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Neuroregulation of nonexercise activity thermogenesis and obesity resistance | Regulatory, Integrative and Comparative...
High levels of spontaneous physical activity in lean people and the nonexercise activity thermogenesis (NEAT) derived from that activity appear to protect lean people from obesity during caloric challenge, while obesity in humans is characterized by dramatically reduced spontaneous physical activity. We have similarly demonstrated that obesity-resistant rats have significantly greater spontaneous physical activity than obesity-prone rats, and that spontaneous physical activity predicts body weight gain. Although the energetic cost of activity varies between types of activity and may be regulated, individual level of spontaneous physical activity is important in determining propensity for obesity. We review the current status of knowledge about the brain mechanisms involved in controlling the level of spontaneous physical activity and the NEAT so generated. Focus is on potential neural mediators of spontaneous physical ...http://ajpregu.physiology.org/content/294/3/R699.short
Visfatin in overweight/obesity, type 2 diabetes mellitus, insulin resistance, metabolic syndrome and cardiovascular diseases: a...
There are controversies regarding the association of visfatin with overweight/obesity, type 2 diabetes mellitus, insulin resistance (IR), metabolic syndrome and cardiovascular disease in published articles. A meta-analysis was performed to identify the significance of visfatin in these diseases. We searched for relevant articles in Pubmed, Scopus and SCIE. A total of 1035 articles were surveyed and 46 articles were identified, with 14 reports reporting more than one of our investigated diseases. A total of 13 (n = 644), 19 (n = 2405), 20 (n = 2249), 5 (n = 527) and 5 (n = 851) articles/(participants) were included in each meta-analysis regarding the association of visfatin and overweight/obesity, type 2 diabetes mellitus, insulin resistance, metabolic syndrome and cardiovascular diseases, respectively. Plasma visfatin concentrations were increased in participants diagnosed with overweight/obesity, type 2 diabetes mellitus, metabolic syndrome and ...http://onlinelibrary.wiley.com/doi/10.1002/dmrr.1201/full?globalMessage=0&systemMessage=Wiley+Online+Library+will+be+unavailable+on+Saturday+7th+Oct+from+03.00+EDT+%2F+08%3A00+BST+%2F+12%3A30+IST+%2F+15.00+SGT+to+08.00+EDT+%2F+13.00+BST+%2F+17%3A30+IST+%2F+20.00+SGT+and+Sunday+8th+Oct+from+03.00+EDT+%2F+08%3A00+BST+%2F+12%3A30+IST+%2F+15.00+SGT+to+06.00+EDT+%2F+11.00+BST+%2F+15%3A30+IST+%2F+18.00+SGT+for+essential+maintenance.+Apologies+for+the+inconvenience+caused+
The Risks of Very Low Calorie Diets
Very Low Calorie Diets (VLCDs) are popular because of the fast weight loss that can result. However, they aren't always what they're cracked up to be.https://www.diet-blog.com/08/the_risks_of_very_low_calorie_diets.php?replytocom=26980
Healthy Bodies, Healthy Kids - Full Text View - ClinicalTrials.gov
This project will utilize sensitive, early biomarkers of disease risk, including whole body adiposity with DEXA, HTGC and CIMT, directly relevant to diabetes and cardiovascular disease risk. The primary goals of this study are to deliver an evidence-based weight loss intervention to the population of youth who are overweight or obese as a result of antipsychotic treatment, to characterize metabolic risk associated with weight using sensitive biomarkers, and to evaluate the magnitude of change observed in these biomarkers in children receiving an established behavioral weight-loss intervention. This study will completed in two phases.. Study Phase 1, Aim 1: To test the feasibility of delivering an existing family-based behavioral weight loss program in families of psychiatrically ill youth who are overweight or obese.. Study Phase 2, Aim 1: To evaluate the effect of 16 weeks of the behavioral weight loss intervention on DEXA-measured whole body adiposity in overweight/obese antipsychotic-treated ...https://clinicaltrials.gov/ct2/show/NCT01222494?term=Carotid+Artery+Disease&recr=Open&fund=01&rank=10
Determinants of left ventricular mass in obesity; a cardiovascular magnetic resonance study. - Physiology, Anatomy and Genetics
BACKGROUND: Obesity is linked to increased left ventricular mass, an independent predictor of mortality. As a result of this, understanding the determinants of left ventricular mass in the setting of obesity has both therapeutic and prognostic implications. Using cardiovascular magnetic resonance our goal was to elucidate the main predictors of left ventricular mass in severely obese subjects free of additional cardiovascular risk factors. METHODS: 38 obese (BMI 37.8 +/- 6.9 kg/m2) and 16 normal weight controls subjects, (BMI 21.7 +/- 1.8 kg/m2), all without cardiovascular risk factors, underwent cardiovascular magnetic resonance imaging to assess left ventricular mass, left ventricular volumes and visceral fat mass. Left ventricular mass was then compared to serum and anthropometric markers of obesity linked to left ventricular mass, i.e. height, age, blood pressure, total fat mass, visceral fat mass, lean mass, serum leptin and fasting insulin level. ...https://www.dpag.ox.ac.uk/publications/105037
Effect of Diet-induced Weight Loss on HIV-associated Metabolic Syndrome - Full Text View - ClinicalTrials.gov
Obese HIV-positive women with Metabolic Syndrome (HIV-MS) and obese HIV-negative women with Metabolic Syndrome will be studied before and after achieving moderate (6%-8%) diet-induced weight loss. The investigators hypothesize that health markers will improve in both groups but that the improvement will be blunted in the women with HIV-MS ...https://clinicaltrials.gov/show/NCT00857298?order=47
A Trial to Investigate the Impact of a Low Glycemic Index (GI) Diet on Body Mass Index and Obesity Related Cardiovascular and...
Epidemiological studies suggest a role for a low glycemic index (GI) diet in the management of obesity and associated metabolic risks including diabetes. However, evidence from long-term, randomized controlled trials exploring the relationship between low GI diet, weight reduction and glycemia, particularly in children and adolescents, is lacking. Modern food-processing technology has produced many food products with high GI which may contribute to the burgeoning epidemic of obesity worldwide. Since dietary habits are shaped in early life, adolescence is a critical period to educate our young people to acquire a healthy eating habit to prevent obesity.. The investigators hypothesized that, in Chinese adolescents, low GI diet results in greater reduction in body mass index and body fat percentage, enhanced insulin sensitivity and favorable changes of cardiometabolic risk factors compared to conventional diet after 12 months of intervention.. This study is a ...https://clinicaltrials.gov/ct2/show/NCT01278563?recr=Open&cond=%22Body+Mass+Index%22&rank=8
Weight Loss Programs Anchorage AK - body fat, Anchorage AK lean body mass, Anchorage AK metabolism, Anchorage AK strength...
This page provides useful content and local businesses that can help with your search for Weight Loss Programs. You will find helpful, informative articles about Weight Loss Programs, including The Secret Weapon of Weight Loss and Physical Health, Weight Loss: Which Tools are Best?, and Why Losing Weight is so Hard and Gaining Weight is so Easy. You will also find local businesses that provide the products or services that you are looking for. Please scroll down to find the local resources in Anchorage, AK that will answer all of your questions about Weight Loss Programs.http://local.sheerbalance.com/Weight_Loss_Programs_Anchorage_AK-p1585957-Anchorage_AK.html
Insights into the Genetic Susceptibility to Type 2 Diabetes from Genome-Wide Association Studies of Obesity-Related Traits. -...
Obesity and type 2 diabetes (T2D) are common and complex metabolic diseases, which are caused by an interchange between environmental and genetic factors. Recently, a number of large-scale genome-wide association studies (GWAS) have improved our knowledge of the genetic architecture and biological mechanisms of these diseases. Currently, more than ~250 genetic loci have been found for monogenic, syndromic, or common forms of T2D and/or obesity-related traits. In this review, we discuss the implications of these GWAS for obesity and T2D, and investigate the overlap of loci for obesity-related traits and T2D, highlighting potential mechanisms that affect T2D susceptibility.https://www.bdi.ox.ac.uk/publications/567786
Red Hot Chili Peppers Rock Obesity Research | Science Translational Medicine
Brown fat, a heat-producing organ in human infants and hibernating mammals, was shown recently to be present in human adults and to participate in energy expenditure. Although brown fat seems to be a logical target for obesity treatments that enhance the organ's ability to burn energy, disappointing studies show that most obese people display undetectable levels of brown-fat metabolism. Now, a study by Yoneshiro et al. shows that hope remains in the quest to target brown fat for weight loss.. The authors treated participants who displayed low or undetectable brown-fat metabolism (as assessed by fluorodeoxyglucose positron emission tomography) with 6 weeks of daily exposure to cold (17°C for 2 hours), which resulted in significant activation of brown fat-and thus energy expenditure-in 50% of the study participants. These individuals lost an average of 5.2% of their body fat mass over a 6-week period after cold treatment. Cold exposure is known to be a powerful physiological stimulus for ...http://stm.sciencemag.org/content/5/195/195ec123
Virus Induced Obesity - what the hell!?, page 1
A virally induced obesity syndrome in mice. Lyons MJ, Faust IM, Hemmes RB, Buskirk DR, Hirsch J, Zabriskie JB. An obesity syndrome was found in a number of mice infected as young adults with canine distemper virus, a morbillivirus antigenically related to measles. Body weights of obese animals 16 to 20 weeks after infection were comparable to those reported for genetically obese mice and for mice rendered obese by hypothalamic lesions. The total number of adipocytes in specific fat deposits was greater in obese animals than in their lean littermates. This hyperplasia was accompanied by moderate cell enlargement. Pancreatic islet tissue was also hypercellular in the obese mice. Brain tissue from the obese mice showed no overt pathology, and immunofluorescence staining for viral antigens was negative. There may be a selective, virus-induced disruption of critical brain catecholamine pathways ...http://www.abovetopsecret.com/forum/thread189873/pg1
Vol. 28 No. 3 - Overweight and Obesity: An Update | National Lymphedema Network
By Catherine M. Tuppo, PT, MS, CLT-LANA, Stony Brook Medicine Department of Surgery, Bariatric and Metabolic Weight Loss Center, Stony Brook, NY. Vol. 28 No. 3 - Lymphlink Reprint, Archived July 2015. Click here to download a pdf version. Introduction Obesity was recognized as a disease by the American Medical Association in 2013. More than two thirds (68.5%) of adults in the US are considered to be overweight or obese, with 34.9% being obese. 1, 2, 3 Worldwide by 2030, 60% of the population will be considered overweight or obese. 4 Approximately $147 billion are expended annually in the US for the treatment of medical conditions related to obesity, with individual medical costs being 42% higher for an individual with obesity than for others. 5. What do overweight and obesity mean?. Obesity is a disease categorized by excess body fat. Various measures are utilized for assessment, including body weight, body mass index (BMI), ...https://www.lymphnet.org/resources/vol-28-no-3-overweight-and-obesity-an-update
British Library EThOS: An investigation of health care professionals' attitudes to obesity and the associated impact on...
Background: The obesity pandemic is causing premature mortality, increasing morbidity and escalating healthcare costs. It is globally acknowledged that current obesity management strategies are failing. It is also accepted that clinicians may hold an Anti-fat bias. To-date it has not been established if there is a relationship between strategy failures and clinicians' attitudes. This 'uncharted territory' was the driving impetus to undertaken a study investigating possible links and consequences. Aims: To establish healthcare clinicians' attitudes towards patients with obesity and test the extent to which their attitudes influenced obesity management. Methods: Online vignettes were generated via Factorial Survey Design methods to assess obesity management by clinicians. The obesity Implicit Association Test (IAT) was used to assess subconscious Anti-fat bias. Data were collected anonymously from a ...http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.695318
Sleep Restriction and Obesity - Full Text View - ClinicalTrials.gov
Numerous studies have reported that self-reported short sleep duration is associated with obesity and weight gain. Insufficient sleep may be one of the most common, and most preventable, obesity risk factors. Given that sleep restriction is largely voluntary and potentially correctable, understanding the mechanisms that link insufficient sleep to positive energy balance and the development of obesity, particularly visceral obesity, is crucial to clinical applications, public health policy, and informing future studies. The investigators wish to determine whether 14 nights of modest sleep restriction results in increased energy balance, thus potentially increasing the risk of obesity. The investigators will combine energy balance, biomarker, and imaging data with state-of-the art sleep monitoring to provide unambiguous data on the effects of sleep restriction on obesity. Together, the investigators findings ...https://clinicaltrials.gov/show/NCT01580761
Nutritional status and risk factors of overweight and obesity for children aged 9-15 years in Chengdu, Southwest China | BMC...
Obesity and overweight has become worldwide epidemic not only in adults but also in children. Given that area differences in nutritional status could not be excluded, we surveyed the nutritional status of school children aged 9-15 yrs in Chengdu, which is one of the latest cities in Southwest China. Approximately 17.8% of school children were in excess body weight, of which 14.5% were overweight and 3.3% were obesity. The combined prevalence was twice higher than that reported in the retrospective evaluation of nutritional status in children from the 2002 China National Nutrition and Health Survey (CNNHS), which applied the same reference of WHO (2007) . Whereas it was still lower than the percentage of 25.7% among 10-15 yrs children in Beijing also with the same reference . The prevalence of obesity in this study was a little lower than that reported among children aged 10-15 yrs in Xi`an, which was also a relatively backward city in West China ...https://bmcpublichealth.biomedcentral.com/articles/10.1186/1471-2458-12-636
Although average Body Mass Index (BMI) numbers have been holding somewhat steady in recent years, American waistlines continue to expand, which is bad news for our country's health. The latest look at these measurements focuses on the changes over time in abdominal obesity. This "belly fat" is closely associated with metabolic syndrome, and can indicate increased risks of diabetes and heart disease. The investigation reveals that since 1999, waistlines and belly fat have increased among men, women, whites, blacks and Mexican Americans. The researchers, from the U.S. Centers for Disease Control and Prevention (CDC), reported that in 2012 abdominal obesity was present in 54.2 percent of us, up from 46.4 percent in 1999. (In men, a waist measurement greater than 40.2 inches signals abdominal obesity. For women, abdominal obesity is present at a waist measurement greater than 34.6 inches). The CDC team analyzed data from nearly 33,000 men and ...http://ifmofsa.com/category/abdominal-obesity/
Bmi morbid obesity chart - Answers on HealthTap
Doctor answers on Symptoms, Diagnosis, Treatment, and More: Dr. Liu on bmi morbid obesity chart: Once obesity has become this extreme, successful weight loss by diet alone is unlikely. She would do well to ask her physician about bariatric surgery. for topic: Bmi Morbid Obesity Charthttps://www.healthtap.com/topics/bmi-morbid-obesity-chart
Leptin resistance: a prediposing factor for diet-induced obesity | Regulatory, Integrative and Comparative Physiology
This review examined several models of leptin resistance and the role of leptin resistance in the susceptibility to dietary obesity. Only some of the leptin-resistance models (leptin antagonist blockade and aged obese rats) exhibit heightened weight and adiposity gain on a chow diet, while all models discussed demonstrate obesity in the presence of an HF diet. Thus, the leptin resistance appears to be reinforcing "reward eating" beyond caloric energy requirements. Overconsumption of palatable food could be mediated by activation of reward circuitry involving opioids and dopamine or an impairment in a pathway (or pathways) mediating satiation of the palatable diet (16).. Whereas the hypothalamus, in particular, the arcuate nucleus, has been identified as important in regulating the caloric requirements, other regions in the hypothalamus, such as lateral hypothalamus and extrahypothalamus areas including the amygdale, prefrontal cortex, nuclear accumbens, and ventral tegmental ...http://ajpregu.physiology.org/content/296/3/R493.long
Trends in childhood obesity and central adiposity between 1998-2001 and 2010-2012 according to household income and urbanity in...
The results of this study showed gender differences in the relationship of childhood obesity with household income and urbanity. Childhood obesity and overweight tended to be more prevalent in boys with high household income or urban residency and in girls with low household income or rural residency. Similar gender differences were also found for WC and BMI Z-score. These clear gender differences in Korea are interesting because, in recent years, positive relationships between adiposity measures and SEP have become uncommon, particularly in developed countries . A recent study conducted in Poland showed similar gender differences with respect to SEP in relation with WC and BMI . Two explanations are possible. One possible explanation is that body image perception and associated weight control behavior differ according to gender and SEP . For example, a recent Korean study has shown that weight misperception was more prevalent among girls than boys (57.9 % of ...https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-015-2616-2
The Campaign Against Childhood Obesity - Massachusetts General Hospital, Boston, MA
Some people have a natural tendency to gain weight easily, because of genetic or other biological characteristics. In a family where one or both parents have obesity, the children are also more likely to be "easy gainers" and develop a weight problem as they grow, even if they are thin or average weight during early childhood. These families should be particularly careful to live a healthy lifestyle and to teach their children healthy habits, to help the child maintain a healthy body weight as he or she grows up.. Q: Do you think Michelle Obama's obesity campaign is a step in the right direction?. A: Absolutely! Supported by Mrs. Obama's high profile and wide respect, the campaign puts a national focus on obesity, and brings attention to the issue to people outside the medical field. The campaign prompts parents and children to sit around the dinner table and talk about the importance of this issue, and to think about changes they can make in their own ...http://www.massgeneral.org/children/about/newsarticle.aspx?id=2938
HCG Dieting, Bariatric Surgery and the Treatment of Morbid Obesity
Trying to decide between surgical intervention or aggressive dieting? For people who are morbidly obese, losing weight fast is a priority. It can be a matter not just of desire, but shedding pounds is also important to a person's health both now and in the future.. Many overweight individuals have found success with the homeopathic HCG weight loss approach. For those with lots to lose, more than one course of treatment on the diet can be utilized. People take time off in between the diet phases, during which they work on maintaining their successful weight loss. This is called the maintenance phase. The use of HCG dieting support tools like the trusty food scale and body weight scale is important.. Another approach to achieve desired results is to undergo bariatric surgery. This is a surgical procedure where your stomach undergoes resection to promote rapid weight loss. However, before undergoing the operation it is important that you familiarize yourself with the procedure and how it can affect ...http://www.willwellness.com/861/hcg-dieting-bariatric-surgery-and-the-treatment-of-morbid-obesity/
Abstract 16843: Waist Measures are an Important Factor Further Specifying Adiposity-Related Cardiometabolic Risk for Children...
Background: Body mass index (BMI) is commonly used as an indirect indicator of adiposity in children reflective of its association with cardiometabolic risk. The interaction of waist circumference percentile (WC%) and waist-to-height ratio (WHtR) with BMI may provide further risk specification in children.. Methods: Data were analyzed from 5 NHANES surveys from 1999-2008. Two sets of groups were created based on categories of BMI/WC% and BMI/WHtR to assess the interaction of waist measures and BMI percentile (WHO charts) in association with cardiometabolic risk factors, including fasting lipids, glucose and insulin, C-reactive protein (CRP) and blood pressure category.. Results: Data were available for 14,802 subjects (age range 5-18.9 years, 50% male, 4,542 fasting blood work). Overweight (BMI≥85%) and obesity (BMI≥95%) were noted for 13% and 27%, respectively. WC% ≥ 90% and WHtR ≥ 0.6 were noted in 16% and 10%, respectively. Both between and within BMI categories, increasing waist ...http://circ.ahajournals.org/content/124/Suppl_21/A16843
SAT0482 Overweight Prevalence in Children and Adolescents with Juvenile Idiopathic Arthritis in Dependence on Health and...
Results In 2005 a total of 3,622 patients with JIA were included in the analysis, median age was 11 years, 14.4% were overweight. Associated variables with overweight were subgroup, age, participation in school sports, medication with glucocorticoids and level of functional restriction. As influencing factors for overweight the systemic JIA, functional restrictions, and the non-participation in school sports were identified.. Weight status did not differ from controls, although slight differences in health- and lifestyle-aspects were found. Differences between patients and reference group affected duration and frequency of physical activity.. Trend analysis showed a reduction in overweight prevalence from 2003 until 2010 (-4.9%). Especially among patients with systemic JIA the overweight prevalence decreased (-9.6%). Reduction of overweight rate was accociated by an improved funtional status.. ...http://ard.bmj.com/content/72/Suppl_3/A744.3
Woman with Meal - 4 Week - Shake That Weight
Achieving a healthy weight target is all about finding the right balance between the amount of energy (kals) you consume and the amount your burn off . If you are actively trying to lose weight then eating healthy meals and maintaining physical fitness is the key to success!. Sometimes you need a bit of extra help, which is where a very low calorie diet or VLCD, can be the correct choice for you. The principal is simple, to lose weight you need to use more energy than you consume. A Very low calorie diet lowers your daily calorie intake significantly more than traditional diets.. This means more rapid weight loss than traditional diets.. VLCD plans like shake that weight are now recognised by the NHS and are openly discussed as a method of successful dieting on NHS choices.. The national institute for clinical excellence (nice) recommends that VLCD's (diets under 1000 calories) should only be followed constantly for 12 weeks and then you should take a break. This diet is also not recommended for ...https://www.shakethatweight.co.uk/shop/week-plans/woman-meal-4/
Increased adipose tissue expression of lipocalin-2 in obesity is related to inflammation and matrix metalloproteinase-2 and...
Increased adipose tissue expression of lipocalin-2 in obesity is related to inflammation and matrix metalloproteinase-2 and metalloproteinase-9 activities in humans. Increased adipose tissue expression of lipocalin-2 in obesity is related to inflammation and matrix metalloproteinase-2 and metalloproteinase-9 activities in humanshttp://www.cun.es/en/research/scientific-publications/increased-adipose-tissue-expression-lipocalin-2-obesity
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