Cache Valley virus - Wikipedia
... whose genome is composed of three single-stranded, negative-sense RNA segments. The large segment of related bunyaviruses is ... and Hawaii for antibodies to Cache Valley and antigenically related viruses (Bunyamwera serogroup virus). The American Journal ... Bunyamwera virus (BUNV) codes for two non-structural proteins: NSm on the medium RNA segment and NSs on the smallest RNA ... a teratogenic virus of the Orthobunyavirus genus closely related to Cache Valley Virus, the virus was shown to replicate in the ...https://en.wikipedia.org/wiki/Cache_Valley_virus
Maguari virus - Wikipedia
... is a negative-sense, single-stranded RNA virus in the Bunyavirales order, genus Orthobunyavirus, Bunyamwera serogroup, that has ... that Tensaw virus subtypes stimulate the production of antibodies reactive with closely related Bunyamwera serogroup viruses. ... Bunyamwera serogroup virus may exist in south Florida. U.S. Centers for Disease Control and Prevention: "Virus Name: Maguari" ... MAGV is related to Cache Valley virus and Tensaw virus. In addition to humans, MAGV has been isolated from mosquitoes, horses, ...https://en.wikipedia.org/wiki/Maguari_virus
Bunyamwera virus - Wikipedia
... which are a family of enveloped negative-sense single stranded RNA viruses with a genome split into three parts-Small (S), ... The Bunyamwera virus (BUNV) is a negative-sense single stranded enveloped RNA virus. It is the type species of the ... Reassortant viruses derived from Bunyamwera virus, such as Ngari virus, which has been associated with large outbreaks of viral ... Middle (M) and Large (L). The L RNA segment encodes an RNA-dependent RNA polymerase (L protein), the M RNA segment encodes two ...https://en.wikipedia.org/wiki/Bunyamwera_virus
Negative-sense single-stranded RNA virus - Wikipedia
... a Family of segmented NSVs that includes the Bunyamwera virus and the Schmallenberg virus) show that in these viruses the ... A negative-sense single-stranded RNA virus (or (-)ssRNA virus) is a virus that uses negative sense, single-stranded RNA as its ... Positive-sense single-stranded RNA virus Double-stranded RNA virus Baltimore classification Sense (molecular biology) Baltimore ... which is unique to the varying classifications of negative-sense single-stranded RNA viruses. Negative sense ssRNA viruses need ...https://en.wikipedia.org/wiki/Negative-sense_single-stranded_RNA_virus
bunyavirus: Topics by WorldWideScience.org
... a negative-strand RNA virus-severe fever with thrombocytopenia syndrome bunyavirus, and a positive-strand RNA virus-dengue ... is the prototype of both the Orthobunyavirus genus and the Bunyaviridae family of segmented negative sense RNA viruses. The ... single-strand cDNA, double-strand cDNA, double-strand cDNA treated with ligation without or with supplemental RNA were ... One strain of Dugbe virus was originated from the brain of Cercopithecus patas. Bunyamwera and Abadina viruses were isolated ...https://worldwidescience.org/topicpages/b/bunyavirus.html
Batai virus - Wikipedia
Classified via the Baltimore scheme, Batai virus is a negative-sense, single-stranded RNA virus. The orthobunyavirus genome has ... Associated viruses include Crimean-Congo hemorrhagic fever, Bunyamwera fever, and severe fever with thrombocytopenia syndrome. ... Batai virus (BATV) is an enveloped, single-stranded, negative sense RNA genome. It is a member of the genus Orthobunyavirus and ... A closely associated disease is the Bunyamwera virus, which is of the same family and genus as the Batai virus (BATV); it is ...https://en.wikipedia.org/wiki/Batai_virus
Bunyamwera bunyavirus RNA synthesis requires cooperation of 3'- and 5'-terminal sequences. - Semantic Scholar
As for all negative-sense RNA viruses, the 3'- and 5'-terminal nontranslated regions (NTRs) of the BUNV S, M, and L segments ... a single mRNA and are replicated to generate an antigenome that acts as a template for synthesis of further genomic strands. ... is the prototype of both the Orthobunyavirus genus and the Bunyaviridae family of segmented negative-sense RNA viruses. The ... We show that cooperation between 3'- and 5'-NTR sequences is required for BUNV RNA synthesis, and our results suggest that this ...https://www.semanticscholar.org/paper/Bunyamwera-bunyavirus-RNA-synthesis-requires-of-3%27-Barr-Wertz/e50f3c4e2aecdff75c8f20947b1720cce3141d4f
Free Virology Books Download | Ebooks Online Textbooks Tutorials
Negative sense single stranded RNA viruses, Morbilli virus, Orthomyxo viruses, Equine flu, nature of the virus, disease and its ... This note displays 22 virus images such as Vertebrate virus families such as Bunyamwera virus, Coronaviruses, Ebola virus, ... Virus host interaction, Positive strand RNA virus, Negative strand RNA viruses, Other RNA viruses and DNA viruses.. ... LaCrosse virus, Lassa virus, Marburg Virus, Poliovirus, Rabies virus, Rift Valley fever virus, Ross River virus, Scrapie, Sin ...http://freebookcentre.net/Biology/Virology-Books.html
Bunyavirales - Wikipedia
e Bunyavirales is an order of negative-sense single-stranded RNA viruses. It was formerly known as Bunyaviridae family of ... Bunyamwera virus Family Phenuiviridae (which contains former genus Phlebovirus; type species: Rift Valley fever virus Family ... the so-called negative-sense single stranded ribonucleic acid (−)ssRNA. They are enveloped RNA viruses. Though generally found ... Ambisense means that some of the genes on the RNA strand are negative sense and others are positive sense. The S segment codes ...https://en.wikipedia.org/wiki/Bunyavirales
Arthropod-Borne and Rodent-Borne Viral Diseases | Jawetz, Melnick, & Adelberg's Medical Microbiology, 27e | AccessMedicine |...
Genome: triple-segmented, negative-sense or ambisense, single-stranded RNA, 11-19 kb in total size. Virion contains a ... Heartland virus, Lone Star virus, Rift Valley fever virus, sandfly (Phlebotomus) fever viruses, severe fever with ... Anopheles A and B, Bunyamwera, California encephalitis, Guama, La Crosse, Oropouche, and Turlock viruses. Arthropod borne ( ... Genome: negative-sense, nonsegmented, single-stranded RNA, 19 kb in size. Seven polypeptides. Envelope. Replication: cytoplasm ...http://accessmedicine.mhmedical.com/content.aspx?bookid=1551§ionid=94110315
Herpes simplex virus 1 infection dampens the immediate early antiviral innate immunity signaling from peroxisomes by tegument...
However, little is known about the interaction between DNA viruses such as HSV-1 and the MAVS-Pex mediated signaling. HSV-1 ... Moreover, the expression of ISGs was recovered when VP16 was knockdown with its specific short hairpin RNA. HSV-1 blocks MAVS- ... many of which play a critical role in virus-host interactions and immune modulation. Upon viral infections, the host cells ... Herpes simplex virus 1 (HSV-1) is an archetypal member of the alphaherpesvirus subfamily with a large genome encoding over 80 ...https://virologyj.biomedcentral.com/articles/10.1186/s12985-017-0709-5
Interferon-Stimulated Gene (ISG)-Expression Screening Reveals the Specific Antibunyaviral Activity of ISG20 | Journal of...
... single-stranded, negative-sense RNA genome. To investigate whether ISG20 targets a specific genome segment or all three ... The Bunyamwera virus nonstructural protein NSs inhibits viral RNA synthesis in a minireplicon system. Virology 281:67-74. doi: ... RIG-I-like receptors and negative-strand RNA viruses: RLRly bird catches some worms. Cytokine Growth Factor Rev 25:621-628. doi ... Kairi virus (KRIV), Anopheles A virus (ANAV), Tacaiuma virus (TCMV), Boraceia virus (BORV), Capim virus (CAPV), Oropouche virus ...https://jvi.asm.org/content/92/13/e02140-17
Rift Valley fever virus NSs protein functions and the similarity to other bunyavirus NSs proteins | Virology Journal | Full Text
The nonstructural (NS) protein, which is a major virulence factor for Rift Valley fever virus (RVFV), is encoded on the S- ... The bunyavirus genome is comprised of three negative-sense single stranded RNA segments; Large (L)-, Medium (M)-, and Small (S ... This cap-snatching mechanism is also commonly used in other segmented negative-stranded RNA viruses (e.g., influenza viruses, ... The Bunyamwera virus nonstructural protein NSs inhibits viral RNA synthesis in a minireplicon system. Virology. 2001;281:67-74. ...https://virologyj.biomedcentral.com/articles/10.1186/s12985-016-0573-8
Lassa virus - Wikipedia
One of the mechanisms detects double stranded RNA (dsRNA), which is only synthesized by negative-sense viruses. In the ... Lassa viruses are enveloped, single-stranded, bisegmented, ambisense RNA viruses. Their genome is contained in two ... Tahyna virus (TAHV). *Viral hemorrhagic fevers: Rift Valley fever *RVFV. *Bunyamwera fever (BUNV) ... then makes viral complementary RNA (vcRNA) copies of itself. The RNA copies are a template for producing negative-sense progeny ...https://en.wikipedia.org/wiki/Lassa_virus
Tula hantavirus isolate with the full-length ORF for nonstructural protein NSs survives for more consequent passages in...
Our data show that expression of a full-length NSs protein is beneficial for the virus survival and competitiveness in IFN- ... The genome of hantaviruses consists of three segments of a negative-sense single-stranded RNA. The large (L) segment codes for ... Titration of viruses. Confluent Vero E6 cells grown on 6-well plate wells were infected with several virus dilutions (0.5 ml) ... Léonard VH, Kohl A, Hart TJ, Elliott RM: Interaction of Bunyamwera Orthobunyavirus NSs protein with mediator protein MED8: a ...https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-5-3
Bunyaviridae | definition of Bunyaviridae by Medical dictionary
... a family of RNA viruses whose genome comprises three molecules of circular negative-sense single-stranded RNA; it includes the ... bunyamwera virus. *Bunyamwera virus infection. *Bunyaviridae. *bunyavirus. *bunyavirus encephalitis. *Bunyavirus germiston ... Virology A family of single-stranded RNA enveloped arboviruses composed of , 200 viruses, including genera Bunyavirus, ... A family of single-stranded RNA-enveloped arboviruses, which are spherical to oval in shape, measure 90-100 nm in diameter and ...http://medical-dictionary.thefreedictionary.com/Bunyaviridae
JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... negative-sense, single-stranded, enveloped RNA virus (Figure 1) with potential applications as a vector for vaccination and ... Three of these viruses (West Nile virus, Potosi virus, and La Crosse virus) represent new records for North America or the New ... Typical results are presented for Bunyamwera virus, an enveloped virus from the family Bunyaviridae. This family is a ... RNA viruses use RNA dependent RNA polymerases to replicate their genomes. The intrinsically high error rate of these enzymes is ...https://www.jove.com/visualize/abstract/21390296/synthetic-protocells-interact-with-viral-nanomachinery-inactivate
US Patent # 9,566,348. Methods and compositions for the treatment of cancer and infectious disease using alpha(2)...
Infectious virus of both human and non-human vertebrates, include retroviruses, RNA viruses and DNA viruses. Examples of virus ... sense oligonucleotides; signal transduction inhibitors; signal transduction modulators; single chain antigen binding protein; ... Bunyamwera and related viruses, California encephalitis group viruses), the genus Phlebovirus (Sandfly fever Sicilian virus, ... as a negative control, called PBS1: 8) serum of mice immunized with PBS as a negative control, called PBS2; 9) serum of mice ...http://patents.com/us-9566348.html
Marburg virus disease - Wikipedia
Like all monomegaviruses, marburgvirions contain non-infectious, linear nonsegmented, single-stranded RNA genomes of negative ... "Rapid Detection and Quantification of RNA of Ebola and Marburg Viruses, Lassa Virus, Crimean-Congo Hemorrhagic Fever Virus, ... Photogrammetric Engineering and Remote Sensing. 68 (2): 144-52.. ... Bunyamwera fever (BUNV). *Ngari virus (NRIV). Flaviviridae. * ... Replication results in full-length, positive-stranded antigenomes that are in turn transcribed into negative-stranded virus ...https://en.wikipedia.org/wiki/Marburg_
Living With Mesothelioma-My Diary- A summers day., A nice Artical about Richard Elliott, Flying and dangerous fumes,BBC1 DIY...
He was indeed the first to develop a cDNA infectious clone for a SEGMENTED negative-sense RNA virus, Bunyamwera virus. ... It proved very difficult to make infectious DNAs of negative strand RNA viruses, and it was Richard who was the first to ... Asbestos is the single greatest cause of work related deaths in the UK. On average 20 tradesmen die per week from asbestos ... In addition, reverse-genetics systems several other negative-sense viruses including VSV, Sendai virus, measles virus, and RSV ...https://rayandmave.wordpress.com/2015/06/18/living-with-mesothelioma-my-diary-a-summers-day-a-nice-artical-about-richard-elliott-flying-and-dangerous-fumesbbc1-diy-sos-do-care-about-asbestos/
VIRUSES ENCODING MUTANT MEMBRANE PROTEIN - Patent application
Influenza Virus Influenza A viruses possess a genome of eight single-stranded negative-sense viral RNAs (vRNAs) that ... Bunyamwera virus (Bunyaviridae family), but it contains only three segments of negative-sense RNA, and the efficiency of its ... negative-sense RNA viruses. Plasmids containing the RNA polymerase I promoter a cDNA for each of the eight viral RNA segments, ... 0004]The influenza A virus is an enveloped negative-strand virus with eight RNA segments encapsidated with nucleoprotein (NP) ( ...http://www.patentsencyclopedia.com/app/20100247572
JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
... negative-sense, single-stranded, enveloped RNA virus (Figure 1) with potential applications as a vector for vaccination and ... respiratory syncytial virus (RSV), Ebola virus, influenza virus, as well as Nipah and Handra viruses. In addition, the methods ... Typical results are presented for Bunyamwera virus, an enveloped virus from the family Bunyaviridae. This family is a ... Hepatitis C virus (HCV) is a hepatotropic virus with a host-range restricted to humans and chimpanzees. Although HCV RNA ...https://www.jove.com/visualize/abstract/23185364/ezrin-interacts-with-sars-coronavirus-spike-protein-restrains
Generation of recombinant lymphocytic choriomeningitis viruses with trisegmented genomes stably expressing two additional genes...
Arenaviruses have a bisegmented negative-strand RNA genome. The S segment encodes for the virus nucleoprotein and glycoprotein ... Our results would suggest that unlike the influenza virus (29 and references therein) but similar to bunyamwera virus (30), ... Use of Single-Cycle Infectious Lymphocytic Choriomeningitis Virus To Study Hemorrhagic Fever Arenaviruses ... Human Plasmacytoid Dendritic Cells Sense Lymphocytic Choriomeningitis Virus-Infected Cells In Vitro ...http://www.pnas.org/content/106/9/3473.long
Substitution of the premembrane and envelope protein genes of Modoc virus with the homologous sequences of West Nile virus...
Fusion products were directly transfected into baby hamster kidney-derived cells that stably express T7 RNA polymerase. At 4 ... The genetic elements that modulate the differential host ranges and transmission cycles of these viruses have not been ... Chimeric virus was recovered in cells transfected with the fusion product containing the prM-E genes of WNV. The virus could ... The in vitro replication kinetics and yields of the chimeric virus were similar to MODV but the chimeric virus produced larger ...https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-11-150