*  British Library EThOS: Design and synthesis of peptides derived from nucleoside β-amino acids
Beginning with the natural nucleosides thymidine and 2'-deoxyadenosine, syntheses of 4 different nucleoside β -amino acid ... The structure of the β -amino acids involves conversion of the 3'-hydroxyl group of the nucleoside sugar into an amino group ( ... This project is concerned with the design and synthesis of β-peptide foldamers which are assembled from nucleoside derived β - ... that the combination of the inherent helix folding properties of peptides and the associated characteristics of nucleosides ...
  http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.569173
*  Derivatized oligonucleotides having improved uptake and other properties - Patent # 7122649 - PatentGenius
... nucleoside or on the inter-nucleotide linkage linking the nucleoside to an adjacent nucleoside. ... If at least a portion of the remaining liked nucleosides are 2'-deoxy-2'-fluoro, 2'-O-methoxy, 2'-O-ethoxy, 2'-O-propoxy, 2'-O- ... The substituent can be attached at the 2'-position of the functionalized nucleoside via a linking group. ... aminoalkoxy or 2'-O-allyloxy nucleosides, the substituent can be attached via a linking group at any of the 3' or the 5' ...
  http://www.patentgenius.com/patent/7122649.html
*  Plus it
Electrogenic uptake of nucleosides and nucleoside-derived drugs by the human nucleoside transporter 1 (hCNT1) expressed in ... Human equilibrative nucleoside transporter 1 and human concentrative nucleoside transporter 3 predict survival after adjuvant ... membrane-bound nucleoside transporters are prerequisites (as cells deficient in nucleoside transporter are resistant to ... a concentrative nucleoside transporter involved in the uptake of cell-cycle-dependent nucleoside-derived anticancer drugs. ...
  http://cancerres.aacrjournals.org/content/71/5/1825
*  "Protein Profiling of Adenine Nucleoside and Nucleotide Analogs Binding" by Shikha Mahajan
In this research, an affinity based approach for the enrichment of nucleotide and nucleoside binding proteins from a complex ... The approach was extended to compare the proteomic profiles of nucleotide and nucleoside binding proteins in cancerous (Hey) ... Upon enrichment, the photolabeled proteome exhibited an approximately four-fold abundance of nucleoside and nucleotide binding ... have been designed and synthesized to photolabel the nucleotide and nucleoside binding proteins. These probes contain a ...
  http://scholarcommons.usf.edu/etd/4139/
*  Effect of Nucleosides on Acute Left Ventricular Failure in the Isolated Dog Heart | Circulation Research
Effect of Nucleosides on Acute Left Ventricular Failure in the Isolated Dog Heart. N. M. BUCKLEY, K. K. TSUBOI, N. J. ZEIG ... The effect of nucleosides on acute left ventricular failure was studied in 15 isolated dog hearts. The unilateral failure was ... Effect of Nucleosides on Acute Left Ventricular Failure in the Isolated Dog Heart ... Effect of Nucleosides on Acute Left Ventricular Failure in the Isolated Dog Heart ...
  http://circres.ahajournals.org/content/7/6/847
*  Antiviral activity of nucleoside analogues during short-course monotherapy or dual therapy: Its role in preventing HIV...
Antiviral activity of nucleoside analogues during short-course monotherapy or dual therapy: Its role in preventing HIV ... Antiviral activity of nucleoside analogues during short-course monotherapy or dual therapy: Its role in preventing HIV ... The preliminary efficacy of four different short-course nucleoside analogue regimens, stavudine (d4T), didanosine (ddI), d4T+ ... while the results suggested that of the three nucleoside analogues evaluated in monotherapy, ddI was the most potent. ...
  http://www.readabstracts.com/Health/Antiviral-activity-of-nucleoside-analogues-during-short-course-monotherapy-or-dual-therapy-Its-role-.html
*  Study to Evaluate the Replacement of Reverse Transcriptase Nucleoside/Nucleotide Inhibitors by Nevirapine in Patients on Triple...
RTNI (reverse transcriptase nucleoside inhibitors) are a regular part of most antiretroviral combinations. The presence of a ... Study to Evaluate the Replacement of Reverse Transcriptase Nucleoside/Nucleotide Inhibitors by Nevirapine in Patients on Triple ... Substitution by Nevirapine in HIV-1 Infected Patients on Triple Treatment of Reverse Transcriptase Nucleoside/Nucleotide ... Patients on triple treatment with 3 nucleoside analogues or transcriptase nucleotide inhibitors in virological suppression. ...
  https://clinicaltrials.gov/show/NCT00415090?order=460
*  Virologic Responses To New Nucleoside Regimens After Prolonged ZDV or ddI Monotherapy - Full Text View - ClinicalTrials.gov
Virologic Responses To New Nucleoside Regimens After Prolonged ZDV or ddI Monotherapy. The safety and scientific validity of ... Virologic Responses To New Nucleoside Regimens After Prolonged ZDV or ddI Monotherapy. ... and resistance are thought to determine the durability of virologic and clinical response to nucleoside reverse transcriptase ... and resistance are thought to determine the durability of virologic and clinical response to nucleoside reverse transcriptase ...
  https://clinicaltrials.gov/show/NCT00000831?order=137
*  British Library EThOS: Design, synthesis and biological evaluation of novel bioactive nucleosides and nucleotides
Bicyclic nucleoside analogues are a new class of anti-varicella zoster agents of which Cfl743 is the most potent anti-varicella ... One of the major issues related to nucleoside analogues is the emergence of resistance due to a lack of bioactivation to the ... At the present there are 36 approved antiviral drugs in the UK of which half are nucleoside analogues. However, the emergence ... These striking results prompted us to investigate other different nucleoside analogues, through a virtual screening using ...
  http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.584729
*  Early Response to Interferon Combined Short-Term Nucleoside Analogue Therapy in HBeAg(+) Chronic Hepatitis B - Full Text View -...
And nucleoside analogue is added for 12 weeks.. Drug: interferon α plus nucleoside analogue Standard dose of interferon is used ... After nucleoside analogue is added for 3 months, HBV DNA is tested again. If negative, stop nucleoside analogue and use ... After nucleoside analogue is added for 3 months, HBV DNA is tested again. If negative, stop nucleoside analogue and use ... If HBV DNA is still positive, change to another nucleoside analogue or add another nucleoside analogue. ...
  https://clinicaltrials.gov/ct2/show/study/NCT00860626?view=record
*  Long-Term Mitochondrial Toxicity in HIV-Uninfected Infants Born to HIV-Infected Mothers
Most antiretroviral nucleoside analog drugs are dideoxy-type nucleosides that exert their antiretroviral properties after ... reported several nucleoside analog-exposed children between the ages of 7 months and 4.4 years with clinical mitochondrial ... Until recently, similar nucleoside analog-induced mitochondrial toxicity was thought not to occur in HIV-uninfected infants ... A number of studies have concluded that there are no persistent clinical changes in nucleoside analog-exposed infants compared ...
  http://www.natap.org/2003/june/062303_4.htm
*  Nucleoside-specific suppression in MRL/MP +/+ mice. - Semantic Scholar
... whether nucleoside-conjugated spleen cells are able to induce specific nonresponsiveness to T-dependent nucleoside antigens in ... The results show that nonresponsiveness to nucleoside antigens is inducable in male, but not in female, MRL/n mice. ... Treatment of male MRL/n mice with nucleoside-conjugated spleen cells (NSC) appeared to attenuate the progress of autoimmune ... The induction of nucleoside-specific nonresponsiveness was further studied in the autoimmune strain MRL/MP +/+ (MRL/n). ...
  https://www.semanticscholar.org/paper/Nucleoside-specific-suppression-in-MRL-MP-mice-Giroir-Raps/6a5685f2ba06c3068a06426a4ae421ffbaee1222
*  dnk - Deoxynucleoside kinase - Drosophila melanogaster (Fruit fly) - dnk gene & protein
Several anti-viral and anti-cancer nucleoside analogs are also efficiently phosphorylated. ... Specificity is higher for pyrimidine nucleosides. Several anti-viral and anti-cancer nucleoside analogs are also efficiently ... nucleoside diphosphate phosphorylation Source: UniProtKB ,p>Inferred from Direct Assay,/p> ,p>Used to indicate a direct assay ...
  http://www.uniprot.org/uniprot/Q9XZT6
*  中国科学院大连化学物理研究所机构知识库(DICP OpenIR): Determination of urinary nucleosides by direct injection and coupled-column
Urinary nucleosides analysis can be carried out by this procedure in 50 min requiring only pH adjustment and the protein ... Determination of urinary nucleosides was performed on Col-2 column by using a linear gradient elution comprising 25 mmol/L ... coupled-column ; urinary nucleosides ; high-performance liquid chromatography 刊名: JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL ... Determination of urinary nucleosides by direct injection and coupled-column high-performance liquid chromatography[J]. JOURNAL ...
  http://cas-ir.dicp.ac.cn/handle/321008/92895
*  Arabinosyl nucleosides - Wikipedia
Arabinosyl nucleosides are derivatives of the nucleosides. They contain - in contrast to most nucleosides - instead of the β-D- ... "Rational design of arabinosyl nucleosides as antitumor and antiviral agents", Jpn J Antibiot. 1977 Dec;30 Suppl:104-120; PMID ...
  https://en.wikipedia.org/wiki/Arabinosyl_nucleosides
*  Synthesis of nucleosides - Wikipedia
Heating the blocked nucleoside in Eq. (6) in the presence of a protected sugar chloride provides the nucleoside in 59% yield. ... 4)). Glycosylation of thymine with protected 1-acetoxy ribose produced 60% of the N1 nucleoside and 23% of the N3 nucleoside. ... yielding the desired β-nucleoside 2. A second reaction of this nucleoside with 1 generates bis(riboside) 3. Depending on the ... is the most common method for forming nucleosides in this manner. Nucleosides are typically synthesized through the coupling of ...
  https://en.wikipedia.org/wiki/Synthesis_of_nucleosides
*  Nucleoside - Wikipedia
While a nucleoside is a nucleobase linked to a sugar, a nucleotide is composed of a nucleoside and one or more phosphate groups ... In a nucleoside, the base is bound to either ribose or deoxyribose via a beta-glycosidic linkage. Examples of nucleosides ... Nucleosides are glycosylamines that can be thought of as nucleotides without a phosphate group. A nucleoside consists simply of ... into nucleosides (such as thymidine) and phosphate. The nucleosides, in turn, are subsequently broken down: in the lumen of the ...
  https://en.wikipedia.org/wiki/Nucleoside
*  Nucleosides, Nucleotides & Nucleic Acids - Wikipedia
Nucleosides, Nucleotides & Nucleic Acids is a monthly academic journal published by Taylor & Francis since 2000, continuing the ... earlier Nucleosides and Nucleotides in series. It discusses topics relating to the biochemistry of molecules in these classes. ...
  https://en.wikipedia.org/wiki/Nucleosides,_Nucleotides_&_Nucleic_Acids
*  Nucleoside phosphoramidite - Wikipedia
Nucleoside phosphoramidites are derivatives of natural or synthetic nucleosides. They are used to synthesize oligonucleotides, ... nucleosides modified at the 2'-position (OMe, protected NH2, F), nucleosides containing non-canonical bases (hypoxanthine and ... derivatives of nucleosides (nucleoside phosphoramidites) that serve as building blocks in phosphite triester methodology. To ... RO)2P-N(R1)2 + R2-N3 + H2O ---- (RO)2P(=O)-N(R1)2 + R2-NH2 + N2; The naturally occurring nucleotides (nucleoside-3'- or 5'- ...
  https://en.wikipedia.org/wiki/Nucleoside_phosphoramidite
*  Nucleoside triphosphate - Wikipedia
Nucleoside analogues are nucleosides that are structurally similar (analogous) to the nucleosides used in DNA and RNA synthesis ... Nucleoside analogues may also be used to treat viral infections. For example, azidothymidine (AZT) is a nucleoside analogue ... Nucleoside triphosphates cannot be absorbed well, so all nucleoside triphosphates are typically made de novo. The synthesis of ... Nucleoside triphosphates that contain ribose as the sugar are conventionally abbreviated as NTPs, while nucleoside ...
  https://en.wikipedia.org/wiki/Nucleoside_triphosphate
*  Nucleoside transporter - Wikipedia
Nucleoside transporters (NTs) are a group of membrane transport proteins which transport nucleoside substrates like adenosine ... There are two known types of nucleoside transporters, concentrative nucleoside transporters (CNTs; SLC28) and equilibrative ... "Physiological and pharmacological roles of nucleoside transporter proteins". Nucleosides, Nucleotides & Nucleic Acids. 27 (6): ... Baldwin SA, Beal PR, Yao SY, King AE, Cass CE, Young JD (February 2004). "The equilibrative nucleoside transporter family, ...
  https://en.wikipedia.org/wiki/Nucleoside_transporter
*  Nucleoside phosphotransferase - Wikipedia
In enzymology, a nucleoside phosphotransferase (EC 2.7.1.77) is an enzyme that catalyzes the chemical reaction a nucleotide + a ... The systematic name of this enzyme class is nucleotide:nucleoside 5'-phosphotransferase. Other names in common use include ... Prasher DC, Carr MC, Ives DH, Tsai TC, Frey PA (1982). "Nucleoside phosphotransferase from barley. Characterization and ... Brunngraber EF, Chargaff E (1967). "Purification and properties of a nucleoside phosphotransferase from carrot". J. Biol. Chem ...
  https://en.wikipedia.org/wiki/Nucleoside_phosphotransferase
*  Carbocyclic nucleoside - Wikipedia
Carbocyclic nucleosides were originally limited to a five-membered ring system, matching the ring-size of the nucleosides; ... Carbocyclic nucleosides (also referred to as carbanucleosides) are nucleoside analogues in which a methylene group has replaced ... There are two approaches used in the synthesis of carbocyclic nucleosides. Linear approaches to chiral carbocyclic nucleosides ... Zhu XF (March 2000). "The latest progress in the synthesis of carbocyclic nucleosides". Nucleosides, nucleotides & nucleic ...
  https://en.wikipedia.org/wiki/Carbocyclic_nucleoside
*  Nucleoside-diphosphatase - Wikipedia
... type B nucleoside diphosphatase, GDPase, CDPase, nucleoside 5'-diphosphatase, type L nucleoside diphosphatase, NDPase, and ... In enzymology, a nucleoside-diphosphatase (EC 3.6.1.6) is an enzyme that catalyzes the chemical reaction a nucleoside ... The systematic name of this enzyme class is nucleoside-diphosphate phosphohydrolase. Other names in common use include ... GIBSON DM, AYENGAR P, SANADI DR (1955). "A phosphatase specific for nucleoside diphosphates". Biochim. Biophys. Acta. 16 (4): ...
  https://en.wikipedia.org/wiki/Nucleoside-diphosphatase
*  Nucleoside-triphosphatase - Wikipedia
Other names in common use include nucleoside triphosphate phosphohydrolase, nucleoside-5-triphosphate phosphohydrolase, and ... In enzymology, a nucleoside-triphosphatase (NTPase) (EC 3.6.1.15) is an enzyme that catalyzes the chemical reaction NTP + H2O ... LEWIS M, WEISSMAN S (1965). "PROPERTIES OF A SOLUBLE NUCLEOSIDE TRIPHOSPHATASE ACTIVITY IN MAMMALIAN LIVER". Arch. Biochem. ... Matsushita S, Raacke ID (1968). "Purification of nucleoside triphosphatases from pea seedling ribosomes". Biochim. Biophys. ...
  https://en.wikipedia.org/wiki/Nucleoside-triphosphatase