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*  Lirias: Expression of the inducible isoform of nitric oxide synthase in the retinas of human subjects with diabetes mellitus
... remodeling of the diseased retina and that high concentrations of nitric oxide produced by inducible nitric oxide synthase ... PURPOSE: Inducible nitric oxide synthase has been implicated in the pathogenesis of cerebral ischemic damage, in the angiogenic ... This study was undertaken to determine whether inducible nitric oxide synthase is present in the retinas from human subjects ... Expression of the inducible isoform of nitric oxide synthase in the retinas of human subjects with diabetes mellitus. ...
  https://lirias.kuleuven.be/handle/123456789/28018
*  IJMS | Free Full-Text | Pu-erh Tea Reduces Nitric Oxide Levels in Rats by Inhibiting Inducible Nitric Oxide Synthase Expression...
To address this question we examined the effects of pu-erh tea on nitric oxide synthase (NOS) genes. Cohorts of rats were ... tea or polysaccharides had lower levels of NO which corresponded with the down-regulation of inducible nitric oxide synthase ( ... Five experimental groups were injected with lipopolysaccharides (LPS) to induce nitric oxide (NO) production, while the ... although it is unclear about which component is associated with the down regulation of nitric oxide levels or how this process ...
  http://www.mdpi.com/1422-0067/13/6/7174
*  Nitric oxide synthase - Wikipedia
Biological functions of nitric oxide Nitric-oxide synthase (NAD(P)H-dependent) Nitric oxide synthase 2 (inducible) PDB: 3N5P​; ... Nitric oxide synthases (EC 1.14.13.39) (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L- ... "Nitric oxide down-regulates hepatocyte-inducible nitric oxide synthase gene expression". Arch Surg. 132 (11): 1177-83. doi: ... which is then recaptured to enable nitric oxide release. The first nitric oxide synthase to be identified was found in neuronal ...
  https://en.wikipedia.org/wiki/Nitric_oxide_synthase
*  Patent US6147109 - Upregulation of Type III endothelial cell Nitric Oxide Synthase by HMG-CoA ... - Google Patents
HMG-CoA reductase inhibitors are found to upregulate endothelial cell Nitric Oxide Synthase activity through a mechanism other ... preventing conditions that result from the abnormally low expression and/or activity of endothelial cell Nitric Oxide Synthase ... Nitric Oxide Synthase is the enzyme that catalyzes the reaction that produces nitric oxide from the substrate L-arginine. As ... cell Nitric Oxide Synthase and/or a nonHMG-CoA reductase inhibitor agent that increases endothelial cell Nitric Oxide Synthase ...
  http://www.google.com/patents/US6147109?dq=%22robert+sheehan%22
*  Protein Kinase C Mediates Lipopolysaccharide- and Phorbol-Induced Nitric-Oxide Synthase Activity and Cellular Injury in the Rat...
nitric-oxide synthase. NO. nitric oxide. iNOS. inducible nitric-oxide synthase. PKC. protein kinase C. PMA. phorbol-12- ... 1993) The induction of nitric oxide synthase and intestinal vascular permeability by endotoxin in the rat. Br J Pharmacol 110: ... 1994) Nitric oxide synthase activity, viability and cyclic GMP levels in rat colonic epithelial cells: Effect of endotoxin ... 1995) PKC mediates LPS- and phorbol-induced cardiac cell nitric oxide synthase activity and hypocontractility. Am J Physiol 269 ...
  http://jpet.aspetjournals.org/content/295/3/1249.long
*  Nitric oxide synthase activity is increased in relation to the severity of liver dysfunction | Clinical Science
Nitric oxide synthase activity was measured using the conversion of oxyhaemoglobin to methaemoglobin by nitric oxide and ... The hyperdynamic circulation of cirrhosis has been linked to nitric oxide.. 2.We measured neutrophil nitric oxide synthase ... Nitric oxide synthase activity is increased in relation to the severity of liver dysfunction. Helen F. GALLEY, David ... 5.Our results show that nitric oxide synthase activity increases with increasing Child-Pugh score and is associated with the ...
  http://www.clinsci.org/content/95/3/355
*  Modulation of nerve growth factor-induced activation of MAP kinase in PC12 cells by inhibitors of nitric oxide synthase. -...
... isozymes leading to enhanced production of nitric oxide (NO). NOS inhibitors attenuate NGF-mediated increases in cholinergic ... increases expression of nitric oxide synthase (NOS) isozymes leading to enhanced production of nitric oxide (NO). NOS ... Modulation of nerve growth factor-induced activation of MAP kinase in PC12 cells by inhibitors of nitric oxide synthase.. *. ... Nitric oxide synthase mediates PC12 differentiation induced by the surface topography of nanostructured TiO2. *Margherita ...
  https://www.semanticscholar.org/paper/Modulation-of-nerve-growth-factor-induced-activati-Kalisch-Demeris/eafe1baa974b84980306fccf8e386a6ecb9eb33b
*  Patent US6180597 - Upregulation of Type III endothelial cell nitric oxide synthase by rho ... - Google Patents
... rho GTPase function inhibitors are found to upregulate endothelial cell Nitric Oxide Synthase activity. As a result, rho GTPase ... preventing conditions that result from the abnormally low expression and/or activity of endothelial cell Nitric Oxide Synthase ... Nitric Oxide Synthase is the enzyme that catalyzes the reaction that produces nitric oxide from the substrate L-arginine. As ... Nitric Oxide Synthase and/or a non-rho GTPase function inhibitor agent that increases endothelial cell Nitric Oxide Synthase ...
  http://www.google.ca/patents/US6180597
*  In vivo expression profile of an endothelial nitric oxide synthase promoter-reporter transgene.
... is primarily attributable to constitutive expression of the endothelial nitric oxide synthase (eNOS) gene. Although a more ... Nitric Oxide Synthase / genetics*. Nitric Oxide Synthase Type II. Nitric Oxide Synthase Type III. Plasmids. Promoter Regions, ... EC 1.14.13.39/Nitric Oxide Synthase; EC 1.14.13.39/Nitric Oxide Synthase Type II; EC 1.14.13.39/Nitric Oxide Synthase Type III ... Endothelium-derived nitric oxide (NO) is primarily attributable to constitutive expression of the endothelial nitric oxide ...
  http://www.biomedsearch.com/nih/In-vivo-expression-profile-endothelial/10749733.html
*  Adventitial Gene Transfer of Recombinant Endothelial Nitric Oxide Synthase to Rabbit Carotid Arteries Alters Vascular...
Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues. Proc Natl Acad Sci U S A. ... Busse R, Mulsch A. Induction of nitric oxide synthase by cytokines in vascular smooth muscle cells. FEBS Lett. 1990;275:87-90. ... Neuronal NADPH diaphorase is a nitric oxide synthase. Proc Natl Acad Sci U S A. 1991;88:2811-2814. ... Gene therapy inhibiting neointimal vascular lesion: in vivo transfer of endothelial cell nitric oxide synthase gene. Proc Natl ...
  http://circ.ahajournals.org/content/96/7/2254
*  IJMS | Free Full-Text | Elevation of Inducible Nitric Oxide Synthase and Cyclooxygenase-2 Expression in the Mouse Brain after...
The nitric oxide (NO) level and nitric oxide synthase (NOS) activity were also measured by biochemical analyses. The results ... inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), was evaluated by immunohistochemistry and immunoblotting ...
  http://www.mdpi.com/1422-0067/9/10/1977/notes
*  Dexamethasone Up-Regulates a Constitutive Nitric Oxide Synthase in Cerebellar Astrocytes but Not in Granule Cells in Culture -...
... up-regulate astroglial calcium-dependent nitric oxide synthase while preventing expression of inducible nitric oxide synthase ... A. Law, J. O'Donnell, S. Gauthier, R. Quirion, Neuronal and inducible nitric oxide synthase expressions and activities in the ... ALEJANDRO BERRA, SABRINA GANZINELLI, MARIO SARAVIA, ENRI BORDA, LEONOR STERIN-BORDA, Inducible nitric oxide synthase subserves ... Dexamethasone Up-Regulates a Constitutive Nitric Oxide Synthase in Cerebellar Astrocytes but Not in Granule Cells in Culture. ...
  http://onlinelibrary.wiley.com/doi/10.1046/j.1471-4159.1995.64010447.x/full
*  Systemic nitric oxide production in human malaria: II. Analysis of mononuclear cell nitric oxide synthase type 2 antigen...
Systemic nitric oxide production in human malaria: II. Analysis of mononuclear cell nitric oxide synthase type 2 antigen ... Systemic nitric oxide production in human malaria: II. Analysis of mononuclear cell nitric oxide synthase type 2 antigen ... Systemic nitric oxide production in human malaria: II. Analysis of mononuclear cell nitric oxide synthase type 2 antigen ... As described in Chapter 42, niric oxide (NO) is synthesized from the amino acid l-arginine by the actions of a family of enymes ...
  http://espace.cdu.edu.au/view/cdu:4805
*  Effect of 17-? Estradiol on the Expression of Inducible Nitric oxide Synthase in Parent and Tamoxifen Resistant T47D Breast...
Estrogen is also thought to modulate nitric oxide (NO) in human breast tumor tissue via regulation of inducible nitric oxide ... synthase (iNOS). Objectives of this study were to determine whether estradiol (E2) affects iNOS expression level in breast ... Human colon cancer cell lines show a divers pattern of nitric oxide synthase expression and nitric oxide generation. Brit. J. ... expression of inducible nitric oxide synthase and effect of tamoxifen and phorbol ester on nitric oxide production. Cancer Let ...
  http://ijpr.sbmu.ac.ir/article_800.html
*  Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitric oxide synthase and gastric mucosal...
... and the expression of inducible nitric oxide synthase (NOS-2) activity and soluble tumor necrosis factor-α (TNF-α). Groups of ... enhancement in nitric oxide generation, and amplification of apoptotic events. We applied the animal model of H. pylori - ... Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitric oxide synthase and gastric mucosal ... Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitric oxide synthase and gastric mucosal ...
  http://booksandjournals.brillonline.com/content/journals/10.1163/156856000750264438
*  What is Nitric Oxide Synthase? (with pictures)
Nitric oxide synthase is a small molecule with a double covalent bond between nitrogen and oxygen atoms. In most cases, nitric ... Its production in epithelial cells is controlled by epithelial nitric oxide synthase (eNOS). Nitric oxide synthase is bound in ... Inducible nitric oxide synthase (iNOS) is employed by the body to stall the growth of cells in gastric epithelial, breast, and ... Neuronal nitric oxide synthase (nNOS) is continuously recycled to produce NO, as the NO is stable for mere seconds before being ...
  https://www.wisegeek.com/what-is-nitric-oxide-synthase.htm
*  Structures: Nitric-oxide synthase, eukaryote (IPR012144) | InterPro | EMBL-EBI
Structures: Nitric-oxide synthase, eukaryote (IPR012144). PDBe. The Protein Data Bank (PDB) is a repository for the 3-D ...
  http://www.ebi.ac.uk/interpro/entry/IPR012144/structures
*  nitric-oxide synthase, inducible Protein Superfamily Detail
Term: nitric-oxide synthase, inducible. ID: PIRSF000333 Mouse Protein Superfamily Annotations. Select one or more mouse PIRSF ...
  http://www.informatics.jax.org/vocab/pirsf/PIRSF000333
*  Proteins matched: Nitric oxide synthase, N-terminal (IPR004030) | InterPro | EMBL-EBI
Proteins matched: Nitric oxide synthase, N-terminal (IPR004030) This domain is found in the following proteins: Showing 1 to 20 ... Nitric oxide synthase, endothelial. Ovis aries (Sheep). Loading... P79290 Nitric oxide synthase, inducible. Sus scrofa (Pig). ... Nitric oxide synthase, brain. Homo sapiens (Human). Loading... P29476 3D Nitric oxide synthase, brain. Rattus norvegicus (Rat) ... Nitric oxide synthase, inducible. Mus musculus (Mouse). Loading... P35228 3D Nitric oxide synthase, inducible. Homo sapiens ( ...
  http://www.ebi.ac.uk/interpro/entry/IPR004030/proteins-matched
*  Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation | PNAS
Nitric oxide is derived from L-arginine by isoforms of nitric-oxide synthase (NOS; EC 1.14.13.39): constitutive (cNOS; calcium- ... Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation. J R Vane, J A Mitchell, I Appleton, A Tomlinson ... Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation. J R Vane, J A Mitchell, I Appleton, A Tomlinson ... Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation. J R Vane, J A Mitchell, I Appleton, A Tomlinson ...
  http://www.pnas.org/content/91/6/2046
*  Uncoupling of Vascular Nitric Oxide Synthase Caused by Intermittent Hypoxia
... Mohammad Badran,1 Bisher Abuyassin,1 Saeid Golbidi ... U. Förstermann and T. Münzel, "Endothelial nitric oxide synthase in vascular disease: from marvel to menace," Circulation, vol ... A. Daiber, M. Oelze, S. Daub et al., "Vascular redox signaling, redox switches in endothelial nitric oxide synthase (eNOS ... S. Varadharaj, K. Porter, A. Pleister et al., "Endothelial nitric oxide synthase uncoupling: a novel pathway in OSA induced ...
  https://www.hindawi.com/journals/omcl/2016/2354870/
*  Oxidative Stress, Nitric Oxide Synthase, and Superoxide Dismutase | Hypertension
Oxidative Stress, Nitric Oxide Synthase, and Superoxide Dismutase. A Matter of Imbalance Underlies Endothelial Dysfunction in ... Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. J Clin Invest. ... oxidase and uncoupling of endothelial nitric oxide synthase (eNOS). There is also increased expression of endothelin-1 (ET-1), ... effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling. Circulation. 2006; 114: ...
  http://hyper.ahajournals.org/content/51/1/31
*  Nitric Oxide Synthase Radiometric Assay Kit from Cayman Chemical
... ,The NOS assay kit measures NOS activity by monitoring the ... Mouse Anti-Thymidylate Synthase Monoclonal Antibody, Unconjugated, Clone 3A7.A11 from Abcam. 2. Mouse Anti-Bovine Complex V ( ... F1F0 ATP Synthase) Heart Mitochondria Monoclonal Antibody, Unconjugated, Clone 12F4AD8AF8 from MitoScience LLC. 3. Histone ...
  http://www.bio-medicine.org/biology-products/Nitric-Oxide-Synthase-Radiometric-Assay-Kit-from-Cayman-Chemical-3566-1/
*  Endothelial Nitric Oxide Synthase Genotype and Ischemic Heart Disease | Circulation
Plasma nitric oxide concentrations and nitric oxide synthase gene polymorphisms in coronary artery disease. Clin Chem. 2000; 46 ... Genetic contribution of the endothelial constitutive nitric oxide synthase gene to plasma nitric oxide levels. Arterioscler ... Endothelial Nitric Oxide Synthase Genotype and Ischemic Heart Disease. Juan P. Casas, Leonelo E. Bautista, Steve E. Humphries ... Endothelial Nitric Oxide Synthase Genotype and Ischemic Heart Disease. Juan P. Casas, Leonelo E. Bautista, Steve E. Humphries ...
  http://circ.ahajournals.org/content/109/11/1359
*  Nitroglycerine-Induced Nitrate Tolerance Compromises Propofol Protection of the Endothelial Cells against TNF-α: The Role of...
W. H. Kaesemeyer, A. A. Ogonowski, L. Jin, R. B. Caldwell, and R. W. Caldwell, "Endothelial nitric oxide synthase is a site of ... nitric oxide synthase-dependent pathway in diabetic cardiomyocytes," Anesthesiology, vol. 104, no. 5, pp. 978-987, 2006. View ... S. Selemidis, G. J. Dusting, H. Peshavariya, B. K. Kemp-Harper, and G. R. Drummond, "Nitric oxide suppresses NADPH oxidase- ... dysfunction and tolerance involve adverse phosphorylation and S-glutathionylation of endothelial nitric oxide synthase: ...
  https://www.hindawi.com/journals/omcl/2013/678484/ref/