*  Pediatric Neuroblastoma: Background, Pathophysiology, Epidemiology
Neuroblastoma is the most common extracranial solid tumor of infancy. It is an embryonal malignancy of the sympathetic nervous ... Histologic subtypes of neuroblastoma are shown in the image below.. Histologic subtypes of neuroblastoma. Top right panel, ... Histologic subtypes of neuroblastoma. Top right panel, neuroblastoma: A monotonous population of hyperchromatic cells with ... Improved Survival of Children with Neuroblastoma Between 1979 and 2005: A Report of the Italian Neuroblastoma Registry. J Clin ...
  https://emedicine.medscape.com/article/988284-overview
*  Regulatory Volume Decrease and Intracellular Ca2+ in Murine Neuroblastoma Cells Studied with Fluorescent Probes | JGP
We found that in single N1E-115 neuroblastoma cells and in NG108-15 hybrid neuroblastoma × glioma cells, there is a close ... Two murine neural cell lines maintained in culture, N1E-115 neuroblastoma and neuroblastoma × glioma NG108-15, were used in the ... 1995) Swelling-induced chloride currents in neuroblastoma cells are calcium dependent. J Neurosci 15:3662-3666, pmid:7751936.. ... The neuroblastoma × glioma hybrid cells NG108-15 are hybrid cells obtained from a rat glioma cell line and a mouse ...
  http://jgp.rupress.org/content/112/2/145
*  A Phase I/II Study Of Immunization With Lymphotactin And Interleukin 2 Gene Modified Neuroblastoma Tumor Cells - Full Text View...
TREATMENT PLAN: Standard Chemotherapy for Neuroblastoma: Standard therapy for neuroblastoma is given in 3 phases: induction, ... irradiated neuroblastoma cell line (SKNLP) to a studied, safe dose of a gene modified, IL-2/Lptn secreting neuroblastoma cell ... Neuroblastoma Biological: SJNB-JF-IL2 and SJNB-JF-Lptn vaccine Biological: SKNLP Vaccine Phase 1 Phase 2 ... A Phase I/II Study Of Immunization With Lymphotactin And Interleukin 2 Gene Modified Neuroblastoma Tumor Cells (CHESAT). This ...
  https://clinicaltrials.gov/ct2/show/NCT00703222
*  Omega-3 fatty acid supplementation delays the progression of neuroblastoma in vivo
DHA delayed neuroblastoma xenograft development and inhibited the growth of established neuroblastoma xenografts in athymic ... neuroblastoma, omega-3 fatty acids, docosahexaenoic acid, pediatric cancer, preclinical in vivo models National Category ... We have previously shown that the omega-3 fatty acid docosahexaenoic acid (DHA) induces apoptosis of neuroblastoma cells in ... In our study, the effects of DHA supplementation on neuroblastoma tumor growth in vivo were investigated using two ...
  http://uu.diva-portal.org/smash/record.jsf?pid=diva2:402465
*  The novel melphalan prodrug J1 inhibits neuroblastoma growth in vitro and in vivo | Molecular Cancer Therapeutics
... was evaluated in neuroblastoma models in vitro and in vivo. Seven neuroblastoma cell lines with various levels of drug ... and five cytotoxic drugs commonly used in the treatment of neuroblastoma in seven neuroblastoma cell lines. The increase in ... and five cytotoxic drugs commonly used in the treatment of patients with neuroblastoma was investigated in seven neuroblastoma ... The novel melphalan prodrug J1 inhibits neuroblastoma growth in vitro and in vivo. Malin Wickström, John Inge Johnsen, Frida ...
  http://mct.aacrjournals.org/content/6/9/2409.long
*  Efficacy of Prophylactic Itraconazole in High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantation - Full...
Neuroblastoma. Mycoses. Wilms Tumor. Retinoblastoma. Central Nervous System Neoplasms. Nervous System Neoplasms. Neoplasms by ... Efficacy of HDCT and ASCT has been well demonstrated in high-risk neuroblastoma, high-risk brain tumor, and recurrent pediatric ... Outcome in advanced or high-risk pediatric solid tumor such as advanced neuroblastoma, high-risk brain tumor, or recurrent ... Genetic and Rare Diseases Information Center resources: Neuroblastoma Retinoblastoma Wilms' Tumor Neuroepithelioma ...
  https://clinicaltrials.gov/show/NCT00336531
*  Neuroblastoma: contemporary management | ADC Education & Practice Edition
Neuroblastoma accounts for more than 7% of malignancies in patients younger than 15 years and around 15% of all paediatric ... Neuroblastoma is the most frequently diagnosed extracranial solid tumour in childhood. While a subset of tumours show ... Neuroblastoma is the most common extracranial solid tumour in childhood and the most frequently diagnosed neoplasm during ... Neuroblastoma is often described as "enigmatic" and "unpredictable" because of the broad spectrum of clinical behaviour ranging ...
  http://ep.bmj.com/content/94/6/177
*  Gene Therapy in Treating Children With Refractory or Recurrent Neuroblastoma - Full Text View - ClinicalTrials.gov
Gene Therapy in Treating Children With Refractory or Recurrent Neuroblastoma. The safety and scientific validity of this study ... Gene Modified Autologous or Partially Matched Allogeneic Neuroblastoma Cells for Treatment of Relapsed/Refractory Neuroblastoma ... Neuroblastoma Biological: gene-modified tumor cell vaccine therapy Biological: interleukin-2 gene Phase 1 ... MedlinePlus related topics: Genes and Gene Therapy Neuroblastoma Genetic and Rare Diseases Information Center resources: ...
  https://clinicaltrials.gov/ct2/show/NCT00002748
*  PD-L1 Is a Therapeutic Target of the Bromodomain Inhibitor JQ1 and, Combined with HLA Class I, a Promising Prognostic Biomarker...
Experimental Design: In situ IHC staining for PD-L1, HLA class I, PD-1, and LAG3 was assessed in 77 neuroblastoma specimens, ... Surface expression of PD-L1 was evaluated by flow cytometry and IHC in neuroblastoma cell lines and tumors genetically and/or ... A dataset of 477 human primary neuroblastomas from GEO and ArrayExpress databases was explored for PD-L1, MYC, and MYCN ... Conclusions: The combination of PD-L1 and HLA class I represents a novel prognostic biomarker for neuroblastoma. Pharmacologic ...
  http://clincancerres.aacrjournals.org/content/23/15/4462
*  Targeting suppressive myeloid cells potentiates checkpoint inhibitors to control spontaneous neuroblastoma | Clinical Cancer...
Purpose: Neuroblastoma is the most common extracranial solid cancer type in childhood and high-risk patients have poor ... In vitro, neuroblastoma-derived factors interfere with early development of myeloid cells and enable suppressive functions on ... Neuroblastoma-driven inflammation contributes to the induction of suppressive myeloid cells that hamper efficient anti-tumor ... Targeting suppressive myeloid cells potentiates checkpoint inhibitors to control spontaneous neuroblastoma. Yumeng Mao, Nina ...
  http://clincancerres.aacrjournals.org/content/early/2016/03/08/1078-0432.CCR-15-1912
*  Celecoxib Prevents Neuroblastoma Tumor Development and Potentiates the Effect of Chemotherapeutic Drugs In vitro and In vivo
... ... Purpose: Neuroblastoma is the most common and deadly solid tumor of childhood. Cyclooxygenase-2 is expressed in clinical ... Neuroblastoma, COX-2 inhibitor, prevention, chemotherapeutic drugs, synergy National Category Medical and Health Sciences ... Experimental Design: Neuroblastoma cell cytotoxicity of chemotherapeutic drugs in combination with celecoxib was examined. In ...
  http://uu.diva-portal.org/smash/record.jsf?pid=diva2:53794
*  Biomarkers in Young Patients With Neuroblastoma - Full Text View - ClinicalTrials.gov
disseminated neuroblastoma. localized resectable neuroblastoma. localized unresectable neuroblastoma. regional neuroblastoma. ... MedlinePlus related topics: Neuroblastoma Genetic and Rare Diseases Information Center resources: Neuroblastoma ... 50 tumor samples from patients with low-risk primary neuroblastoma, and 30 human neuroblastoma-derived cell lines will be ... Biomarkers in Young Patients With Neuroblastoma. The safety and scientific validity of this study is the responsibility of the ...
  https://clinicaltrials.gov/ct2/show/NCT01169376?cond=%22Neuroblastoma%22&rank=18
*  SK N SH (human neuroblastoma cell line) lysate (ab3956)
... human neuroblastoma cell line) whole cell lysate. ab3956 has been validated in western blot. Abcam now offers a 12-month ... Cell line: SK-N-SH (Human neuroblastoma).. Growth media: Minimum essential medium Eagle with 2 mM L-glutamine and Earle's BSS ...
  http://www.abcam.com/sk-n-sh-whole-cell-lysate-ab3956.html
*  Synthesis and Catabolism of {gamma}-Hydroxybutyrate in SH-SY5Y Human Neuroblastoma Cells - Mind in Science Blog
In this study we have used RNA interference to evaluate the role of AKR7A2 in GHB biosynthesis in human neuroblastoma SH-SY5Y ... Synthesis and Catabolism of {gamma}-Hydroxybutyrate in SH-SY5Y Human Neuroblastoma Cells. February 28, 2008. healingmindn ...
  http://mindscience.bioenergeticspectrum.com/index.php/2008/02/28/synthesis-and-catabolism-of-gamma-hydroxybutyrate-in-sh-sy5y-human-neuroblastoma-cells/
*  Neuroblastoma cells injected into experimental mature teratoma reveal a tropism for embryonic loose mesenchyme
neuroblastoma, human, in vivo, model, stem cells National Category Medical and Health Sciences Identifiers. URN: urn:nbn:se:uu: ... Neuroblastoma cells were never observed in areas with well-differentiated somatic tissue i.e. bone, muscle, gut or areas of ... Neuroblastoma cells injected into experimental mature teratoma reveal a tropism for embryonic loose mesenchyme. Jamil, S. ... teratoma can function as an experimental in vivo microenvironment instigating the growth of injected childhood neuroblastoma ( ...
  http://uu.diva-portal.org/smash/record.jsf?pid=diva2:646642
*  What Is Neuroblastoma? | Dana-Farber Cancer Institute
How is neuroblastoma diagnosed? Doctors may detect neuroblastoma by searching for signs of cancer through a urine test, bone ... What causes neuroblastoma?. The cause of neuroblastoma is not certain, but researchers believe it forms from neuroblasts, ... What are the symptoms of neuroblastoma?. Symptoms of neuroblastoma vary with the location and size of the tumor, and the ... Children with relapsed or refractory neuroblastoma may also receive MIBG therapy, which can be used to find neuroblastoma in ...
  http://blog.dana-farber.org/insight/2016/08/what-is-neuroblastoma/
*  neuroblastoma?? - Cancer - Condition | Our Health
Hi, I'm pretty new to this site and I was hoping you guys might be able to help. For the past year I have been pretty significantly sick and have been unable to get a confident answer. The most recent diagnosis POTS/dysautonomia, but I don't completly fit and even my neuro (who I'm told is top in this field) isn't sure. I've just been for a follow up with my endocrinologist and she gave me a 24hr urine collection. I was wondering what the chances that I could have a neuroblstoma or a pheocromocytoma are. I realize they are extremely rare - especially for my age (19). I would appreciate any help you could offer. Thank you.. Reply Follow This Thread Stop Following This Thread Flag this Discussion ...
  http://www.ourhealth.com/conditions/cancer/neuroblastoma
*  Neuroblastoma | SpringerLink
Neuroblastoma is a common solid tumor of infancy and childhood. It is uniquely characterized by a distinct natural history and ... Neuroblastoma in the newborn. A study of the Italian Neuroblastoma Registry. Eur J Cancer. 2009;45:3220-7.CrossRefPubMedGoogle ... Neurocytoma or neuroblastoma, a kind of tumor not generally recognized. J Exp Med. 1910;12:556-61.PubMedPubMedCentralCrossRef ... Neonatal neuroblastoma. Arch Dis Child Fetal Neonatal Ed. 1999;81:F134-7.PubMedPubMedCentralCrossRefGoogle Scholar ...
  https://link.springer.com/chapter/10.1007%2F978-1-4471-4721-3_57
*  Neuroblastoma | Encyclopedia.com
Neuroblastoma Definition Neuroblastoma is a type of cancer that usually originates either in the tissues of the adrenal gland [ ... Neuroblastoma Gale Encyclopedia of Cancer COPYRIGHT 2002 The Gale Group Inc.. Neuroblastoma. Definition. Neuroblastoma is a ... Neuroblastoma Gale Encyclopedia of Medicine, 3rd ed. COPYRIGHT 2006 Thomson Gale. Neuroblastoma. Definition. Neuroblastoma is a ... The causes of neuroblastoma are not precisely known. Current research holds that neuroblastomas develop when cells produced by ...
  https://www.encyclopedia.com/medicine/diseases-and-conditions/pathology/neuroblastoma
*  Neuroblastoma Prognosis
Neuroblastoma is difficult to detect in the early stages and the disease is often not identified until it is more advanced. In ... High-risk neuroblastomas are more likely to recur after treatment.. Those who survive neuroblastoma may develop certain ... Neuroblastoma is difficult to detect in the early stages and the disease is often not identified until it is more advanced. In ... http://www.nhs.uk/conditions/Neuroblastoma/Pages/Introduction.aspx. * www.cancer.org/acs/groups/cid/documents/webcontent/003125 ...
  https://www.news-medical.net/health/Neuroblastoma-Prognosis.aspx
*  Neuroblastoma - Everything2.com
A sarcoma which is made up of primitive neural tissue, developing most often in the brain or in the adrenal glands above the kidneys and frequently spre...
  https://everything2.com/title/Neuroblastoma
*  Neuroblastoma Genomics
Division of Neuroblastoma Genomics. PD Dr. Frank Westermann. Hierarchical cluster analysis with clinical covariates of 702 ... Neuroblastoma is the most common pediatric single-entity solid cancer derived from primitive cells of the peripheral ... Malfunction of the MYCN transcription factor is a key feature of neuroblastoma biology and is involved in almost every aspect ... In addition, we use high-throughput si/shRNA screens to disclose neuroblastoma-specific vulnerabilities associated with ...
  https://www.dkfz.de/en/neuroblastom-genomik/index.php
*  Neuroblastoma and Neuroblastic Tumors | SpringerLink
... including neuroblastoma, ganglioneuroblastoma, and ganglioneuroma are composed of biologically favorable and biologically ... International consensus for neuroblastoma molecular diagnostics: report from the International Neuroblastoma Risk Group (INRG) ... MYC family-driven neuroblastoma (including large-cell neuroblastoma) defined by augmented expression of MYCN and/or MYC protein ... Recent advances in neuroblastoma. N Engl J Med. 2010;362:2202-11.CrossRefPubMedPubMedCentralGoogle Scholar ...
  https://link.springer.com/chapter/10.1007%2F978-3-319-89626-7_8
*  Neuroblastoma - Pixdaus
Pixdaus.com is an environmental photo-bookmarking and sharing service. All the pictures are uploaded by users and the copyrights belong to the rightholders. You can request a removal using the Copyright flag link below each image if you find an image that shouldn't belong here ...
  http://pixdaus.com/neuroblastoma/items/tag/neuroblastoma/
*  Can Neuroblastoma Be Found Early?
Researchers have studied whether screening infants for neuroblastoma might result in earlier diagnosis and better treatment ... Can Neuroblastoma Be Found Early?. Researchers have studied whether screening infants for neuroblastoma might find these tumors ... One way to screen for neuroblastoma is to test children's urine for certain substances made by neuroblastoma tumors. (For more ... In rare instances, neuroblastoma is found before birth during an ultrasound, a test that uses sound waves to create an image of ...
  https://www.cancer.org/cancer/neuroblastoma/detection-diagnosis-staging/detection.html