Ca2+-regulatory proteins in cardiomyocytes from the right ventricle in children with congenital heart disease | Journal of...
Ronkainen VP, Skoumal R, Tavi P: Hypoxia and HIF-1 suppress SERCA2a expression in embryonic cardiac myocytes through two ... Bers DM: Cardiac excitation-contraction coupling. Nature. 2002, 415: 198-205. 10.1038/415198a.View ArticlePubMedGoogle Scholar ... SERCA2a (the cardiac isoform of SERCA) is a Ca2+-ATPase pump in SR that pumps Ca2+ back to SR during myocardial relaxation [29 ... Subunit expression of the cardiac L-type calcium channel is differentially regulated in diastolic heart failure of the cardiac ...https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-10-67
Role of Meis1 in Regulation of Cardiomyocyte Proliferation - Hesham Sadek
Instead, lost myocytes are replaced by fibrous tissue, which results in progressive remodeling, dilatation, and further ... 2014) Surgical models for cardiac regeneration in neonatal mice. Nat Protoc 9:305-11 ... 2014) Redox signaling in cardiac renewal. Antioxid Redox Signal 21:1660-73 ...http://grantome.com/grant/NIH/R01-HL115275-02
Viability of cardiomyocytes was examined using the MTT | Open-i
Myocytes, Cardiac/metabolism/physiology*. *Oxygen/metabolism*. *Receptors, Calcium-Sensing/agonists/metabolism*. *Sarcoplasmic ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC2908572_1423-0127-17-50-2&req=4
Angiotensin II Induces Cardiac Phenotypic Modulation and Remodeling In Vivo in Rats | Hypertension
17 Fibronectin is localized along the surface of cardiac myocytes, connects cardiac myocytes to perimyocytic collagen, and is ... Cardiac sarcomeric actin is also composed of two isoforms, cardiac and skeletal α-actins.18 Cardiac α-actin is predominantly ... mechanical stretch-induced hypertrophy of cardiac myocytes is mediated by autocrine release of Ang II from cardiac myocytes,10 ... increase in cardiac myocyte size) but also by qualitative changes, including a shift to the fetal phenotype of myocytes5 12 13 ...http://hyper.ahajournals.org/content/25/6/1252?ijkey=fc355b0b00cfa7b0f95802bc159564a09f7bfc6f&keytype2=tf_ipsecsha
Mitochondrial and sarcolemmal Ca2+ transport reduce [Ca2+]i during caffeine contractures in rabbit cardiac myocytes. J Physiol ... Cardiac myocyte calcium transport in phospholamban knockout mouse: relaxation and endogenous CaMKII effects. Am J Physiol Heart ... Embryonic lethality and abnormal cardiac myocytes in mice lacking ryanodine receptor type 2. EMBO J 17: 3309-3316, 1998. ... Ascorbic acid enhances differentiation of embryonic stem cells into cardiac myocytes. Circulation 107: 1912-1916, 2003. ...http://ajpcell.physiology.org/content/297/3/C732
Downregulation of cardiac myocyte Na+-K+-ATPase by adenovirus-mediated expression of an α-subunit fragment | Heart and...
Neonatal rat cardiac myocytes were prepared and cultured as described earlier (15, 26). Myocytes were isolated from ventricles ... Downregulations of the α1- and α3-subunit mRNAs in neonatal cardiac myocytes transfected with the α2-adenovirus. Myocytes were ... and the α3-subunit proteins in neonatal cardiac myocytes transfected with the α2-adenovirus. Myocytes were transfected with the ... Downregulation of cardiac myocyte Na+-K+-ATPase by adenovirus-mediated expression of an α-subunit fragment. Peter Kometiani, ...http://ajpheart.physiology.org/content/280/3/H1415.long
Activation of Distinct cAMP-Dependent and cGMP-Dependent Pathways by Nitric Oxide in Cardiac Myocytes | Circulation Research
Cardiac Myocyte Isolation. Single cardiac myocytes were isolated via a previously described technique with minor modifications. ... Noncardiac myocytes comprised ≪1% of cells prepared in this manner. Cardiac myocyte viability was typically 70% to 80%. All ... In frog cardiac myocytes and in human atrial cells, cGMP has been shown to decrease Ca2+ influx through L-type channels by the ... Activation of Distinct cAMP-Dependent and cGMP-Dependent Pathways by Nitric Oxide in Cardiac Myocytes. Martin G. Vila-Petroff, ...http://circres.ahajournals.org/content/84/9/1020
Stable clones of HL-1 myocyte cell lines - Quicktech
Cardiac structure and functionare commonly studied using primary culture of neonatal and adult cardiac myocyte. However, their ... Established from a mouse atrial myocyte tumour, HL-1 cells share similar characteristics with primary cultures of cardiac ... Stable clones of HL-1 myocyte cell lines. Isolated homogeneous and stable clones of HL-1 cell lines ... Clones 3 and 6 appear to be most promising for cardiac research. These cells exhibit resting membrane potentials comparable to ...http://quicktech.imperialinnovations.co.uk/i/Cell_Lines/HL-1_clones.html
Poolman RA, Li JM, Durand B, Brooks G. Altered expression of cell cycle proteins and prolonged duration of cardiac myocyte ... Brooks G, Poolman RA, Li JM. Arresting developments in the cardiac myocyte cell cycle: role of cyclin-dependent kinase ... Goldman B, Mach A, Wurzel J. Epidermal growth factor promotes a cardiomyoblastic phenotype in human fetal cardiac myocytes. Exp ... Li F, Wang X, Capasso JM, Gerdes AM. Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal ...http://ajpcell.physiology.org/content/296/4/C735
Protocols and Video Articles Authored by Lijun Liu
Isolation and Culture of Adult Mouse Cardiomyocytes for Cell Signaling and in vitro Cardiac Hypertrophy', 'A Model for ... Subunits of Na(+)/K(+)-ATPase were detected by immunoblot analysis in caveolae isolated from cardiac myocytes, cardiac ... and hypertrophic growth in cardiac myocytes. 3) Unlike PP2, pNaKtide does not affect IGF-induced ERK activation in cardiac ... but not in KO myocytes. Ouabain-induced activations of ERK 1/2 were noted in Wt myocytes, but not in KO myocytes; however, ...https://www.jove.com/author/Lijun_Liu
Letter by Sluijter et al Regarding Article, "Human Cardiac Stem Cell Differentiation Is Regulated by a Mircrine Mechanism" |...
Hosoda et al also observed that Sox6 is a direct target of the myocyte-specific miR-499; moreover, via RNAi knockdown of Sox6, ... These miRNAs become highly enriched, together with miR-499, on cardiac differentiation.2 Because the c-kit-positive rat cardiac ... Human cardiac stem cell differentiation is regulated by a mircrine mechanism. Circulation. 2011;123:1287-1296. ... Letter by Sluijter et al Regarding Article, "Human Cardiac Stem Cell Differentiation Is Regulated by a Mircrine Mechanism". ...http://circ.ahajournals.org/content/124/17/e456
Intracellular calcium homeostasis in cardiac myocytes. | Circulation
Calcium homeostasis in cardiac myocytes results from the integrated function of transsarcolemmal Ca2+ influx and efflux ... It may be anticipated that a rapid increase in our understanding of the pathophysiology of Ca2+ homeostasis in cardiac myocytes ... Intracellular calcium homeostasis in cardiac myocytes.. W H Barry, J H Bridge ...http://circ.ahajournals.org/content/87/6/1806
WISDEM seminar: Signalling to gene expression in cardiac myocytes
Seminar by Professor Angela Clerk on 'Signalling to gene expression in cardiac myocytes'. ... Signalling to gene expression in cardiac myocytes'. Abstract. Cardiomyocytes, the terminally-differentiated contractile cells ...https://warwick.ac.uk/insite/events/events/wisdem_seminar_120112/
Signaling pathways in cardiac myocyte hypertrophy.
... involved in mediating cardiac myocyte hypertrophy, and has enabled the molecular dissection of the pathways involved in signal ... Previous Document: Phosphatidic acid: a potential signal transducer for cardiac hypertrophy.. Next Document: Molecular ... mechanisms of angiotensin II in modulating cardiac function: intracardiac effects and sign.... ...http://www.biomedsearch.com/nih/Signaling-pathways-in-cardiac-myocyte/9405163.html
NIOSHTIC-2 Publications Search - 00205787 - Automated surface area measurement of cultured cardiac myocytes.
An automated method measuring cardiac myocyte surface area was described and used as an index of cell growth. Hearts from 2 to ... An automated method measuring cardiac myocyte surface area was described and used as an index of cell growth. Hearts from 2 to ... Areas of individual myocytes varied widely, with the distribution skewed toward larger cells. The standard deviation increased ...https://www.cdc.gov/niosh/nioshtic-2/00205787.html
Antiapoptotic Actions of Methyl Gallate on Neonatal Rat Cardiac Myocytes Exposed to H2O2
... in cardiac myocyte medium (CMM) supplemented with 5% FBS, 1% cardiac myocyte growth supplement, and 1% penicillin/streptomycin ... Antiapoptotic Actions of Methyl Gallate on Neonatal Rat Cardiac Myocytes Exposed to H2O2. Sandhya Khurana,1 Amanda ... S. A. Cook and P. A. Poole-Wilson, "Cardiac myocyte apoptosis," European Heart Journal, vol. 20, no. 22, pp. 1619-1629, 1999. ... M. T. Crow, K. Mani, Y.-J. Nam, and R. N. Kitsis, "The mitochondrial death pathway and cardiac myocyte apoptosis," Circulation ...https://www.hindawi.com/journals/omcl/2014/657512/
Cardiac myocyte | definition of Cardiac myocyte by Medical dictionary
Cardiac myocyte explanation free. What is Cardiac myocyte? Meaning of Cardiac myocyte medical term. What does Cardiac myocyte ... Looking for online definition of Cardiac myocyte in the Medical Dictionary? ... redirected from Cardiac myocyte). Also found in: Dictionary, Thesaurus, Encyclopedia.. Related to Cardiac myocyte: cardiac ... Cardiac myocyte , definition of Cardiac myocyte by Medical dictionary https://medical-dictionary.thefreedictionary.com/Cardiac+ ...http://medical-dictionary.thefreedictionary.com/Cardiac+myocyte
Angiotensin II Activates RhoA in Cardiac Myocytes | Circulation Research
Ang II-induced translocation of RhoA from the soluble to the particulate fractions in cardiac myocytes. A, Cardiac myocytes ... In vivo ADP-ribosylation of Rho in cardiac myocytes. Cardiac myocytes were incubated with the indicated concentrations of C3 ... Colocalization of polymerized actin and troponin T in cardiac myocytes. Cardiac myocytes stimulated with Ang II for 30 minutes ... Ang II-induced sarcomeric actin organization in cardiac myocytes. Cardiac myocytes grown on gelatin-coated glass coverslips ...http://circres.ahajournals.org/content/82/6/666
British Library EThOS: Actions of NAADP and other agents in cardiac myocytes
In cardiac myocytes, NAADP is thought to stimulate calcium release from acidic stores which then bolsters filling and release ... Basal cardiac rate is a major determinant in cardiac mortality and compounds which specifically affect rate have clinical ... Modulation of cardiac rate and contraction through calcium-dependent and independent means are of central import to the ability ... In contractile myocytes, photorelease of NAADP caused significant increase in calcium transient amplitude and velocity of ...http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.644692
CiNii 論文 - Haloperidol Prolongs Diastolic Phase of Ca^|2+| Transient in Cardiac Myocytes ...
Haloperidol Prolongs Diastolic Phase of Ca^,2+, Transient in Cardiac Myocytes * * Ishida Hideyuki ISHIDA Hideyuki ... Kinetics of chlorpromazine block of sodium channels in single guinea pig cardiac myocytes OGATA N. ... transient and on cell motion in cultured cardiac myocytes, as well as the pathways involving the HPL-induced abnormality of Ca, ... Effects of overexpression of the Na^+-Ca^,2+, exchanger on [Ca^,2+,]_i transients in murine ventricular myocytes YAO A. ...https://ci.nii.ac.jp/naid/10008308164
Effects of IGF-1 on and Channels via PI3K/Akt Signaling in Neonatal Cardiac Myocytes
inward rectifier currents of neonatal cardiac myocytes. These results in normal neonatal rat cardiac myocytes are in agreement ... IGF-1 is thought to contribute to cardiac myocyte hypertrophy and, at the same time protect cardiac myocytes from ... is reported to be a significant contributor to the cardiac arrhythmias associated with hypertrophy of cardiac myocytes [26, 27 ... we previously observed in eccentrically hypertrophied adult rat cardiac myocytes and not in normal adult rat cardiac myocytes ...https://www.hindawi.com/journals/ijcb/2012/712153/
Multimodal Regulation of Cardiac Myocyte Proliferation | Circulation Research
Efficient cardiac regeneration is closely associated with the ability of cardiac myocytes to proliferate. Fetal or neonatal ... To (re)initiate cardiac myocyte proliferation in adult mammalian hearts, a thorough understanding of the molecular circuitry ... Here, we review the current knowledge in the field focusing on the withdrawal of cardiac myocytes from the cell cycle during ... induction of cardiac myocyte proliferation is an attractive therapeutic option to cure the injured heart and prevent heart ...http://circres.ahajournals.org/content/121/3/293?download=true
A Novel Anionic Inward Rectifier in Native Cardiac Myocytes | Circulation Research
At least six distinct types of sarcolemmal Cl− currents have been functionally identified in cardiac myocytes.1 2 3 4 5 These ... PKC regulation of cardiac CFTR Cl− channel function in guinea pig ventricular myocytes. Am J Physiol. 1998;275:C293-C302. ... A Novel Anionic Inward Rectifier in Native Cardiac Myocytes. Dayue Duan, Lingyu Ye, Fiona Britton, Burton Horowitz, Joseph R. ... A similar ICl.ir was also observed in guinea pig cardiac myocytes. The properties of ICl.ir are consistent with currents ...http://circres.ahajournals.org/content/86/4/e63
Simvastatin Attenuates Oxidant-Induced Mitochondrial Dysfunction in Cardiac Myocytes | Circulation Research
Simvastatin Attenuates Oxidant-Induced Mitochondrial Dysfunction in Cardiac Myocytes. Steven P. Jones, Yasushi Teshima, ... Simvastatin Attenuates Oxidant-Induced Mitochondrial Dysfunction in Cardiac Myocytes. Steven P. Jones, Yasushi Teshima, ... Simvastatin Attenuates Oxidant-Induced Mitochondrial Dysfunction in Cardiac Myocytes. Steven P. Jones, Yasushi Teshima, ...http://circres.ahajournals.org/content/early/2003/09/25/01.RES.0000097262.21507.DF
The Mitochondrial Death Pathway and Cardiac Myocyte Apoptosis | Circulation Research
In cardiac myocytes, hypoxia increases p53 levels, and p53 alone suffices to kill normoxic cardiac myocytes.123 Despite this, ... To elucidate whether cardiac myocyte apoptosis plays a causal role in the pathogenesis of any cardiac syndrome, it is necessary ... Inhibition of cardiac myocyte apoptosis improves cardiac function and abolishes mortality in the peripartum cardiomyopathy of ... Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac ...http://circres.ahajournals.org/content/95/10/957.full
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