Acad Sci USA 97:1823 ...http://www.jneurosci.org/content/21/19/7642?ijkey=3e35ce8d5694ce74840bc9ca9a1f4a2e8e23ca52&keytype2=tf_ipsecsha
King-Wai Yau - The Solomon H Snyder Department of Neuroscience
... response of mouse olfactory receptor neurons. Neuron 45, 553-561.. Kefalov, V., Fu, Y., Marsh-Armstrong, N. and Yau, K.-W. ( ... Bhandawat, V., Reisert, J. and Yau, K.-W. (2005). Elementary response of olfactory receptor neurons to odorants. Science 308, ... Neuron 46, 879-890.. Dacey, D.M., Liao, H.-W., Peterson, B.B., Robinson, F.R., Smith, V.C., Pokorny, J., Yau, K.-W. and Gamlin ...http://neuroscience.jhu.edu/research/faculty/100/publications
Drosophila Psidin Regulates Olfactory Neuron Number and Axon Targeting through Two Distinct Molecular Mechanisms | Journal of...
... contain olfactory receptor neurons (ORNs) located mostly in groups of two to four neurons inside chemosensory sensilla. ORNs ... We show that Psidin is required in several classes of olfactory receptor neurons (ORNs) for survival and subsequently for axon ... Psidin is required for pathfinding of a subset of olfactory receptor neurons. Adult brains were stained with anti-GFP (green) ... Each ORN expresses the general olfactory receptor named ORCO (Or83b) together with a specific odorant-binding receptor (OR) out ...http://www.jneurosci.org/content/32/46/16080
KAKEN - Research Projects | Analysis on gene expression involved in migration and differentiation of cranial neural crest cells...
Immunohistological detection of N-CAM and intermediate filament in the developing mouse olfactory receptor neuron.' Chemical ... These results together with region-specificity of retinoic acid receptor gene expression, retinoic acid is suggested to be ... To elucidate whether retinoic acid madiates chondrogenesis via its receptors, micromass culture was carried out using facial ... Publications] OsumiーYamashita,N.et al.: 'Retinoic acid treatment induces the ectopic expression of retinoic acid receptor beta ...https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-03670844/