*  Abstract 5504: Second neoplasms after childhood cancer and gene expression differences in primary fibroblasts | Cancer Research
We used false discovery rate control by explorative Simes procedure to account for multiple testing. Additionally, we used ... Treatment of the primary neoplasm with radiotherapy or chemotherapy is an established risk factor for second neoplasms (SNs) ... Abstract 5504: Second neoplasms after childhood cancer and gene expression differences in primary fibroblasts. Manuela Marron, ... Abstract 5504: Second neoplasms after childhood cancer and gene expression differences in primary fibroblasts ...
  http://cancerres.aacrjournals.org/content/72/8_Supplement/5504
*  A Study of Two Vismodegib Regimens in Participants With Multiple Basal Cell Carcinomas - Full Text View - ClinicalTrials.gov
Hamartoma Syndrome, Multiple. Neoplasms, Glandular and Epithelial. Neoplasms by Histologic Type. Neoplasms. Neoplasms, Basal ... Primary Purpose:. Treatment. Official Title:. A Randomized, Double-blinded, Regimen-controlled, Phase II, Multicenter Study to ... A Study of Two Vismodegib Regimens in Participants With Multiple Basal Cell Carcinomas. The safety and scientific validity of ... Primary Outcome Measures : *Mean Percent Change From Baseline in the Number of Clinically Evident Basal Cell Carcinomas at Week ...
  https://clinicaltrials.gov/ct2/show/NCT01815840?recr=Open&cond=%22Carcinoma%2C+Basal+Cell%22&rank=16
*  Rapamycin In Angiomyolipomas In Patients With Tuberous Sclerosis - Full Text View - ClinicalTrials.gov
Neoplasms. Neoplasms, Multiple Primary. Neoplastic Syndromes, Hereditary. Malformations of Cortical Development, Group I. ... Neoplasms, Adipose Tissue. Neoplasms, Connective and Soft Tissue. Neoplasms by Histologic Type. Perivascular Epithelioid Cell ... Primary Completion Date:. May 2011 (Final data collection date for primary outcome measure). ... Primary Purpose: Treatment. Official Title:. CLINICAL TRIAL TO DETERMINE THE EFFICACY AND SAFETY OF RAPAMYCIN IN ...
  https://clinicaltrials.gov/ct2/show/NCT01217125
*  Rapamycin Therapy for Patients With Tuberous Sclerosis Complex and Sporadic LAM - Full Text View - ClinicalTrials.gov
Neoplasms. Neoplasms, Multiple Primary. Neoplastic Syndromes, Hereditary. Malformations of Cortical Development, Group I. ... Neoplasms by Histologic Type. Perivascular Epithelioid Cell Neoplasms. Neoplasms, Connective and Soft Tissue. ... Primary Purpose: Treatment. Official Title:. Rapamycin Therapy of Angiomyolipomas in Patients With Tuberous Sclerosis Complex ...
  https://clinicaltrials.gov/ct2/show/NCT00457808?term=Tuberous+Sclerosis&rank=5
*  A Placebo-controlled Study of Efficacy & Safety of 2 Trough-ranges of Everolimus as Adjunctive Therapy in Patients With...
Neoplasms. Neoplasms, Multiple Primary. Neoplastic Syndromes, Hereditary. Malformations of Cortical Development, Group I. ... Primary Purpose:. Treatment. Official Title:. A Three-arm, Randomized, Double-blind, Placebo-controlled Study of the Efficacy ... Primary Outcome Measures : *European Medicine Agency (EMA): Response rate [ Time Frame: Baseline, Week 12 ]. Response means at ...
  https://clinicaltrials.gov/ct2/show/NCT01713946?recr=Open&cond=%22Tuberous+Sclerosis%22&rank=6
*  Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis...
Neoplasms. Neoplasms, Multiple Primary. Neoplastic Syndromes, Hereditary. Malformations of Cortical Development, Group I. ... Neoplasms by Histologic Type. Perivascular Epithelioid Cell Neoplasms. Neoplasms, Connective and Soft Tissue. ... Primary Purpose:. Treatment. Official Title:. A Randomized, Double-blind, Placebo-controlled Study of RAD0001 in the Treatment ... Primary Outcome Measures : *Angiomyolipoma Response Rate as Per Central Radiology Review [ Time Frame: From date of ...
  https://clinicaltrials.gov/ct2/show/NCT00790400?term=Tuberous+Sclerosis&rank=13
*  Potential EEG Biomarkers and Antiepileptogenic Strategies for Epilepsy in TSC - Full Text View - ClinicalTrials.gov
Neoplasms. Neoplasms, Multiple Primary. Neoplastic Syndromes, Hereditary. Malformations of Cortical Development, Group I. ... Primary Outcome Measures : *Identification of EEG biomarkers as predictors of developing epilepsy in infants with Tuberous ...
  https://clinicaltrials.gov/ct2/show/NCT01767779?term=Infantile+Spasms&rank=15
*  Early Biomarkers of Autism in Infants With Tuberous Sclerosis Complex (TSC) - Full Text View - ClinicalTrials.gov
Neoplasms. Neoplasms, Multiple Primary. Neoplastic Syndromes, Hereditary. Malformations of Cortical Development, Group I. ... Estimated Primary Completion Date:. February 2019 (Final data collection date for primary outcome measure). ... Primary Outcome Measures: *ADOS evaluation score at the 36 month visit [ Time Frame: 36 months ]. The ADOS performed at 24 and ... The primary outcome is the possible clinical diagnosis of autism spectrum disorder per the DSM 5 guidelines (Autistic Disorder ...
  https://clinicaltrials.gov/ct2/show/study/NCT01780441?view=results
*  Trial of RAD001 and Neurocognition in Tuberous Sclerosis Complex (TSC) - Full Text View - ClinicalTrials.gov
Neoplasms. Neoplasms, Multiple Primary. Neoplastic Syndromes, Hereditary. Malformations of Cortical Development, Group I. ... Primary Completion Date:. December 2014 (Final data collection date for primary outcome measure). ... Primary Purpose: Treatment. Official Title:. Randomized Double-Blind Phase 2 Trial Of RAD001 For Neurocognition In Individuals ... Primary Outcome Measures: *Evaluate the safety of RAD001 on neurocognition in patients with TSC compared with placebo in ...
  https://clinicaltrials.gov/ct2/show/NCT01289912
*  Tuberous Sclerosis Complex Natural History Study: Renal Manifestations - Full Text View - ClinicalTrials.gov
Neoplasms. Neoplasms, Multiple Primary. Neoplastic Syndromes, Hereditary. Malformations of Cortical Development, Group I. ... Primary Completion Date:. September 2013 (Final data collection date for primary outcome measure). ...
  https://clinicaltrials.gov/ct2/show/NCT00598455?term=Tuberous+Sclerosis&rank=6
*  Study of Skin Tumors in Tuberous Sclerosis - Full Text View - ClinicalTrials.gov
Neoplasms. Neoplastic Syndromes, Hereditary. Pathologic Processes. Hamartoma. Neoplasms, Multiple Primary. Malformations of ... Tuberous sclerosis is a rare, hereditary disease in which patients develop multiple tumors. Although not cancerous, the tumors ... The minor features of TSC are: multiple randomly distributed pits in dental enamel, hamartomatous rectal polyps, bone cysts, ... Patients with tuberous sclerosis develop benign cutaneous tumors that are typically multiple in number and location. These ...
  https://clinicaltrials.gov/ct2/show/NCT00001975?recr=Open&cond=%22Tuberous+Sclerosis%22&rank=1
*  Studies of Inherited Diseases of Metabolism - Full Text View - ClinicalTrials.gov
Neoplasms by Site. Neoplasms, Multiple Primary. Neoplastic Syndromes, Hereditary. Genetic Diseases, Inborn. ... Multiple Endocrine Neoplasia. Neoplasms. Hyperparathyroidism. Hypercalcemia. Endocrine Gland Neoplasms. Parathyroid Diseases. ... Familial multiple endocrine neoplasia type 1 (MEN1), familial hypocalciuric (or familial benign) hypercalcemia (FHH), ... FHH is characterized by a usually benign syndrome sometimes mistaken for typical primary hyperparathyroidism, which may result ...
  https://clinicaltrials.gov/ct2/show/NCT00001345?recr=Open&cond=%22Multiple+Endocrine+Neoplasia%22&rank=3
*  Trial Comparing the Effects of Intermittent Vismodegib vs. PDT in Patients With Multiple Basal Cell Carcinomas - Full Text View...
Abnormalities, Multiple. Congenital Abnormalities. Genetic Diseases, Inborn. Hamartoma. Neoplasms, Multiple Primary. ... Neoplasms, Glandular and Epithelial. Neoplasms by Histologic Type. Neoplasms. Neoplasms, Basal Cell. Odontogenic Cysts. Jaw ... Primary Purpose:. Treatment. Official Title:. A Phase II Randomized, Open Label Trial Comparing the Effects of Intermittent ... PDT in Patients With Multiple Basal Cell Carcinomas (Vismodegib). The safety and scientific validity of this study is the ...
  https://clinicaltrials.gov/ct2/show/NCT01556009?recr=Open&cond=%22Jaw+Diseases%22&rank=4
*  A Phase I/II Study of BEZ235 in Patients With Advanced Solid Malignancies Enriched by Patients With Advanced Breast Cancer -...
Neoplasms by Site. Neoplasms. Breast Diseases. Skin Diseases. Hamartoma. Neoplasms, Multiple Primary. Neoplastic Syndromes, ... Neoplasms. breast neoplasms. breast diseases. solid tumors. BEZ235. breast cancer. PI3K Inhibitor. Phosphatidylinositol 3. ... Primary Completion Date:. January 8, 2013 (Final data collection date for primary outcome measure). ... Primary Purpose: Treatment. Official Title:. A Phase I/II, Multi-center, Open-label Study of BEZ235, Administered Orally on a ...
  https://clinicaltrials.gov/show/NCT00620594
*  Doxycycline In Lymphangioleiomyomatosis (LAM) - Full Text View - ClinicalTrials.gov
Neoplasms. Neoplasms, Multiple Primary. Neoplastic Syndromes, Hereditary. Malformations of Cortical Development, Group I. ... Neoplasms by Histologic Type. Perivascular Epithelioid Cell Neoplasms. Neoplasms, Connective and Soft Tissue. ... Primary Outcome Measures : *Mean rate of change of FEV1 over 24 months on doxycycline compared with placebo. [ Time Frame: 2 ... Primary Purpose:. Treatment. Official Title:. A Randomised, Double Blind, Placebo Controlled Trial of Doxycycline in ...
  https://clinicaltrials.gov/ct2/show/NCT00989742
*  Trial of Efficacy and Safety of Sirolimus in Tuberous Sclerosis and LAM - Full Text View - ClinicalTrials.gov
Neoplasms. Neoplasms, Multiple Primary. Neoplastic Syndromes, Hereditary. Malformations of Cortical Development, Group I. ... Neoplasms by Histologic Type. Perivascular Epithelioid Cell Neoplasms. Neoplasms, Connective and Soft Tissue. ... Estimated Primary Completion Date:. September 2009 (Final data collection date for primary outcome measure). ... Primary Purpose: Treatment. Official Title:. A Trial of the Efficacy and Safety of Sirolimus(Rapamycin)Therapy for Renal ...
  https://clinicaltrials.gov/ct2/show/NCT00490789?term=Tuberous+Sclerosis&rank=13
*  Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex (TSC) - Full Text View - ClinicalTrials.gov
Neoplasms. Neoplasms, Multiple Primary. Neoplastic Syndromes, Hereditary. Malformations of Cortical Development, Group I. ... This disorder is characterized by the development of benign tumors in multiple organ systems, including the brain. The primary ... Primary Outcome Measures : *Reduction in Seizure Frequency [ Time Frame: Baseline (Weeks 1-4), Week 16 ]. The primary efficacy ... Primary Purpose:. Treatment. Official Title:. Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis ...
  https://clinicaltrials.gov/ct2/show/NCT01070316?term=Tuberous+Sclerosis&rank=12
*  Benign mesenchymal tumours and tumour-like lesions in end-stage renal disease.
Mesenchymal neoplasms of the kidney are rare, and most represent sporadic angiomyolipomas. A few haemangiomas have been ... Neoplasms, Multiple Primary. Nephrectomy. Receptors, Cytoplasmic and Nuclear / metabolism. Retrospective Studies. Tumor Markers ... AIMS: Mesenchymal neoplasms of the kidney are rare, and most represent sporadic angiomyolipomas. A few haemangiomas have been ... Kidney Neoplasms / complications, metabolism, pathology*. Male. Microfilament Proteins / metabolism. Middle Aged. ...
  http://www.biomedsearch.com/nih/Benign-mesenchymal-tumours-tumour-like/23020314.html
*  Genetic Evaluation of Families With Endocrine Cancers - Full Text View - ClinicalTrials.gov
Thoracic Neoplasms. Lymphatic Diseases. Multiple Endocrine Neoplasia. Neoplasms, Multiple Primary. Neoplastic Syndromes, ... Thymus Neoplasms. Endocrine Gland Neoplasms. Multiple Endocrine Neoplasia Type 1. Digestive System Neoplasms. Neoplasms by Site ... 5) Multiple endocrine neoplasia type 1 (MEN1) germline mutations in familial isolated primary hyperparathyroidism. Pannett AA, ... Primary Completion Date:. September 2015 (Final data collection date for primary outcome measure). ...
  https://clinicaltrials.gov/show/NCT01794676
*  WikiGenes - PRSS38 - protease, serine, 38
Clinical aspects of multiple primary neoplasms. Robinson, E., Neugut, A.I. Cancer Detect. Prev. (1989) [Pubmed] ... Optimal treatment for the first primary neoplasm should be given, but the possible risk of MPN should be taken into ... the one that is less carcinogenic and that will allow appropriate therapy for a second primary neoplasm (MPN2) should be chosen ...
  https://www.wikigenes.org/e/gene/e/339501.html
*  Pazopanib Hydrochloride in Treating Patients With Advanced Neuroendocrine Cancer - Full Text View - ClinicalTrials.gov
Neoplasms by Site. Digestive System Diseases. Pancreatic Diseases. Endocrine System Diseases. Neoplasms, Multiple Primary. ... Multiple Endocrine Neoplasia Type 1. Somatostatinoma. Gastrinoma. Neoplasms, Glandular and Epithelial. Neoplasms by Histologic ... Multiple Endocrine Neoplasia. Endocrine Gland Neoplasms. Glucagonoma. Malignant Carcinoid Syndrome. Gastrointestinal Neoplasms ... Neoplasms, Germ Cell and Embryonal. Neoplasms, Nerve Tissue. Adenocarcinoma. Adenoma, Islet Cell. Adenoma. Pancreatic Neoplasms ...
  https://clinicaltrials.gov/ct2/show/NCT00454363?recr=Open&cond=%22Carcinoma%2C+Islet+Cell%22&rank=5
*  basal cell adenoma morphologic abnormality 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Neoplasms, Multiple Primary / pathology. Parotid Neoplasms / pathology. Skin Neoplasms / pathology. *[MeSH-minor] Biopsy, Fine- ... Neoplasms, Multiple Primary / pathology. Parotid Neoplasms / pathology. *[Email] Email this result item Email the results to ... Neoplasms, Multiple Primary / pathology. Parotid Neoplasms / pathology. *[MeSH-minor] Adenolymphoma / diagnosis. Aged. ... Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Neoplasm ...
  http://www.bmlsearch.com/?kwr=basal+cell+adenoma+morphologic+abnormality+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
*  basaloid skin squamous cell carcinoma 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Neoplasms, Multiple Primary. *Genetic Alliance. consumer health - Carcinoma, Squamous Cell.. *MedlinePlus Health Information. ... Lip Neoplasms / pathology. Mandibular Neoplasms / pathology. Skin Neoplasms / pathology. *[MeSH-minor] Aged. Carcinoembryonic ... Neoplasm Invasiveness. Neoplasm Recurrence, Local / pathology. Neoplasms, Basal Cell / pathology. *Genetic Alliance. consumer ... Facial Neoplasms / pathology. Skin Neoplasms / pathology. *[MeSH-minor] Aged. Carcinoma, Squamous Cell / pathology. Diagnosis, ...
  http://www.bmlsearch.com/?kwr=basaloid+skin+squamous+cell+carcinoma+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0