α-Smooth muscle actin-IR reveals the submucosal smooth muscle layer (red), which lies beneath the epithelium demarcated by the ... To assess whether estrogen modulates smooth muscle-induced outgrowth by way of BMP4, we grew vaginal smooth muscle cells in ... Estrogen downregulates BMP4 expression in vaginal smooth muscle. Vaginal cells, including smooth muscle cells, express estrogen ... Vaginal smooth muscle cells immunostained for α-smooth muscle actin (red) were grown on collagen-coated plastic. DRG neurons ...http://www.jneurosci.org/content/33/3/1050
The Integrin Very Late Antigen-4 Is Expressed in Human Smooth Muscle Cell | Circulation Research
Expression of smooth muscle and non-muscle myosin heavy chains in cultured vascular smooth muscle cells. J Biol Chem. 1986;261: ... Expression of smooth muscle-specific α-isoactin in cultured vascular smooth muscle cells: relationship between growth and ... Gabbiani G, Schmidt E, Winter S, Chaponier C, De Chastonay C. Vascular smooth muscle cells differ from other smooth muscle ... Cell cycle versus density dependence of smooth muscle alpha actin expression in cultured aortic smooth muscle cells. J Cell ...http://circres.ahajournals.org/content/80/2/159
Adenosine triphosphate (ATP) inhibits IP3-evoked Ca2+ release in smooth muscle via P2Y1 receptors | Journal of Cell Science
In smooth muscle, ATP, acting via P2Y receptors (P2YR), may act as an inhibitory neurotransmitter. The underlying mechanism(s) ... However, in the present study, ATP evoked transient Ca2+ increases in only ∼10% of voltage-clamped single smooth muscle cells. ... These results do not support activation of KCa as the major mechanism underlying inhibition of smooth muscle activity. ... Adenosine triphosphate (ATP) inhibits IP3-evoked Ca2+ release in smooth muscle via P2Y1 receptors ...http://jcs.biologists.org/content/early/2012/08/15/jcs.108498
MicroRNA miR145 Regulates TGFBR2 Expression and Matrix Synthesis in Vascular Smooth Muscle CellsNovelty and Significance |...
Smooth muscle α-actin RNA and protein (ACTA2) showed a similar expression profile in cocultured aortic smooth muscle cells when ... miR145 Regulates TGFβ-Pathway Genes and Matrix Gene Expression in Smooth Muscle Cells. In smooth muscle cells, TGFβ signaling ... We show that in smooth muscle cells, TGFβ activates both matrix genes and smooth muscle-specific genes, but miR145 specifically ... Endothelial cells induce miR-143/145 expression in vascular smooth muscle cells. Human aortic smooth muscle cells were ...http://circres.ahajournals.org/content/116/1/23
TGC Theory Smooth muscle vs Tunica - Thunder's Place
TGC Theory Smooth muscle vs Tunica Ok so my measurements are sporadic I decided to just look on here for info to fix it. I ... For example smooth muscle must relax to allow for an erection. It was a bravura attempt by Remek and Iguana and I learnt ... Increasing smooth muscle mass in the penis. ticktickticker. Penis Enlargement. 53. 04-10-2017 11:53 AM. ... So I need to have a girth heavy exercises to increase my smooth muscle in my penis. I have gotten one persons input on this I ...https://www.thundersplace.org/penis-enlargement-basics/tgc-theory-smooth-muscle-vs-tunica.html
Tissue Diagnosis - Zeta Corporation
Smoothelin is a novel smooth muscle-specific marker expressed only in terminally differentiated smooth muscle cells as part of ... smoothelin expression is absent or limited in noncontractile and proliferative smooth muscle cells or cells with smooth muscle- ... Smooth muscle tumors: Positive for MSA, SMA, h-caldesmon, desmin. H-caldesmon is the most specific for demonstrating a smooth ... Unlike traditional smooth muscle markers (ie, SMA and MSA), ... Skeletal muscle tumors: Positive for myogenin, MyoD1, and ...http://zeta-corp.com/tissue-diagnosis/
pain free labour: Evidence based practice to support a pain free labour - Three
If uterine smooth muscle was so different from other smooth muscle then it would be in a section of its own. If uterine smooth ... of Anatomy and Physiology on muscle tissue and nowhere do they say that uterine smooth muscle is any different to smooth muscle ... Striated muscle is voluntary and attached to our skeleton so that we can skip and dance. Smooth muscle is not voluntary, we ... that of not recognising a fourth muscle group. So, why do so many women today experience uterine smooth muscle contractions as ...http://painfreelabour.blogspot.com/2012/12/evidence-based-practice-to-support-pain.html
... cytokines and intracellular activation of smooth muscle proliferation. *Epigenetic change and phenotype in proliferating smooth ... Control of smooth muscle proliferation in vivo. *Manipulation of the PDGF-BB and PDGF-Rβ signaling axis; regulation of ... Han TY, Lourenssen S, Miller KG, and Blennerhassett MG (2015). Intestinal smooth muscle phenotype determines enteric neuronal ... Inflammatory cytokines promote growth of intestinal smooth muscle cells by induced expression of PDGF-Rβ. J Cell Mol. Med. 18(3 ...http://deptmed.queensu.ca/faculty/michael_blennerhassett/research
Evidence for a visceral smooth muscle abnormality in Okamoto spontaneous hypertension.
Muscle Contraction / drug effects*. Muscle Relaxation / drug effects. Muscle, Smooth / physiopathology*. Rats. Rats, Inbred ... 4. SHR fundus smooth muscle shows the same modification of reactivity to Ba2+, Sr2+, Ca2+ and diazoxide that was previously ... described in arterial smooth muscle. This indicates that the cellular modification responsible for the increase of vascular ... just an adaptation induced by the high arterial blood pressure we tested the contractile response of a visceral smooth muscle ...http://www.biomedsearch.com/nih/Evidence-visceral-smooth-muscle-abnormality/870125.html
Roles of Mast Cell Proteases in Airways: Airway Smooth Muscle Contraction
Airway Smooth Muscle Contraction Hyperresponsiveness to mast cell-derived mediators (eg, histamine) is a distinctive feature of ... to a muscle bath containing dog bronchial smooth muscle greatly increased the contractile response of the smooth muscle to ... Induced Airway Smooth Muscle Relaxation. Because mast cell proteases cleave the VIP molecule, we studied their effect on VIP- ... Incubation of the smooth muscle with purified tryptase alone (0.09 μg/ml) did not affect resting tension, but tryptase ...http://www.levelofhealth.com/airways/roles-of-mast-cell-proteases-in-airways-airway-smooth-muscle-contraction.html
PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells - Semantic...
... in the bradykinin-induced IL-8 release from a human airway smooth muscle cell line and the underlying molecular mechanisms of ... Epac1 and Epac2 act in concert to modulate inflammatory properties of airway smooth muscle via signaling to the Ras-like GTPase ... BACKGROUND Airway smooth muscle contributes to the pathogenesis of pulmonary diseases by secreting inflammatory mediators such ... Epac as a novel effector of airway smooth muscle relaxation. *Sara S Roscioni. , Harm Maarsingh. , +5 authors. Martina Schmidt ...https://www.semanticscholar.org/paper/PKA-and-Epac-cooperate-to-augment-bradykinin-induc-Roscioni-Kistemaker/45af31b28236123860d662d7057a477d02dcbc79
Human Gastric Smooth Muscle Cells (HGSMC) | Creative Bioarray
Smooth muscle contraction is critical to peristalsis in the human stomach and the contraction may be mediated by activation of ... Smooth muscle is responsible for the contractility of hollow organs, such as blood vessels, the gastrointestinal tract, the ... In vitro study also shows that gastric smooth muscle cells express ET and eNOS and both calcium and sodium may be involved as ... HGSMC are characterized by immunofluorescent method with antibodies to &ALPHA;-smooth muscle actin and desmin. HGSMC are ...https://www.creative-bioarray.com/Human-Gastric-Smooth-Muscle-Cells-HGSMC-CSC-7779W-item-1834.htm
Dedifferentiation, redifferentiation and bundle formation of smooth muscle cells in tissue culture: the influence of cell...
Smooth muscle from newborn guinea-pig vas deferens was enzymically dispersed into single cells or small clumps and grown in ... Most single smooth muscle cells gradually lost their typical ultrastructural features and contractile properties during the ... The relation of these findings to the process of wound healing in smooth muscle tissues in vivo is discussed. ... The process of dedifferentiation and proliferation was delayed in those smooth muscle cells which had sympathetic nerve fibres ...http://dev.biologists.org/content/32/2/297
The contractile apparatus and mechanical properties of airway smooth muscle | European Respiratory Society
The molecular basis for the length-dependence of tension in smooth muscle differs from that in skeletal muscle, and may involve ... In airway smooth muscle, actomyosin activation is initiated by the phosphorylation of the 20 kDa light chain of myosin; but ... The contractile apparatus and mechanical properties of airway smooth muscle Message Subject (Your Name) has sent you a message ... The contractile apparatus and mechanical properties of airway smooth muscle. SJ Gunst, DD Tang ...http://erj.ersjournals.com/content/15/3/600
A Retinoic Acid-Induced Clonal Cell Line Derived From Multipotential P19 Embryonal Carcinoma Cells Expresses Smooth Muscle...
The smooth muscle alpha-actin gene promoter is differentially regulated in smooth muscle versus non-smooth muscle cells. J Biol ... Correlation between the distribution of smooth muscle or non muscle myosins and alpha-smooth muscle actin in normal and ... Expression of smooth muscle and nonmuscle myosin heavy chains in cultured vascular smooth muscle cells. J Biol Chem. 1986;261: ... Smooth muscle myosin heavy chain marks exclusively the smooth muscle lineage during mouse embryogenesis. Circ Res. 1994;75:803- ...http://circres.ahajournals.org/content/76/5/742
Muscularis mucosae - Wikipedia
The muscularis mucosae is composed of several thin layers of smooth muscle fibers oriented in different ways which keep the ... It is present in a continuous fashion from the esophagus to the upper rectum (the exact nomenclature of the rectum's muscle ... The lamina muscularis mucosae (or muscularis mucosae) is a thin layer (lamina) of muscle of the gastrointestinal tract, located ... layers is still being debated). A discontinuous muscularis mucosae-like muscle layer is present in the urinary tract, from the ...https://en.wikipedia.org/wiki/Muscularis_mucosae
Smooth muscle tissue - Wikipedia
BBC - baby born with smooth muscle condition has 8 organs transplanted Smooth muscle antibody Stomach smooth muscle identified ... 1 in smooth muscle, compared to ~6:1 in skeletal muscle and 4:1 in cardiac muscle. Smooth muscle does not contain the protein ... Smooth muscle-containing tissue needs to be stretched often, so elasticity is an important attribute of smooth muscle. Smooth ... make the entire smooth muscle tissue contract with them. The smooth muscle is the only type of muscle without the ability to be ...https://en.wikipedia.org/wiki/Smooth_muscle_tissue
Smooth muscle tumour - Wikipedia
Smooth muscle tumours show a smooth muscle differentiation. There are two main types of smooth muscle tumour: the benign ...https://en.wikipedia.org/wiki/Smooth_muscle_tumour
Vascular smooth muscle - Wikipedia
Vascular smooth muscle refers to the particular type of smooth muscle found within, and composing the majority of the wall of ... Vascular smooth muscle refers to the particular type of smooth muscle found within, and composing the majority of the wall of ... Mural cell Image of smooth muscle in the arterial walls Smooth muscle in stomach wall. ... Vascular smooth muscle contracts or relaxes to change both the volume of blood vessels and the local blood pressure, a ...https://en.wikipedia.org/wiki/Vascular_smooth_muscle
Anti-smooth muscle antibody - Wikipedia
Anti-smooth muscle antibodies are antibodies (immunoglobulins) formed against smooth muscle. These antibodies are typically ... "Immunoglobulin deposition in liver of patients with active chronic hepatitis and antibody against smooth muscle". British ...https://en.wikipedia.org/wiki/Anti-smooth_muscle_antibody
Congenital smooth muscle hamartoma - Wikipedia
Congenital smooth muscle hamartoma is typically a skin colored or lightly pigmented patch or plaque with hypertrichosis. Skin ...https://en.wikipedia.org/wiki/Congenital_smooth_muscle_hamartoma
Single-unit smooth muscle - Wikipedia
Single-unit smooth muscle, or visceral smooth muscle is a type of smooth muscle found in the uterus, gastro-intestinal tract, ... In SUVSM, a single smooth muscle cell in a bundle is innervated by an autonomic nerve fiber. An action potential can be ... Because of its myogenic nature, single-unit smooth muscle is usually active, even when it's not receiving any neural ... Single-unit visceral smooth muscle is myogenic; it can contract regularly without input from a motor neuron (as opposed to ...https://en.wikipedia.org/wiki/Single-unit_smooth_muscle
Intercellular communication in smooth muscle | SpringerLink
Sperelakis, N., Electric field model: An alternate mechanism for cell-to-cell propagation in cardiac muscle and smooth muscle. ... Gabella, G., Smooth muscle cell junctions and structural aspects of contraction. Br. med. Bull.35 (1979) 213-218.PubMedGoogle ... Huizinga, J. D., and Chow, E., Electrotonic current spread in colonic smooth muscle. Am. J. Physiol.254 (1988) G702-G710.PubMed ... Cheung, D. W., and Daniel, E. E., Comparative study of the smooth muscle layers of the rabbit duodenum. J. Physiol., Lond.309 ( ...https://link.springer.com/article/10.1007/BF01919140
Human smooth muscle cell culture.
... Pippa Deex deexpj at cf.ac.uk Wed Jun 26 06:43:16 EST 1996 *Previous message: Antibodies ... I am planning to set up a co-culture system for human endothelial cells and human VASCULAR smooth muscle cells. I would be ... really interested to find out about methods of extraction and primary culture of human vascular smooth muscle cells, if anyone ...http://www.bio.net/bionet/mm/methods/1996-June/046195.html
Smooth muscle tumor of uncertain malignant potential - Wikipedia
Smooth muscle tumor of uncertain malignant potential, abbreviated STUMP, is an uncommon tumor of the uterine smooth muscle that ... Ng JS, Han A, Chew SH, Low J (August 2010). "A clinicopathologic study of uterine smooth muscle tumours of uncertain malignant ... Coagulative tumor cell necrosis is common in clinically malignant smooth muscle cell tumors. It consists of an abrupt ... Ip PP, Cheung AN, Clement PB (July 2009). "Uterine smooth muscle tumors of uncertain malignant potential (STUMP): a ...https://en.wikipedia.org/wiki/Smooth_muscle_tumor_of_uncertain_malignant_potential