*  Gentaur Molecular :FabGennix \ Neprilysin, WB control \ PC-NEPR
Neprilysin, WB control \ PC-NEPR for more molecular products just contact us ... Neprilysin-2) (NEP2) (NL2) (Neprilysin-like 1) (NL-1) (Neprilysin-like peptidase) (NEPLP) (Soluble secreted endopeptidase) [ ... Putative peptidase family m13 includes neprilysin. [] Putative peptidase family m13 includes neprilysin (Fragment). ... We have also other products like : Neprilysin, WB control Related products : Neprilysin, WB control ...
  http://www.antibody-antibodies.com/product_det.php?id=3098221&supplier=search&name=Neprilysin,%20WB%20control%20
*  Rat CD10/Neprilysin Gene ORF cDNA clone expression plasmid, N-His tag | SinoBiological
rat CD10/Neprilysin gene cDNA, cloning vector & expression plasmid, mutiple tags. Optimized for high expression in mammalian ... Rat CD10/Neprilysin Gene ORF cDNA clone expression plasmid, N-His tag on other vectors Rat CD10/Neprilysin Gene ORF cDNA clone ... Rat CD10/Neprilysin Gene ORF cDNA clone expression plasmid, C-OFPSpark tag. RG80288-ACR. $. 245. ... Rat CD10/Neprilysin Gene ORF cDNA clone expression plasmid, C-Flag tag. RG80288-CF. $. 215. ...
  http://www.sinobiological.com/Rat-MME-Gene-cDNA-Clone-
*  Anti-CD10/Neprilysin Antibody
Background for Neprilysin. CD10, also known as membrane metallo-endopeptidase, neutral endopeptidase(NEP), Neprilysin, or ... At Boster we strive to provide the best Anti-CD10/Neprilysin Antibody by testing all applications on non-spiked tissues and ... Neprilysin;3.4.24.11 ;Atriopeptidase;Common acute lymphocytic leukemia antigen;CALLA;Enkephalinase;Neutral endopeptidase 24.11; ... Rabbit IgG polyclonal antibody for Neprilysin(MME) detection. Tested with WB, IHC-P in Human;Mouse;Rat.. ...
  https://www.bosterbio.com/anti-cd10-picoband-trade-antibody-pb9058.html
*  MME - Neprilysin - Pongo abelii (Sumatran orangutan) - MME gene & protein
Neprilysin (EC:3.4.24.11By similarity. ,p>Manually curated information which has been propagated from a related experimentally ... sp,Q5RE69,NEP_PONAB Neprilysin OS=Pongo abelii OX=9601 GN=MME PE=2 SV=2 ...
  http://www.uniprot.org/uniprot/Q5RE69
*  Neprilysin Gene Transfer Reduces Human Amyloid Pathology in Transgenic Mice | Journal of Neuroscience
Neprilysin was detected in the brain homogenates by immunoblot (Fig. 2a). The expression of neprilysin was also detectable by ... Expression of neprilysin in mouse brains.a, Detection of human neprilysin expression by immunoblot. Lenti-GFP and saline ... Neprilysin activity assay. Neprilysin activity was measured as described previously (Li and Hersh, 1995). Briefly, whole cell ... To further investigate the role of neprilysin in amyloid deposition, a lentiviral vector expressing human neprilysin (Lenti-Nep ...
  http://www.jneurosci.org/content/23/6/1992.long
*  Neprilysin - Wikipedia
... the relationship between neprilysin expression and carcinogenesis remains obscure. In cancer biomarker studies, the neprilysin ... which thus depresses the activity of neprilysin and promotes aggregation of unprocessed amyloid beta. Declining neprilysin ... Neprilysin is expressed in a wide variety of tissues and is particularly abundant in kidney. It is also a common acute ... Because neprilysin is thought to be the rate-limiting step in amyloid beta degradation, it has been considered a potential ...
  https://en.wikipedia.org/wiki/Neprilysin
*  HIV-1 Transactivator Protein Induces ZO-1 and Neprilysin Dysfunction in Brain Endothelial Cells via the Ras Signaling Pathway
Exposure to Tat decreased protein and mRNA levels of zonula occludens- (ZO-) 1 and Aβ-degrading enzyme neprilysin (NEP) in HBEC ... HIV-1 Transactivator Protein Induces ZO-1 and Neprilysin Dysfunction in Brain Endothelial Cells via the Ras Signaling Pathway. ...
  https://www.hindawi.com/journals/omcl/2017/3160360/abs/
*  Abstract 13567: LCZ696, an Angiotensin Receptor Neprilysin Inhibitor, Provides Superior 24-hour Blood Pressure Reduction than...
Abstract 13567: LCZ696, an Angiotensin Receptor Neprilysin Inhibitor, Provides Superior 24-hour Blood Pressure Reduction than ... Abstract 13567: LCZ696, an Angiotensin Receptor Neprilysin Inhibitor, Provides Superior 24-hour Blood Pressure Reduction than ... Abstract 13567: LCZ696, an Angiotensin Receptor Neprilysin Inhibitor, Provides Superior 24-hour Blood Pressure Reduction than ... Abstract 13567: LCZ696, an Angiotensin Receptor Neprilysin Inhibitor, Provides Superior 24-hour Blood Pressure Reduction than ...
  http://circ.ahajournals.org/content/130/Suppl_2/A13567
*  Inhibition of neprilysin by infusion of thiorphan into the hippocampus causes an accumulation of amyloid β and impairment of...
Inhibition of neprilysin by infusion of thiorphan into the hippocampus causes an accumulation of amyloid β and impairment of ... Inhibition of neprilysin by infusion of thiorphan into the hippocampus causes an accumulation of amyloid β and impairment of ... Inhibition of neprilysin by infusion of thiorphan into the hippocampus causes an accumulation of amyloid β and impairment of ... Inhibition of neprilysin by infusion of thiorphan into the hippocampus causes an accumulation of amyloid β and impairment of ...
  http://jpet.aspetjournals.org/content/early/2005/12/28/jpet.105.095687
*  Blood pressure-independent renoprotection in diabetic rats treated with AT1 receptor-neprilysin inhibition versus AT1 receptor...
Dual angiotensin II type 1 (AT1;) receptor-neprilysin inhibition (ARNI) exerts beneficial effects on blood pressure (BP) and ... Blood pressure-independent renoprotection in diabetic rats treated with AT1 receptor-neprilysin inhibition versus AT1 receptor ... Blood pressure-independent renoprotection in diabetic rats treated with AT1 receptor-neprilysin inhibition versus AT1 receptor ... Blood pressure-independent renoprotection in diabetic rats treated with AT1 receptor-neprilysin inhibition versus AT1 receptor ...
  http://www.clinsci.org/content/early/2016/04/19/CS20160197
*  Microbiology Society Journals | No influence of amyloid-β-degrading neprilysin activity on prion pathogenesis
As neprilysin has a broad substrate specificity and is localized subcellularly in the vicinity of PrP, it represents a ... However, the gene dosage of neprilysin did not modulate accumulation of PrPSc in brain. Also, incubation times and clinical ... Here, it was investigated whether neprilysin, a metalloprotease known to degrade extracellular amyloidogenic proteins such as ... These data rule out neprilysin as a major modulator of PrPSc accumulation and prion pathogenesis. ...
  http://jgv.microbiologyresearch.org/content/journal/jgv/10.1099/vir.0.80811-0
*  Angiotensin receptor neprilysin inhibitor LCZ696: Pharmacology, pharmacokinetics and clinical development
Angiotensin receptor neprilysin inhibitors are a new class drug capable of blocking the renin-angiotensin-aldosterone system ... Angiotensin receptor neprilysin inhibitor LCZ696: Pharmacology, pharmacokinetics and clinical development. Future Cardiology. ...
  https://espace.curtin.edu.au/handle/20.500.11937/51401
*  Localization of neprilysin (EC 3.4.24.11) mRNA in rat brain by in situ hybridization.
... coding for neprilysin (EC 3.4.24.11) has been studied by in situ hybridization in the adult rat brain. A markedly heterogenous ... Localization of neprilysin (EC 3.4.24.11) mRNA in rat brain by in situ hybridization. Gaudoux, F 관련메뉴. ; Boileau, G 관련메뉴. ; ... which show a high or a moderate amount of neprilysin, did not contain any neprilysin mRNA. Comparison of the regional ... The distribution of the messenger RNA (mRNA) coding for neprilysin (EC 3.4.24.11) has been studied by in situ hybridization in ...
  http://www.ndsl.kr/ndsl/search/detail/article/articleSearchResultDetail.do?cn=NART00108024
*  Interpretation of B-type natriuretic peptides in the era of angiotensin receptor-neprilysin inhibitors
Following the recent advent of angiotensin receptor-neprilysin inhibitors (ARNIs), there is a need to review how these two ... Interpretation of B-type natriuretic peptides in the era of angiotensin receptor-neprilysin inhibitors ... Interpretation of B-type natriuretic peptides in the era of angiotensin receptor-neprilysin inhibitors ...
  http://www.elsevier.pt/en/revistas/revista-portuguesa-cardiologia-english-edition--434/artigo-resumo/interpretation-b-type-natriuretic-peptides-in-era-angiotensin-receptor-neprilysin-S2174204917303318
*  Entresto (Sacubitril/Valsartan): First-in-Class Angiotensin Receptor Neprilysin Inhibitor FDA Approved for Patients with Heart...
Sacubitril is a neprilysin inhibitor and valsartan is an angiotensin receptor blocker.11 The combination of sacubitril plus ... Angiotensin receptor-neprilysin inhibition with LCZ696: a novel approach for the treatment of heart failure. Drug Discov Today ... Angiotensin-neprilysin inhibition versus enalapril in heart failure. N Engl J Med. 2014;371:993-1004. ... The first-in-class angiotensin receptor neprilysin inhibitor sacubitril plus valsartan demonstrated a significant mortality ...
  http://insidepatientcare.com/issues/2015/october-2015-vol-3-no-10/271-entresto-sacubitril-valsartan-first-in-class-angiotensin-receptor-neprilysin-inhibitor-fda-approved-for-patients-with-heart-failure
*  Qbrelis - FDA prescribing information, side effects and uses
Neprilysin Inhibitor. Patients taking concomitant neprilysin inhibitors may be at increased risk for angioedema [see Warnings ... Qbrelis is contraindicated in combination with a neprilysin inhibitor (e.g., sacubitril). Do not administer Qbrelis within 36 ... therapy or a neprilysin inhibitor may be at increased risk for angioedema [see Drug Interactions (7.7, 7.8)]. ... hours of switching to or from sacubitril/valsartan, a neprilysin inhibitor [see Warnings and Precautions (5.2)]. ...
  https://www.drugs.com/pro/qbrelis.html
*  Treatment Advances for Patients With Heart Failure | HealthCentral
Neprilysin inhibitors promote enzymes in the body that remove sodium and relax blood vessels; they appear to reduce CHF ... In 2017, the guidelines were updated to include a new treatment class: neprilysin inhibitors. The first of this class to be ...
  http://www.healthcentral.com/slideshow/treatment-advances-for-patients-with-heart-failure
*  Current Issue : American Journal of Therapeutics
Role of Neprilysin Inhibitors in Heart Failure. Salazar Adum, Juan P.; Arora, Rohit ...
  http://journals.lww.com/americantherapeutics/pages/currenttoc.aspx
*  Peptides and Proteins: Novus Biologicals
Neprilysin-2 / MMEL1 (3). *. PDHX (3). *. PIN4 (3). *. Phosducin (1). *. Pyruvate Dehydrogenase E2 (2) ...
  https://www.novusbio.com/product-type/peptides-and-proteins?related_diseases=Primary%20Biliary%20Cirrhosis
*  Cathepsin D - Wikipedia
The NCLs present with progressive loss of visual function and neurodevelopmental decline, seizure, myoclonic jerks and premature death. The CTSD gene is one of the identified eight genes the deficiency of which is responsible for NCLs.[10] It has been reported that a homozygous single nucleotide duplication in exon 6 could alter the reading frame and causes a premature stop codon at position 255. Over-expression of cathepsin D stimulates tumorigenicity and metastasis as well as initiation of tumor apoptosis. This protease has been regarded an independent marker of poor prognosis in breast cancer being correlated with the incidence of clinical metastasis.[21][22] Knock-out of CTSD gene would cause intestinal necrosis and hemorrhage and increase apoptosis in thymus, indicating that cathepsin D is required in certain epithelial cells for tissue remodeling and renewal.[9] It is also reported that there might be a strong effect for CTSD genotype on Alzheimer disease risk in male.[23] Cathepsin D ...
  https://en.wikipedia.org/wiki/Cathepsin_D
*  Desmin - Wikipedia
Desmin was first described in 1976,[15] first purified in 1977,[16] the gene was cloned in 1989,[6] and the first knockout mouse was created in 1996.[17] The function of desmin has been deduced through studies in knockout mice. Desmin is one of the earliest protein markers for muscle tissue in embryogenesis as it is detected in the somites.[11] Although it is present early in the development of muscle cells, it is only expressed at low levels, and increases as the cell nears terminal differentiation. A similar protein, vimentin, is present in higher amounts during embryogenesis while desmin is present in higher amounts after differentiation. This suggests that there may be some interaction between the two in determining muscle cell differentiation. However desmin knockout mice develop normally and only experience defects later in life.[12] Since desmin is expressed at a low level during differentiation another protein may be able to compensate for desmin's function early in development but not ...
  https://en.wikipedia.org/wiki/Desmin